Maria R Farcet, Michael Karbiener, Simone Knotzer, Julia Schwaiger, Thomas R Kreil
{"title":"Omicron Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization by Immunoglobulin Preparations Manufactured From Plasma Collected in the United States and Europe.","authors":"Maria R Farcet, Michael Karbiener, Simone Knotzer, Julia Schwaiger, Thomas R Kreil","doi":"10.1093/infdis/jiac358","DOIUrl":"https://doi.org/10.1093/infdis/jiac358","url":null,"abstract":"<p><p>After >2 years of the coronavirus disease 2019 (COVID-19) pandemic, immunoglobulins (IGs) contain highly potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies, based on the large proportion of United States (US) plasma donors who have gone through COVID-19 or vaccination against the virus. Neutralization of Omicron SARS-CoV-2 by antibodies generated after non-Omicron infection or vaccination has been lower though, raising concerns about the potency of IG against this new virus variant. Also, as plasma collected in the US remains the main source of IG, the neutralization of SARS-CoV-2 for plasma collected elsewhere has been less well studied. Here, we confirm Omicron neutralization by US as well as European Union plasma-derived IG lots.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"1396-1400"},"PeriodicalIF":6.4,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/5f/jiac358.PMC9494343.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40343728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joao Toledo, Michelle M Haby, Ludovic Reveiz, Leopoldo Sosa Leon, Rodrigo Angerami, Sylvain Aldighieri
{"title":"Evidence for Human-to-Human Transmission of Hantavirus: A Systematic Review.","authors":"Joao Toledo, Michelle M Haby, Ludovic Reveiz, Leopoldo Sosa Leon, Rodrigo Angerami, Sylvain Aldighieri","doi":"10.1093/infdis/jiab461","DOIUrl":"https://doi.org/10.1093/infdis/jiab461","url":null,"abstract":"<p><strong>Background: </strong>Hantavirus is known to be transmitted from rodents to humans. However, some reports from Argentina and Chile have claimed that the hantavirus strain Andes virus (ANDV) can cause human-to-human transmission of the disease. The aim of this systematic review was to assess the evidence for human-to-human transmission of hantavirus.</p><p><strong>Methods: </strong>We searched PubMed (inception to 28 February 2021), Cochrane Central, Embase, LILACS and SciELO (inception to 3 July 2020), and other sources. We included studies that assessed whether interpersonal contact with a person with laboratory-confirmed hantavirus infection led to human-to-human transmission. Two reviewers conducted screening, selection, data extraction, and risk of bias assessment.</p><p><strong>Results: </strong>Twenty-two studies met the inclusion criteria. Meta-analysis was not possible due to heterogeneity. With the exception of 1 prospective cohort study of ANDV in Chile with serious risk of bias, evidence from comparative studies (strongest level of evidence available) does not support human-to-human transmission of hantavirus infection. Noncomparative studies with a critical risk of bias suggest that human-to-human transmission of ANDV may be possible.</p><p><strong>Conclusions: </strong>The balance of the evidence does not support the claim of human-to-human transmission of ANDV. Well-designed cohort and case-control studies that control for co-exposure to rodents are needed to inform public health recommendations.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"1362-1371"},"PeriodicalIF":6.4,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39430239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Homelessness and Infectious Diseases: Understanding the Gaps and Defining a Public Health Approach: Introduction.","authors":"Emily Mosites, Laura Hughes, Jay C Butler","doi":"10.1093/infdis/jiac352","DOIUrl":"https://doi.org/10.1093/infdis/jiac352","url":null,"abstract":"","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S301-S303"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Mosites, Emily Eisenberg Lobelo, Laura Hughes, Jay C Butler
{"title":"Public Health and Homelessness: A Framework.","authors":"Emily Mosites, Emily Eisenberg Lobelo, Laura Hughes, Jay C Butler","doi":"10.1093/infdis/jiac353","DOIUrl":"https://doi.org/10.1093/infdis/jiac353","url":null,"abstract":"","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S372-S374"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth M Allen, Betsy Smither, Lindsey Barranco, Jennifer Reynolds, Kelli Bursey, Kristin Mattson, Emily Mosites
{"title":"Communicating Effectively With People Experiencing Homelessness to Prevent Infectious Diseases.","authors":"Elizabeth M Allen, Betsy Smither, Lindsey Barranco, Jennifer Reynolds, Kelli Bursey, Kristin Mattson, Emily Mosites","doi":"10.1093/infdis/jiac336","DOIUrl":"https://doi.org/10.1093/infdis/jiac336","url":null,"abstract":"<p><strong>Background: </strong>People experiencing homelessness (PEH) are disproportionately affected by many infectious diseases, including coronavirus disease 2019 (COVID-19). However, communication efforts during public health emergencies like the COVID-19 pandemic often do not consider the unique needs of PEH. We examined how PEH seek and receive health information and how traditional health communication methods resonate with them.</p><p><strong>Methods: </strong>We conducted in-person focus groups with PEH in 4 jurisdictions (Cincinnati, Ohio; Denver, Colorado; Sacramento, California; and the Bronx, New York) during July 2021.