Comparative Immunology Microbiology and Infectious Diseases最新文献

Prevalence and associated risk factors of Brucella abortus and Brucella melitensis in humans and cattle populations: A comprehensive study. 人类和牛群中流产布鲁氏菌和梅毒布鲁氏菌的流行率及相关风险因素：一项综合研究。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-11-13 DOI: 10.1016/j.cimid.2024.102276

Ihsan Ullah, Shumaila Naz, Umer Sadique Khattak, Muhammad Saeed, Noor Ul Akbar, Sania Rauf

{"title":"Prevalence and associated risk factors of Brucella abortus and Brucella melitensis in humans and cattle populations: A comprehensive study.","authors":"Ihsan Ullah, Shumaila Naz, Umer Sadique Khattak, Muhammad Saeed, Noor Ul Akbar, Sania Rauf","doi":"10.1016/j.cimid.2024.102276","DOIUrl":"https://doi.org/10.1016/j.cimid.2024.102276","url":null,"abstract":"<p><p>A zoonotic disease unique to South Asia, brucellosis causes major public health and financial problems, notably in Pakistan. This research aimed to ascertain the molecular frequency of Brucella abortus and Brucella melitensis in humans and cattle and to pinpoint related risk factors in the Southern Khyber Pakhtunkhwa, Pakistan, districts. A total of 800 blood samples, 600 from cattle and 200 from humans, were gathered and examined using traditional PCR targeting the IS711 locus. In humans, the molecular frequency of Brucella melitensis and Brucella abortus was 16.5 %; in cattle, it was 9.1 %. Risk factor analysis in cattle revealed that seasonality, geographic location, sex, and insemination method significantly impacted brucellosis prevalence· Higher risk was observed in female cattle, those naturally inseminated, and during the summer months, particularly in regions such as Bannu· In humans, univariate logistic regression identified potential risk factors, including age (25-50 years), rural residency, lower socioeconomic status, female gender, direct contact with animals, and consumption of raw animal products. However, none of these factors reached statistical significance. The findings underscore the importance of continuous surveillance and targeted preventive measures to control brucellosis transmission between cattle and humans. Understanding the molecular prevalence and risk factors can guide public health strategies and improve livestock management practices to mitigate this zoonotic disease.</p>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"102276"},"PeriodicalIF":2.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cladistics and population structure analysis of Anaplasma marginale (Rickettsiales: Anaplasmataceae) in Haryana, India based on genes encoding the major surface proteins 基于编码主要表面蛋白的基因对印度哈里亚纳邦的边缘疟原虫（立克次体：疟原虫科）进行支系和种群结构分析。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-11-08 DOI: 10.1016/j.cimid.2024.102274

Aman D. Moudgil , Anil K. Nehra, Sukhdeep Vohra

{"title":"Cladistics and population structure analysis of Anaplasma marginale (Rickettsiales: Anaplasmataceae) in Haryana, India based on genes encoding the major surface proteins","authors":"Aman D. Moudgil , Anil K. Nehra, Sukhdeep Vohra","doi":"10.1016/j.cimid.2024.102274","DOIUrl":"10.1016/j.cimid.2024.102274","url":null,"abstract":"<div><div><em>Anaplasma marginale</em>, a tick-borne obligate intracellular rickettsia is incriminated to cause heavy economic losses throughout the tropical and subtropical regions, including India. However, studies highlighting the phylogeography and demographic dynamics of <em>A. marginale</em> are very scant from India. Thus, the present study assessed the cladistics and population structure of <em>Anaplasma marginale</em> based on the genes encoding the major surface proteins (MSP) 4 and 5. The cladistics based on phylogenetic tree including the sequences generated herein with the GenBank archived sequences of <em>A. marginale</em> was performed. The relationship between <em>A. marginale</em> haplotypes based on both the genetic markers was estimated by performing median joining (MJ) haplotype network analysis. Demographic dynamics involving population diversity indices and neutrality indices was also performed. The cladistics and MJ haplotype network analysis corresponding to both the markers demonstrated the presence of three distinct clades (1−3) of <em>A. marginale</em>. Population structure analysis revealed low nucleotide (0.00236 ± 0.00064 and 0.00955 ± 0.00101) and haplotype (0.321 ± 0.073 and 0.493 ± 0.083) diversities for the MSP4 and MSP5 genes, respectively. High genetic structuring and low gene flow [Nm values ranging between 0.044481 and 0.208337 for the MSP4 gene and 0.032735 (clades 1 and 2) for the MSP5 gene] was also recorded among the different clades of <em>A</em>. <em>marginale</em>, based on both genetic markers. The present study highlighted the presence of different clades of <em>A. marginale</em> distributed worldwide. The isolates circulating in north India belonged to the dominant clade prevalent throughout the globe.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102274"},"PeriodicalIF":2.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular typing of Protoparvovirus carnivoran 1 in Egyptian cats diagnosed with feline panleukopenia 对确诊患有猫泛白细胞减少症的埃及猫进行肉食原病毒 1 的分子分型。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-31 DOI: 10.1016/j.cimid.2024.102273

