Behavioural Neurology最新文献

{"title":"Oral Administration of Lactobacillus Inhibits the Permeability of Blood-Brain and Gut Barriers in a Parkinsonism Model","authors":"Angélica Y. Nápoles-Medina, Blanca R. Aguilar-Uscanga, Josué R. Solís-Pacheco, Aldo R. Tejeda-Martínez, Luis J. Ramírez-Jirano, María F. Urmeneta-Ortiz, Veronica Chaparro-Huerta, Mario E. Flores-Soto","doi":"10.1155/2023/6686037","DOIUrl":"https://doi.org/10.1155/2023/6686037","url":null,"abstract":"It has recently been shown that the administration of probiotics can modulate the microbiota-gut-brain axis and may have favorable effects in models of Parkinson’s disease. In this study, we used a hemiparkinsonism model induced by the neurotoxin 6-OHDA to evaluate the efficacy of the administration of a four-week administration of a mixture containing the microorganisms Lactobacillus fermentum LH01, Lactobacillus reuteri LH03, and Lactobacillus plantarum LH05. The hemiparkinsonism model induced an increase in rotations in the apomorphine test, along with a decrease in the latency time to fall in the rotarod test on days 14 and 21 after surgery, respectively. The administration of probiotics was sufficient to improve this condition. The model also showed a decrease in tyrosine hydroxylase immunoreactivity in the striatum and the number of labeled cells in the substantia nigra, both of which were counteracted by the administration of probiotics. The permeability of the blood-brain barrier was increased in the model, but this effect was reversed by the probiotics for both brain regions. The gut barrier was permeated with the model, and this effect was reversed and dropped to lower levels than the control group after the administration of probiotics. Finally, lipid peroxidation showed a pattern of differences similar to that of permeabilities. The inhibition of the permeability of the blood-brain and gut barriers mediated by the administration of probiotics will likely provide protection by downregulating oxidative stress, thus affecting the rotarod test performance.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":" 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135192740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of the Amharic Version of Self-Efficacy and Outcome Expectancy Measures on Intention to Take Preventive Actions on Noncommunicable Disease.","authors":"Shumye Molla Legesse, Habtamu Wondimu","doi":"10.1155/2023/6669157","DOIUrl":"10.1155/2023/6669157","url":null,"abstract":"<p><p>This study is aimed at developing and accessing the validity and reliability of an Amharic version of the self-efficacy and outcome expectancy measures on noncommunicable disease prevention strategies. The intentions to take protective measures on NCDs' self-efficacy and outcome expectancy scales were created in Amharic using a sequential nine-step process that included translation and contextualization of the items, content validity, pretesting of the questions, sampling, and survey administration. Principal component analysis was conducted on 829 university students which showed a one-factor solution for self-efficacy and a three-factor solution for outcome expectancy scales using split-half measures. Confirmatory factor analyses supported the factor structure, which also demonstrated good internal consistency (.828 self-efficacy, .766 outcome expectancy). The scales had a moderate level of correlation (<i>r</i> = .35, <i>p</i>.001) between them. The study resulted in reliable and valid Amharic versions of self-efficacy (9-item) and outcome expectancy (12-item) scales.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"6669157"},"PeriodicalIF":2.8,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71523299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging Therapeutic Potential of Cannabidiol (CBD) in Neurological Disorders: A Comprehensive Review.","authors":"Kuldeep Singh, Bharat Bhushan, Dilip Kumar Chanchal, Satish Kumar Sharma, Ketki Rani, Manoj Kumar Yadav, Prateek Porwal, Shivendra Kumar, Ashwani Sharma, Tarun Virmani, Girish Kumar, Abdullah Al Noman","doi":"10.1155/2023/8825358","DOIUrl":"10.1155/2023/8825358","url":null,"abstract":"<p><p>Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its potential therapeutic applications. This thorough analysis explores the increasing significance of CBD in treating neurological conditions including epilepsy, multiple sclerosis, Parkinson's disease, and Alzheimer's disease, which present major healthcare concerns on a worldwide scale. Despite the lack of available therapies, CBD has been shown to possess a variety of pharmacological effects in preclinical and clinical studies, making it an intriguing competitor. This review brings together the most recent findings on the endocannabinoid and neurotransmitter systems, as well as anti-inflammatory pathways, that underlie CBD's modes of action. Synthesized efficacy and safety assessments for a range of neurological illnesses are included, covering human trials, in vitro studies, and animal models. The investigation includes how CBD could protect neurons, control neuroinflammation, fend off oxidative stress, and manage neuronal excitability. This study emphasizes existing clinical studies and future possibilities in CBD research, addressing research issues such as regulatory complications and contradicting results, and advocates for further investigation of therapeutic efficacy and ideal dose methodologies. By emphasizing CBD's potential to improve patient well-being, this investigation presents a revised viewpoint on its suitability as a therapeutic intervention for neurological illnesses.