Cancer Nursing最新文献

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Psychological Resilience in Newly Diagnosed Prostate Cancer Survivors: A Longitudinal Study.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-20 DOI: 10.1097/NCC.0000000000001491
Ching-Hui Chien, Kuan-Lin Liu, Cheng-Keng Chuang, Chun-Te Wu, See-Tong Pang, Kai-Jie Yu, Po-Hung Lin
{"title":"Psychological Resilience in Newly Diagnosed Prostate Cancer Survivors: A Longitudinal Study.","authors":"Ching-Hui Chien, Kuan-Lin Liu, Cheng-Keng Chuang, Chun-Te Wu, See-Tong Pang, Kai-Jie Yu, Po-Hung Lin","doi":"10.1097/NCC.0000000000001491","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001491","url":null,"abstract":"<p><strong>Background: </strong>Psychological resilience is considered a dynamic process or outcome. Most studies that have examined the psychological resilience of prostate cancer survivors have used cross-sectional designs, limiting the understanding of changes in psychological resilience across different stages of the disease.</p><p><strong>Objectives: </strong>To investigate changes in psychological resilience and demoralization among newly diagnosed prostate cancer survivors from before treatment to 1 year after treatment initiation as well as the associated influencing factors.</p><p><strong>Methods: </strong>A longitudinal design was adopted, and cases were collected from the outpatient department. Data collection occurred at four time points: prior to treatment after the treatment decision was made and at 3, 6, and 12 months after treatment. Study variables included demographic characteristics, disease characteristics, physical symptoms, fear of cancer recurrence, social participation, cancer-related self-efficacy, psychological resilience, and demoralization.</p><p><strong>Results: </strong>The psychological resilience and demoralization scores of prostate cancer survivors at 3, 6, and 12 months after treatment were similar to their scores before treatment. Survivors with higher fear of cancer recurrence and lower cancer-related self-efficacy had poorer psychological resilience and more severe demoralization. Severe hormonal symptoms and lower interpersonal relationship activity participation were associated with more severe demoralization in survivors with prostate cancer.</p><p><strong>Conclusions: </strong>Fear of cancer recurrence, self-efficacy, hormonal symptoms, and interpersonal activity participation are associated with psychological resilience and demoralization.</p><p><strong>Implications for practice: </strong>Assessing psychological resilience and demoralization is crucial in prostate cancer care. Integrated self-management interventions that address physical, psychological, and social aspects can enhance survivors' resilience.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Associated With Physical Activity During Hospitalization for Hematopoietic Cell Transplantation and After Discharge: A Pilot Study.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-20 DOI: 10.1097/NCC.0000000000001494
Gisele C Tlusty, Ann M Berger, Vijaya R Bhatt, Eileen D Hacker, John M Noble, Windy W Alonso
{"title":"Factors Associated With Physical Activity During Hospitalization for Hematopoietic Cell Transplantation and After Discharge: A Pilot Study.","authors":"Gisele C Tlusty, Ann M Berger, Vijaya R Bhatt, Eileen D Hacker, John M Noble, Windy W Alonso","doi":"10.1097/NCC.0000000000001494","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001494","url":null,"abstract":"<p><strong>Background: </strong>The importance of physical activity to support health has been widely demonstrated. Hematopoietic cell transplantation (HCT) requires lengthy hospitalizations resulting in substantial decreases in physical activity. Understanding the factors associated with physical activity during hospitalization and immediately following hospital discharge is vital to support the transition from hospital to home.</p><p><strong>Objective: </strong>To examine the associations among personal factors (exercise self-efficacy, physical and mental health, and symptom severity and interference) and physical activity immediately following HCT.</p><p><strong>Methods: </strong>In this prospective observational pilot study, accelerometers measured physical activity during hospitalization on HCT days 0 to 4 (T1) and days 5 to 9 (T2), and in the first 7 days after hospital discharge (T3). Personal factors were assessed at T1, T2, and T3. Physical activity and personal factors were evaluated for change over time (Friedman test) and associations (Spearman correlations).</p><p><strong>Results: </strong>Participants' (n = 26, 57% male; median age, 55 years [40-65.3]) accelerometer data revealed light and moderate to vigorous physical activity, and median steps decreased significantly as symptoms severity and interference increased from T1 to T2. Exercise self-efficacy was moderate to high from T1 to T3 and was correlated with increased steps at T2 (r = 0.57, P = .05) and increased light physical activity (r = 0.55, P = .05) and steps (r = 0.61, P = .01) at T3.</p><p><strong>Conclusions: </strong>This pilot study provides preliminary evidence of the relationships between physical activity and symptoms, symptom severity, and exercise self-efficacy.</p><p><strong>Implications for practice: </strong>Maintaining high levels of physical activity during hospitalization for HCT may not be possible. Nurses can help patients set realistic expectations for physical activity during hospitalization and immediately after hospital discharge.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Systematic Literature Review of Interventions to Manage Hiccups in Patients With Cancer Undergoing Active Treatment.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-18 DOI: 10.1097/NCC.0000000000001448
