Acupuncture & Electro-Therapeutics Research最新文献

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Cerebroprotective Effect of Acupuncture on Ischemic Stroke by Inhibiting Ferroptosis via the SLC7A11/GPX4 Pathway 针刺通过SLC7A11/GPX4途径抑制铁下垂对缺血性脑卒中的脑保护作用
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2026-04-28 DOI: 10.1177/03601293261446017
Jing Xue, Jian Yang, Ruiqi Wang, Ying Gao, Shu Wang
{"title":"Cerebroprotective Effect of Acupuncture on Ischemic Stroke by Inhibiting Ferroptosis via the SLC7A11/GPX4 Pathway","authors":"Jing Xue, Jian Yang, Ruiqi Wang, Ying Gao, Shu Wang","doi":"10.1177/03601293261446017","DOIUrl":"https://doi.org/10.1177/03601293261446017","url":null,"abstract":"Objective Clinical studies have shown that acupuncture can promote functional recovery after ischemic stroke. This study aimed to evaluate the neuroprotective effects of manual acupuncture in a rat model of ischemic stroke and to investigate whether these effects are associated with ferroptosis and changes in the SLC7A11/GPX4 axis. Methods A middle cerebral artery occlusion (MCAO) model was established in rats. The neuroprotective effects of manual acupuncture were evaluated using the modified Neurological Severity Score (mNSS) and 2,3,5-triphenyltetrazolium chloride (TTC) staining. Mitochondrial ultrastructure was examined by transmission electron microscopy. Iron deposition was assessed by Prussian blue staining, and glutathione peroxidase 4 (GPX4) expression was analyzed by immunofluorescence. Biochemical assays were used to measure ferroptosis-related biomarkers, including iron, glutathione (GSH), and malondialdehyde (MDA). Western blot analysis was performed to assess the expression of solute carrier family 7 member 11 (SLC7A11) and GPX4. Results Ferroptosis-related changes were observed in ischemic brain regions of MCAO rats. Manual acupuncture significantly improved neurological outcomes, reduced cerebral infarct volume, and modulated ferroptosis-related markers (↓MDA, ↓iron deposition; ↑GSH, ↑GPX4/SLC7A11). These effects were enhanced by co-treatment with the ferroptosis inhibitor desferrioxamine (DFO) and attenuated by co-treatment with the ferroptosis inducer imidazole ketone erastin (IKE), supporting the involvement of ferroptosis-related mechanisms in acupuncture-mediated neuroprotection. Conclusion This study suggests that manual acupuncture exerts neuroprotective effects in MCAO rats and is associated with reduced ferroptosis-related injury, with increased SLC7A11 and GPX4 expression.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147967062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Warm Acupuncture Combined with Cervical and Lumbar Chiropractic Manipulation on Pain Severity, Lumbar Function, and Serum IL-1β, IL-6, and TNF-α Levels in Patients with LDH 温针配合颈腰椎捏脊手法对LDH患者疼痛程度、腰椎功能及血清IL-1β、IL-6、TNF-α水平的影响
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2026-02-16 DOI: 10.1177/03601293261422225
Shiyao Zhang, Yufeng He, LongMing Lei, Jun Zhao, Meiling Yi, Xu Tang, Chaonong Luo, Weidong Lin, Junneng Huang
{"title":"Warm Acupuncture Combined with Cervical and Lumbar Chiropractic Manipulation on Pain Severity, Lumbar Function, and Serum IL-1β, IL-6, and TNF-α Levels in Patients with LDH","authors":"Shiyao Zhang, Yufeng He, LongMing Lei, Jun Zhao, Meiling Yi, Xu Tang, Chaonong Luo, Weidong Lin, Junneng Huang","doi":"10.1177/03601293261422225","DOIUrl":"https://doi.org/10.1177/03601293261422225","url":null,"abstract":"Objective This study aimed to explore the influences of warm acupuncture in combination with cervical and lumbar chiropractic manipulation on serum inflammatory factors, lumbar function, and pain severity in patients with lumbar disc herniation (LDH). Methods We selected and divided 108 LDH patients who were admitted to our hospital from October 2023 to October 2025 randomly by applying the random number table method into a control group ( n = 54, receiving cervical and lumbar chiropractic manipulation) and a combined group ( n = 54, receiving warm acupuncture in addition to the control treatment). Both groups received continuous treatment for 30 days. Between the two groups, we compared the clinical efficacy after treatment, lumbar function [Japanese Orthopaedic Association (JOA) score, Oswestry Disability Index (Oswestry) score, and Fairbank JC score], and inflammatory factors [interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α] before and after treatment. Results After treating for 30 days, in the combined group, the total effective rate was 96.30%, which is higher than that of 83.33% of the control group ( P < 0.05). After treatment, compared with those in the control group, the Oswestry score, Fairbank JC score, and IL-1β, IL-6, and TNF-α levels were lower in the combined group ( P < 0.05), while the JOA score was higher ( P < 0.05). Conclusion Warm acupuncture combined with cervical and lumbar chiropractic manipulation can reduce inflammatory factor attacks, improve lumbar function in LDH patients, and relieve lumbar muscle fatigue and has certain clinical value.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective Effect of Pretreatment of Astragalus membranaceus Injection at Five Zang-Organ Shu Acupoints in D-gal–Induced Aging Rats 黄芪注射液五脏器俞穴预处理对d -gal诱导衰老大鼠的保护作用