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"8825358"},"PeriodicalIF":2.7,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Posttraumatic Stress Disorder Checklist among the Lebanese Population Exposed to the Beirut Explosion: A Cross-Sectional Study during the COVID-19 Pandemic.","authors":"Fadwa Alhalaiqa,&nbsp;Othman A Alfuqaha,&nbsp;Rami Masa'Deh,&nbsp;Anas H Khalifeh,&nbsp;Mahmoud Alsaraireh,&nbsp;Natija S Manaa,&nbsp;Osama Alkouri,&nbsp;Omar Al Omari","doi":"10.1155/2023/9286562","DOIUrl":"10.1155/2023/9286562","url":null,"abstract":"<p><strong>Objective: </strong>This study was aimed at testing the psychometric properties of the posttraumatic stress disorder (PTSD) checklist for the Diagnostic Statistical Manual version 5 (DSM-5) (PCL-5) among the Lebanese population and at identifying the prevalence of PTSD.</p><p><strong>Design: </strong>A cross-sectional survey of PCL-5 among 950 Lebanese, using the online survey platform by Google Form, was conducted. Snowball recruitment was used to identify participants for the survey.</p><p><strong>Results: </strong>Face, content, construct, discriminant, and convergent validity had been accomplished through the survey. The reliability using Cronbach's alpha, composite, and average variance extracted was identified as superior. We also found that more than half of the participants (55.6%) scored 33 or above which is the cut-off score for a likely diagnosis of PTSD.</p><p><strong>Conclusion: </strong>The current study provides further support for the validity and reliability of the Arabic version of PCL-5 among non-Western populations. This supports using the checklist in the screening of probable PTSD.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"9286562"},"PeriodicalIF":2.8,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smaller and Denser Speech Graphs in Nondemented Patients with Progressive Supranuclear Palsy.","authors":"Jinghong Ma,&nbsp;Guanyu Zhang,&nbsp;Xiaomin Sun,&nbsp;Piu Chan,&nbsp;Zheng Ye","doi":"10.1155/2023/3771601","DOIUrl":"10.1155/2023/3771601","url":null,"abstract":"<p><p>The well-established semantic fluency test measures the ability to produce a sequence of spoken words from a particular category within a limited period of time. Like patients with Parkinson's disease (PD), patients with progressive supranuclear palsy (PSP) tend to produce fewer correct words than age-matched healthy adults. This study further examined the difference between patients with PSP and PD in their semantic fluency performance using a graph theory-based approach. Twenty-nine patients with PSP Richardson's syndrome (PSP-RS), thirty-eight patients with PD, and fifty-one healthy controls (HC) were recruited. All participants completed a standard semantic fluency test (animals). Their verbal responses were recorded, transcripted, and transformed into directed speech graphs. The speech graphs of the PSP-RS group showed higher density, shorter diameter, and shorter average shortest path than those of the PD and HC groups. It indicates that the PSP-RS group produced smaller and denser speech graphs than the PD and HC groups. In the PSP-RS group, moreover, the average shortest paths of the speech graphs correlated with the severity of motor symptoms. This study shows the potential of the graph theory-based approach in distinguishing the semantic fluency performance of nondemented patients with PSP-RS and PD.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"3771601"},"PeriodicalIF":2.8,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review of MRI Studies and the \"Emotional paiN and social Disconnect (END)\" Brain Model of Suicidal Behavior in Youth.","authors":"Olga Tymofiyeva, Katherine W Reeves, Chace Shaw, Eric Lopez, Sepehr Aziz, Jeffrey E Max, Tony T Yang","doi":"10.1155/2023/7254574","DOIUrl":"10.1155/2023/7254574","url":null,"abstract":"<p><strong>Introduction: </strong>Risk of suicidal ideation and suicidal behaviors greatly increases during adolescence, and rates have risen dramatically over the past two decades. However, few risk factors or biomarkers predictive of suicidal ideation or attempted suicide have been identified in adolescents. Neuroimaging correlates hold potential for early identification of adolescents at increased risk of suicidality and risk stratification for those at high risk of suicide attempt.</p><p><strong>Methods: </strong>In this systematic review, we evaluated neural regions and networks associated with suicidal ideation and suicide attempt in adolescents derived from magnetic resonance imaging (MRI) studies. A total of 28 articles were included in this review.