Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)最新文献

{"title":"DIABETES MELLITUS A RISK FACTOR OF GASTRIC CANCER : SYSTEMATIC REVIEW","authors":"Mohamad Azwar Aziz, Yulia Intan Kania, Ilham Aziz, Sibli","doi":"10.61841/cbs35v81","DOIUrl":"https://doi.org/10.61841/cbs35v81","url":null,"abstract":"Background: It is estimated that 500 million individuals globally would have diabetes mellitus (DM) by 2030. A deadly tumor that affects the digestive tract is called gastric cancer (GC). It ranks as the fourth leading cause of cancer death worldwide and the fifth most common kind of cancer. Every year, there are around 700,000 fatalities and one million new cases of GC globally.\u0000Aims : This systematic review is to review the association of diabetes mellitus as a risk factor of gastric cancer.\u0000Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. \u0000Result: In the PubMed database, the results of our search brought up 343 articles, whereas the results of our search on SAGEPUB brought up 2178 articles, our search on SCIENCE DIRECT brought up 23102 articles. The results of the search conducted for the last year of 2014 yielded a total 231 articles for PubMed, 1017 articles for SAGEPUB and 12260 articles for SCIENCE DIRECT. In the end, we compiled a total of  5 papers, 2 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included five research that met the criteria.\u0000Conclusion: In summary, there is no direct association of diabetes mellitus and gastric cancer, but diabetes mellitus can increase the risk factor of gastric cancer cases.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"333 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140247081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LONG-TERM RISK OF CHRONIC AND END-STAGE KIDNEY DISEASE AFTER PREECLAMPSIA: SYSTEMATIC REVIEW","authors":"Mohamad Azwar Aziz, Yulia Intan Kania, Ilham Aziz, Sibli","doi":"10.61841/jrq5ca91","DOIUrl":"https://doi.org/10.61841/jrq5ca91","url":null,"abstract":"Introduction: Preeclampsia (PE) is a pregnancy-related syndrome, and its diagnosis has evolved to consider factors like hypertension and kidney involvement, with serum creatinine gaining importance. Despite the traditional view of PE as transient and reversible kidney disease, recent studies link it to long-term risks, including cardiovascular and renal diseases. The systematic review, \"Long-Term Risk of Chronic and End-Stage Kidney Disease After Preeclampsia,\" aims to gather updated information from recent studies, focusing on ESRD, CKD, and kidney-related morbidity after PE. The goal is to inform the formulation of effective long-term control and prevention strategies for CKD associated with a history of preeclampsia. \u0000Method: The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research. \u0000Result: This systematic review investigated final 16 articles. After looking at the titles and summaries, we found 8  papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included a nation-wide cohort, nationwide register based cohort study, observational cohort study, population-based nested case-control study, and longitudinal cohort study. \u0000Conclusion: Our study reveals a significant long-term impact of preeclampsia on kidney health, with a 5-fold higher risk of end-stage kidney disease (ESKD) for affected women. Ongoing clinical monitoring and further research are crucial to identify high-risk individuals, understand underlying mechanisms, and establish optimal follow-up and intervention strategies.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATION OF OXIDATIVE STRESS BIOMARKERS MDA AND SOD IN OCCUPATIONALLY EXPOSED ALUMINUM WORKERS IN ONITSHA, ANAMBRA STATE, NIGERIA","authors":"C.A Okechukwu, A. N. Okpogba, N. A. Mbachu, I.P Ezeugwunne","doi":"10.61841/3qtqvw39","DOIUrl":"https://doi.org/10.61841/3qtqvw39","url":null,"abstract":" Aim: This research study was conducted to evaluate oxidative stress biomarkers using malondialdehyde (MDA) and superoxide dismutase (SOD) in aluminum workers exposed to occupational hazards.\u0000 \u0000Research Method: The participants were recruited from an industrial area in Onitsha and divided into two groups: an exposure group composed of workers occupationally exposed to aluminum and a control group without exposure. The method of Gutteridge and Wilkins, (1982) was used for the estimation of malondialdehyde levels. SOD activity was measured according to the method as described by Misra and Fridovich, 1972. Data were analyzed using SPSS version 25 (IBM, USA, 2018). Independent T-test, descriptive, statistics, and Spearman correlation were used to analyze the data.\u0000 \u0000Results: The results showed a significant increase in MDA in the aluminum workers group (3.53±1.04) as compared to the control group (1.65±0.58) (p<0.005). The SOD levels were reduced in the aluminum workers (21.55±3.85) as compared with the control samples (24.12±3.54) (p<0.005), indicating an elevation of oxidative stress. The study results revealed a significant positive correlation between MDA levels, age and duration of exposure. The SOD levels revealed a nonsignificant negative correlation with age and a significant correlation with duration of exposure.\u0000 \u0000Conclusion: The findings indicate that long-term occupational exposure to aluminum can lead to increased oxidative stress, as indicated by higher MDA levels and lower SOD levels ","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"32 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140249799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIAGNOSTIC IMAGING OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A TEN YEARS SYSTEMATIC REVIEW","authors":"Rezeki Hayati, Rian Candra","doi":"10.61841/k8w3ww68","DOIUrl":"https://doi.org/10.61841/k8w3ww68","url":null,"abstract":"Background: Exacerbations of chronic obstructive pulmonary disease (COPD) impose a great burden on patients’ quality of life and healthcare systems. In addition to causing significant increases in mortality and disease progression, exacerbations of COPD amount to $18 billion in direct costs annually, as well as further spending associated with care and losses in productivity. Newer modalities such as OCT and MRI have distinct advantages to CT in such areas as image resolution and functional assessment of lung tissue. \u0000The aim: The aim of this study to show about diagnostic imaging of chronic obstructive pulmonary disease. