{"title":"Assessing salivary innate immune responses in adolescents with dentofacial abnormalities and central precocious puberty","authors":"K. A. Kolesnik, A. M. Belousova","doi":"10.33925/1683-3031-2024-717","DOIUrl":"https://doi.org/10.33925/1683-3031-2024-717","url":null,"abstract":"Relevance. Central precocious puberty (CPP), characterized by a high incidence of 60% among endocrinopathies during puberty, significantly influences dentofacial development and the local immune defense mechanisms in adolescents. However, the impact on saliva's innate immune function remains underexplored.This study aims to evaluate the innate immune function of saliva in individuals with CPP coexisting with dentofacial abnormalities.Materials and methods. An analysis of saliva biochemical markers was conducted on 59 adolescents diagnosed with CPP and dentofacial abnormalities, alongside a control group of 21 age-matched individuals with dentofacial abnormalities but without systemic conditions, aged 13-18 years. The evaluation focused on lysozyme and urease levels, dysbiosis markers indicating oral microbiota status, malondialdehyde (MDA) levels, and catalase activity to gauge the balance between pro-oxidant and antioxidant systems, alongside proteolytic enzyme elastase activity.Results. Adolescents with combined CPP and dentofacial abnormalities exhibited weakened antioxidant and antibacterial defenses, evidenced by decreased catalase activity (0.105 ± 0.020 mkat/l, p < 0.001) and lysozyme levels (54.7 ± 3.2 U/l, p < 0.02), against a backdrop of increased lipoperoxidation and microbial contamination (MDA levels at 0.48 ± 0.11 μmol/l, p < 0.05, urease levels at 0.713 ± 0.015 μkat/l, p < 0.01), and heightened inflammation (elastase activity up to 2.71 ± 0.12 μkat/l, p < 0.01).Conclusion. The diminished innate immune function in saliva necessitates the development of strategies to enhance it, serving as a preventive measure against gingivitis in patients with CPP.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"56 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Y. Oborotistov, A. A. Fokina, D. N. Vracheva, S. N. Ermoljev, O. Yanushevich, L. Persin, A. G. Sedoykin
{"title":"Functional and morphological evaluation of the dentofacial system in patients with distal occlusion using ultrasonic diagnostic methods","authors":"N. Y. Oborotistov, A. A. Fokina, D. N. Vracheva, S. N. Ermoljev, O. Yanushevich, L. Persin, A. G. Sedoykin","doi":"10.33925/1683-3031-2024-713","DOIUrl":"https://doi.org/10.33925/1683-3031-2024-713","url":null,"abstract":"Relevance. The integrity of the dentofacial system, significantly influenced by the functional condition of the masseter muscles (MM) and the morphological alterations in the alveolar bone, plays a crucial role in the outcome and duration of orthodontic treatment for distal occlusion. Ultrasonic diagnostic methods, due to their physiological compatibility, high information content, and ergonomic design, offer a preferable alternative for assessing and tracking these changes throughout orthodontic treatment.Materials and methods. This study included 55 individuals of both genders, aged 9-12, with either normal occlusions (NO) or distal occlusions (DO). Ultrasound examinations of the MM at rest and during maximum voluntary teeth clenching were conducted to evaluate MM thickness and echotexture. Ultrasonic densitometry measurements were conducted through the assessment of ultrasound transit velocity (UTV). This was carried out across the interalveolar bone with probes positioned on the buccal and oral sides between two neighboring teeth roots.Results. The findings indicated that DO patients had a notably thicker MM compared to their NO counterparts. Variations in MM echotexture were observed, with differences in the anechogenic and hyper echogenic zones. Recorded UTV values illustrated that the highest alveolar bone density in DO subjects was predominantly in the frontal regions of both jaws on the left side, whereas the lowest density was observed in the right lateral regions. For NO subjects, the highest density values were identified in the frontal region of the mandibular bone, with the lowest in the maxillary bone's lateral regions on both sides.Conclusion. The application of advanced ultrasonic diagnostic methods in this study facilitated a detailed functional and morphological analysis of the MM, as well as an evaluation of alveolar bone density in individuals with both distal and normal occlusions. The development of ultrasonic alveolar bone density chart from this research provides a valuable addition to dental examination protocols for patients undergoing orthodontic treatment.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"8 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. M. Scherbakova, O. Admakin, N. S. Morozova, I. A. Kozlitina, A. A. Saushkina
