European Heart Journal - Imaging Methods and Practice最新文献

{"title":"Left ventricular strain-volume loops in bicuspid aortic valve disease: new insights in cardiomechanics","authors":"Z. Keuning, T. P. Kerstens, R. R. Zwaan, D. Bowen, Hendrik J Vos, A. J. V. van Dijk, J. Roos‐Hesselink, Dick H J Thijssen, A. Hirsch, A. E. Van den Bosch","doi":"10.1093/ehjimp/qyae020","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae020","url":null,"abstract":"\u0000 \u0000 \u0000 By combining temporal changes in left ventricular (LV) global longitudinal strain (GLS) with LV volume, LV strain-volume loops can assess cardiac function across the cardiac cycle. This study compared LV strain-volume loops between bicuspid aortic valve (BAV) patients and controls, and investigated the loop’s prognostic value for clinical events.\u0000 \u0000 \u0000 \u0000 From a prospective cohort of congenital heart disease patients, BAV patients were selected and compared with healthy volunteers, who were matched for age and sex at group level. GLS analysis from apical views were used to construct strain-volume loops. Associations with clinical events, i.e. a composite of all-cause mortality, heart failure, arrhythmias and aortic valve replacement, were assessed by Cox regression. 113 BAV patients were included (median age 32 years, 40% female). BAV patients demonstrated lower Sslope (0.21%/mL, [Q1-Q3: 0.17-0.28] vs. 0.27%/mL [0.24-0.34], p < 0.001) and ESslope (0.19%/mL [0.12-0.25] vs. 0.29%/mL [0.21-0.43], p < 0.001) compared to controls, but also greater uncoupling during early (0.48 ± 1.29 vs. 0.06 ± 1.2, p = 0.018) and late diastole (0.66 ± 1.01 vs -0.06 ± 1.09, p < 0.001). Median follow-up duration was 9.9 [9.3-10.4] years. Peak aortic jet velocity (HR 1.22, p = 0.03), enlarged left atrium (HR 3.16, p = 0.003), E/e’ ratio (HR 1.17, p = 0.002), GLS (HR 1.16, p = 0.008) and ESslope (HR 0.66, p = 0.04) were associated with the occurrence of clinical events.\u0000 \u0000 \u0000 \u0000 Greater uncoupling and lower systolic and diastolic slopes were observed in BAV patients compared to healthy controls, suggesting presence of altered LV cardiomechanics. Moreover, lower ESslope was associated with clinical events, highlighting the strain-volume loop’s potential as prognostic marker.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive Pressure-Volume Loops using the Elastance Model and CMR – A Porcine Validation at Transient Preloads","authors":"F. Seemann, E. Heiberg, Christopher G. Bruce, Jaffar M Khan, Amanda Poternask, R. Ramasawmy, M. Carlsson, H. Arheden, R. Lederman, A. Campbell-Washburn","doi":"10.1093/ehjimp/qyae016","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae016","url":null,"abstract":"\u0000 \u0000 \u0000 Pressure-volume (PV) loops have utility in evaluation of cardiac pathophysiology but require invasive measurements. Recently, a time-varying elastance model to derive PV loops noninvasively was proposed, using left ventricular (LV) volume by cardiovascular magnetic resonance (CMR) and brachial cuff pressure as inputs. Validation was performed using CMR and pressure measurements acquired on the same day, but not simultaneously, and without varying preload. This study validate the noninvasive elastance model used to estimate PV loops at varying preloads, compared with simultaneous measurements of invasive pressure and volume from real-time CMR, acquired concurrent to an inferior vena cava (IVC) occlusion.\u0000 \u0000 \u0000 \u0000 We performed dynamic PV loop experiments under CMR-guidance in 15 pigs (n = 7 naïve, n = 8 with ischemic cardiomyopathy). Preload was altered by IVC occlusion while simultaneously acquiring invasive LV pressures and volumes from real-time CMR. Pairing pressure and volume signals yielded invasive PV loops, and model-based PV loops were derived using real-time LV volumes. Hemodynamic parameters derived from invasive and model-based PV loops were compared.\u0000 Across 15 pigs, 323 PV loops were recorded. Intraclass correlation coefficient (ICC) agreement was excellent between model-based and invasive stroke work (bias = 0.007 ± 0.03J, ICC = 0.98), potential energy (bias = 0.02 ± 0.03J, ICC = 0.99), ventricular energy efficiency (bias = -0.7 ± 2.7%, ICC = 0.98), contractility (bias = 0.04 ± 0.1 mmHg/ml, ICC = 0.97), and ventriculoarterial coupling (bias = 0.07 ± 0.15, ICC = 0.99). All hemodynamic parameters differed between naïve and cardiomyopathy animals (p < 0.05). Invasive vs model-based PV loop dice similarity coefficient was 0.88 ± 0.04.\u0000 \u0000 \u0000 \u0000 An elastance model-based estimation of PV loops and associated hemodynamic parameters provided accurate measurements at transient loading conditions compared with invasive PV loops.