Mahmoud S. Safwat , Samah El-Sayed M. , Mohamed E. Ali , Omar S. Saeed , Haitham M. Amer , Othman N.O. Mansour , Ayah M. Hassan , Manar M. Farouk

{"title":"Molecular typing of Protoparvovirus carnivoran 1 in Egyptian cats diagnosed with feline panleukopenia","authors":"Mahmoud S. Safwat , Samah El-Sayed M. , Mohamed E. Ali , Omar S. Saeed , Haitham M. Amer , Othman N.O. Mansour , Ayah M. Hassan , Manar M. Farouk","doi":"10.1016/j.cimid.2024.102273","DOIUrl":"10.1016/j.cimid.2024.102273","url":null,"abstract":"<div><div>Feline panleukopenia (FPL) in cats is caused by either feline parvovirus (FPV) or canine parvovirus (CPV-2), which belong to the same species “<em>Protoparvovirus carnivoran 1”</em>. While FPV is widely recognized as the principal cause of FPL, CPV-2 has been detected at a higher rate than FPV in sick cats in a recent Egyptian study. To assess this conflict, the present study aimed to determine which <em>Protoparvovirus carnivoran 1</em> is commonly associated with FPL in Egyptian cats. From Dec-2022 to Jan-2024, 43 cats presenting with acute gastroenteritis and testing positive for FPL using in-clinic assay, SNAP® parvo, were tested for <em>Protoparvovirus carnivoran 1</em> DNA using conventional PCR. Typing of <em>Protoparvovirus carnivoran 1</em> was conducted by partial VP2 gene sequencing. Additional epidemiological aspects of the disease were investigated, including seasonal pattern, case-fatality rate, median survival time to death, and the association between FPL outcomes and selected factors like age, sex, vaccination status, and clinical signs (vomiting and diarrhea). All cats tested positive for <em>Protoparvovirus carnivoran 1</em> DNA and FPV was detected in all cats with strong PCR amplicons (n=39). The following seasonal pattern was recorded: cases emerging in autumn, peaking during winter, declining in spring, and disappearing in summer. The case-fatality rate was 41.6 %, and the median time to death was two days. None of the studied factors affected FPL outcomes. In conclusion, FPL in Egyptian cat populations is primarily caused by FPV, not CPV-2, and is particularly prevalent in winter.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102273"},"PeriodicalIF":2.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The first report of concurrent infection of hemorrhagic septicemia with foot and mouth disease in cattle in Bangladesh 孟加拉国首次报告牛同时感染出血性败血症和口蹄疫的病例

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-29 DOI: 10.1016/j.cimid.2024.102272

Md. Abdur Rahman , Farah Zereen , Md. Golzar Hossain , Md. Al-Amin , Jahangir Alam , Masaru Shimada , Md. Tanvir Rahman , Sukumar Saha

