针刺对幻肢痛患者血清及局部微循环生化指标的影响

IF 0.2 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture & Electro-Therapeutics Research Pub Date : 2023-08-17 DOI:10.3727/036012923x168667953174923

Hong mei Liu, Fan Yang, Ji wei Duan, Zeng yong Li, Hui qin Luan, Wei yan Ren

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引用次数: 0

摘要

幻肢痛(PLP)常见于截肢后患者。针刺治疗PLP可能有积极作用。本研究旨在观察针刺前后PLP患者血浆神经肽Y (NPY)和前列腺素E2 (PGE2)水平的变化，并通过测量皮肤血流量(SBF)和血氧饱和度(so2)来评价针刺对残肢外周循环的影响。6名截肢者参与了这项研究。治疗28 d后，PGE2较治疗0 d时明显降低。与第0天相比，NPY较低。各针刺治疗干预和恢复阶段的SBF和so2变化率均显著升高。此外，视觉模拟量表评分显示，患者感觉PLP完全消失，对针刺治疗感到满意。本研究提示针刺治疗PLP有效，PGE2和NPY可能是PLP疼痛传递的调节因子。

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Effect of Acupuncture on the Serum and Local Microcirculatory Biochemical Parameters in Phantom Limb Pain

Phantom limb pain (PLP) often occurs in post - amputation patients. Acupuncture may have a positive effect in treating PLP. This study aimed to observe the changes in plasma neuropeptide Y (NPY) and prostaglandin E2 (PGE2) levels before and after acupuncture in patients with PLP, and to evaluate the effects of acupuncture on the peripheral circulation of residual limbs by measuring the skin blood flow (SBF) and oxygen saturation (SO 2 ). Six amputees participated in this study. After 28 days of treatment, the PGE2 was significantly lower compared with that at day 0. The NPY was lower compared with that at day 0. The SBF and SO 2 change percentage in the intervention and recovery stages of each acupuncture treatment were all significantly increased. Moreover, the visual analog scale scores of PLP showed that patients felt their PLP disappeared completely and were satisfied with the acupuncture treatment. This study suggests that acupuncture was effective in treating PLP, and PGE2 and NPY may be regulators of pain transmission in PLP.

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来源期刊

Acupuncture & Electro-Therapeutics Research 医学-全科医学与补充医学

CiteScore

0.50

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.