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biventricular interaction and aortic function in adult patients with repaired tetralogy of Fallot: a 2D-3D speckle tracking echocardiographic study","authors":"A. Vitarelli, L. Capotosto, Fabio Miraldi, K. Mukred, Marco Francone, N. Galea, E. Mangieri, G. Tanzilli, N. Viceconte, Massimo Mancone, Bich Lien Nguyen, Costantino Smaldone, Sulaiman Al-Kindy","doi":"10.1093/ehjimp/qyae015","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae015","url":null,"abstract":"\u0000 \u0000 \u0000 In patients late after correction of tetralogy of Fallot(TOF) the combined effects of preoperative hypertrophy and hypoxia, ventricular interdependence, acquired postoperative lesions such as pulmonary or aortic regurgitation, and congenital vasculopathy may result in impaired right ventricular(RV) as well as left ventricular(LV) function. The aim of the present study was to investigate the interventricular interactions in repaired TOF(rTOF) and the impact of aortic function on biventricular performance using two-dimensional(2DSTE) and three-dimensional speckle tracking echocardiography(3DSTE).\u0000 \u0000 \u0000 \u0000 Twenty-five adult patients with rTOF and twenty-five age- and gender-matched healthy controls were studied. LV and RV volumes were determined by 3DSTE and cardiac magnetic resonance(CMR). LV and RV longitudinal(LVLS, RVLS) and area strains(LVAS, RVAS) and LV twist/rotation were calculated by 3DSTE. Ascending aorta circumferential strain(AAo-CS) was obtained using 2DSTE.\u0000 \u0000 \u0000 \u0000 LV-3DSTE parameters were decreased in rTOF patients compared to controls even in patients with normal ejection fraction. AAo-CS was decreased(6.7±1.9 vs 10.1±2.6, p=0.003) in rTOF patients compared to controls even in the presence of normal aortic dimensions and correlated with AAo diameter(r=-0.69, p=0.0001), LV twist(r=0.54, p=0.004), LVAS(r=-0.56, p=0.003) and RVLS(r=-0.39, p=0.036). LVAS an AAo-CS were associated with disease severity (peak oxygen consumption, arrhythmia occurrence). Significant improvement in global χ2 value was noted with RV-3DSTE parameters + LVAS + AAo-CS compared to RV dysfunction alone for detecting exercise capacity impairment(from 77.1 to 84.4 to 91.2, p=0.003).\u0000 \u0000 \u0000 \u0000 Speckle-tracking echocardiography revealed subtle LV and AAo dysfunction in adults with rTOF. A correlation was observed between LV and RV strain changes as well as between AAo strain impairment and LV/RV dysfunction. LV and AAo changes had an incremental value in evaluating disease severity.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"51 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celebrating a Year of Collaboration: Gratitude to Our Inaugural Reviewers","authors":"Alessia Gimelli","doi":"10.1093/ehjimp/qyae014","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae014","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"33 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in referral trends and clinical characteristics in evaluation of stable coronary artery disease (CAD) by Myocardial Perfusion Scintigraphy (MPS): A 20-year analysis from a tertiary referral center","authors":"S. Lakshmanan, Paolo Frumento, Stefano Dalmiani, A. Giorgetti, A. Gimelli","doi":"10.1093/ehjimp/qyae013","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae013","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"2000 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How international organizations can support the development of CardioOncology in the Latin American and the Caribbean (LAC) region","authors":"Amelia Peix, Manuel Bazan, Jorge E Aguiar, Jesus Sanchez, E. Estrada, Aurelio Mendoza, Diana Paez","doi":"10.1093/ehjimp/qyae005","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae005","url":null,"abstract":"\u0000 Health problems in the Latin American and the Caribbean (LAC) region are highly concentrated on non-communicable diseases (NCDs), being cardiovascular diseases (CVDs) and cancer the leading causes of death. Different countries of the region are at different stages of development in addressing CVDs and cancer. Opportunities for training and continuing education in cardio-oncology, as well as active cardio-oncology groups, are primarily limited to large academic institutions in major metropolitan areas. In addition, the development of advanced imaging modalities in LAC faces challenges such as the high cost of equipment, a lack of equipment maintenance and service, as well as insufficient specific training for both imaging specialists and referring clinicians. To contribute to the implementation of actionable strategies ensuring equitable access to care for all, international organizations, such as the IAEA, offer support for the regional development of health projects that address educational needs. In this context, a new IAEA regional cooperation project for LAC titled “Strengthening of regional capacities on the use of Nuclear Medicine techniques in a Cardio-oncology multimodality approach in patients with cancer” will be developed during 2024-2025. The experience of some centers, as well as national experiences in certain countries of the region, that have been previously involved in other regional projects, can be leveraged for the benefit of the entire region. We present a proposed road map for