Anales De Medicina Interna最新文献

{"title":"[Mediastinal leiomyosarcoma].","authors":"B. C. Steen, S. Flórez Martín, L. Fernández Fáu, J. García Tirado, J. J. Jareño Esteban, J. Ancochea Bermúdez","doi":"10.32388/af52dw","DOIUrl":"https://doi.org/10.32388/af52dw","url":null,"abstract":"Primary mediastinal leiomyosarcomas are malignant sarcomas with unknown etiology not deriving from the smooth muscle fiber of the esophagus, trachea or main vessels. Very few cases have been reported in the literature and, although they are clinically unspecific, their histology is unique. The case described here is a 66-year-old woman with a leiomyosarcoma localized at the medium and posterior mediastinum, clinically presented as a mediastinal emergency.","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"10 2 1","pages":"83-5"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49188415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mantle cell lymphoma].","authors":"P. Khosravi Shahi, A. del Castillo Rueda, G. Pérez Manga","doi":"10.32388/a6i1f3","DOIUrl":"https://doi.org/10.32388/a6i1f3","url":null,"abstract":"Mantle cell lymphoma accounts for approximately 7% of adult Non-Hodgkin Lymphomas. It is a neoplasm of monomorphous small to medium-sized B cells with irregular nuclei. The tumor cells express strong IgM and IgD, and B-cell-associated antigens. Nuclear cyclin D1 protein is present in all cases and is the gold standard for the diagnosis. The t(11;14) (q13;q32) in the majority of the cases results in rearrangement of the BCL-1 locus and overexpression of the cyclin D1 gene. Most patients present with disseminated disease. Mantle cell lymphoma is an incurable neoplasm, but it may be treated with different chemotherapy regimen (R-Hyper-CVAD, R-CHOP, bortezomib) and young patients should be considered for high-dose therapy and autologous or allogeneic bone marrow transplantation.","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"24 3 1","pages":"142-5"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43076974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The neuroleptic malignant syndrome].","authors":"J. Garćia Castaño, M. García Román, B. Pinilla Llorente, C. Gilsanz Fernández","doi":"10.32388/bdk2dh","DOIUrl":"https://doi.org/10.32388/bdk2dh","url":null,"abstract":"Dear Editor, The clinical features of an uncommon hypersensitivity to neurolepitcs were first described by Preston, 1 and was subsequently known as neuroleptic malignant syndrome (NMS). The incidence of NMS report elsewhere is between 0.07% 2 7 and the mortality rate is up to 25%. 8, 9 The condition appears to be an idiosyncratic reaction to a therapeutic dose of the antipsychotic drugs especially dopamine receptor antagonists and a dose relationship has been postulated. 10, 11 Despite the sporadic occurrence of NMS in our psychiatric units, no case has been reported from Nigeria. A 21-year-old female nurse who was Gravida 1, Para 1+ developed acute postpartum psychosis of manic type, two days following childbirth. She developed the psychosis on a background of normal personality and absence of any family history of psychiatric or neurological illness. She was initially admitted at a general hospital, where she works. On admission, she was given massive dose of chlorpromazine and paraldehyde intramuscularly (the relations could not ascertain the amount of dosage given). On the third day of admission, she became more restless, confused, pyrexic and developed generalized stiffness. She was transferred to another hospital where a lumbar puncture was done to exclude meningitis, but the cerebrospinal fluid was normal. She was then referred for electroencephalogram (EEG) to exclude organic brain disease. By the time the patient was brought to the EEG clinic, her temperature was 42c and she had marked body rigidity of plastic type with occasional choreoform movement of the limbs and in addition was comatose. Pulse rate was 110 per minute, regular and normal volume and blood pressure 140/95mmHg. The EEG showed diffuse mixture of fast and slow waves and the background activity consisted of muscle artifact on all channels and NMS was suspected. Blood samples were taken for complete blood count, serum electrolytes and urea, liver function tests and serum creatine kinase. All neuroleptic drugs were discontinued and she was moved into an airconditioned room and tepid sponged with water. Bromocriptine was commenced (10mg 6 hourly) along with 10mg diazepam 6 hourly and benzhexol 5mg 8 hourly. All the medications were given intramuscularly for the first 48 hours and orally by nasogastric tube. By the second temperature dropped to 37.5c, blood pressure remained 140/90 mmHg and level of consciousness improved. By this time laboratory results became available; haemogram was 11.5g/dl, white cell count 11.3 x 10/L; serum sodium was 140mmol/l, potassium 6.0mmoI/l, urea 20mg%, aspertate transaminase 50 iu/l, erythrocyte sedimentation rate 22mm/hr and creatine kinase 3600 iu/l. On the 4 day, temperature was normal, and she could recognize familiar people and was able to speak. Her body rigidity became less and she was able to walk with some help. By the 7 day, the patient started becoming restless and talkative, as a result she was placed on thioridazine 100mg 12 hourly","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"6 10 1","pages":"552-3"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46921808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Microscopic polyarteritis].","authors":"C. L. de Ancos Aracil, J. R. Rebollar Mesa","doi":"10.1007/springerreference_39113","DOIUrl":"https://doi.org/10.1007/springerreference_39113","url":null,"abstract":"","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"12 9 