Cancer Nursing最新文献

{"title":"Comparative Effectiveness of Psychosocial Interventions on Family Function and Resilience for Cancer Caregivers: A Systematic Review With Pairwise and Network Meta-analysis.","authors":"Jiang-Yan Song, Min Liu, Miao Zhang, Zaharah Sulaiman, Tengku Alina Tengku Ismail, Shu-Mei Li, Ye Yun","doi":"10.1097/NCC.0000000000001476","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001476","url":null,"abstract":"<p><strong>Background: </strong>Improving family function and resilience among cancer caregivers is a vital clinical concern requiring thorough research. Psychosocial interventions are expected to enhance family function and strengthen resilience; however, the outcomes can differ significantly, highlighting the necessity for further investigation.</p><p><strong>Objectives: </strong>This study aimed to evaluate the comparative effectiveness of psychosocial interventions in enhancing family function and resilience among caregivers of cancer patients based on data derived from randomized controlled trials.</p><p><strong>Methods: </strong>A systematic review was performed by searching 6 electronic databases and clinical trial registries until July 12, 2024. Pairwise and network meta-analyses (NMA) were performed using the network package in STATA 16.</p><p><strong>Results: </strong>This review identified 12 studies with a total of 1162 participants. The pairwise meta-analysis revealed a significant positive impact of psychosocial interventions on family function: standardized mean difference (SMD), 1.34; 95% confidence interval [CI], 0.16-2.52. NMA showed family interaction approaches (SMD, 0.69; 95% CI, 0.22-1.15) and psychoeducation interventions (SMD, 0.66; 95% CI, 0.24-1.08) both led to improvements in family function. However, neither the pairwise meta-analysis nor the NMA revealed the positive effects of psychosocial interventions on resilience.</p><p><strong>Conclusion: </strong>Evidence suggests that psychosocial interventions can moderately improve family function. Among the various interventions explored, the family interactions demonstrated the most significant potential for effectiveness. However, resilience meta-analyses have not supported our psychosocial intervention recommendations.</p><p><strong>Implications for practice: </strong>This study offers valuable insights for nursing practice, emphasizing the need for nurses to consider the relationships and resources available within the families of cancer patients while providing care.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review of the Effectiveness of Complementary and Alternative Medicine on Nausea and Vomiting in Children With Cancer.","authors":"Ka Yan Ho, Katherine Ka Wai Lam, Wei Xia, Qi Liu, Sau Ying Chiu, Godfrey Chi Fung Chan, William Ho Cheung Li","doi":"10.1097/NCC.0000000000001239","DOIUrl":"10.1097/NCC.0000000000001239","url":null,"abstract":"<p><strong>Background: </strong>Nausea and vomiting are distressing symptoms reported by pediatric oncology patients during cancer treatment. More than 40% of them experience these symptoms even after receiving antiemetics.</p><p><strong>Objective: </strong>Given the limitations of pharmacological interventions, this systematic review synthesized the evidence for the effectiveness of complementary and alternative medicine in controlling nausea and vomiting among pediatric oncology patients.</p><p><strong>Methods: </strong>Ten databases were searched to identify relevant randomized controlled trials. The risk of bias of selected studies was graded using the Cochrane risk-of-bias tool for randomized trials. The primary outcomes were nausea and vomiting. The secondary outcomes were intervention adherence and number of adverse events.</p><p><strong>Results: </strong>Nineteen papers met the inclusion criteria and were included in the review. Sixteen studies showed high risk of bias. The tested interventions were acupuncture, acupressure, aromatherapy, hypnosis, massage, active cognitive distraction/relaxation techniques, creative arts therapy, psychoeducation, and combined massage and acupressure. Acupuncture, hypnosis, and massage interventions improved nausea and vomiting. Fifteen trials reported intervention adherence; only 7 monitored adverse events. The most common reason for dropout was refusal from patients and/or their guardians. A total of 34 adverse events were noted.</p><p><strong>Conclusions: </strong>There is insufficient evidence that complementary and alternative medicine is effective, feasible, or safe in controlling nausea and vomiting among pediatric oncology patients due to high risk of bias.