</p><p><strong>Results: </strong>Findings from 15 focus groups with PEH (n = 53) revealed the need for trusted messengers and consistent messaging across local organizations, as PEH seek to verify information they receive from multiple sources. PEH overwhelmingly preferred to receive health information through face-to-face conversations, especially with healthcare providers with whom they had an established relationship, but they also cited news media, the internet, and social media as their main sources for obtaining health information. PEH reported that effective communication products pair a recommended action with instructions and resources about how to take that action within their community.</p><p><strong>Conclusions: </strong>These findings support healthcare providers collaborating with public health agencies to ensure that infectious disease prevention messages for PEH are provided by trusted messengers, multimodal, paired with resources, and consistent.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S340-S345"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619659/pdf/jiac336.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zachary Shepard, Lilian Vargas Barahona, Gabrielle Montalbano, Sarah E Rowan, Carlos Franco-Paredes, Nancy Madinger
{"title":"Bartonella quintana Infection in People Experiencing Homelessness in the Denver Metropolitan Area.","authors":"Zachary Shepard, Lilian Vargas Barahona, Gabrielle Montalbano, Sarah E Rowan, Carlos Franco-Paredes, Nancy Madinger","doi":"10.1093/infdis/jiac238","DOIUrl":"https://doi.org/10.1093/infdis/jiac238","url":null,"abstract":"<p><strong>Background: </strong>Bartonella quintana is an important cause of infection amongst people experiencing homelessness that is underdiagnosed due to its nonspecific clinical manifestations. We reviewed cases identified in the Denver metropolitan area in 2016-2021.</p><p><strong>Methods: </strong>The electronic medical records from 2 large academic medical centers in Colorado were reviewed for demographic, clinical, and laboratory features of patients with B. quintana infection confirmed by blood culture, serologies, and/or molecular testing from July 2016 to December 2021.</p><p><strong>Results: </strong>Fourteen patients with B. quintana infection were identified. The mean age was 49.5 years (SD 12.7 years) and 92.9% of patients were male. Twelve patients had history of homelessness (85.7%) and 11 were experiencing homelessness at the time of diagnosis (78.6%). Most frequent comorbidities included substance use (78.6%), of which 42.9% had alcohol use disorder. The average time to blood culture positivity was 12.1 days (SD 6.2 days). Three patients with bacteremia had negative B. quintana IgG, and 6 of 14 (42.8%) patients had evidence of endocarditis on echocardiography.</p><p><strong>Conclusions: </strong>B. quintana is an underrecognized cause of serious infection in individuals experiencing homelessness. Serologic and microbiologic testing, including prolonged culture incubation, should be considered in at-risk patients due to ongoing transmission in homeless populations.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S315-S321"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40396098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara A Miller-Archie, Sarah C Walters, Angelica Bocour, Miranda S Moore, Ellen Wiewel, Tejinder Singh, Sungwoo Lim
{"title":"The Impact of Supportive Housing on Liver-Related Outcomes Among Persons With Hepatitis C Virus Infection.","authors":"Sara A Miller-Archie, Sarah C Walters, Angelica Bocour, Miranda S Moore, Ellen Wiewel, Tejinder Singh, Sungwoo Lim","doi":"10.1093/infdis/jiac292","DOIUrl":"https://doi.org/10.1093/infdis/jiac292","url":null,"abstract":"<p><strong>Background: </strong>Hepatitis C virus (HCV) infection disproportionately impacts people experiencing homelessness. Hepatitis C virus can lead to negative health outcomes, including mortality. We evaluated the impact of a permanent supportive housing (PSH) program (ie, \"treatment\") on liver-related morbidity and mortality among persons with chronic homelessness and HCV infection.</p><p><strong>Methods: </strong>We matched records for persons eligible for a New York City PSH program (2007-2014) with Heath Department HCV and Vital Statistics registries and Medicaid claims. Among persons diagnosed with HCV before or 2 years posteligibility, we added stabilized inverse probability of treatment weights to negative binomial regression models to compare rates for liver disease-related emergency department visits and hospitalizations, and hazard ratios for mortality, by program placement 2 and 5 years posteligibility.</p><p><strong>Results: </strong>We identified 1158 of 8783 placed and 1952 of 19 019 unplaced persons with laboratory-confirmed HCV infection. Permanent supportive housing placement was associated with significantly reduced liver-related emergency department visits (adjusted rate ratio [aRR] = 0.76, 95% confidence interval [CI] = .61-.95), hospitalizations (aRR = 0.62, 95% CI = .54-.71), and all-cause (adjusted hazard ratio [aHR] = 0.65, 95% CI = .46-.92) and liver-related mortality (aHR = 0.72, 95% CI = .09-.83) within 2 years. The reduction remained significant for hospitalizations after 5 years.</p><p><strong>Conclusions: </strong>Placement into PSH was associated with reduced liver-related morbidity and mortality among persons with HCV infection and chronic homelessness.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S363-S371"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/35/52/jiac292.PMC9547527.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Crystal Gibson, Casey Schumann, Kimberly Neuschel, Joseph A McBride