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search get 100 articles, whereas the results of our search on SagePub get 1608 articles, on Google Scholar 3870 articles. Records remove before screening are 4887, so we get 691 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. \u0000Conclusion: Imaging and image analysis offers new insight into pulmonary disease processes that were previously available only on tissue necropsy. Current techniques can offer detailed measures of lung structure and with newer modalities previously immeasurable things like regional lung function. Imaging in the context of clinical investigation may offer the ability to define more homogeneous subsets of subjects with COPD and to potentially provide an intermediate biomarker of disease progression in lieu of a declining FEV.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"9 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CORTICOSTEROID AND LIDOCAIN INJECTION FOR TREATMENT OF HIP OSTEOARTHRITIS : AN UPDATE SYSTEMATIC REVIEW","authors":"M. Y. Hardiyansah, Yosie Yulanda Putra, Ahsan Auliya","doi":"10.61841/hq1qch52","DOIUrl":"https://doi.org/10.61841/hq1qch52","url":null,"abstract":"Background:  Intraarticular corticosteroid injections (ICSI) can relieve pain in patients with symptomatic osteoarthritis (OA) for weeks. A recent randomized controlled trial showed superior pain improvement following ICSI compared to treatment without injection over a period of 6 months. Atchia et al. compared ICSI to saline-injection and treatment without injection and found ICSI to be the only treatment resulting in significant improvement in both pain and function. \u0000The aim: The aim of this study to show about corticosteroid and lidocaine injection for treatment of hip osteoarthritis. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search get 7 articles, whereas the results of our search on SagePub get 6 articles, on Google Scholar 1690 articles. Records remove before screening are 1438, so we get 265 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. \u0000Conclusion: Ultrasound guided intra-articular hip injection of corticosteroid and local anaesthetic, administered with advice and education, is a clinically effective treatment for rapid and sustained symptom response compared with advice and education alone for people with hip osteoarthritis. These findings provide evidence to inform international guidelines and support treatment decision making for policy makers, payers (commissioners), GPs, and clinicians in musculoskeletal services.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"180 s460","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RISK SCORE PREDICTION MODEL FOR DEMENTIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS : AN UPDATE SYSTEMATIC REVIEW","authors":"Suwandhi, Ayyub","doi":"10.61841/7tzs2y21","DOIUrl":"https://doi.org/10.61841/7tzs2y21","url":null,"abstract":"Background: Dementia is a substantial global health issue. Reduction in future numbers of dementia cases through effective preventive strategies could significantly affect the personal and socioeconomic burdens of dementia. WHO has recommended that countries urgently develop national public health programmes to reduce the impact of dementia. \u0000The aim: The aim of this study to show about risk score prediction model for dementia in patients with type 2 diabetes mellitus. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search get 67 articles, whereas the results of our search on SagePub get 210 articles, on Google Scholar 1350 articles. Records remove before screening are 667, so we get 960 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. \u0000Conclusion: RxDx-Dementia risk index to predict dementia in patients with type 2 diabetes and hypertension. The RxDx-Dementia risk index which incorporated diagnosis and prescription-based information in a single summary score performed better than diagnosis- or prescription-based comorbidity scores or its combinations. The RxDx-Dementia risk index can be used for prognostic purpose or to control confounding in epidemiological studies.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"271 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TREATMENT OF OSTEOARTHROTIS OF THE KNEE : SYSTEMATIC REVIEW","authors":"M. Y. Hardiyansah, Yosie Yulanda Putra, Ahsan Auliya","doi":"10.61841/ne325a76","DOIUrl":"https://doi.org/10.61841/ne325a76","url":null,"abstract":"Background: Osteoarthritis (OA) of the knee, also referred to as degenerative joint disease of the knee, is usually caused by gradual articular cartilage loss as well as wear and tear. Seniors are more likely to experience it.\u0000Aims : This systematic review is to review the effect and efficacy of the therapy of knee osteoarthritis.\u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, ScienceDirect and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 36.803 articles, whereas the results of our search on SAGEPUB brought up 10.021 articles, our search on SCIENCE DIRECT brought up 51.811 articles. The results of the search conducted for the last year of 2014 yielded a total 22.949 articles for PubMed, 6.322 articles for SAGEPUB and 28.399 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 2 of which came from PubMed, 2 of which came from SAGEPUB and 4 of which came from SCIENCE DIRECT. We included eight research that met the criteria.