cross-institutional/countries collaboration in the development of cardio-oncology in the LAC region, contributing to decreasing the barriers to the growth of the subspecialty.","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"28 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139964246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between peripheral endothelial function and myocardial perfusion in patients with coronary artery disease","authors":"N. Vartiainen, J. Hartikainen, T. Laitinen, P. Kuikka, H. Mussalo, T. Laitinen","doi":"10.1093/ehjimp/qyae010","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae010","url":null,"abstract":"\u0000 \u0000 \u0000 Endothelial dysfunction is a systemic disorder and risk factor for atherosclerosis. Our aim was to assess whether there is a relation between peripheral endothelial function and myocardial perfusion in patients with coronary artery disease.\u0000 \u0000 \u0000 \u0000 We prospectively studied 54 patients, who had a positive result for obstructive coronary artery disease in coronary CT angiography. Myocardial perfusion (15O)H2O PET/CT was imaged at rest and during adenosine-induced maximal vasodilation. Peripheral endothelial function was assessed by measuring flow-mediated dilation with ultrasound from the left brachial artery.\u0000 \u0000 \u0000 \u0000 There was a statistically significant correlation between flow-mediated dilation and global hyperemic myocardial blood flow (r = 0.308, p = 0.023). The correlation remained statistically significant when controlling for gender, height and diastolic blood pressure at rest (r = 0.367, p = 0.008). Receiver operating character analysis, however, yielded an area under curve of only 0.559 (p = 0.492) when flow-mediated dilation was used to predict reduced myocardial blood flow (below 2.3 ml/g/min). Patients with significantly decreased myocardial blood flow (n = 14) underwent invasive coronary angiography. Flow-mediated dilation showed an inverse correlation with the severity of the most significant stenosis (r = -0.687, p = 0.007).\u0000 \u0000 \u0000 \u0000 Peripheral endothelial function is related with hyperemic MBF and with the severity of CAD in invasive coronary angiography. Due to insufficient sensitivity and specificity in the identification of reduced myocardial blood flow, FMD is not suitable for clinical practice at the individual level. However, it works at the population level as a research tool when assessing endothelial dysfunction in patients with coronary artery disease.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"293 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139839977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between peripheral endothelial function and myocardial perfusion in patients with coronary artery disease","authors":"N. Vartiainen, J. Hartikainen, T. Laitinen, P. Kuikka, H. Mussalo, T. Laitinen","doi":"10.1093/ehjimp/qyae010","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae010","url":null,"abstract":"\u0000 \u0000 \u0000 Endothelial dysfunction is a systemic disorder and risk factor for atherosclerosis. Our aim was to assess whether there is a relation between peripheral endothelial function and myocardial perfusion in patients with coronary artery disease.\u0000 \u0000 \u0000 \u0000 We prospectively studied 54 patients, who had a positive result for obstructive coronary artery disease in coronary CT angiography. Myocardial perfusion (15O)H2O PET/CT was imaged at rest and during adenosine-induced maximal vasodilation. Peripheral endothelial function was assessed by measuring flow-mediated dilation with ultrasound from the left brachial artery.\u0000 \u0000 \u0000 \u0000 There was a statistically significant correlation between flow-mediated dilation and global hyperemic myocardial blood flow (r = 0.308, p = 0.023). The correlation remained statistically significant when controlling for gender, height and diastolic blood pressure at rest (r = 0.367, p = 0.008). Receiver operating character analysis, however, yielded an area under curve of only 0.559 (p = 0.492) when flow-mediated dilation was used to predict reduced myocardial blood flow (below 2.3 ml/g/min). Patients with significantly decreased myocardial blood flow (n = 14) underwent invasive coronary angiography. Flow-mediated dilation showed an inverse correlation with the severity of the most significant stenosis (r = -0.687, p = 0.007).\u0000 \u0000 \u0000 \u0000 Peripheral endothelial function is related with hyperemic MBF and with the severity of CAD in invasive coronary angiography. Due to insufficient sensitivity and specificity in the identification of reduced myocardial blood flow, FMD is not suitable for clinical practice at the individual level. However, it works at the population level as a research tool when assessing endothelial dysfunction in patients with coronary artery disease.