{"title":"The first report of concurrent infection of hemorrhagic septicemia with foot and mouth disease in cattle in Bangladesh","authors":"Md. Abdur Rahman , Farah Zereen , Md. Golzar Hossain , Md. Al-Amin , Jahangir Alam , Masaru Shimada , Md. Tanvir Rahman , Sukumar Saha","doi":"10.1016/j.cimid.2024.102272","DOIUrl":"10.1016/j.cimid.2024.102272","url":null,"abstract":"<div><div>This study aimed to investigate the concurrent infection of <em>Pasteurella multocida</em> (<em>P. multocida</em>) type B:2, which causes Hemorrhagic Septicemia (HS), with cases of Foot and Mouth Disease (FMD) outbreaks in cattle in Bangladesh between March and December 2023. Samples were collected from 11 distinct outbreak areas, totaling 102 samples. These included 54 FMD samples (saliva, tissue epithelium, and morbid tissues such as lung, spleen, and heart) and 54 HS samples (nasal swabs and morbid tissues) from 50 cattle of various ages and sexes, all showing clinical signs of suspected concurrent HS and FMD infection. After sample processing, molecular detection of FMDV and its serotypes was performed using Reverse Transcriptase PCR (RT-PCR) with universal and serotype-specific primers. The HS-causing agent, <em>P. multocida</em> type B:2, was initially identified through cultural and morphological characteristics on various media, followed by Gram’s and methylene blue staining, biochemical tests, and pathogenicity tests through inoculation of isolates into mice. Finally, molecular detection of <em>P. multocida</em> type B:2 was confirmed using PCR with specific primers. Forty-five (83 %) of the 54 FMD suspected samples tested positive for FMDV, with 53 % of these positive for serotype ‘O,’ 17 % for serotype ‘A,’ and 6 % for mixed serotypes ‘O’ and ‘A.’ Among the FMDV-positive samples, 17 (38 %) of the HS-suspected samples tested positive for concurrent infection with <em>P. multocida</em> type B:2. The study reveals that FMDV-induced acute immunosuppression in cattle can lead to complications from concurrent infections, particularly those caused by <em>P. multocida</em> type B:2, resulting in HS alongside FMD.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102272"},"PeriodicalIF":2.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142560776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring interplay between bovine milk-derived α-lactalbumin, pathogenic bacteria, and bacteriophages at the molecular interface of inflammation 探索牛乳衍生的α-乳白蛋白、致病菌和噬菌体在炎症分子界面上的相互作用。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-28 DOI: 10.1016/j.cimid.2024.102271

Darab Ghadimi , Aysel Şahi̇n Kaya , Sandra Krüger , Christoph Röcken , Heiner Schäfer , Jumpei Uchiyama , Shigenobu Matsuzaki , Wilhelm Bockelmann

{"title":"Exploring interplay between bovine milk-derived α-lactalbumin, pathogenic bacteria, and bacteriophages at the molecular interface of inflammation","authors":"Darab Ghadimi , Aysel Şahi̇n Kaya , Sandra Krüger , Christoph Röcken , Heiner Schäfer , Jumpei Uchiyama , Shigenobu Matsuzaki , Wilhelm Bockelmann","doi":"10.1016/j.cimid.2024.102271","DOIUrl":"10.1016/j.cimid.2024.102271","url":null,"abstract":"<div><div>There is so far no available data about how the additive, synergistic, or antagonistic effects of the combined form of alpha-lactalbumin (α-La) and bacteriophages might modulate the cellular milieu of the host-pathogen interface. A co-culture of colonocytes and hepatocytes was stimulated with Pseudomonas aeruginosa PAO1 in the presence of KPP22 phage and incubated for 6 hours in medium alone or medium supplemented with bovine milk-origin α-La. The combination of KPP22 phage and α-La significantly inhibited P.a PAO1-elicited secretion of IL-1β, IL-6, and ICAM-1, which are the mediators and enzymes associated with the inflammatory response to an infectious-inflamed milieu. Cell viability was higher in the P.a PAO1+ KPP22 phage group compared to the P.a PAO1alone group. KPP22 phage and α-La, either alone or in combination, rescued P.a PAO1-induced aberrant PGE1/PGE2 production ratios. The convergence of ingested α-La and phages mitigates pro-inflammatory mediators. α-La leads to an increased sensitivity of opportunistic pathogenic bacteria to phages. Structural, functional, or immunological similarities between ingested α-La and phages play an important role in the mitigation of infection-driven pathobiological processes.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102271"},"PeriodicalIF":2.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection and molecular characterization of avian polyomavirus in budgerigar and non-budgerigar psittacine species in bird markets of Pakistan 巴基斯坦鸟类市场虎皮鹦鹉和非虎皮鹦鹉物种中禽类多瘤病毒的检测和分子特征。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-28 DOI: 10.1016/j.cimid.2024.102261

Zakia Khatoon , Aayesha Riaz , Arfan Yousaf , Mazhar Qayyum , Iqra Zarif , Irtaza Hassan Khan , Ruqia Mehmood Baig , Evelyn Saba