{"title":"Oral health of children and adolescents with type 1 diabetes mellitus: a literature review","authors":"M. M. Scherbakova, O. Admakin, N. S. Morozova, I. A. Kozlitina, A. A. Saushkina","doi":"10.33925/1683-3031-2024-687","DOIUrl":"https://doi.org/10.33925/1683-3031-2024-687","url":null,"abstract":"Relevance. Type 1 diabetes mellitus is a prevalent chronic metabolic autoimmune condition among children and adolescents. The compromised metabolic control associated with this endocrinopathy elevates the risk of various complications, including oral diseases. Establishing an interdisciplinary approach to enhance oral care for young patients with type 1 diabetes mellitus is crucial in contemporary dentistry.Objective. To synthesize information regarding the relationship between type 1 diabetes mellitus and oral health in children and adolescents.Materials and methods. The search strategy involved both electronic and manual searches, querying key databases like PubMed, eLibrary, MEDLINE, and Embase using specific keywords related to the subject. Additionally, a manual search was conducted in the references of relevant articles.Results. The literature review identified the most frequently occurring oral diseases in children and adolescents with type 1 diabetes mellitus. It highlighted key biomarkers for monitoring oral health in these patients. The review uncovered major gaps in understanding the oral manifestations of type 1 diabetes mellitus.Conclusion. Exploring the links between pathogenesis of type 1 diabetes mellitus in young populations and their oral health is pivotal for pediatric dentistry and endocrinology. Addressing this issue could lead to more effective treatment strategies, enhance preventive measures, and improve the diagnostic accuracy of oral diseases. Discrepancies among study findings underscores the imperative for ongoing research and substantiates the value of an interdisciplinary approach in investigating the dental manifestations associated with this endocrine disorder.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"37 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140740973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Modina, E. V. Mamaeva, M. V. Moseeva, L. R. Salimova, N. A. Musina, V. S. Lyamina
{"title":"Orodental Manifestations of Noonan Syndrome: a Clinical Case Study","authors":"T. Modina, E. V. Mamaeva, M. V. Moseeva, L. R. Salimova, N. A. Musina, V. S. Lyamina","doi":"10.33925/1683-3031-2024-695","DOIUrl":"https://doi.org/10.33925/1683-3031-2024-695","url":null,"abstract":"Relevance. Mutations in the PTPN11 gene, a hallmark of Noonan syndrome, disrupt the normal development of connective tissue structure, resulting in a range of manifestations, including orodental abnormalities.Clinical case description. This article presents a medical record of a 14-year-old patient diagnosed with Noonan syndrome who sought medical assistance due to exacerbated chronic generalized periodontitis. The authors implemented a two-stage treatment approach, resulting in satisfactory outcomes. They identified concurrent orodental symptoms and conducted analyses of orthopantomography and bone densitometry for both jaws. A personalized treatment schedule was devised, emphasizing the necessity for the patient's chronic periodontitis to be in a state of remission and the utilization of sedation for effective management. Following the implementation of a planned series of therapeutic interventions during the remission stage, including professional oral care, teeth splinting with orthodontic retainers, nonsurgical root debridement, and mandibular labial frenuloplasty, quarterly follow-up assessments were chosen as the preferred monitoring method.Conclusion. Patients with hereditary pathologies, such as Noonan syndrome, often exhibit significant orodental manifestations. Addressing such conditions necessitates specific treatment techniques that integrate a comprehensive approach, timely diagnostics, and collaboration between general practitioners and dentists. Given the unique needs of these patients, it is essential to develop personalized treatment protocols tailored to their individual requirements, including the duration and efficacy of chosen treatments, as well as considerations for anesthesia or sedation care.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"17 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140412790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Findings of an orthodontic and osteopathic diagnostic of individuals with an asymmetric narrowing of maxilla","authors":"M. Vasilyeva, G. S. Perevezentsev, T. Kosyreva","doi":"10.33925/1683-3031-2023-690","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-690","url":null,"abstract":"Relevance. Postural disorders and their connection to dentofacial abnormalities represent a prominent subject in modern medicine, establishing a new diagnostic standard within the emerging fields of orthodontic and osteopathic diagnostic techniques.Objective. Establish a correlation between asymmetric narrowing of maxilla and postural disorders in children and teens aged 6 to 15 years. Substantiate the necessity for a combined approach involving both orthodontic and osteopathic diagnostics in this age group, aiming to develop