{"title":"COVID-19 Vaccination Coverage Among People Experiencing Homelessness in a Highly Vaccinated Midwest County-Dane County, Wisconsin, 2021.","authors":"Crystal Gibson, Casey Schumann, Kimberly Neuschel, Joseph A McBride","doi":"10.1093/infdis/jiac303","DOIUrl":"https://doi.org/10.1093/infdis/jiac303","url":null,"abstract":"<p><p>People experiencing homelessness (PEH) are at increased risk for coronavirus disease 2019 (COVID-19) infection. This study assessed COVID-19 vaccination coverage among vaccine-eligible PEH (5 years and older) stratified by demographic characteristics. PEH were less likely to complete a primary vaccination series than the Dane County population (32.0%; 95% confidence interval [CI], 30.3%-33.8% vs 82.4%; 95% CI, 82.3%-82.5%) and were less likely to have received a booster when eligible (30.8%; 95% CI, 27.8%-33.9% vs 67.2%; 95% CI, 67.1%-67.4%). Vaccination rates were lowest among young PEH and PEH of color.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S335-S339"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619645/pdf/jiac303.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Padma S Jones, Karen W Yeh, Hannah K Brosnan, Dalia Regos-Stewart, Cathy Ngo, Jennifer Kwon, Alicia H Chang
{"title":"Evaluation of the Homeless Management Information System for COVID-19 Surveillance Among People Experiencing Homelessness.","authors":"Padma S Jones, Karen W Yeh, Hannah K Brosnan, Dalia Regos-Stewart, Cathy Ngo, Jennifer Kwon, Alicia H Chang","doi":"10.1093/infdis/jiac335","DOIUrl":"https://doi.org/10.1093/infdis/jiac335","url":null,"abstract":"<p><strong>Background: </strong>Variable and incomplete reporting of housing status creates challenges in the surveillance of coronavirus disease 2019 (COVID-19) among the homeless population in Los Angeles County (LA County) and nationwide.</p><p><strong>Methods: </strong>We developed standard investigation procedures to assess the housing status of LA County COVID-19 patients. Using data sharing procedures, we matched COVID-19 patients to Homeless Management Information System (HMIS) client profiles and supplemented with additional data sources for contributory data points and to further housing status ascertainment.</p><p><strong>Results: </strong>We identified 10 586 COVID-19 patients among people experiencing homelessness (PEH) between 30 March 2020 and 30 December 2021; 2801 (26.5%) patients were first identified from HMIS profile matches, 1877 (17.7%) from quarantine/isolation housing intake rosters, 573 (5.4%) from hospital records, 749 (7.1%) from case and contact interviews, 3659 (34.6%) directly from PEH medical and service providers, and 927 (8.8%) had unknown sources. Among COVID-19 patients matched to HMIS profiles, 5351 (42.5%) were confirmed to be PEH at the time of COVID-19 diagnosis.</p><p><strong>Conclusions: </strong>Interoperability between public health data, HMIS, and external partners have been critical components in evaluating the impact of COVID-19 among the LA County homeless population. No one data source was complete for COVID-19 surveillance in this population.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"S327-S334"},"PeriodicalIF":6.4,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33495226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenny S Maron, Michelle Conroy, Vivek Naranbai, Upeka Samarakoon, Tina Motazedi, Jocelyn R Farmer, Esther Freeman, Aleena Banerji, Yannic C Bartsch, David J Gregory, Mark C Poznansky, Galit Alter, Kimberly G Blumenthal
{"title":"Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 Vaccine.","authors":"Jenny S Maron, Michelle Conroy, Vivek Naranbai, Upeka Samarakoon, Tina Motazedi, Jocelyn R Farmer, Esther Freeman, Aleena Banerji, Yannic C Bartsch, David J Gregory, Mark C Poznansky, Galit Alter, Kimberly G Blumenthal","doi":"10.1093/infdis/jiac107","DOIUrl":"https://doi.org/10.1093/infdis/jiac107","url":null,"abstract":"<p><p>Allergic symptoms after messenger RNA (mRNA) coronavirus disease 2019 (COVID-19) vaccines occur in up to 2% of recipients. Compared to nonallergic controls (n = 18), individuals with immediate allergic reactions to mRNA COVID-19 vaccines (n = 8) mounted lower immunoglobulin G1 (IgG1) to multiple antigenic targets in severe acute respiratory syndrome coronavirus 2 spike following vaccination, with significantly lower IgG1 to full-length spike (P = .04). Individuals with immediate allergic reactions to mRNA COVID-19 vaccines bound Fcγ receptors similarly to nonallergic controls. Although there was a trend toward an overall reduction in opsonophagocytic function in individuals with immediate allergic reactions compared to nonallergic controls, allergic patients produced functional antibodies exhibiting a high ratio of opsonophagocytic function to IgG1 titer.</p>","PeriodicalId":509652,"journal":{"name":"The Journal of Infectious Diseases","volume":" ","pages":"1231-1236"},"PeriodicalIF":6.4,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40317673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}