{"title":"L’évolution donne souvent la solution","authors":"Sarah Barhdaoui , Audrey Lupo , Mathilde Sibony","doi":"10.1016/j.annpat.2024.07.003","DOIUrl":"10.1016/j.annpat.2024.07.003","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"45 3","pages":"Pages 261-265"},"PeriodicalIF":0.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid Laurent-Bellue , Margot Dupeux , Loris Guichard , Suzanne Chartier , Alice Gautier , Anna Mensa , Jean-Yves Scoazec , Sophie Prévot , Catherine Guettier , Sophie Ferlicot
{"title":"Nouvelles approches pédagogiques pour l’enseignement de la pathologie en premier et deuxième cycles des études médicales, l’expérience de l’université Paris-Saclay","authors":"Astrid Laurent-Bellue , Margot Dupeux , Loris Guichard , Suzanne Chartier , Alice Gautier , Anna Mensa , Jean-Yves Scoazec , Sophie Prévot , Catherine Guettier , Sophie Ferlicot","doi":"10.1016/j.annpat.2024.12.004","DOIUrl":"10.1016/j.annpat.2024.12.004","url":null,"abstract":"<div><h3>Introduction</h3><div>L’enseignement de la pathologie est essentiel et précoce dans le cursus des études médicales. Il est classiquement théorique, souvent accompagné d’enseignements dirigés au cours du premier cycle. L’accès aux stages de pathologie pour les étudiants de deuxième cycle n’est pas toujours possible. Après la réforme du premier cycle, l’augmentation de la taille des promotions d’étudiants a imposé une réorganisation de l’enseignement de pathologie de la faculté de médecine de l’université Paris-Saclay. Notre objectif était d’évaluer les performances des étudiants et la satisfaction des étudiants et des enseignants après ces changements.</div></div><div><h3>Matériels et méthodes</h3><div>Nous avons comparé les résultats des étudiants au contrôle continu et à l’examen théorique 3 années avant la réorganisation pédagogique et 2 années après ; nous avons évalué la satisfaction des étudiants et des enseignants à l’aide de questionnaires.</div></div><div><h3>Résultats</h3><div>La taille des promotions d’étudiants de troisième année de médecine a augmenté progressivement de 77 % après la réforme. Les séances d’enseignements dirigés se déroulent désormais sous forme de diaporamas interactifs en amphithéâtre. Les résultats au contrôle continu sont restés stables (<em>p</em> <!-->=<!--> <!-->0,62), les résultats à l’examen théorique se sont améliorés (<em>p</em> <!-->=<!--> <!-->0,02) depuis le changement de l’organisation de l’enseignement. Les étudiants et les enseignants sont satisfaits des diaporamas interactifs ; les étudiants sont demandeurs de capsules vidéo pour illustrer les lames numérisées.</div></div><div><h3>Discussion</h3><div>L’enseignement de la pathologie a beaucoup évolué depuis quelques années pour s’adapter aux différentes réformes et répondre aux attentes des étudiants. De nouveaux outils pédagogiques permettent d’accompagner ces changements.</div></div><div><h3>Introduction</h3><div>Teaching pathology is an essential and early part of the medical curriculum. It is classically theoretical, often accompanied by tutorials. Access to pathology internships for students is not always possible. Following the reform of the undergraduate curriculum, the increase in the size of the student classes has necessitated a reorganization of pathology teaching at the University of Paris-Saclay faculty of medicine. Our goal was to evaluate student performance and student and teacher satisfaction after these changes.</div></div><div><h3>Materials and methods</h3><div>We compared results in continuous assessment and theory exams 3 years before the pedagogical reorganization and 2 years afterwards; we assessed student and teacher satisfaction using questionnaires.</div></div><div><h3>Results</h3><div>The size of third-year medical student classes gradually increased by 77% after the reform. Tutorials are now given in the form of interactive slide shows in amphitheatres. Continuous assessment results have remained stable (<em>p</em> ","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"45 3","pages":"Pages 214-223"},"PeriodicalIF":0.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hétérotopie intestinale vulvaire chez une fille de 12 ans","authors":"Sara El Ghaffouli , Lamiaa Rouas","doi":"10.1016/j.annpat.2024.12.002","DOIUrl":"10.1016/j.annpat.2024.12.002","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"45 3","pages":"Pages 280-281"},"PeriodicalIF":0.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Cysts in pathology: Between biological mysteries and diagnostic challenges].","authors":"Mohamed Amine Bani, Magali Lacroix-Triki","doi":"10.1016/j.annpat.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.annpat.2025.02.006","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Breast adenomyoepithelioma: About a case and review of the literature].","authors":"Louis Vaquier, Magali Lacroix-Triki","doi":"10.1016/j.annpat.2025.02.014","DOIUrl":"https://doi.org/10.1016/j.annpat.2025.02.014","url":null,"abstract":"<p><p>Adenomyoepithelioma (AME) is a rare primary breast tumor characterized by a mixed proliferation of epithelial and myoepithelial cells. This tumor can display heterogeneous, often nonspecific, imaging features. A definitive diagnosis of AME requires a biopsy with histopathological examination to guide therapeutic management. However, the rarity of this lesion, the type of sampling, and its polymorphic appearance can make diagnosis particularly challenging. Differential diagnoses are extensive, encompassing both benign and malignant lesions. We present herein the case of a 76-year-old female patient along with a review of the literature on breast AME.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Apocrine lesions of the breast].","authors":"Gaëtan MacGrogan","doi":"10.1016/j.annpat.2025.03.001","DOIUrl":"https://doi.org/10.1016/j.annpat.2025.03.001","url":null,"abstract":"<p><p>Apocrine breast lesions encompass a spectrum of histopathological abnormalities, ranging from benign apocrine metaplasia to invasive apocrine carcinomas. Their defining feature lies in cells with abundant eosinophilic cytoplasm and round nuclei with prominent nucleoli. These cells strongly express the androgen receptor while lacking estrogen receptor-alpha and progesterone receptor expression. Benign lesions, frequently associated with mammary cysts or papillomas, lack nuclear and architectural atypia. In contrast, atypical apocrine lesions exhibit significant nuclear and structural abnormalities, posing diagnostic challenges when distinguishing them from apocrine ductal or lobular carcinoma in situ. Diagnosis relies on the extent of atypia and the presence of tumor necrosis. Invasive apocrine carcinomas are rare, accounting for less than 1% of all breast cancers, and predominantly occur in postmenopausal women. Histologically, they are often grade 1 or 2 tumors. Approximately 50% exhibit HER2 amplification and overexpression. Immunohistochemically, they are characterized by positivity for FOXA1 and GATA3, and negativity for FOXC1 and SOX10, and variable expression of TRPS1. These carcinomas belong to the molecular apocrine carcinoma family, which includes HER2-enriched tumors driven by HER2 addiction and androgen receptor-positive luminal tumors, a subtype of triple-negative breast cancers. The latter are defined by androgen receptor pathway activation and are frequently associated with PI3K pathway alterations and cell cycle dysregulation, suggesting potential therapeutic targets.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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