a comprehensive treatment algorithm.Materials and methods. Orthodontists and an osteopathic physician conducted diagnostic procedures for 320 subjects. Verification methods included standardized questionnaires for orthodontics and osteopathy, digital photography, radiological analysis using cone beam computer tomography (CBCT) of the head, electromyography (EMG), and computer-aided optical postural topography with the DIERS formetric 4D motion system.Results. Among the 320 subjects examined, the study revealed that 65% presented with an asymmetric narrowing of maxilla. Digital photography illustrated deviations from the norm in the total width of the maxilla for all subjects, a critical factor influencing proper tongue posture, swallowing, and breathing patterns. Facial asymmetry and temporomandibular disorders (TMD) were prevalent among the majority of patients, with a reported mandibular deviation observed in 100% of cases. Based on CBCT data, the transverse dimension of the asymmetrically narrow maxilla, relative to the mid-sagittal axis, was found to be reduced, along with a concomitant displacement of the greater wings of the sphenoid bone. The measured electric activity of masticatory and temporal muscles supported the diagnosis of asymmetric muscular dysfunction. Additionally, irregularities in the sphenobasilar synchondrosis (SBS) were identified. Moreover, patients with asymmetric maxillary narrowing exhibited static and dynamic imbalance in the body, along with disorders of body posture and foot profile. These observations were made through visual assessment, manual testing, and the DIERS formetric 4D motion optical posture topography system.Conclusion. Asymmetric maxillary narrowing strongly correlated with posture disorders, static and dynamic imbalances in the body, and dysfunctions in primary activities such as chewing, swallowing, breathing, and gait patterns. To achieve a predictable outcome without complications, it is recommended to pursue both orthodontic and osteopathic treatments for cases involving an asymmetric narrowing of maxilla.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"187 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140481151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Malanova, N. S. Morozova, V. M. Grinin, O. Admakin, A. Maltseva, E. T. Savenko
{"title":"The prevalence and severity of malocclusion in foster home children","authors":"O. Malanova, N. S. Morozova, V. M. Grinin, O. Admakin, A. Maltseva, E. T. Savenko","doi":"10.33925/1683-3031-2023-682","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-682","url":null,"abstract":"Relevance. Malocclusions in children present a pressing concern in the field of dentistry. Timely diagnostics and treatment of these conditions are crucial for children aged 6 to 18, residing in foster homes, where incidence tend to be higher compared to children raised in family settings. This heightened incidence is often attributed to the lack of timely examinations by pediatric dentist or orthodontists. Such examinations could have potentially prevented the development of malocclusions or facilitated the administration of appropriate orthodontic treatments.Materials and methods. The study included 200 children aged 6 to 18, categorized into two groups: 100 children residing in foster homes or orphanages and 100 living with families (control group). Various malocclusions were identified using the Dental Aesthetic Index (DAI) dental aesthetic index and Angle's classification.Results. Malocclusions were identified in 89.3% of the children from foster home, compared to 66.6% of children from family households. The most prevalent types of malocclusions observed were crowding of front teeth and incisor cross-bite. The DAI dental aesthetic index was higher in children from foster home (DAI = 30.4) than in those from family (DAI = 27.8). Additionally, it was observed that none of the children from foster homes had undergone orthodontic treatment, in contrast to the children in the control group.Conclusion. The study underscores the significance of diagnosing and treating malocclusions in children, with particular emphasis on those residing in foster homes. The results highlight the necessity of implementing effective methods to prevent and address malocclusions in such environments, aiming to enhance the dental health of the children.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"38 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139598258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Makedonova, V. V. Shkarin, O. S. Emelyanova, T. V. Chizhikova, I. V. Venskel, L. A. Devyatchenko