</p><p><strong>Results: </strong>After descriptively synthesizing the literature, we propose the Emotional paiN and social Disconnect (END) model of adolescent suicidality and present two key neural circuits: (1) the emotional/mental pain circuit and (2) the social disconnect/distortion circuit. In the END model, the emotional pain circuit-consisting of the cerebellum, amygdala, and hippocampus-shows similar aberrations in adolescents with suicidal ideation as in those with a history of a suicide attempt (but to a smaller degree). The social disconnect circuit is unique to adolescent suicide attempters and includes the lateral orbitofrontal cortex (OFC), the temporal gyri, and the connections between them.</p><p><strong>Conclusion: </strong>Our proposed END brain model of suicidal behavior in youth, if confirmed by future prospective studies, can have implications for clinical goals of early detection, risk stratification, and intervention development. Treatments that target emotional pain and social disconnect may be ideal interventions for reducing suicidality in adolescents.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"7254574"},"PeriodicalIF":2.8,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41170040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect on Satisfactory Seizure Control and Heart Rate Variability of Thread-Embedding Acupuncture for Drug-Resistant Epilepsy: A Patient-Assessor Blinded, Randomized Controlled Trial.","authors":"Van-Dan Nguyen, Duc-Thang Pham, Minh-An Thuy Le, Guo-Ming Shen","doi":"10.1155/2023/5871991","DOIUrl":"10.1155/2023/5871991","url":null,"abstract":"<p><p>This randomized controlled trial investigates the efficacy of thread-embedding acupuncture (TEA) compared to sham TEA in treating drug-resistant epilepsy (DRE). Fifty-four DRE outpatients were randomly divided into two groups: TEA (27 patients) and sham TEA (27 patients). Both groups received four sessions of TEA or sham TEA, spaced four weeks apart, targeting GV20, GV14, BL15, BL18, ST40, and GB34 acupoints. Antiseizure medications were maintained at consistent doses throughout the study. Outcome measures included satisfactory seizure control, seizure freedom, and heart rate (HR) and heart rate variability (HRV) measurements. TEA demonstrated a significantly higher rate of satisfactory seizure control at follow-up compared to the sham TEA group (37% vs. 3.7%, <i>p</i> = 0.003). While no significant intergroup differences were observed in HR, HRV, and HRV components at each stage, the TEA group experienced a significant decrease in HR and a significant increase in HRV posttreatment. This study demonstrates TEA's effectiveness in managing DRE and suggests its impact may relate to heightened parasympathetic nerve activity. Further research with extended follow-up periods is necessary to validate these findings.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"5871991"},"PeriodicalIF":2.7,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41154796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior Management Training for Parents of Children with Preschool ADHD Based on Parent-Child Interactions: A Multicenter Randomized Controlled, Follow-Up Study.","authors":"Min Feng,&nbsp;Juncai Xu,&nbsp;Mengyao Zhai,&nbsp;Qiaorong Wu,&nbsp;Kangkang Chu,&nbsp;Liping Xie,&nbsp;Rong Luo,&nbsp;Huiping Li,&nbsp;Qiong Xu,&nbsp;Xiu Xu,&nbsp;Xiaoyan Ke","doi":"10.1155/2023/3735634","DOIUrl":"https://doi.org/10.1155/2023/3735634","url":null,"abstract":"<p><strong>Objective: </strong>There is a need to develop optimized, evidence-based parent training programs tailored for preschoolers with attention deficit hyperactivity disorder (ADHD). The objective of this study was to explore a behavioral management training program aimed at the parents of preschool children with ADHD, which directly analyzes parent-child interaction from the perspective of system theory, and the intervention effect on ADHD in preschool children.</p><p><strong>Methods: </strong>A multicenter randomized controlled study was conducted using system-based group therapy with 62 parents of preschool children with ADHD aged four to six years. ADHD symptoms, behavioral and emotional problems, and social functioning were compared with 61 control children whose parents did not receive training by applying the ADHD Rating Scale (ADHD-RS), Strengths and Difficulties Questionnaire (SDQ), and Questionnaire-Children with Difficulties (QCD) at the time of subject entry and at two and six months of entry, respectively.</p><p><strong>Results: </strong>The results of the ADHD-RS assessment showed that children in the intervention group had significantly lower factor scores for attention deficit, hyperactivity, and impulsivity than the children in the control group after parental training and at follow-up (<i>P</i> < 0.05). Total scores on the SDQ scale, as well as character problems, hyperactivity, and peer interaction scores, significantly decreased with statistically significant differences (all <i>P</i> < 0.05), and emotional symptoms and prosocial behavior did not notable decline (<i>P</i> > 0.05). Compared with the control group, the total scores of the QCD scale and the scores of each factor in the intervention group remained significantly higher at the follow-up (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>After continuous intervention for eight weeks, parents were able to help the children with preschool ADHD to improve their ADHD symptoms and emotional behavioral and social functioning significantly, and the efficacy was maintained at the four-month follow-up; the systemic-based parent training in behavior management (PTBM) is applicable to the treatment of preschool ADHD and is worth promoting.