{"title":"Detection and molecular characterization of avian polyomavirus in budgerigar and non-budgerigar psittacine species in bird markets of Pakistan","authors":"Zakia Khatoon , Aayesha Riaz , Arfan Yousaf , Mazhar Qayyum , Iqra Zarif , Irtaza Hassan Khan , Ruqia Mehmood Baig , Evelyn Saba","doi":"10.1016/j.cimid.2024.102261","DOIUrl":"10.1016/j.cimid.2024.102261","url":null,"abstract":"<div><div>Avian Polyomaviruses are imposing severe health problems in budgerigars, non-budgerigar Psittacine species, and non-psittacine species all over the world, including Pakistan. It marks future challenges for aviculturists and pet store owners, causing significant financial losses. This study emphasizes the occurrence and molecular characterization of polyomaviruses in budgerigars and non-budgerigar Psittacine species. Thirty-five feather Samples of adult birds and 15 tissue samples of deceased birds were collected for the detection of Avian polyomavirus based on the VP1 gene. Screening of samples by PCR revealed the presence of 550 bp VP1 gene in deceased nestlings of two lovebirds and four budgerigars, while the feather samples of adult birds were all negative for VP1 gene. The overall positive rate of APV in Psittacine birds was 6/50 (12 %), and the distribution frequency of virus among species was 4/19 (20 %) in Budgerigars and 2/31 (6.4 %) in non-budgerigar. Positive samples were subjected to partial sequencing which showed a nucleotide similarity index of VP1 gene between 97.46 % & 99.6 % with reference sequences in GenBank. The main problem that researchers are dealing with is the scarcity of data on the prevalence and identification of APV in Pakistan. This study is a milestone for further research on APV for the diagnosis and development of vaccines.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102261"},"PeriodicalIF":2.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular prevalence, phylogenetic analysis, and PCR-based detection of Brucella melitensis in humans and cattle in Southern Khyber Pakhtunkhwa, Pakistan 巴基斯坦南开伯尔-普赫图赫瓦省人和牛中布鲁氏菌的分子流行率、系统发育分析和基于 PCR 的检测

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-28 DOI: 10.1016/j.cimid.2024.102262

Ihsan Ullah , Shumaila Naz , Umer Sadique Khattak , Muhammad Saeed , Noor ul Akbar , Sania Rauf

{"title":"Molecular prevalence, phylogenetic analysis, and PCR-based detection of Brucella melitensis in humans and cattle in Southern Khyber Pakhtunkhwa, Pakistan","authors":"Ihsan Ullah , Shumaila Naz , Umer Sadique Khattak , Muhammad Saeed , Noor ul Akbar , Sania Rauf","doi":"10.1016/j.cimid.2024.102262","DOIUrl":"10.1016/j.cimid.2024.102262","url":null,"abstract":"<div><div>Brucellosis is a bacterial disease due to <em>Brucella melitensis</em>, considered a zoonotic agent affecting humans and animals, especially in areas with high disease occurrence, south Khyber Pakhtunkhwa, Pakistan. This work was designed to evaluate the molecular rate of <em>B. melitensis</em> in humans and cattle species and also to perform a phylogenetic analysis between both species. A cross-sectional survey involving 800 participants, including 600 cattle and 200 human participants, underwent blood sample collection with conventional PCR and IS711 locus PCR amplification and Sanger sequencing. The findings detected <em>Brucella melitensis</em> in 37 of the 800 samples, with a molecular prevalence of 3.1 % in cattle and 9 % in humans. The molecular trees play a role in zoonotic transmission and point to the necessity of a further unified approach toward the management of brucellosis in both humans and animals. This is further backed by the use of 95 % C.I for the prevalence rates making the results statistically robust. This research shows that using the IS711 insertion sequence is an efficient and selective method for identifying Brucella species.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102262"},"PeriodicalIF":2.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142560775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, perception and attitude about Crimean-Congo Haemorrhagic Fever (CCHF) among veterinary students and professionals of Spain 西班牙兽医专业学生和专业人员对克里米亚-刚果出血热（CCHF）的认识、看法和态度。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-20 DOI: 10.1016/j.cimid.2024.102260

Patricia Bañuls , Ángela Galán-Relaño , Antonio Romero-Salmoral , Lidia Gómez-Gascón , Carmen Tarradas , Rafael J. Astorga Márquez , Inmaculada Luque , Belén Huerta

