{"title":"[Is positron emission tomography (PET) scan useful for studying the extent of gastrointestinal stromal tumors].","authors":"M J Molina Garrido, C Guillén Ponce","doi":"10.4321/s0212-71992007000600005","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600005","url":null,"abstract":"<p><p>Gastrointestinal tumor (GIST) is the most frequent mesenchymal malignancy of the gastrointestinal tract. Liver and peritoneum are the most frequent metastatic sites. Surgery is the standard treatment in patients with localized disease and imatinib mesylate has been shown to be an effective treatment in metastatic or unresectable disease. We present a case of ileal GIST that was diagnosed as metastatic just with the findings of the fluorodeoxyglucose positron emission tomography (PET) and showed a total response with Imatinib on PET.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"278-80"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Machado, Moix and Montalbán: smoke gets in your lives].","authors":"J Montes Santiago","doi":"10.4321/s0212-71992007000600010","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600010","url":null,"abstract":"<p><p>The writers Antonio Machado (pulmonary chronic disease), Terenci Moix (emphysema) and Manuel Vázquez Montalbán (acute myocardial infarction) died of the complications derived from their inveterate habit-forming tobacco. They were aware of the prejudices that a such addiction was causing and tried, in some moment, to leave it. In addition, the testimonies of their contemporary or their same writings offered dramatic samples of this struggle. Nevertheless, they relapsed and tobacco caused them a premature death before 65 years. With a panoramic of 60 years among the last two authors and Machado, a brief historical perspective is offered on the acquisition of scientific knowledge that changed the attitudes towards tobacco during this period of time.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"300-4"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gastroesophageal reflux as a cause of night sweating].","authors":"P Young, B C Finn, J E Bruetman, H Trimarchi","doi":"10.4321/s0212-71992007000600007","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600007","url":null,"abstract":"<p><p>Night sweats has been defined as drenching sweats that require the patient to change bed clothes. In current studies night sweats appear in 30% of non-obstetric patients and affects approximately 60% of pregnant women. Differential diagnoses include infections, malignancy, medications, hot flashes and panic attacks, making of each patient a challenge. We present two patients with night sweating. After excluding systemic diseases the diagnosis of gastroesophageal reflux was made, with excellent response to anti-reflux treatment. The presentation of our two patients coupled with a deep literature review, underscores the importance of gastroesophageal reflux as a cause of night sweating.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"285-8"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Cinza Sanjurjo, A Cabarcos Ortiz de Barrón, E Enrique Nieto Pol, J A Torre Carballada
{"title":"[Cross-sectional analysis of heart failure among patients in the Internal Medicine Service at a third-level hospital. Part I: epidemiologic analysis].","authors":"S Cinza Sanjurjo, A Cabarcos Ortiz de Barrón, E Enrique Nieto Pol, J A Torre Carballada","doi":"10.4321/s0212-71992007000600003","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600003","url":null,"abstract":"<p><strong>Objectives: </strong>To observe the epidemiologic characteristics of the patients intake during five years in a internal medicine department, with heart failure.</p><p><strong>Methods: </strong>A cross-sectional study of the intake patients in the Internal Medicine Service in the Hospital Clínico Universitario de Santiago de Compostela between 1999 to 2003. The variables analized were: sex, age, days of hospital stay, number of intake by failure cardiac, reason for admission (guide symptom), hypertension, diabetes mellitus, cardiac disease, fibrillation atrium, previous treatment with beta-blockers, blood pressure in the admission moment, to make echocardiography, disfunction systolic, etiology, deceased, treatment at the end. The statistical analysis was performed with qualitative and quantitative measures, chi-cuadrado and t-student, and multivariant analyses.</p><p><strong>Results: </strong>248 patients were accepted for the study. We observed more women than men (55.2%) and bigger median age (79 years old vs. 73 years old in men, p < 0.001). The mean income was 13.61 days and a median of 11 days. The 41,8% of the patients had hypertension, 30.9% diabetes mellitus and 81,9% had someone heart disease. The aetiologies of heart failure most frequent were ischemic cardiopathy (27.2%) and hypertension (24.2%). The most frequent symptom was the dyspnea (68.9%). It made echocardiography in 20.9% of patients and 45.1% showed systolic disfunction. The only factor related with this small percentage of echocardiographies was the incoming time. The most frequent etiology was respiratory infections (39.5%). The 8.6% of patients was deceased. The pharmacologic treatment more prescribed were the diuretics (86.9%) and transcutaneous nitrates (49.5%). It was indicated ECAI or AAR-II in the 86.9% of patients and beta-blockers in 0.9%.</p><p><strong>Conclusions: </strong>The number of echocardiograms practiced to the patients is smaller that the number advised by international associations and smaller to the cardiologist registers. The beta-blockers and ECAI use is smaller too.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"267-72"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Sánchez Beorlegui, R Cabezali Sánchez, E Monsalve Laguna, P Soriano Gil Albarellos, N Moreno de Marcos