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2025-07-03 DOI: 10.1177/03601293251356851
Shan Zhong, Xilin Wang, Yuan Guo, Jingren Chen, Qing Lin, Shumin Wen, Yuhong Chen, Songzhe He
{"title":"Protective Effect of Pretreatment of <i>Astragalus membranaceus</i> Injection at Five Zang-Organ Shu Acupoints in D-gal–Induced Aging Rats","authors":"Shan Zhong, Xilin Wang, Yuan Guo, Jingren Chen, Qing Lin, Shumin Wen, Yuhong Chen, Songzhe He","doi":"10.1177/03601293251356851","DOIUrl":"https://doi.org/10.1177/03601293251356851","url":null,"abstract":"Background Aging is a progressive process associated with the decline of both cell structure and function, involving oxidative stress as well as mitochondrial dysfunction. However, strategies to delay the aging process have become a research hotspot that an increasing number of researchers are focusing on. This study aimed to explore the protective effect of pretreatment of Astragalus membranaceus (AM) injection at five Zang-organ Shu acupoints in D-galactose (D-gal)–induced aging rats. Methods The rats received acupoint injections of the five Zang-organ Shu acupoints [Feishu (BL 13), Xinshu (BL 15), Ganshu (BL 18), Pishu (BL 20), and Shenshu (BL 23)] with AM injection prior to intraperitoneal injection of D-gal. Organ indexes, biochemical serum parameters, histopathological morphology, and aging-related protein levels of the brain and kidney tissues were used to evaluate the oxidative alterations induced by D-gal and the protective role of AM injection. Results AM injection improved organ indexes, biochemical serum parameters, and the pathological damage of the brain and kidney tissues. Primary mechanism analysis showed that AM injection decreased the expression of aging markers (p53 and p16) in the hippocampus of aging rats. Furthermore, AM injection significantly decreased malondialdehyde (MDA) levels and increased superoxide dismutase (SOD) activity, enhancing the antioxidant status. Conclusion Pretreatment of AM injection at five Zang-organ Shu acupoints ameliorates oxidative stress induced by D-gal in the rats through downregulation of aging markers (p53 and p16), a decrease in SOD activity, and an increase in MDA content.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"49 4","pages":"242-256"},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147892527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Risk Analysis of Pneumothorax Caused by Acupuncture and its Prevention and Control 针刺致气胸的风险分析及防治
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2024-01-04 DOI: 10.3727/036012924x17043759937459
Chen Biwei, Gong Changzhen, Chen Shaoz, Chen Shaozong
{"title":"Risk Analysis of Pneumothorax Caused by Acupuncture and its Prevention and Control","authors":"Chen Biwei, Gong Changzhen, Chen Shaoz, Chen Shaozong","doi":"10.3727/036012924x17043759937459","DOIUrl":"https://doi.org/10.3727/036012924x17043759937459","url":null,"abstract":"Although acupuncture therapy has a record of effectiveness and safety, the safety of acupuncture therapy requires both systematized professional skills and standardized application. In fact, acupuncture therapy has potential risk. Pneumothorax caused by acupuncture is a serious injury caused by this therapy. The causes are mainly related to improper needling depth, angle, manipulation, and selection of acupoints. In China, the medical institutions in which pneumothorax by acupuncture occurs are mainly community clinics, which reflects the lack of professional training of acupuncture practitioners in grass-roots medical and health institutions. Its prevention and control are discussed.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"48 4","pages":"269-281"},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Study of Opposing Needling Combined With Eye Acupuncture Therapy for Treatment of Muscle Spasm in Post-stroke Hemiplegia Patients Therapy for Treatment of Muscle Spasm in Post-Stroke Hemiplegia Patients 对针联合眼针治疗脑卒中后偏瘫患者肌肉痉挛的临床研究
