West Kazakhstan Medical Journal最新文献

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New Horizons in Treatment of Knee Osteoarthritis: A Brief Look-up at Emerging Approaches 膝骨关节炎治疗的新视野:新方法简介
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14677
Afsaneh Zare, Aida Iraji, S. Zare, O. koohi-Hosseinabadi, Fateme Bagheri, Romina Tanideh, Nader Tanideh
{"title":"New Horizons in Treatment of Knee Osteoarthritis: A Brief Look-up at Emerging Approaches","authors":"Afsaneh Zare, Aida Iraji, S. Zare, O. koohi-Hosseinabadi, Fateme Bagheri, Romina Tanideh, Nader Tanideh","doi":"10.18502/wkmj.v65i4.14677","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14677","url":null,"abstract":"Knee osteoarthritis (OA) is a chronic and prevalent musculoskeletal condition that is the underlying cause of disability in most patients worldwide. Even though the pathophysiology of KOA has not yet been fully understood and includes a wide range of risk factors, current therapeutic options are temporarily palliative rather than curative. In recent years, new strategies have focused on the curative agents. As part of this review, we highlight the latest treatment approaches for KOA.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subclinical Hypothyroidism and Functional Hemodynamics of the Heart 亚临床甲状腺功能减退症与心脏功能性血液动力学
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14685
Raisa A. Aringazina, Nurgul Abenova, Sajad Ahmad Bhat
{"title":"Subclinical Hypothyroidism and Functional Hemodynamics of the Heart","authors":"Raisa A. Aringazina, Nurgul Abenova, Sajad Ahmad Bhat","doi":"10.18502/wkmj.v65i4.14685","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14685","url":null,"abstract":"Subclinical hyperthyroidism (SHyper), a laboratory decrease in thyroid-stimulating hormone levels with peripheral thyroid hormone levels within the reference interval, is considered a medical condition, especially its impact on cardiac hemodynamics among young women. To determine the effects of subclinical thyroid dysfunction on hemodynamics in young women. clinical observation included two groups of women: (1) the main group consisted of 30 patients with subclinical hyperthyroidism, which was examined at the Family Medicine Clinic of the West Kazakhstan Marat Ospanov Medical University (Aktobe, Kazakhstan) and (2) the control group consisted of 30 practically healthy women. The groups were comparable in age (30–42), mean age 36.2±7.0 years. Blood pressure (BP) was measured, heart rate (HR) was counted, and thyroid hormones were determined. in the examined patients, clinical symptoms of pathology were not observed; laboratory tests determined a decrease in thyroid-stimulating hormone (TSH) in the main group of patients to 2.48±0.23 mIU/L in comparison with the control group 3.65±1.3 mIU/L, which was significant (p0.05) increase in blood pressure SBP/DBP from 122.34±2.7/78.3±2.7 to 127.8±3.1/83.2±2.1 mmHg and HR from 77.7±1.9 to 82.2±2.6 in 1 minute. A significant (r2 =0.482) interaction was determined between TSH -0.236 mIU/L and HP +20.3 in 1 minute, this could be a predictor of an increase in heart rate greater than the reference value (60–80 per minute), and an increased heart rate is considered a predictor of an increase in blood pressure. Subclinical hyperthyroidism may produce a significant laboratory decrease in TSH, without significant clinical symptoms of increased blood pressure. In conclusion, current observational experience suggests that small decreases in laboratory values of thyroid-stimulating hormone may affect blood pressure and heart rate.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"41 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139167135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Interventions on Informal Caregivers of Older Adults: A Scientific Mini Review 干预措施对老年人非正式照顾者的影响:科学微型综述
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14678
A. Zhylkybekova, Gulbakit K. Koshmaganbetova, Andrej M. Grjibovski, N. Glushkova
{"title":"Effect of Interventions on Informal Caregivers of Older Adults: A Scientific Mini Review","authors":"A. Zhylkybekova, Gulbakit K. Koshmaganbetova, Andrej M. Grjibovski, N. Glushkova","doi":"10.18502/wkmj.v65i4.14678","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14678","url":null,"abstract":"The growing number of older adults with long-term health issues has led to more family members becoming informal caregivers. These caregivers play a crucial role in providing care to their elderly loved ones. However, this caregiving can be physically and emotionally demanding, affecting the caregivers’ own well-being. This scientific mini-review examines various ways, known as “interventions,” that can help ease the challenges faced by informal caregivers and improve their quality of life. These interventions can include things like training programs, support groups, or using technology to assist caregivers. To get the most up-to-date information, we looked at the recent systematic reviews and studies published in the last 5 years. We searched for this information in three widely recognized electronic databases: PubMed, Web of Science, and Scopus with full text. These interventions show promise in making life easier for informal caregivers and improving their quality of life. This mini review intends to offer insights into how these interventions can be beneficial, serving as a resource for healthcare professionals, policymakers, and researchers working to enhance the well-being of both caregivers and the elderly individuals they care for.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"41 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embracing Change: The Transition of the West Kazakhstan Medical Journal to English 拥抱变化:西哈萨克斯坦医学杂志向英文版的过渡