{"title":"[New diagnostic and surgical approach to Mirizzi syndrome].","authors":"J Sánchez Beorlegui, R Cabezali Sánchez, E Monsalve Laguna, P Soriano Gil Albarellos, N Moreno de Marcos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mirizzi's syndrome is an unusual complication of gallstone disease, in which a stone impacting in the neck of the gallbladder (Hartmann s pouch) compresses the common bile duct. This mechanical obstruction leads to obstructive jaundice frequently followed by inflammatory changes and several complications. We present two patients affected by Mirizzi's syndrome whose diagnosis was correct in the preoperative period and approached by laparoscopy. A case was converted to open procedure due to adhesions in the Calot's triangle, and therefore, treated with subtotal cholecystectomy and choledochorrhaphy over a T tube. In the other case the laparoscopy access became successful. Both postoperative courses were uneventful. In this article, suitable diagnostic techniques are analyzed. On the other hand, we discuss what is the best therapeutic option, with a special attention to the relevance of endoscopic retrograde cholangiopancreatography and laparoscopic approach in the management of those patients.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"281-4"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A new therapeutic strategy in breast cancer: metronomic chemotherapy].","authors":"P Khosravi Shahi, G Pérez Manga","doi":"10.4321/s0212-71992007000600001","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600001","url":null,"abstract":"","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"261-2"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Martín Borge, L Herranz de la Morena, I Castro Dufourny, A Fernández Martínez, L F Pallardo Sánchez
{"title":"[Diabetic foot and risk factors].","authors":"V Martín Borge, L Herranz de la Morena, I Castro Dufourny, A Fernández Martínez, L F Pallardo Sánchez","doi":"10.4321/s0212-71992007000600002","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600002","url":null,"abstract":"<p><strong>Objective: </strong>To identify clinic and metabolic risk factors for diabetic neuropathy and peripheral arterial disease in patients evaluated in a diabetic foot unit care.</p><p><strong>Method: </strong>From 2000 to 2005 we evaluated the presence of diabetic neuropathy (monofilament, tuning fork and Boulton's clinic scale) and peripheral arterial disease (ankle-brachial index and toe-brachial index) in 304 diabetic patients. We classified patients in four groups: patients without pathology (normal group), with neuropathy (neuropathic group), with peripheral arterial disease (vascular group) and with both pathologies (mixed group) and we compared the characteristics of each group. We analysed other poblational characteristics: age, gender, type of diabetes, duration, microvascular and macrovascular complications, hypertension, smoking habit, antiagregation and mean HbA1c in the last year.</p><p><strong>Results: </strong>Age, frequency of hypertension and coronary disease were significantly higher (p < 0.005) in vascular and mixed group than in normal group (63 +/- 13 and 65 +/- 10 vs. 55 +/- 14; 69.2 and 70.3 vs. 45.5%; 46,2% and 39.2% vs 23.8%, respectively). Frequency of retinopathy, nephropathy and HbA1c were significantly higher (p < 0.05) in neuropathic and mix group than in normal group (62.5 and 66.2 vs. 32.7%; 45.3 and 47.3 vs. 24.8%; 8.1 +/- 1.6 and 8.0 +/- 1.3 vs 7.4 +/- 1.2 respectively).</p><p><strong>Conclusion: </strong>This study indicates that the development of diabetic neuropathy is related with worse metabolic control and the presence of other microvascular complications; while age, hypertension and coronary disease are risk factors for peripheral arterial disease.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"263-6"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J L Del Arbol, J Rico Irles, I Contreras, J C Aguirre, J Raya, M E Ruiz Requena, M T Miranda
{"title":"[Plasma concentrations of beta-endorphins in the children of alcoholic patients].","authors":"J L Del Arbol, J Rico Irles, I Contreras, J C Aguirre, J Raya, M E Ruiz Requena, M T Miranda","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Of the factors identified in different studies as the possible causes of alcoholism, heredity appears to be the most important. However, environmental factors can increase or decrease the risk of an individual developing alcohol dependence.</p><p><strong>Method: </strong>To clarify the possible influence of heredity on alcoholism, we studied the plasma concentration of beta-endorphins in 25 families with alcoholic members: 27 children whose father was alcoholic and 7 whose father and mother were both alcoholics. The results were compared with finding in an age-matched control group of no-drinking adults and normal children in non-drinking families.</p><p><strong>Results: </strong>The children of alcoholic parents had significantly lower beta-endorphin levels (p < 0.001) than control individuals, and concentrations were especially low when both parents were alcoholics.</p><p><strong>Conclusion: </strong>We conclude that plasma beta-endorphin concentration may have predictive value in identifying persons likely to become alcoholics.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"273-7"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Chlamydial infections].","authors":"B Roca","doi":"10.4321/s0212-71992007000600009","DOIUrl":"https://doi.org/10.4321/s0212-71992007000600009","url":null,"abstract":"<p><p>Chlamydiae are a singular group of bacteria, with a vital cycle that is intracellular in part. These microorganisms adhere to epithelia, where they may provoke infection. There are three pathogenic species for humans: Chlamydia trachomatis, which produce infections mainly in the genital and urinary tracts, and C. psittaci and C. pneumoniae, which mostly produce respiratory infections. The last two microorganisms are now classified in a different genus, known as Chlamydophila.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"292-9"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41005745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}