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2023-08-17 DOI: 10.3727/036012923x168907527894626
Guanghui Liu, Tingting Li, Hongyuan Zhang, Huiting Yang, Jian Wang, Zhe Zhang, Juan Liu, Wenjun Zhang, Shi Zhang, Yang Wang
{"title":"Clinical Study of Opposing Needling Combined With Eye Acupuncture Therapy for Treatment of Muscle Spasm in Post-stroke Hemiplegia Patients Therapy for Treatment of Muscle Spasm in Post-Stroke Hemiplegia Patients","authors":"Guanghui Liu, Tingting Li, Hongyuan Zhang, Huiting Yang, Jian Wang, Zhe Zhang, Juan Liu, Wenjun Zhang, Shi Zhang, Yang Wang","doi":"10.3727/036012923x168907527894626","DOIUrl":"https://doi.org/10.3727/036012923x168907527894626","url":null,"abstract":"Objective: To observe the clinical efficacy of opposing needling combined with eye acupuncture therapy on muscle spasm in post-stroke hemiplegia patients. Methods: A total of 69 post-stroke hemiplegia patients with muscle spasm who were hospitalized in the Department of Encephalopathy Rehabilitation, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected as the research participants. The randomized controlled clinical trial design method was used, and they were randomly divided into the basic treatment group and the combination treatment group. The basic treatment group did not use acupuncture treatment, but only basic rehabilitation treatment. The combination treatment group was treated with opposing needling combined with eye acupuncture therapy. Both groups were treated once a day, and two days were rested after five days of continuous treatment. Five days were a course of treatment, and a total of three courses were treated. The efficacy of opposing needling combined with eye acupuncture therapy for treatment of muscle spasm in post-stroke hemiplegia patients was evaluated. The clinical neurological deficit score scale (CSS), modified Ashworth spasticity scale (MAS), simplified Fugl-Meyer scale (FMA), Barthel index scale (BI) and total score were compared between the two groups before and after treatment. Results: There was no significant difference in CSS scores between the two groups before treatment (P>0.05). After 19 days of treatment, the CSS scores of the two groups were significantly decreased compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in MAS scores between the two groups before treatment (P>0.05). After 19 days of treatment, the MAS scores of the two groups were significantly decreased compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in FMA scores between the two groups before treatment (P>0.05). After 19 days of treatment, the FMA scores of the two groups were significantly improved compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in BI scores between the two groups before treatment (P>0.05). After 19 days of treatment, the BI scores of the two groups were significantly improved compared with those before treatment, and the difference was statistically significant (P<0.05). Conclusion: Compared with the single treatment method, opposing needling combined with eye acupuncture in the treatment of muscle spasm in post-stroke hemiplegia patients has significant advantages in clinical neurological function, spastic improvement, motor function and daily living ability, and has obvious clinical significance in the long-term prognosis of patients.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Acupuncture on the Serum and Local Microcirculatory Biochemical Parameters in Phantom Limb Pain 针刺对幻肢痛患者血清及局部微循环生化指标的影响
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2023-08-17 DOI: 10.3727/036012923x168667953174923
Hong mei Liu, Fan Yang, Ji wei Duan, Zeng yong Li, Hui qin Luan, Wei yan Ren
{"title":"Effect of Acupuncture on the Serum and Local Microcirculatory Biochemical Parameters in Phantom Limb Pain","authors":"Hong mei Liu, Fan Yang, Ji wei Duan, Zeng yong Li, Hui qin Luan, Wei yan Ren","doi":"10.3727/036012923x168667953174923","DOIUrl":"https://doi.org/10.3727/036012923x168667953174923","url":null,"abstract":"Phantom limb pain (PLP) often occurs in post - amputation patients. Acupuncture may have a positive effect in treating PLP. This study aimed to observe the changes in plasma neuropeptide Y (NPY) and prostaglandin E2 (PGE2) levels before and after acupuncture in patients with PLP, and to evaluate the effects of acupuncture on the peripheral circulation of residual limbs by measuring the skin blood flow (SBF) and oxygen saturation (SO 2 ). Six amputees participated in this study. After 28 days of treatment, the PGE2 was significantly lower compared with that at day 0. The NPY was lower compared with that at day 0. The SBF and SO 2 change percentage in the intervention and recovery stages of each acupuncture treatment were all significantly increased. Moreover, the visual analog scale scores of PLP showed that patients felt their PLP disappeared completely and were satisfied with the acupuncture treatment. This study suggests that acupuncture was effective in treating PLP, and PGE2 and NPY may be regulators of pain transmission in PLP.