1","pages":"456-60"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41708658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic fatigue syndrome","authors":"M. Garralda","doi":"10.1007/978-0-387-87687-0_21","DOIUrl":"https://doi.org/10.1007/978-0-387-87687-0_21","url":null,"abstract":"","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"7 1","pages":"285-295"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51700530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Efficiency profile in the neurological referrals effectuate reference specialists: use case-mix system adjusted clinical groups].","authors":"A. Sicras-Mainar, R. Navarro-artieda","doi":"10.1016/S1098-3015(10)66990-2","DOIUrl":"https://doi.org/10.1016/S1098-3015(10)66990-2","url":null,"abstract":"","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"117 1","pages":"213-21"},"PeriodicalIF":0.0,"publicationDate":"2008-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1098-3015(10)66990-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56757666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Standard error of measurement: an alternative to minimally important difference to access changes in patient-reported-health-outcomes].","authors":"J Rejas,&nbsp;M Ruiz,&nbsp;A Pardo","doi":"10.4321/s0212-71992007000900002","DOIUrl":"https://doi.org/10.4321/s0212-71992007000900002","url":null,"abstract":"<p><strong>Objective: </strong>To assess the concordance level between the standard Error of Measurement (EEM) and the minimal important difference (MID) criteria when evaluating the magnitude of change in self-perceived health status due to a clinical intervention.</p><p><strong>Method: </strong>Two scales of patient self-reported health are used [a measure of benign prostatic hyperplasia impact (BPH-PIM) and a life satisfaction scale (LISAT-8)] in two independent studies carried out in order to adapt each scale to Iberian Spanish population. These studies included 129 and 537 males with benign prostatic hyperplasia (BPH) and erectile dysfunction (ED), respectively. After computing EEM and MID values, patients where classified in three groups attending to each criterion: improvement, without change, and worsening. Cohen s kappa agreement index and Kendall s tau-b lineal correlation coefficient where used to assess the level of concordance between criteria.</p><p><strong>Results: </strong>The concordance level between EEM and MID criteria was found to be high for both scales: kappa agreement index attained values of 0.81 and 0.76, while tau-b correlation coefficient attained values of 0.87 and 0.79.</p><p><strong>Conclusion: </strong>The agreement level found allows to state that the EEM criterion is an adequate alternative to the MID criterion when assessing the magnitude of change produced in patient reported health.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"415-20"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41067693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Using patient report outcomes in the office: a challenge for the physician].","authors":"E Rey","doi":"10.4321/s0212-71992007000900001","DOIUrl":"https://doi.org/10.4321/s0212-71992007000900001","url":null,"abstract":"","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"413-4"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41066642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pluriglandular autoimmune syndrome. Systematic review].","authors":"M J Molina Garrido,&nbsp;C Guillén Ponce,&nbsp;M Guirado Risueño,&nbsp;A Mora,&nbsp;A Carrato","doi":"10.4321/s0212-71992007000900009","DOIUrl":"https://doi.org/10.4321/s0212-71992007000900009","url":null,"abstract":"<p><p>There are a lot of autoimmune syndromes with glandular disfunction which are associated to another diseases. Sometimes, these processes are associated to similar cases in the same family. Autoimmune polyglandular syndromes are characterized by the coexistence of two or more endocrine insufficiencies due to an autoimmune mechanism: the activity of autoantibodies or T activated lymphocytes against organs or endocrine glands. In this report, they have been described the main autoimmune syndromes, the diagnostic methods and the mechanisms which take a role in their origin.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"445-52"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41067094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Neurological manifestations as presentation of infectious endocarditis].","authors":"J F Varona","doi":"10.4321/s0212-71992007000900007","DOIUrl":"https://doi.org/10.4321/s0212-71992007000900007","url":null,"abstract":"<p><p>Neurologic complications of infective endocarditis (IE) are frequent. In many cases, they are the initial feature and considerably impair the prognosis of the disease. The most common neurologic manifestation is embolic stroke, but other many neurologic events have been described, ranged from cerebral hemorrhage due to rupture of mycotic aneurysm to the exceptional aseptic meningitis with acellular cerebrospinal fluid. We describe 3 cases that represent this wide spectrum of presentation. Ischemic stroke in the first patient and cerebral hemorrhage in the second were respectively documented several days before the diagnosis of IE. In the third case, acellular meningitis was the unusual clinical debut of aortic IE. Cerebral infarct or hemorrhage are exceptionally caused by an underlying IE, so a high level of suspicious is needed to recognize these complications. The best management to improve the prognosis has to be based on a rapid diagnosis and onset of antibiotic treatment, considering valve replacement in the adequate timing.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":" ","pages":"439-41"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41067698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}