Acupuncture & Electro-Therapeutics Research最新文献

{"title":"Clinical Study of Opposing Needling Combined With Eye Acupuncture Therapy for Treatment of Muscle Spasm in Post-stroke Hemiplegia Patients Therapy for Treatment of Muscle Spasm in Post-Stroke Hemiplegia Patients","authors":"Guanghui Liu, Tingting Li, Hongyuan Zhang, Huiting Yang, Jian Wang, Zhe Zhang, Juan Liu, Wenjun Zhang, Shi Zhang, Yang Wang","doi":"10.3727/036012923x168907527894626","DOIUrl":"https://doi.org/10.3727/036012923x168907527894626","url":null,"abstract":"Objective: To observe the clinical efficacy of opposing needling combined with eye acupuncture therapy on muscle spasm in post-stroke hemiplegia patients. Methods: A total of 69 post-stroke hemiplegia patients with muscle spasm who were hospitalized in the Department of Encephalopathy Rehabilitation, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected as the research participants. The randomized controlled clinical trial design method was used, and they were randomly divided into the basic treatment group and the combination treatment group. The basic treatment group did not use acupuncture treatment, but only basic rehabilitation treatment. The combination treatment group was treated with opposing needling combined with eye acupuncture therapy. Both groups were treated once a day, and two days were rested after five days of continuous treatment. Five days were a course of treatment, and a total of three courses were treated. The efficacy of opposing needling combined with eye acupuncture therapy for treatment of muscle spasm in post-stroke hemiplegia patients was evaluated. The clinical neurological deficit score scale (CSS), modified Ashworth spasticity scale (MAS), simplified Fugl-Meyer scale (FMA), Barthel index scale (BI) and total score were compared between the two groups before and after treatment. Results: There was no significant difference in CSS scores between the two groups before treatment (P>0.05). After 19 days of treatment, the CSS scores of the two groups were significantly decreased compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in MAS scores between the two groups before treatment (P>0.05). After 19 days of treatment, the MAS scores of the two groups were significantly decreased compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in FMA scores between the two groups before treatment (P>0.05). After 19 days of treatment, the FMA scores of the two groups were significantly improved compared with those before treatment, and the difference was statistically significant (P<0.05). There was no significant difference in BI scores between the two groups before treatment (P>0.05). After 19 days of treatment, the BI scores of the two groups were significantly improved compared with those before treatment, and the difference was statistically significant (P<0.05). Conclusion: Compared with the single treatment method, opposing needling combined with eye acupuncture in the treatment of muscle spasm in post-stroke hemiplegia patients has significant advantages in clinical neurological function, spastic improvement, motor function and daily living ability, and has obvious clinical significance in the long-term prognosis of patients.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Acupuncture on the Serum and Local Microcirculatory Biochemical Parameters in Phantom Limb Pain","authors":"Hong mei Liu, Fan Yang, Ji wei Duan, Zeng yong Li, Hui qin Luan, Wei yan Ren","doi":"10.3727/036012923x168667953174923","DOIUrl":"https://doi.org/10.3727/036012923x168667953174923","url":null,"abstract":"Phantom limb pain (PLP) often occurs in post - amputation patients. Acupuncture may have a positive effect in treating PLP. This study aimed to observe the changes in plasma neuropeptide Y (NPY) and prostaglandin E2 (PGE2) levels before and after acupuncture in patients with PLP, and to evaluate the effects of acupuncture on the peripheral circulation of residual limbs by measuring the skin blood flow (SBF) and oxygen saturation (SO 2 ). Six amputees participated in this study. After 28 days of treatment, the PGE2 was significantly lower compared with that at day 0. The NPY was lower compared with that at day 0. The SBF and SO 2 change percentage in the intervention and recovery stages of each acupuncture treatment were all significantly increased. Moreover, the visual analog scale scores of PLP showed that patients felt their PLP disappeared completely and were satisfied with the acupuncture treatment. This study suggests that acupuncture was effective in treating PLP, and PGE2 and NPY may be regulators of pain transmission in PLP.