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"323 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catgut Implantation at Acupoints has an Immunosuppressive Effect on Autoimmune Uveitis by Reducing Th1/Th17 Lymphocytes 穴位埋线通过降低Th1/Th17淋巴细胞对自身免疫性葡萄膜炎的免疫抑制作用
4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2023-03-01 DOI: 10.3727/036012923x16800143458347
Feifei Chen, Jianying Zhao, Shuyang Zhong, Fengming Zheng, Xiaobo Hao
{"title":"Catgut Implantation at Acupoints has an Immunosuppressive Effect on Autoimmune Uveitis by Reducing Th1/Th17 Lymphocytes","authors":"Feifei Chen, Jianying Zhao, Shuyang Zhong, Fengming Zheng, Xiaobo Hao","doi":"10.3727/036012923x16800143458347","DOIUrl":"https://doi.org/10.3727/036012923x16800143458347","url":null,"abstract":"Catgut implantation at acupoints (CIA) has been applied as medical treatment for autoimmune diseases. Yet, its effect and mechanism of this therapy on autoimmune uveitis is still unknown. Here we aimed to explore the immunoregulatory effect of CIA in the experimental autoimmune uveitis (EAU) rat model. Lewis rats were induced with EAU by injecting IRBP1177 – 1191 peptide, and subsequently treated with CIA. In the CIA group, delayed mild inflammation was observed with alleviated infiltration of lymphocytes and ocular damage. Flow cytometry showed significant decrease in Th17 lymphocytes at Day 9, 13, and 18 post-immunizations ( P <0.05) after CIA. The Th1 lymphocytes were also significantly decreased at Day 13 and 18 post-immunizations ( P <0.05) in the CIA group. IL-17 and IFN- γ mRNA levels were notably decreased at Day 9, 13 and 18 post-immunizations (P <0.05) after CIA. Serum IL-17 and IFN- γ levels in the CIA group were significantly decreased at Day 9, 13 and 18 post-immunizations ( P <0.05). Ocular inflammation was markedly inhibited after catgut implantation at Pishu (BL20) and Shenshu (BL23) acupoints in the EAU-induced rats. In summary, this study revealed that CIA could reduce Th1 and Th17 lymphocytes and the expression of IFN- γ and IL -17 in the EAU rat model, suggesting its potential in uveitis treatment.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135289976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discussion on the Theoretical Basis for Acupuncture to Improve Knee Osteoarthritis from "Intestinal Microecology" 从“肠道微生态”谈针刺治疗膝关节骨性关节炎的理论基础
IF 0.3 4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2021-08-24 DOI: 10.3727/036012921x16281724938195
Tian-Qi Wang, Ya-jie Wang, Si-Tong Xu
{"title":"Discussion on the Theoretical Basis for Acupuncture to Improve Knee Osteoarthritis from \"Intestinal Microecology\"","authors":"Tian-Qi Wang, Ya-jie Wang, Si-Tong Xu","doi":"10.3727/036012921x16281724938195","DOIUrl":"https://doi.org/10.3727/036012921x16281724938195","url":null,"abstract":"The balance of the intestinal microecosystem is essentially consistent with the theory of \"Yin Ping Yang Mi\" in Chinese medicine. The imbalance of the intestinal microenvironment's homeostasis is closely related to the occurrence of diseases. Acupuncture and moxibustion can\u0000 improve the disease state by regulating the stability of the intestinal microecology, which has a certain theoretical basis. By exploring the law of the body's meridian circulation, it provides a theoretical basis for studying the regulation of acupuncture on the intestinal microecology of\u0000 patients with knee osteoarthritis (KOA).","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43339386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Electroacupuncture on Acupoints of Yanglingquan (GB34) on Gallbladder Volume and Gallbladder Arterial Hemodynamics in Patients With Chronic Cholecystitis 电针阳陵泉穴(GB34)对慢性胆囊炎患者胆囊容积及胆囊动脉血流动力学的影响
IF 0.3 4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2021-08-24 DOI: 10.3727/036012921x16281724938122
Hong-chun Zhang, Yi-Tong Wang, Zi-yang Cao
