Annals of Allergy Asthma & Immunology最新文献

{"title":"Mental health for the allergist","authors":"Timothy M. Buckey MD, MBE , Jonathan M. Spergel MD, PhD","doi":"10.1016/j.anai.2025.03.004","DOIUrl":"10.1016/j.anai.2025.03.004","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 497-498"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomics","authors":"Sophia Linton BSc , Anne K. Ellis MD, MSc","doi":"10.1016/j.anai.2025.02.002","DOIUrl":"10.1016/j.anai.2025.02.002","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 502-503"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the pages of AllergyWatch","authors":"Stanley M. Fineman MD , Shyam R. Joshi MD , Sarah Spriet DO , Vivian Hernandez-Trujillo MD","doi":"10.1016/j.anai.2025.02.008","DOIUrl":"10.1016/j.anai.2025.02.008","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 619-620"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S1081-1206(25)00170-X","DOIUrl":"10.1016/S1081-1206(25)00170-X","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Page A5"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes and variation in management of penicillin allergy in pregnant patients presenting for prenatal care","authors":"Victoria T. Nguyen DO , Mitchell Shelton MD , Monica T. Kraft MD","doi":"10.1016/j.anai.2025.02.014","DOIUrl":"10.1016/j.anai.2025.02.014","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 610-611"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thinking like a Bayesian: Diagnostic food allergy testing at the extremes of clinical certainty","authors":"Marcus S. Shaker MD, MS , Aikaterini Anagnostou MD, PhD , Matthew Greenhawt MD, MBA, MSc , Benjamin T. Prince MD, MSCI , Kristin Sokol MD, MS, MPH","doi":"10.1016/j.anai.2024.11.027","DOIUrl":"10.1016/j.anai.2024.11.027","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 504-505"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mannitol provocation enhances laryngoscopic diagnosis of suspected inducible laryngeal obstruction","authors":"Stephanie Stojanovic MBBS ,&nbsp;Asger Sverrild PhD, MD ,&nbsp;Tunn Ren Tay MRCP ,&nbsp;Eve Denton PhD, MPH ,&nbsp;Kavitha Garuna Murthee MBBS, MRCP ,&nbsp;Tiffany Lin MBBS ,&nbsp;Logan Gardner MBBS ,&nbsp;Melanie Wong MBBS ,&nbsp;Brigitte Borg BAppSc ,&nbsp;Janine Mahoney B Speech Pathology ,&nbsp;Joy Lee PhD ,&nbsp;Mark Hew PhD, MSc","doi":"10.1016/j.anai.2025.02.001","DOIUrl":"10.1016/j.anai.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Inducible laryngeal obstruction (ILO) is confirmed by observing paradoxical vocal fold movement (PVFM) on laryngoscopy, but test sensitivity is reduced by its intermittent nature. Specificity of isolated expiratory PVFM is also unclear, possibly denoting a physiological response to lower airway obstruction.</div></div><div><h3>Objective</h3><div>To clarify laryngoscopic diagnosis in suspected ILO through mannitol provocation.</div></div><div><h3>Methods</h3><div>In patients with suspected ILO, we assessed rates of laryngoscopic PVFM, both at baseline and after mannitol provocation, defined as any inspiratory adduction, more than or equal to 50% expiratory adduction, or both. We also studied accentuation of laryngoscopic findings after mannitol provocation, defined as new or increased PVFM. We explored relationships between isolated expiratory PVFM, lower airway obstruction on spirometry, and bronchial hyperresponsiveness to mannitol. We also studied healthy volunteers.</div></div><div><h3>Results</h3><div>Among 80 patients with suspected ILO, PVFM rates were 42 (52.5%) at baseline and 58 (72.5%) after mannitol. Mannitol accentuated laryngoscopic findings in 45 of 80 (56%), with new PVFM in 17 of 80 (21%) and increased PVFM in 28 of 80 (35%) and 28 of 42 (67%) of patients with PVFM at baseline. Among patients with baseline isolated expiratory PVFM, 21 of 30 had accentuation by mannitol and there was no relationship with airway obstruction or bronchial hyperresponsiveness. Among healthy volunteers, PVFM rates were identical at baseline and after mannitol (4/15, 27%, all 4 with isolated expiratory PVFM); none (0/15) had accentuation by mannitol.</div></div><div><h3>Conclusion</h3><div>Accentuation of laryngoscopic findings after mannitol provocation is more useful than PVFM at baseline laryngoscopy in distinguishing patients with suspected ILO from healthy volunteers. Isolated expiratory PVFM without accentuation by mannitol can be a normal finding and unrelated to bronchial obstruction or hyperresponsiveness.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 563-569"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing childhood asthma with an eye toward environmental, social, and behavioral features","authors":"Emily H. Skeen MD,&nbsp;Katharine L. Hamlington PhD,&nbsp;Heather H. De Keyser MD,&nbsp;Andrew H. Liu MD,&nbsp;Stanley J. Szefler MD","doi":"10.1016/j.anai.2025.02.013","DOIUrl":"10.1016/j.anai.2025.02.013","url":null,"abstract":"<div><div>Discussions on asthma management tend to focus on the therapeutic aspects when updates on asthma strategies are released. However, many other components of asthma management are now receiving increased attention, as we seek to make right on health disparities and strive toward health equity. In addition, with the therapeutic aspects of asthma, we now realize that our anti-inflammatory approaches largely address the high T2 component of airway inflammation. However, we know very little about what we can do to control the other inflammatory features that contribute to asthma. Factors, such as environmental exposures, social determinants of health, and risk-taking behaviors may be at the root of asthma persistence, progression, and comorbidities. We will continue to learn methods to identify these issues and draw them into a shared decision-making approach for dialogue with patients and their caregivers. This review provides information and tools to address the nonpharmacologic aspects of asthma management.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 516-524"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Want to help your patients with food allergy anxiety? Do proximity challenges!","authors":"Katherine K. Dahlsgaard PhD, ABPP ,&nbsp;Megan O. Lewis MSN, RN, CPNP-PC","doi":"10.1016/j.anai.2025.02.020","DOIUrl":"10.1016/j.anai.2025.02.020","url":null,"abstract":"<div><div>Excessive anxiety regarding the potential for accidental and fatal cross-contamination is very common among patients and families with food allergy and contributes significantly to burden, reduced quality of life, and poorer management. In their landmark paper published nearly a decade ago, Dr Chitra Dinakar and colleagues recommended that food allergists incorporate proximity food challenges such as smelling or touching an allergen into regular clinical practice to improve patient knowledge regarding safety and relative risk and reduce anxiety. Such proximity challenges are akin to the exposure tasks routinely used to treat anxiety in cognitive-behavioral therapy, the first-line psychosocial intervention for anxiety disorders. Exposure is a highly evidence-based therapy technique in which patients—guided and encouraged by their providers—directly and strategically confront a feared object, situation, or activity. Anxiety eventually diminishes and erroneous beliefs are corrected when exposures happen repeatedly in the absence of the feared negative outcome. Following a summary of the history and evidence base for exposure in both the psychiatric and food allergy literature, we review several considerations related to conducting in-office proximity challenges. Topics include in-office assessment of food allergy anxiety and medically unnecessary avoidance; choosing appropriate, individualized proximity challenges based on patient presentation; and practical considerations in carrying out in-office proximity challenges to maximize benefits to anxious patients.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Pages 525-532"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"10 ways to improve …","authors":"Mitchell H. Grayson MD","doi":"10.1016/j.anai.2025.01.023","DOIUrl":"10.1016/j.anai.2025.01.023","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"134 5","pages":"Page 499"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}