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"323 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catgut Implantation at Acupoints has an Immunosuppressive Effect on Autoimmune Uveitis by Reducing Th1/Th17 Lymphocytes","authors":"Feifei Chen, Jianying Zhao, Shuyang Zhong, Fengming Zheng, Xiaobo Hao","doi":"10.3727/036012923x16800143458347","DOIUrl":"https://doi.org/10.3727/036012923x16800143458347","url":null,"abstract":"Catgut implantation at acupoints (CIA) has been applied as medical treatment for autoimmune diseases. Yet, its effect and mechanism of this therapy on autoimmune uveitis is still unknown. Here we aimed to explore the immunoregulatory effect of CIA in the experimental autoimmune uveitis (EAU) rat model. Lewis rats were induced with EAU by injecting IRBP1177 – 1191 peptide, and subsequently treated with CIA. In the CIA group, delayed mild inflammation was observed with alleviated infiltration of lymphocytes and ocular damage. Flow cytometry showed significant decrease in Th17 lymphocytes at Day 9, 13, and 18 post-immunizations ( P <0.05) after CIA. The Th1 lymphocytes were also significantly decreased at Day 13 and 18 post-immunizations ( P <0.05) in the CIA group. IL-17 and IFN- γ mRNA levels were notably decreased at Day 9, 13 and 18 post-immunizations (P <0.05) after CIA. Serum IL-17 and IFN- γ levels in the CIA group were significantly decreased at Day 9, 13 and 18 post-immunizations ( P <0.05). Ocular inflammation was markedly inhibited after catgut implantation at Pishu (BL20) and Shenshu (BL23) acupoints in the EAU-induced rats. In summary, this study revealed that CIA could reduce Th1 and Th17 lymphocytes and the expression of IFN- γ and IL -17 in the EAU rat model, suggesting its potential in uveitis treatment.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135289976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussion on the Theoretical Basis for Acupuncture to Improve Knee Osteoarthritis from \"Intestinal Microecology\"","authors":"Tian-Qi Wang, Ya-jie Wang, Si-Tong Xu","doi":"10.3727/036012921x16281724938195","DOIUrl":"https://doi.org/10.3727/036012921x16281724938195","url":null,"abstract":"The balance of the intestinal microecosystem is essentially consistent with the theory of \"Yin Ping Yang Mi\" in Chinese medicine. The imbalance of the intestinal microenvironment's homeostasis is closely related to the occurrence of diseases. Acupuncture and moxibustion can\u0000 improve the disease state by regulating the stability of the intestinal microecology, which has a certain theoretical basis. By exploring the law of the body's meridian circulation, it provides a theoretical basis for studying the regulation of acupuncture on the intestinal microecology of\u0000 patients with knee osteoarthritis (KOA).","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43339386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Electroacupuncture on Acupoints of Yanglingquan (GB34) on Gallbladder Volume and Gallbladder Arterial Hemodynamics in Patients With Chronic Cholecystitis","authors":"Hong-chun Zhang, Yi-Tong Wang, Zi-yang Cao","doi":"10.3727/036012921x16281724938122","DOIUrl":"https://doi.org/10.3727/036012921x16281724938122","url":null,"abstract":"Introduction: In China, patients with chronic cholecystitis account for approximately 10% of the total population, in which over 90% of cholecystitis is caused by cholelithiasis. This study aimed to discuss the possible mechanism of electroacupuncture on the Yanglingquan acupoint\u0000 promoting gallbladder contractibility of patients with chronic cholecystitis. Methods: 60 patients were randomly divided into a trial group and a control group. Doppler ultrasound and color Doppler blood flow imaging was applied. The trial group adopted the BT701-1B electroanesthesia\u0000 apparatus to perform electroacupuncture on the bilateral acupoints of Yanglingquan, while electroacupuncture was made on sham acupoints in the control group. Results: Before the electroacupuncture, gallbladder volume was 49.6 ± 5.66 ml, after 15 min and 30 min of electroacupuncture,\u0000 the gallbladder volume was then 32.9 ± 5.66 ml and 23.0 ± 2.83 ml respectively. The comparison before and after electroacupuncture was obviously and statistically different (P < 0.01). The comparison between after 15 min and 30 min is obviously statistically different (P <\u0000 0.01). Before the electroacupuncture, the gallbladder artery Vmax, Vmin, and RI were 18.4 ± 2.69 cm/s, 9.7 ± 0.07 cm/s, and 0.47 ± 0.06, respectively; the cystic artery Vmax, Vmin, and RI after 30 min were 8.1 ± 0.92 cm/s, 3.1 ± 0.57 cm/s, and 0.61 ±\u0000 0.02. The comparison in gallbladder artery Vmax and Vmin and the drag index (RI) before and after electroacupuncture was obviously and statistically different (P < 0.01). Conclusions: Electroacupuncture on the acupoints of Yanglingquan has the potential to promote the emptying of\u0000 the gallbladder. The mechanism may be related to that the smooth muscle of the gallbladder contracts after electroacupuncture and the gallbladder empties.