{"title":"Knowledge, perception and attitude about Crimean-Congo Haemorrhagic Fever (CCHF) among veterinary students and professionals of Spain","authors":"Patricia Bañuls , Ángela Galán-Relaño , Antonio Romero-Salmoral , Lidia Gómez-Gascón , Carmen Tarradas , Rafael J. Astorga Márquez , Inmaculada Luque , Belén Huerta","doi":"10.1016/j.cimid.2024.102260","DOIUrl":"10.1016/j.cimid.2024.102260","url":null,"abstract":"<div><div>The Crimean-Congo haemorrhagic fever (CCHF) is a tropical viral zoonosis first reported in Spain with 17 detected cases since 2010–2024. Health professionals, including veterinarians, play a crucial role in controlling and preventing this disease. This study aimed to analyse and compare the knowledge, perceptions, and attitudes of veterinary students and professionals in Spain regarding CCHF and zoonoses in general. Additionally, the study highlighted the value of epidemiological surveys as a tool for identifying knowledge gaps related to specific diseases. A cross-sectional survey was conducted from January to April 2024 among 4th and 5th-year veterinary students, Masters and Doctorate students, and veterinarians from the public and private sectors using a validated online questionnaire. A total of 135 individuals participated, 80.7 % professionals and 19.3 % students. The study found that 76.9 % of students and 64.2 % of veterinarians had good or very good knowledge of CCHF, yet significant gaps remained, particularly in epidemiology and diagnosis. Notably, only 34.8 % had good or very good knowledge of the disease’s situation in Spain, and many respondents felt their training and the information provided by official sources were inadequate. Additionally, the perception of infection risk from pets and attitudes towards preventing zoonoses through medication, vaccination, or regular analysis were concerning. Despite CCHF being an emerging disease in Spain, this survey—the first in Spain and Europe—reveals that veterinarians’ knowledge and attitudes in affected regions are not as advanced as needed, underscoring the importance of targeted epidemiological surveys on the knowledge of the disease.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"115 ","pages":"Article 102260"},"PeriodicalIF":2.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leading report regarding the molecular epidemiology of Taenia hydatigena from Pakistan and global overview of the genetic diversity and population structure of the parasite: Correspondence 关于巴基斯坦水蚤分子流行病学的主要报告以及寄生虫遗传多样性和种群结构的全球概览：通讯。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-19 DOI: 10.1016/j.cimid.2024.102259

Hinpetch Daungsupawong , Viroj Wiwanitkit

引用次数: 0

The antimicrobial resistance profile in poultry of Central and Southern India is evolving with distinct features 印度中部和南部地区家禽的抗菌药耐药性概况正在发生变化，并呈现出明显的特征。

IF 2 3区农林科学

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2024-10-16 DOI: 10.1016/j.cimid.2024.102255

Ajmal Aseem, Prarthi Sagar, Nerellapally Samyukthakumar Reddy, Shobi Veleri

{"title":"The antimicrobial resistance profile in poultry of Central and Southern India is evolving with distinct features","authors":"Ajmal Aseem, Prarthi Sagar, Nerellapally Samyukthakumar Reddy, Shobi Veleri","doi":"10.1016/j.cimid.2024.102255","DOIUrl":"10.1016/j.cimid.2024.102255","url":null,"abstract":"<div><div>Antimicrobial resistance (AMR) is fast emerging and is depleting antibiotics repertoire. Poultry is a major source for AMR because focus to enhance its production by modern practices widely uses antibiotics. India and China are major producers of meat and have hotspots of AMR. The Central and Southern India were predicted as emerging hotspots for AMR in poultry but no data available to substantiate it. To this end, we collected chicken feces from poultry farms in these regions and isolated genomic DNA. Further, shotgun whole genome sequencing was performed for metagenomics analysis. For the first time, we report the AMR gene profiles in poultry from Kerala and Telangana. The samples exhibited a higher prevalence of gram-negative and anaerobic species. The high priority pathogens in India were detected, like <em>E.coli, Clostridium perfringens</em>, <em>Klebsiella pneumonia Staphylococcus aureus, Enterococcous faecalis, Pseudomonas aeruginosa, Bacteriodes fragiles</em>. Conspicuously, the Southern India had the highest abundance of AMR genes than the Central India. <em>E.coli</em> was significantly more prevalent in the southernmost zone of India than in other sites. Our data had many common AMR profile features of the European Union (EU) poultry farms but lacked <em>mcr-1</em>, which was a lately emerged AMR gene in <em>E.coli.</em> Our data revealed the extent of AMR gene evolved in the Central and Southern India. It is comparable to the EU data but severity is lesser than in the EU.</div></div>","PeriodicalId":50999,"journal":{"name":"Comparative Immunology Microbiology and Infectious Diseases","volume":"114 ","pages":"Article 102255"},"PeriodicalIF":2.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0