</p><p><strong>Implications for practice: </strong>Acupuncture, hypnosis, and massage appear to have therapeutic benefits. However, more robust studies are needed to address the identified methodological issues and determine the real value of these 3 interventions.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"89-98"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9258399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Nonpharmacologic Interventions for Chemotherapy-Induced Peripheral Neuropathy in Patients With Breast Cancer: A Systematic Review and Network Meta-analysis.","authors":"Ruolin Li, Yu Liu, Rui Xue, Ying Wang, Fuyun Zhao, Lu Chen, Jun-E Liu","doi":"10.1097/NCC.0000000000001278","DOIUrl":"10.1097/NCC.0000000000001278","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect in patients with breast cancer (BC) during treatment. Patients experiencing CIPN develop neuropathic symptoms, which could lead to the modification or discontinuation of chemotherapy. Nonpharmacological interventions can be simple and safe, but evidence of their effectiveness in patients with BC experiencing CIPN is currently insufficient.</p><p><strong>Objective: </strong>To compare and rank the effectiveness of nonpharmacologic interventions for CIPN in patients with BC.</p><p><strong>Methods: </strong>We conducted a systematic search of randomized controlled trials registered from database inception until October 2022 in 7 databases. We assessed studies that met the inclusion and exclusion criteria and evaluated the risk of bias. Network meta-analysis was conducted using Stata SE 17.0 (StataCorp, College Station, Texas).</p><p><strong>Results: </strong>A total of 13 studies involving 9 nonpharmacologic interventions and comprising 571 participants were included. The results of the network meta-analysis showed that cryotherapy (standard mean difference, -1.22; 95% confidence interval, -2.26 to -0.17) exerted significant effects versus usual care. Cryotherapy (surface under the cumulative ranking area [SUCRA]: 0.74) was associated with the highest likelihood of effectively alleviating CIPN in patients with BC, followed by exercise (SUCRA: 0.62) and self-acupressure (SUCRA: 0.59).</p><p><strong>Conclusions: </strong>Cryotherapy was the most effective nonpharmacologic intervention for alleviating CIPN in patients with BC. Large-scale studies are required to verify the present findings.</p><p><strong>Implications for practice: </strong>This study provides evidence regarding the effectiveness of nonpharmacologic interventions for CIPN. Physicians and nurses could incorporate cryotherapy into clinical practice to alleviate CIPN in patients with BC.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"E98-E110"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41240573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening Nursing Implications.","authors":"Sarah H Kagan","doi":"10.1097/NCC.0000000000001453","DOIUrl":"10.1097/NCC.0000000000001453","url":null,"abstract":"","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"154"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing the Symptom Clusters Among Children With Acute Lymphoblastic Leukemia During Chemotherapy Based on Electronic Nursing Records.","authors":"Yuxin Wang, Hongxia Xie, Hao Jiang, Meijia Chen, Liya Ren, Chaoqun Dong","doi":"10.1097/NCC.0000000000001287","DOIUrl":"10.1097/NCC.0000000000001287","url":null,"abstract":"<p><strong>Background: </strong>Children with acute lymphoblastic leukemia often experience various physical and psychological symptoms during chemotherapy. Previous studies have used predetermined symptom inventories to analyze the complex relationships between these symptoms, which has certain limitations.</p><p><strong>Objective: </strong>The aim of this study was to explore the dynamic changes in symptom clusters among children with acute lymphoblastic leukemia during chemotherapy using electronic nursing records.</p><p><strong>Methods: </strong>Electronic nursing records for 2021 (N = 14 490) were obtained from a pediatric hematology department. A natural language processing tool was used to identify the presence of 46 symptoms in 3 chemotherapy phases of induction, consolidation, and maintenance. Incidence of symptom documentation was calculated by notes and patients, and principal component analysis and cluster analysis were performed for symptoms with an incidence above 15%.