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45773358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualized Analysis of Research Hotspots in Acupuncture-Neuro Immunoregulation Based on Bibliometrics","authors":"Tian-Qi Wang, Liming Sun, Le-Xin Hao, Yu Guo, Yue Zhang, Xin-xin Feng","doi":"10.3727/036012921x16281724938078","DOIUrl":"https://doi.org/10.3727/036012921x16281724938078","url":null,"abstract":"Objective: To review the development of acupuncture and moxibustion-neural network regulation research systematically and comprehensively in China. Method: This study adopted co-word analysis, cluster analysis and other bibliometric methods such as SATI3.2, Citespace and Gephi to visually\u0000 demonstrate the annual publication volume, cooperation between institutions and co-authorship in the field of acupuncture-neuro immunoregulation research based on the data of more than 70 papers on related topics covering a period of 24 years from 1997 to 2020 in China. Results: The results\u0000 show that there are three major research institutions in the field of acupuncture-neuro immunoregulation, namely Shanghai, Zhejiang major research institutions in the field of acupuncture-neuro immunoregulation, namely Shanghai, Zhejiang and Heilongjiang Universities of Traditional Chinese\u0000 Medicine, as well as 7 clusters, including immune function, acupuncture therapy and endogenous opioid peptide. In the future research, a more comprehensive system will be constructed based on the gradually clear relationship between meridians and nerve regulation, humoral regulation, and immune\u0000 regulation. Application practice will combine traditional acupuncture with modern medicine to create a variety of new therapies, such as electroacupuncture, electric acupuncture, and acupoint injection. Conclusion: The research focus will be expanded on how to improve the clinical efficacy\u0000 of multiple combined therapies such as acupuncture for the prevention and treatment of diseases through the regulation of immune cells and immune molecules as well as the regulation of the \"acupuncture-meridian- neuroendocrine-immune\" network.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47279064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Electroacupuncture Dilatational Wave Treatment of Acute-Stage Facial Paralysis","authors":"Qiong Chen, Fan-Rui Chen, Ya-Nan Li, Wan-Ting Bao, Hao Zhang","doi":"10.3727/036012921x16237619666085","DOIUrl":"https://doi.org/10.3727/036012921x16237619666085","url":null,"abstract":"Objective: To discuss and analyze the clinical efficacy and prognostic effect of an electroacupuncture dilatational wave in acute-stage facial paralysis. Method: Sixty patients with acute facial paralysis who received treatment in the inpatient department of our hospital from April 2018 to January 2019 were randomly divided into two groups: a treatment group and a control group. Both groups were treated with the same procedures, such as antivirus, nerve nutrition, circulation improvement, anti-inflammatory, infrared radiation on the affected side, electroacupuncture in quiescent period and Chinese herbal decoction. Dilatational wave treatment was also performed in the treatment group in the acute stage, and the clinical efficacy and effect on prognosis were compared between the two groups. Results: The total effective rate of the treatment group was 96.7%, and the total effective rate of the control group was 70%. The difference in the level of efficacy between the two groups was statistically different (P < 0.05). Conclusions: For the acute stage of facial paralysis, patients who underwent conventional treatment using an electroacupuncture dilatational wave showed a significantly improved efficacy rate, as well as other clear advantages. The treatment is, therefore, worthy of further investigation.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69698680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Stimulation of Front Tooth by Toothpick on Headache and Brain Tumor as well as other Malignant Tumors Malignant","authors":"Y. Omura","doi":"10.3727/036012921X16207330235365","DOIUrl":"https://doi.org/10.3727/036012921X16207330235365","url":null,"abstract":"It has been found that pain in various parts of the body can be temporarily eliminated by mechanically suppressing or stimulating the front tooth. Some typical examples of this are described in this article. We know which teeth represent which organs, but we also have diagrams that\u0000 show the cause of the pain, such as changes in certain areas of the electrocardiogram, and those possible areas are shown somewhere in the electrocardiogram. One minute downward pressure on the tip of any one of the front 3 teeth (1st incisor, 2nd incisor, and canine) at the right and left\u0000 sides of the upper and lower jaw by a wooden toothpick induced temporary disappearance (20 min-4 hours) of abnormally increased pain parameters (pain grading, Substance P, & TXB2), and cancer parameters (Telomere, Integrin α5 β1, Oncogene C-fos\u0000 Ab2, etc. of Astrocytoma, Glioblastoma, squamous cell carcinoma of esophagus, adenocarcinoma of lung, breast cancer, adenocarcinoma of colon, prostate cancer). The effect included temporary disappearance of headache, toothache, chest and abdominal pain, and backache, often with improved