{"title":"Screening as a stage in the prevention of oral mucosal diseases in patients undergoing chemotherapy for malignant growths","authors":"Y. Makedonova, V. V. Shkarin, O. S. Emelyanova, T. V. Chizhikova, I. V. Venskel, L. A. Devyatchenko","doi":"10.33925/1683-3031-2023-689","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-689","url":null,"abstract":"Relevance. The incidence of malignant growths in the maxillofacial area has consistently increased over the years. Chemotherapy stands out as one of the most effective treatments for cancerous tumors. Chemotherapeutic drugs possess the capability to either inhibit the proliferation of malignant cells or cause damage to them. However, while acting on abnormal cells, cytostatic drugs also impact actively dividing cells in normal tissues, including the mucous membranes in the oral cavity. As a result, various complications are observed in every patient undergoing treatment for malignant neoplasms (MN), particularly chemotherapy (CT). The nature and severity of side effects undergo changes based on the specific drugs and cytostatic treatment regimen employed. Adverse reactions and side effects inherent to each drug category manifest at different points throughout a chemotherapy course and its aftermath. Oral mucosal (OM) complications, such as oral mucositis, may ensue as a consequence of CT side effects.Materials and methods. In order to assess the effectiveness of screening for OM disorders arising as side effects of chemotherapy, a study involving 37 patients undergoing chemotherapy for an underlying condition was conducted. The screening study comprised two stages: Stage I involved a quality-of-life assessment utilizing questionnaires developed by the authors, while Stage II entailed a clinical examination of the oral mucosa. The obtained data were subjected to statistical analysis methods. Variation statistics were employed to assess the likelihood of data errors.Results. Comprehensive OM diagnostics in patients undergoing chemotherapy for an underlying oncology condition enable the early identification of oral mucosal diseases and the prevention of complications. It is recommended to conduct a thorough clinical examination and employ toluidine blue staining during each follow-up visit. Any observed clinical or stained tissue changes, the emergence of new erythematous lesions, erosions, or ulcers may serve as indicators of malignant transformation.Conclusion. It is advisable to incorporate screening diagnostics into each patient's dental visit to proactively prevent the onset of various pathological conditions.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"36 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139599443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of periodontal diseases in children under 6 years old in the Republic of Tatarstan: impact of age and family structure","authors":"M. Khadyeva, S. L. Blashkova, A. Galiullin","doi":"10.33925/1683-3031-2023-659","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-659","url":null,"abstract":"Relevance. This article addresses the prevalence of periodontal diseases in infants and preschool-aged children, considering factors such as the child's age and family structure within the region of the Republic of Tatarstan. Periodontal diseases, in conjunction with dental caries and dental abnormalities, represent the most frequently observed oral health conditions among children and adolescents.Materials and methods. The research involved 2429 families and 2556 preschool-aged children representing diverse family structures within Kazan, Arsk, and Pestrechinsky districts in the Republic of Tatarstan. During the survey, five primary family classifications emerged: complete, incomplete, extended, reconstituted, and foster families. The research methodology involved conducting interviews with parents, close relatives, or guardians, coupled with comprehensive examinations of the children, documenting both systemic disease and general health information using specifically tailored charts. Data analysis included determining mean values (M), mean error of the score (m), and Student's t-test criterion (t). Significance among group disparities was established at a probability of error less than 5% (p < 0.05). The gathered data underwent interpretation, considering both family structure and the spectrum of periodontal diseases.Results. Periodontal diseases were found to affect children from foster and incomplete families most significantly, with prevalence rates exceeding 90% in certain age groups. Children from complete and extended families exhibited lower prevalence rates of periodontal diseases, at 9.8% and 22.2%, respectively. Notably, within all age brackets, the highest occurrence of periodontal diseases was observed among children aged 4.6-6 years, constituting 57.0% of cases. Infants under one year old displayed the lowest susceptibility, with only 16.3% affected. Upon analyzing disease prevalence among children in the Republic of Tatarstan, a significant disparity emerged: children residing in rural areas demonstrated a higher susceptibility to periodontal diseases in comparison to their urban counterparts.Conclusion. The findings reveal a clear correlation between a child's family structure and the occurrence of periodontal diseases. Establishing the family structure and implementing tailored preventive measures specific to periodontal diseases, while considering both the child's family structure and age, plays a significant role in averting the onset and progression of this condition.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139607643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Lukashevich, I. Gorbunova, G. Skripkina, L. V. Lukashevich