</p><p><strong>Results: </strong>The most common symptoms included bleeding, cough, and vomiting. The number of symptom clusters in each chemotherapy period was 7, 6, and 4, respectively. There were upper gastrointestinal, respiratory system, lower gastrointestinal, skin-related, psychological, self-image disorder, and other discomfort symptom clusters in the induction period. Notably, the upper gastrointestinal, respiratory system, lower gastrointestinal, and skin-related symptom clusters persisted through the consolidation and maintenance periods. Neurological and other discomfort symptom clusters were observed during the consolidation period.</p><p><strong>Conclusion: </strong>Symptom clusters of children with acute lymphoblastic leukemia at various stages of chemotherapy showed a certain level of stability and dynamics, informing healthcare providers in developing continuous symptom management.</p><p><strong>Implications for practice: </strong>Medical staff should explore targeted intervention programs based on characteristics of symptom clusters at different chemotherapy stages, to improve the efficiency of symptom management and alleviate the symptom burden of children.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"138-146"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41184094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher Levels of Multiple Types of Stress Are Associated With Worse State Anxiety and Morning Fatigue Profiles in Patients Receiving Chemotherapy.","authors":"Philip Garcia, Astrid Block, Sueann Mark, Lynda Mackin, Steven M Paul, Bruce A Cooper, Yvette P Conley, Marilyn J Hammer, Jon D Levine, Christine Miaskowski","doi":"10.1097/NCC.0000000000001304","DOIUrl":"10.1097/NCC.0000000000001304","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and fatigue are common problems in patients receiving chemotherapy. Unrelieved stress is a potential cause for the co-occurrence of these symptoms.</p><p><strong>Objectives: </strong>The aims of this study were to identify subgroups of patients with distinct state anxiety and morning fatigue profiles and evaluate for differences among these subgroups in demographic and clinical characteristics, as well as measures of global, cancer-specific, and cumulative life stress and resilience and coping.</p><p><strong>Methods: </strong>Patients (n = 1335) completed measures of state anxiety and morning fatigue 6 times over 2 cycles of chemotherapy. All of the other measures were completed prior to the second or third cycle of chemotherapy. Latent profile analysis was used to identify the state anxiety and morning fatigue profiles.</p><p><strong>Results: </strong>Three distinct joint profiles were identified: Low Anxiety and Low Morning Fatigue (59%), Moderate Anxiety and Moderate Morning Fatigue (33.4%), and High Anxiety and High Morning Fatigue (7.6%). Patients in the 2 highest classes were younger, were less likely to be married/partnered, and had a higher comorbidity burden. All of the stress scores demonstrated a dose-response effect (ie, as anxiety and morning fatigue profiles worsened, stress increased). Patients in the 2 highest classes reported higher rates of emotional abuse, physical neglect, physical abuse, and sexual harassment.</p><p><strong>Conclusions: </strong>More than 40% of these patients experienced moderate to high levels of both anxiety and morning fatigue. Higher levels of all 3 types of stress were associated with the 2 highest profiles.</p><p><strong>Implications for practice: </strong>Clinicians need to perform comprehensive evaluations of patients' levels of stress and recommend referrals to psychosocial services.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"E75-E89"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11263502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139522026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximizing Professional-Led Sexual Well-being Support in Cancer Care: Findings From a Qualitative Process Evaluation Following Healthcare Professionals' Engagement With an eLearning Resource.","authors":"Claire Victoria Cassells, Cherith Jane Semple, Sheena Ruth Stothers, Sharon Linsey Bingham","doi":"10.1097/NCC.0000000000001313","DOIUrl":"10.1097/NCC.0000000000001313","url":null,"abstract":"<p><strong>Background: </strong>Provision of healthcare professional (HP)-led sexual support in cancer care is lacking, perpetuated by barriers including a lack of HP awareness of sexual concerns and strategies to help patients and partners cope. In response, the Maximizing Sexual Wellbeing|Cancer Care eLearning resource (MSW|CC) was developed and demonstrated efficacy in reducing HPs' attitudinal barriers to the provision of sexual support. However, the mechanisms for such change are not yet known.