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"48 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139780048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular magnetic resonance imaging-derived intraventricular pressure gradients in ST-segment elevation myocardial infarction: a long-term follow-up study","authors":"Lara S F Konijnenberg, C. Beijnink, Maarten van Lieshout, J. L. Vos, L. Rodwell, V. Bodí, José T Ortiz-Pérez, Niels van Royen, J. R. Rodríguez Palomares, R. Nijveldt","doi":"10.1093/ehjimp/qyae009","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae009","url":null,"abstract":"\u0000 \u0000 \u0000 Recently, novel post-processing tools have become available that measure intraventricular pressure gradients (IVPG) on routinely obtained long-axis cine cardiac magnetic resonance (CMR) images. IVPGs provide a comprehensive overview of both systolic and diastolic left ventricular (LV) function. Whether IVPGs are associated with clinical outcome after ST-elevation myocardial infarction (STEMI) is currently unknown. Here, we investigated the association between CMR-derived LV-IVPGs and major adverse cardiovascular events (MACE) in a large reperfused STEMI cohort with long-term outcome.\u0000 \u0000 \u0000 \u0000 In this prospectively enrolled multicentre cohort study, 307 patients underwent CMR within 14 days after first STEMI. LV-IVPGs (from apex-to-base) were estimated on the long-axis cine images. During a median follow-up of 9.7 [5.9-12.5] years, MACE (i.e., composite of cardiovascular death and de novo heart failure hospitalisation) occurred in 49 patients (16.0%). These patients had larger infarcts, more often microvascular injury and impaired LV-IVPGs. In univariable Cox regression, overall LV-IVPG was significantly associated with MACE and remained significantly associated after adjustment for common clinical risk factors (HR 0.873, 95% CI 0.794-0.961, p = 0.005) and myocardial injury parameters (HR 0.906, 95% CI 0.825-0.995, p = 0.038). However, adjusted for LV ejection fraction and LV global longitudinal strain, overall LV-IVPG does not provide additional prognostic information (HR 0.959, 95% CI 0.866-1.063, p = 0.426).\u0000 \u0000 \u0000 \u0000 Early after STEMI, CMR-derived LV-IVPGs are univariably associated with MACE and this association remains significant after adjustment for common clinical risk factors and measures of infarct severity. However, LV-IVPGs do not add prognostic value to LV ejection fraction and LV global longitudinal strain.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"394 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139847924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular magnetic resonance imaging-derived intraventricular pressure gradients in ST-segment elevation myocardial infarction: a long-term follow-up study","authors":"Lara S F Konijnenberg, C. Beijnink, Maarten van Lieshout, J. L. Vos, L. Rodwell, V. Bodí, José T Ortiz-Pérez, Niels van Royen, J. R. Rodríguez Palomares, R. Nijveldt","doi":"10.1093/ehjimp/qyae009","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae009","url":null,"abstract":"\u0000 \u0000 \u0000 Recently, novel post-processing tools have become available that measure intraventricular pressure gradients (IVPG) on routinely obtained long-axis cine cardiac magnetic resonance (CMR) images. IVPGs provide a comprehensive overview of both systolic and diastolic left ventricular (LV) function. Whether IVPGs are associated with clinical outcome after ST-elevation myocardial infarction (STEMI) is currently unknown. Here, we investigated the association between CMR-derived LV-IVPGs and major adverse cardiovascular events (MACE) in a large reperfused STEMI cohort with long-term outcome.\u0000 \u0000 \u0000 \u0000 In this prospectively enrolled multicentre cohort study, 307 patients underwent CMR within 14 days after first STEMI. LV-IVPGs (from apex-to-base) were estimated on the long-axis cine images. During a median follow-up of 9.7 [5.9-12.5] years, MACE (i.e., composite of cardiovascular death and de novo heart failure hospitalisation) occurred in 49 patients (16.0%). These patients had larger infarcts, more often microvascular injury and impaired LV-IVPGs. In univariable Cox regression, overall LV-IVPG was significantly associated with MACE and remained significantly associated after adjustment for common clinical risk factors (HR 0.873, 95% CI 0.794-0.961, p = 0.005) and myocardial injury parameters (HR 0.906, 95% CI 0.825-0.995, p = 0.038). However, adjusted for LV ejection fraction and LV global longitudinal strain, overall LV-IVPG does not provide additional prognostic information (HR 0.959, 95% CI 0.866-1.063, p = 0.426).\u0000 \u0000 \u0000 \u0000 Early after STEMI, CMR-derived LV-IVPGs are univariably associated with MACE and this association remains significant after adjustment for common clinical risk factors and measures of infarct severity. However, LV-IVPGs do not add prognostic value to LV ejection fraction and LV global longitudinal strain.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":" 77","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139788137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}