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14676
A. Tamadon, Asset A. Kaliyev, Nadiar M. Mussin
{"title":"Embracing Change: The Transition of the West Kazakhstan Medical Journal to English","authors":"A. Tamadon, Asset A. Kaliyev, Nadiar M. Mussin","doi":"10.18502/wkmj.v65i4.14676","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14676","url":null,"abstract":"For nearly two decades, the West Kazakhstan Medical Journal (WKMJ) has been a cornerstone of medical knowledge and research in the West Kazakhstan region, serving as a vital platform for local and regional healthcare communities. In a strategic move, the journal is transitioning to the English language, aligning itself with the global discourse in medical science. This transition aims to enhance accessibility, visibility, and impact, fostering international collaborations and contributing valuable insights to the broader medical community. The metamorphosis signifies a commitment to global integration without compromising the journal’s unwavering commitment to quality, ethical publishing, and rigorous peer review. The transformation invites researchers, practitioners, and institutions worldwide to participate in this journey, elevating the exchange of medical knowledge on a global scale","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"50 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Four Elements in Low-Vision Rehabilitation Service 低视力康复服务的四个要素
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14679
Suresh Subramaniam
{"title":"The Four Elements in Low-Vision Rehabilitation Service","authors":"Suresh Subramaniam","doi":"10.18502/wkmj.v65i4.14679","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14679","url":null,"abstract":"This article addresses the critical issue of low-vision rehabilitation (LVR) services, focusing on the challenges faced by visually impaired patients, particularly those with central visual field limitations and visual acuity of 3/60 or worse in the better eye. Glaucoma, a chronic progressive optic neuropathy, poses a significant threat to vision and quality of life. Despite the absence of a definitive cure, various treatment modalities aim to control and slow down its progression. However, the impact of glaucoma-related structural and functional vision loss on patients’ quality of life is profound. Visual rehabilitation plays a pivotal role in guiding patient-centered therapeutic decisions, yet it remains underutilized for glaucoma patients. Understanding the available LVR is crucial in developing new tools and approaches. This article provides an overview of LVR options for visually impaired individuals and emphasizes the importance of comprehensively assessing and addressing their needs, both in terms of visual function and overall well-being.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ureterocele in Combination with Urolithiasis in a Pregnant Woman 一名孕妇的输尿管鞘膜积液合并泌尿系结石
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14686
Gafour Khairli, U. Zhanbyrbekuly, Alexey Suchshenko, Almas Muralovich Kazhitaev, Ravshan Zulfugarogly Alnagiev, Orkhan Alyshanogly Ismailov, Abylaikhan Zhakiyauly Baigozha
{"title":"Ureterocele in Combination with Urolithiasis in a Pregnant Woman","authors":"Gafour Khairli, U. Zhanbyrbekuly, Alexey Suchshenko, Almas Muralovich Kazhitaev, Ravshan Zulfugarogly Alnagiev, Orkhan Alyshanogly Ismailov, Abylaikhan Zhakiyauly Baigozha","doi":"10.18502/wkmj.v65i4.14686","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14686","url":null,"abstract":"This article is devoted to the description of the clinical picture, methods of laboratory and instrumental diagnostics, the choice of surgical treatment and postoperative rehabilitation of a patient with a rare urological pathology - ureterocele in combination with urolithiasis in a pregnant woman.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"18 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139167289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Processed Foods and Gut Health: A Mini Review of Microbiome Responses 加工食品与肠道健康:微生物群反应小回顾
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14683
A. Baspakova, Kulyash R. Zhilisbayeva, Aigerim A. Umbetova, Anara Zh. Abitova