</p><p><strong>Objective: </strong>A qualitative process evaluation was used to explore mechanisms that influence HP engagement with MSW|CC and its adoption into practice.</p><p><strong>Methods: </strong>Semistructured interviews were conducted with HPs providing cancer care in Northern Ireland upon MSW|CC completion. Interviews were audio-recorded, transcribed verbatim, and thematically analyzed.</p><p><strong>Results: </strong>Seventeen participants were interviewed, and 4 key themes were identified: (1) MSW|CC raises HPs' awareness of the need for holistic sexual support as part of routine clinical care; (2) MSW|CC prepares and equips HPs to provide sexual support in cancer care; (3) MSW|CC is coherent, engaging, and acceptable; and (4) MSW|CC: moving forward.</p><p><strong>Conclusion: </strong>Participants derived benefits from MSW|CC, deeming it an acceptable resource. Insights into MSW|CC mechanisms of success were identified, including language to address sexual concerns, alongside patient referral resources. Perceived MSW|CC shortcomings from an earlier study were confirmed as a software issue.</p><p><strong>Implications for practice: </strong>Healthcare professionals require training and resources to enhance sexual support provision in cancer care. Proactive implementation strategies used to maximize HP engagement with MSW|CC could equip HPs with tools to improve patient sexual outcomes after cancer.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"147-153"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Symptom Burden Predicts Poorer Quality of Life Among Children and Adolescents Receiving Hematopoietic Stem Cell Transplantation or Chimeric Antigen Receptor T-Cell Therapy.","authors":"Kathleen E Montgomery, Jennifer L Raybin, Kimberly Powers, Melody Hellsten, Paula Murray, Jessica Ward","doi":"10.1097/NCC.0000000000001337","DOIUrl":"10.1097/NCC.0000000000001337","url":null,"abstract":"<p><strong>Background: </strong>Children with cancer and other serious illnesses experience symptom burden during hematopoietic stem cell transplantation and chimeric antigen receptor T-cell therapy, yet limited research has characterized how these symptoms interact with overall quality of life over time.</p><p><strong>Objective: </strong>The aim of this study was to examine the longitudinal relationship between symptoms and quality of life in children receiving hematopoietic stem cell transplantation or chimeric antigen receptor T-cell therapy.</p><p><strong>Methods: </strong>A multisite study design was used to collect symptom and quality of life information at pre-cell infusion and days +30, +60, and +90 from children (N = 140) receiving hematopoietic stem cell transplantation and chimeric antigen receptor T-cell therapy. A longitudinal parallel process model was used to characterize the relationship between symptoms and quality of life.</p><p><strong>Results: </strong>Children (mean age, 8.4 years) received allogeneic transplant (57.9%), autologous transplant (25.7%), or chimeric antigen receptor T-cell therapy (16.4%). Symptom prevalence was highest at baseline (>50%) for pain, fatigue, nausea, vomiting, and low appetite. Quality of life scores were worse at baseline (mean [SD], 69.5 [15.8]) and improved by 10 points by day +90. The longitudinal model indicated high symptom prevalence at baseline predicted worse quality of life at both baseline and day +90.</p><p><strong>Conclusions: </strong>Children felt worse early in the treatment trajectory and improved by day +90. The level of symptom burden predicted the overall quality of life at all time points.</p><p><strong>Implications for practice: </strong>Children experiencing high symptom burden should receive frequent assessment and enhanced symptom management throughout the treatment trajectory to mitigate negative impacts on quality of life.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"E111-E120"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Factors for Hyperglycemia in Patients Receiving Chemotherapy.","authors":"Jiyeong Kim, Kyung Hee Lim","doi":"10.1097/NCC.0000000000001271","DOIUrl":"10.1097/NCC.0000000000001271","url":null,"abstract":"<p><strong>Background: </strong>Approximately 10% to 30% of patients who receive chemotherapy experience hyperglycemia, which can affect the adverse reactions and treatment efficacy of chemotherapy. However, there is a paucity of research to explore the factors affecting hyperglycemia and include them in nursing interventions.