{"title":"Influence of Electroacupuncture on Acupoints of Yanglingquan (GB34) on Gallbladder Volume and Gallbladder Arterial Hemodynamics in Patients With Chronic Cholecystitis","authors":"Hong-chun Zhang, Yi-Tong Wang, Zi-yang Cao","doi":"10.3727/036012921x16281724938122","DOIUrl":"https://doi.org/10.3727/036012921x16281724938122","url":null,"abstract":"Introduction: In China, patients with chronic cholecystitis account for approximately 10% of the total population, in which over 90% of cholecystitis is caused by cholelithiasis. This study aimed to discuss the possible mechanism of electroacupuncture on the Yanglingquan acupoint\u0000 promoting gallbladder contractibility of patients with chronic cholecystitis. Methods: 60 patients were randomly divided into a trial group and a control group. Doppler ultrasound and color Doppler blood flow imaging was applied. The trial group adopted the BT701-1B electroanesthesia\u0000 apparatus to perform electroacupuncture on the bilateral acupoints of Yanglingquan, while electroacupuncture was made on sham acupoints in the control group. Results: Before the electroacupuncture, gallbladder volume was 49.6 ± 5.66 ml, after 15 min and 30 min of electroacupuncture,\u0000 the gallbladder volume was then 32.9 ± 5.66 ml and 23.0 ± 2.83 ml respectively. The comparison before and after electroacupuncture was obviously and statistically different (P < 0.01). The comparison between after 15 min and 30 min is obviously statistically different (P <\u0000 0.01). Before the electroacupuncture, the gallbladder artery Vmax, Vmin, and RI were 18.4 ± 2.69 cm/s, 9.7 ± 0.07 cm/s, and 0.47 ± 0.06, respectively; the cystic artery Vmax, Vmin, and RI after 30 min were 8.1 ± 0.92 cm/s, 3.1 ± 0.57 cm/s, and 0.61 ±\u0000 0.02. The comparison in gallbladder artery Vmax and Vmin and the drag index (RI) before and after electroacupuncture was obviously and statistically different (P < 0.01). Conclusions: Electroacupuncture on the acupoints of Yanglingquan has the potential to promote the emptying of\u0000 the gallbladder. The mechanism may be related to that the smooth muscle of the gallbladder contracts after electroacupuncture and the gallbladder empties.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45773358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visualized Analysis of Research Hotspots in Acupuncture-Neuro Immunoregulation Based on Bibliometrics 基于文献计量学的针刺-神经免疫调节研究热点可视化分析
IF 0.3 4区 医学
Acupuncture & Electro-Therapeutics Research Pub Date : 2021-08-24 DOI: 10.3727/036012921x16281724938078
Tian-Qi Wang, Liming Sun, Le-Xin Hao, Yu Guo, Yue Zhang, Xin-xin Feng
{"title":"Visualized Analysis of Research Hotspots in Acupuncture-Neuro Immunoregulation Based on Bibliometrics","authors":"Tian-Qi Wang, Liming Sun, Le-Xin Hao, Yu Guo, Yue Zhang, Xin-xin Feng","doi":"10.3727/036012921x16281724938078","DOIUrl":"https://doi.org/10.3727/036012921x16281724938078","url":null,"abstract":"Objective: To review the development of acupuncture and moxibustion-neural network regulation research systematically and comprehensively in China. Method: This study adopted co-word analysis, cluster analysis and other bibliometric methods such as SATI3.2, Citespace and Gephi to visually\u0000 demonstrate the annual publication volume, cooperation between institutions and co-authorship in the field of acupuncture-neuro immunoregulation research based on the data of more than 70 papers on related topics covering a period of 24 years from 1997 to 2020 in China. Results: The results\u0000 show that there are three major research institutions in the field of acupuncture-neuro immunoregulation, namely Shanghai, Zhejiang major research institutions in the field of acupuncture-neuro immunoregulation, namely Shanghai, Zhejiang and Heilongjiang Universities of Traditional Chinese\u0000 Medicine, as well as 7 clusters, including immune function, acupuncture therapy and endogenous opioid peptide. In the future research, a more comprehensive system will be constructed based on the gradually clear relationship between meridians and nerve regulation, humoral regulation, and immune\u0000 regulation. Application practice will combine traditional acupuncture with modern medicine to create a variety of new therapies, such as electroacupuncture, electric acupuncture, and acupoint injection. Conclusion: The research focus will be expanded on how to improve the clinical efficacy\u0000 of multiple combined therapies such as acupuncture for the prevention and treatment of diseases through the regulation of immune cells and immune molecules as well as the regulation of the \"acupuncture-meridian- neuroendocrine-immune\" network.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47279064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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