\u0000Conclusion: In summary, although we discovered that several treatments worked, we were unable to rate the effects since the network as a whole lacked coherence and strong confidence in the treatment comparisons.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"192 S545","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRACTICAL ASPECT OF NUTRITIONAL SUPPORT FOR WOUND-HEALING PATIENTS : A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Atep L Pahlepi, Evan Wahyudy Ladala","doi":"10.61841/hesne917","DOIUrl":"https://doi.org/10.61841/hesne917","url":null,"abstract":"Background: The skin is the largest organ system whose primary function is to serve as a barrier to protect the body against foreign microbes and noxious substances. Skin integrity and function require macro and micronutrients for cell turnover to maintain homeostasis, and support new growth, and repair, especially in the event of injury or decreased integrity. Wound healing is an important focus of care across all settings, not limited to any particular condition or age group. Achieving optimal healing requires an understanding of nutritional requirements, and these need to be adapted to the setting and incorporated into a care plan. \u0000The aim: The aim of this study to show about practical aspect of nutritional support for wound healing patients. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed databasethe results of our search get 40 articles, whereas the results of our search on SagePub get 448 articles, on Google Scholar 4060 articles. Records remove before screening are 3376, so we get 1172 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. \u0000Conclusion: Nutrition is influential in wound healing, and some key nutrients extend their benefits to aesthetic outcomes. Several studies have shown associations between nutritional deficits and suboptimal wound healing outcomes. However, the current corpus of evidence remains rather generalized. ","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"218 S705","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NONSURGICAL RHINOPLASTY: SYSTEMATIC REVIEW","authors":"Shabrina Nur Afiati, Natalia Wijaya, Dini Marini","doi":"10.61841/snkj2d77","DOIUrl":"https://doi.org/10.61841/snkj2d77","url":null,"abstract":"Introduction: The surge in demand for nonsurgical rhinoplasty, driven by patients seeking alternatives to the enduringly popular surgical rhinoplasty, emphasizes the need for skilled facial plastic surgeons proficient in filler placement. Offering nonsurgical rhinoplasty by experienced surgeons enhances safety, contributes to surgical practice success, and serves as a cost-effective, low-risk alternative, especially when patients are considering future surgery. Systematic reviews play a crucial role in consolidating evidence, informing practitioners about the latest developments, and establishing best practices in both nonsurgical and surgical rhinoplasty, contributing to improved patient care. \u0000Methods: The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research. \u0000Results: Our search produced 22 results. After looking at the titles and summaries, we found 10  papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included a retrospective analysis, observational study, and retrospective analysis of a prospective clinical registry. \u0000Conclusion: In conclusion, nonsurgical rhinoplasty, exemplified by a 14-year case series, is a highly gratifying and popular procedure, emphasizing an ascending technique for optimal outcomes. However, its potential complications necessitate experienced practitioners, urging caution and diligence. The systematic review supports the efficacy and safety of nonsurgical rhinoplasty using PDO sutures and fillers, especially in Asians, while emphasizing the importance of patient selection. Furthermore, the described \"LG Nose Reshaping Technique\" with hyaluronic acid proves safe and effective, warranting long-term studies, and the use of VYC-25L showcases high patient satisfaction and low adverse events when administered by skilled practitioners with optimized fillers.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"25 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140258519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIAGNOSIS AND TREATMENT OF STATUS EPILEPTICUS : AN UPDATE SYSTEMATIC REVIEW","authors":"Asmaul Husna, Sarah Annisa Hasanah","doi":"10.61841/gdrmpz79","DOIUrl":"https://doi.org/10.61841/gdrmpz79","url":null,"abstract":"Background: Status epilepticus (SE) is a condition resulting from the failure of the mechanisms involved in termination or the initiation of mechanisms responsible for seizure prolongation. \u0000The aim: The aim of this study to show about diagnosis and treatment of status epilepticus. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search get 110 articles, whereas the results of our search on SagePub get 163 articles, on Google Scholar 8200 articles. Records remove before screening are 7182, so we get 2761 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. \u0000Conclusion: There are increasingly more drug options to treat SE, but rational polytherapy should consider the pharmacodynamics and kinetics of established and new antiepileptic drugs. When seizures cannot be controlled with conventional medical therapy, non-conventional treatments, including early surgical evaluation can be considered; however, high-quality evidence for these strategies are lacking. Neurointensivists are challenged to reduce secondary brain injury by managing common complications.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"36 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}