{"title":"Processed Foods and Gut Health: A Mini Review of Microbiome Responses","authors":"A. Baspakova, Kulyash R. Zhilisbayeva, Aigerim A. Umbetova, Anara Zh. Abitova","doi":"10.18502/wkmj.v65i4.14683","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14683","url":null,"abstract":"The present mini review delves into the intricate nexus between processed foods and gut health, with a focused exploration of the dynamic responses exhibited by the gut microbiome. The ubiquity of processed foods in contemporary diets has prompted inquiries into their potential ramifications for human physiological well-being. Given the acknowledged centrality of the gut microbiota in sustaining holistic health, deciphering the nuances of how processed foods impinge upon its constitution and functionality assumes critical significance. By methodically scrutinizing recent empirical investigations, this mini review elucidates the multifaceted manners through which processed foods interface with the complex web of the gut microbial consortium. It meticulously delineates alterations in microbial taxonomic diversity, community richness, and ecological equilibrium, thereby elucidating the putative mechanistic underpinnings driving the possible impact of processed food consumption on physiological equilibrium. Furthermore, the review cogitates upon the broader translational repercussions of these microbiome perturbations, cogently contemplating potential correlations with pathophysiologies encompassing but not limited to inflammation cascades, metabolic perturbations, and immune homeostasis dysregulation. By synthesizing the current compendium of empirical insights, this mini review proffers cogent perspectives into the intricate interplay between processed foods and gut health. It substantiates the exigency for augmented investigative endeavors, whilst advocating for judicious dietary selections that foster resilience and equilibrium within the intricate milieu of the gut microbiome.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"42 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stem Cell- and Stem Cell-Free-Based Therapies: Pros and Cons 干细胞疗法和无干细胞疗法:利与弊
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14684
Halimeh Mobarak, Reza Rahbarghazi, M. Mahdipour
{"title":"Stem Cell- and Stem Cell-Free-Based Therapies: Pros and Cons","authors":"Halimeh Mobarak, Reza Rahbarghazi, M. Mahdipour","doi":"10.18502/wkmj.v65i4.14684","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14684","url":null,"abstract":"The efficiency of stem cell (SC)-based therapies has been proven in numerous animal and human studies. Along with the differentiation into several lineages, it is quite evident that SCs convey significant therapeutic effects in a paracrine manner via releasing various nano-sized extracellular vesicles (EVs) containing cytokines and bioactive factors. Notably, recent trials have stated the lack of stability and durability of the transplanted SCs at the site of injury for long periods, leading to the restrictions of SC in regenerative outcomes. Thus, EVs especially exosomes (Exos) gained much attention for therapeutic purposes and delivery purposes to the injury site. In contrast to whole-SC-based therapies, Exos can be used with fewer side effects. However, it should not be forgotten that both whole-SC- and cell-free-based options possess inherent pros and cons that necessitate being carefully evaluated before application in the clinical setting. Here, the effectiveness and limitations associated with whole-SCand SC-free-based therapies in the clinical setting are briefly discussed.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future Prospects for Assessment of General Movements in Developing Countries 发展中国家一般性迁移评估的未来前景
West Kazakhstan Medical Journal Pub Date : 2023-12-21 DOI: 10.18502/wkmj.v65i4.14681
Zhanna Zhussupova, Dinmukhamed Ayaganov, Gulmira Zharmakhanova, Ayten Mamedbayli
{"title":"Future Prospects for Assessment of General Movements in Developing Countries","authors":"Zhanna Zhussupova, Dinmukhamed Ayaganov, Gulmira Zharmakhanova, Ayten Mamedbayli","doi":"10.18502/wkmj.v65i4.14681","DOIUrl":"https://doi.org/10.18502/wkmj.v65i4.14681","url":null,"abstract":"The well-being of children is crucial for a nation’s demographic, economic, and intellectual prospects. Developing countries face an increasing number of children with disabilities, primarily attributed to congenital developmental defects, neurological disorders, and other health issues. Neurological disorders pose significant challenges to realizing the full potential of children and society. Early intervention is essential for improving functional outcomes in infants with neurological impairments. General Movements (GM) assessment, a predictor of subsequent neurological outcomes, plays a vital role in early detection. However, its widespread implementation in developing countries is limited. This article explores the history of GM assessment, its current state in developing countries, and the potential for mobile applications to revolutionize early assessments and interventions in developing countries.","PeriodicalId":509666,"journal":{"name":"West Kazakhstan Medical Journal","volume":"81 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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