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"3735634"},"PeriodicalIF":2.8,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling Suicidality with Multimodal Impulsivity Characterization in Participants with Mental Health Disorder.","authors":"Nidal Moukaddam, Bishal Lamichhane, Ramiro Salas, Wayne Goodman, Ashutosh Sabharwal","doi":"10.1155/2023/8552180","DOIUrl":"10.1155/2023/8552180","url":null,"abstract":"<p><strong>Introduction: </strong>Suicide is one of the leading causes of death across different age groups. The persistence of suicidal ideation and the progression of suicidal ideations to action could be related to impulsivity, the tendency to act on urges with low temporal latency, and little forethought. Quantifying impulsivity could thus help suicidality estimation and risk assessments in ideation-to-action suicidality frameworks.</p><p><strong>Methods: </strong>To model suicidality with impulsivity quantification, we obtained questionnaires, behavioral tests, heart rate variability (HRV), and resting state functional magnetic resonance imaging measurements from 34 participants with mood disorders. The participants were categorized into three suicidality groups based on their Mini-International Neuropsychiatric Interview: none, low, and moderate to severe.</p><p><strong>Results: </strong>Questionnaire and HRV-based impulsivity measures were significantly different between the suicidality groups with higher subscales of impulsivity associated with higher suicidality. A multimodal system to characterize impulsivity objectively resulted in a classification accuracy of 96.77% in the three-class suicidality group prediction task.</p><p><strong>Conclusions: </strong>This study elucidates the relative sensitivity of various impulsivity measures in differentiating participants with suicidality and demonstrates suicidality prediction with high accuracy using a multimodal objective impulsivity characterization in participants with mood disorders.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"8552180"},"PeriodicalIF":2.7,"publicationDate":"2023-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10038199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude and Determinant Factors of Pediatrics Seizures in Pediatrics Emergency Unit at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 2020: A Retrospective and Descriptive Study.","authors":"Asaminew Habtamu,&nbsp;Rahel Argaw,&nbsp;Wagari Tuli,&nbsp;Ayalew Moges","doi":"10.1155/2023/3967899","DOIUrl":"10.1155/2023/3967899","url":null,"abstract":"<p><strong>Background: </strong>One of the most prevalent medical problems affecting kids is epilepsy, which is the most prevalent chronic neurological condition in kids in both developed and developing nations. The spectrum of diseases that make up childhood epilepsy syndromes ranges from mild to potentially fatal. Children may experience seizures due to a variety of illnesses, such as infection, severe brain injury, and anatomical deformity. It is the foremost visit calculates in neurological and cognitive impedance in children in low-income countries as well as the foremost common reason for pediatric clinic confirmations in children from destitute countries. All things considered, constrained things have been conducted in Ethiopia. Hence, this ponder points to survey the size and related variables of pediatric seizures among children conceded to Tikur Anbessa pediatric emergency.</p><p><strong>Methods: </strong>By looking through 256 patient charts, an institution-based retrospective cross-sectional analysis was done. Data collection utilized a systematic checklist that had been evaluated beforehand. The EpiData version 4.4.2.2 was used to enter the data, which was then exported for analysis to the SPSS version 25. Binary logistic regression and descriptive statistics were employed. Variables from the bivariate analysis that had a <i>p</i>-value of less than 0.25 were carried over to multivariate analysis. The strength and existence of the link were assessed using adjusted odds ratios with a 95% confidence interval and a <i>p</i>-value of 0.05, respectively.</p><p><strong>Result: </strong>Patients' ages ranged from 3.7 to 2.8 years on average. 4.5% of patients had seizures, and 155 of them (60.5%) were men, with a male-to-female ratio of (1.5 : 1). Males and females experienced seizures on average at 1.3 (95% CI: 1.1, 1.5) and 2 (95% CI: 1.6, 2.5) years old, respectively. AOR: 2.68 (95% CI: 1.192, 6.68, <i>p</i> = 0.02) and AOR: 2.8 (95% CI: 2.576, 5.302, <i>p</i> = 0.04) both demonstrated statistically significant correlations with pediatric seizure.</p><p><strong>Conclusion: </strong>A vast number of children experienced convulsions, with generalized seizures being the most prevalent form. The chances of a child having a seizure were linked to their family history and where they were born. Therefore, health workers and other people who are involved in healthcare need to work harder on the factors that they have already identified.</p>","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2023 ","pages":"3967899"},"PeriodicalIF":2.8,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}