</p><p><strong>Objective: </strong>The aim of this study was to understand the prognostic factors of hyperglycemia in cancer patients on chemotherapy.</p><p><strong>Methods: </strong>This retrospective, descriptive study included 134 adult patients with cancer receiving chemotherapy at Keimyeng University Dongsan Hospital in Daegu between July 1, 2021, and March 31, 2022. Data were analyzed using frequency, percentage, average, and standard deviation statistics and compared by t test, χ 2 test, and logistic regression analysis.</p><p><strong>Results: </strong>Logistic regression analysis revealed that sex (male) (95% confidence interval [CI], 7.24-745.49; odds ratio [OR], 73.48); education (95% CI, 4.02-201.59; OR, 28.46); exercise durations of 30 to 60 minutes (95% CI, 0.00-0.06; OR, 0.01), 60 to 90 minutes (95% CI, 0.00-0.05, OR = 0.01), and ≥90 minutes (95% CI, 0.00-0.42; OR, 0.03); exercise amount ≥ 2000 kcal/wk (95% CI, 0.01-0.77; OR, 0.06); and daily fat (95% CI, 1.02-1.14; OR, 1.08), protein (95% CI, 0.82-0.95; OR, 0.88), and seaweed (95% CI, 0.85-0.99; OR, 0.92) intake were significant predictors of hyperglycemia.</p><p><strong>Conclusion: </strong>The prognostic factors of hyperglycemia should be included in nursing interventions to prevent and manage hyperglycemia, which in turn may help reduce adverse reactions related to chemotherapy and improve treatment efficacy.</p><p><strong>Implications for practice: </strong>To prevent and manage hyperglycemia in patients on chemotherapy, prognostic factors, including exercise and protein, fat, and seaweed consumption, should be considered in nursing interventions. Particularly, in men and patients with low education levels who are at a high risk of hyperglycemia, nursing interventions for diet and exercise should be individualized.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"112-120"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138292342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness and Safety of Nurse-Led Auricular Acupressure on Chemotherapy-Induced Peripheral Neuropathy Among Patients With Breast Cancer: A Randomized, Double-Blind, Sham-Controlled Trial.","authors":"Mi Sook Jung, Mijung Kim, Eun Hee Sohn, Jin Sun Lee","doi":"10.1097/NCC.0000000000001286","DOIUrl":"10.1097/NCC.0000000000001286","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a major symptom of distress among chemotherapy-treated cancer survivors. Although various interventions have been attempted, there is no criterion-standard treatment.</p><p><strong>Objective: </strong>The aim of this study was to examine the efficacy and safety of auricular acupressure (AA) in improving peripheral neuropathy symptoms in breast cancer patients undergoing taxane-based treatment.</p><p><strong>Methods: </strong>A total of 51 eligible participants were enrolled and randomly allocated (1:1) to AA or sham control groups. The intervention was performed weekly for 3 weeks using different ear points, depending on the group. The Total Neuropathy Score was used to measure CIPN objectively. The Numerical Rating Scale and the European Organization for Research and Treatment of Cancer Quality of Life Chemotherapy-Induced Peripheral Neuropathy-20 were used to measure the subjective symptoms of CIPN. Outcomes were compared between groups by time interaction using generalized estimating equations based on the intention-to-treat principle.</p><p><strong>Results: </strong>Only 1 participant dropped out because of nausea and mild fever. The results of generalized estimating equations showed significant improvement in Numerical Rating Scale scores on the hands and feet and total Chemotherapy-Induced Peripheral Neuropathy-20 in the experimental group compared with the sham control group (all P s < .05). Although the experimental group showed a greater reduction in Total Neuropathy Score scores than the sham control group, no significant differences were found.</p><p><strong>Conclusion: </strong>Auricular acupressure is an effective and safe nurse-led intervention for managing CIPN symptoms in breast cancer patients.</p><p><strong>Implications for practice: </strong>The findings help nurses to integrate AA easily and usefully into nursing care, contributing to managing symptoms of CIPN in cancer patients and survivors.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":"E64-E74"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49684600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}