{"title":"Investigating the impact of kallikrein 4 gene polymorphism on caries severity and development in divers age groups of pregnant women during caries prevention","authors":"I. Lukashevich, I. Gorbunova, G. Skripkina, L. V. Lukashevich","doi":"10.33925/1683-3031-2023-639","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-639","url":null,"abstract":"Relevance. The progression of caries during pregnancy is significantly influenced by the resistance of dental tissues against demineralization. The degree of resistance in dental enamel is influenced by its genetic determinants, encompassing structural and morphological properties. The kallikrein 4 (KLK4) gene plays a pivotal role as a primary enzyme in dental enamel formation. Consequently, evaluating the effectiveness of various preventive measures on dental enamel necessitates consideration of KLK4 gene mutations.Material and methods. An examination was conducted on a cohort of 322 pregnant women. Key indices assessed included OHI-S, DMF, DMFs, ∆DMF, and ∆DMFs. Oral fluid analysis encompassed parameters such as Ca, P, Ca/P-molar ratio, рН, Ca2+, pK+, pNa+. The sediment of oral fluid was examined for ∆рН and ∆Ca. DNA sample was isolated from venous blood obtained from the participants.Results. The G/G polymorphism of the KLK4 gene at positions G2664153A and G2142А did not exhibit a statistically significant association with an increase in the ∆DMFs index during caries prevention, a finding consistent across both discussed tools for exogenous caries prevention in this study. In case of heterozygous KLK4 G/A polymorphism with the dominant G allele, the application of Enamel Sealing Liquid showed a tendency towards higher ∆DMF and ∆DMFs indices over a 12-month follow-up period. When pregnant patients with heterozygous dominant G allele mutations were treated with the triple-component calcium-fluorine-phosphate-containing gel, there were no observed elevations in these indices. The amplified production of KLK4 A/A polymorphism was associated with a statistically significant rise in ∆DMF and ∆DMFs indices, accompanied by alterations in certain oral fluid parameters. These changes included reduced active calcium levels and Ca/P molar ratio, along with elevated levels of phosphates and electrolytes. Enhanced demineralizing activity was observed in the oral fluid sediment.Conclusion. The effectiveness of caries prevention tools during pregnancy is contingent upon the genotypic diversity of KLK4 gene polymorphism at the G2664153A and G2142А mutation points.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":"71 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139606445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. R. Minnakhmetova, O. Z. Topolnitsky, O. A. Solodovnik, I. V. Tikhonova
{"title":"Comprehensive management of Pindborg tumor in childhood: a case report","authors":"D. R. Minnakhmetova, O. Z. Topolnitsky, O. A. Solodovnik, I. V. Tikhonova","doi":"10.33925/1683-3031-2023-710","DOIUrl":"https://doi.org/10.33925/1683-3031-2023-710","url":null,"abstract":"Relevance. The calcifying epithelial odontogenic tumor, also known as Pindborg tumor, is a locally aggressive neoplasm characterized by strands and medullary formations of flat and clear cells, often accompanied by spherical calcifications and amyloid-stained hyaline deposits. The Pindborg tumor is rare, representing less than 1% of odontogenic tumors, and typically manifests in individuals aged 20 to 60 years. However, there is a growing incidence of neoplasms of diverse origins in childhood. This article presents a clinical case detailing the comprehensive multi-stage treatment of a pediatric patient with a Pindborg tumor, facilitating complete rehabilitation before reaching adulthood.Clinical case description. This article presents a clinical case detailing the comprehensive management of a patient with a Pindborg tumor. The individual initially sought treatment at the Department of Pediatric Maxillofacial Surgery of A.I. Evdokimov Moscow State Medical and Dental University in 2020, undergoing complete combined treatment until November 2023. Full rehabilitation was successfully achieved by the time of adulthood through a series of four consecutive surgeries, including dental implantation, followed by prosthetics utilizing a non-removable orthopedic structure in the final stage.Conclusion. Initiating comprehensive rehabilitation at an early stage, including dental implantation before reaching adulthood, facilitates complete social adaptation in society and contributes to the patient's harmonious development.","PeriodicalId":509861,"journal":{"name":"Pediatric dentistry and dental prophylaxis","volume":" March","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139617867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}