memory\u0000 & concentration. Since these beneficial changes resembled the effects of giving one optimal dose of DHEA, increase of DHEA was measured. Above mechanical stimulation of one of these front teeth increased abnormally reduced DHEA levels of less than 10 ng to normal 100–130 ng BDORT\u0000 units and normal cell (NC) telomeres from markedly reduced values to near normal values, and improved acetylcholine in the Hippocampus. Large organ representation areas for the Adrenal gland & Hippocampus may exist at these front teeth. This method can be used for emergency pain control\u0000 and can explain the beneficial effect of bruxism and tooth brushing, through the increase of DHEA levels and activities of the Hippocampus by increasing Acetylcholine. Increasing NC telomere to optimally high level resulted in disappearance of pain and improvement or significant reduction\u0000 of malignant tumor.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"46 1","pages":"239-245"},"PeriodicalIF":0.3,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45909258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture for Knee Osteoarthritis Based on Different Meridian Syndrome: A Randomized Controlled Pilot Trial","authors":"Tian-Qi Wang, Wan-Ting Lu, Jia Yang","doi":"10.3727/036012921X16207330235374","DOIUrl":"https://doi.org/10.3727/036012921X16207330235374","url":null,"abstract":"Background: We aimed to explore the feasibility of evaluating effectiveness and safety of electroacupuncture (EA) for the treatment of knee osteoarthritis (KOA) based on different meridian syndromes. Methods: A multicenter randomized controlled trial was conducted in Beijing\u0000 from January 2019 to December 2019. Sixty KOA participants were randomly allocated to either EA (n=30) or SA (n=30) groups. Participants in EA group were treated with semi-standardized on different meridian syndrome, including five obligatory acupoints and three adjunct acupoints. Eight non-acupoints\u0000 that were separated from conventional acupoints or meridians were used for the SA group. Both groups received 24 sessions within eight weeks. The primary outcome was response rate, defined as a change of ≥50% from baseline in total scores of Western Ontario and McMaster Universities osteoarthritis\u0000 index (WOMAC) at the end of treatment. Secondary outcomes included function, pain, stiffness, quality of life and acupuncture-related adverse events at four and eight weeks. Results: Of 60 participants randomized, 56 (93.3%) completed the study. Response rates were 60% for the EA group\u0000 and 30% for the SA group after eight weeks. Significant differences were observed in WOMAC pain and total scores within two groups (P =0.026, P =0.043). Rates of adverse events were low and similarly distributed between groups. Conclusion: EA intervention based on meridian\u0000 differentiation in KOA was feasible and appeared safe, having a stronger impact on pain than SA. Future studies can be designed with larger sample size, adequately powered, randomization design and less biases. Trial registration number: NCT03274713.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48083481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Acupoint Meridian Therapeutic Exercise on Cardiac Function in Patients with Chronic Heart Failure","authors":"Ting Hu, Haodengjie Xiong, Huilin Zhou, Yujie Song, Zhilin Zhang, J. Wan, Ping Tu, Xing-Lan Sun","doi":"10.3727/036012921X16207330235284","DOIUrl":"https://doi.org/10.3727/036012921X16207330235284","url":null,"abstract":"Objective: To investigate the effect of acupoint meridian therapeutic exercise on cardiopulmonary function in patients with chronic heart failure (CHF). Methods: One hundred patients diagnosed with CHF at the Department of Cardiology from June 2019 to October\u0000 2019 were enrolled. One hundred patients were randomly divided into an experimental group (n = 50) and a control group (n = 50) according to the treatment they received. The experimental group received conventional treatment combined with acupoint meridian therapeutic exercise for three months.\u0000 The patients in the two groups were compared in terms of their results on the six-minute walk test and their cardiac function grade, plasma brain natriuretic peptide (BNP) concentration, left ventricular ejection fraction (LVEF), and quality of life. Results: A statistically\u0000 significant increase in six-minute walking distance was observed in the experimental group compared with the control group. Cardiac function and plasma BNP concentration decreased and LVEF and quality of life increased. Conclusion: Acupoint meridian therapeutic exercise improves\u0000 exercise tolerance, cardiopulmonary function, and quality of life in patients with CHF.","PeriodicalId":50881,"journal":{"name":"Acupuncture & Electro-Therapeutics Research","volume":"46 1","pages":"177-189"},"PeriodicalIF":0.3,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43733267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}