Rebecca T Sutcliffe, Ijeoma Julie Eche-Ugwu
{"title":"A Systematic Literature Review of Interventions to Manage Hiccups in Patients With Cancer Undergoing Active Treatment.","authors":"Rebecca T Sutcliffe, Ijeoma Julie Eche-Ugwu","doi":"10.1097/NCC.0000000000001448","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001448","url":null,"abstract":"<p><strong>Background: </strong>Patients with cancer often experience persistent or intractable hiccups, which negatively impact their quality of life. Yet, interventions aimed at managing hiccups among patients with cancer receiving active treatment are lacking.</p><p><strong>Objective: </strong>To describe existing evidence on interventions that address hiccup management in patients with cancer receiving active treatment with curative intent.</p><p><strong>Methods: </strong>Our narrative synthesis review was conducted through a systematic search of 3 electronic databases (CINAHL Complete, PubMed, and HOLLIS) augmented by hand search from January 2003 to July 2023 to retrieve peer-reviewed articles published in English. Our review was guided by PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) and registered through the National Institute for Health Research, International Prospective Register of Systematic Reviews (CRD42023444545).</p><p><strong>Results: </strong>The database searches yielded 2686 records. After removing duplicates and ineligible articles, 13 articles met the inclusion criteria. Most were noninterventional observational studies. The most common pharmacologic interventions were as follows: steroid rotation (replacing dexamethasone with methylprednisolone or omitting dexamethasone), baclofen, and olanzapine. Of these pharmacologic interventions, replacing dexamethasone with another antiemetic was most beneficial in reducing hiccups. Baclofen was also found to be beneficial in reducing chronic or intractable hiccups. Acupuncture was found to be an effective nonpharmacologic intervention.</p><p><strong>Conclusions: </strong>This review identified several promising interventions such as steroid rotation (replacing dexamethasone with methylprednisolone or omitting dexamethasone), baclofen, and acupuncture for hiccup management among patients with cancer undergoing active treatment.</p><p><strong>Implications for practice: </strong>Future studies to identify efficacious interventions for hiccups among patients with cancer receiving active treatment are warranted.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family Resilience Factors Associated With Family Adaptation of Children With Acute Leukemia: A Cross-sectional Study.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-10 DOI: 10.1097/NCC.0000000000001484
Luyao Wang, Xiaoliang Tong, Jojo Wong, Yuqiao Xiao, Guiyuan Ma, Can Gu
{"title":"Family Resilience Factors Associated With Family Adaptation of Children With Acute Leukemia: A Cross-sectional Study.","authors":"Luyao Wang, Xiaoliang Tong, Jojo Wong, Yuqiao Xiao, Guiyuan Ma, Can Gu","doi":"10.1097/NCC.0000000000001484","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001484","url":null,"abstract":"<p><strong>Background: </strong>Childhood leukemia critically disrupts family life, needing support for adaptation and resilience.</p><p><strong>Objective: </strong>Having investigated the main factors influencing the adaptation of families with children with leukemia, we provide support for clinical nurses to develop effective interventions to promote the adaptation of families with children with leukemia in future clinical practice.</p><p><strong>Method: </strong>This cross-sectional study surveyed 197 parents of children (≤14 years old) with acute leukemia from 4 hospitals in Changsha, China. Four questionnaires assessed family resilience: the Family Hardiness Index, Perceived Social Support Scale, Family Management Measure, and Family Crisis-Oriented Personal Evaluation Scale. Family adaptation was measured using the Family Adaptability and Cohesion Evaluation Scale.</p><p><strong>Results: </strong>The average family adaptation score for families of children with acute leukemia was 48.58 ± 8.71. Key resilience factors included family hardiness (β = .493, P < .001), social support (β = .096, P < .05), parental marital status (β = -6.964, P < .05), parental education level (β = 1.53, P < .05), and family coping strategies (β = .127, P < .05). Together, these factors explained 33.6% of the variance in family adaptation (F = 19.724, P < .001).</p><p><strong>Conclusion: </strong>Nurses should deliver family-centered care, bolster family resilience, and enhance coping skills, particularly for families with less education or single/divorced parents, to help them navigate the challenges of childhood leukemia.</p><p><strong>Implications for practice: </strong>The findings hope to guide global nursing support for leukemia patient families.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"The Cancer Is Back": Reflecting on Recurrence, Relapse, and Remission in Adolescent Cancer Research.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-10 DOI: 10.1097/NCC.0000000000001483
Daniela Bonfietti Rodrigues, Fernanda Machado Silva-Rodrigues
{"title":"\"The Cancer Is Back\": Reflecting on Recurrence, Relapse, and Remission in Adolescent Cancer Research.","authors":"Daniela Bonfietti Rodrigues, Fernanda Machado Silva-Rodrigues","doi":"10.1097/NCC.0000000000001483","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001483","url":null,"abstract":"","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Remote Counseling on Screening Uptake in the First-Degree Relatives of Colorectal Cancer Patients: A Systematic Review and Meta-analysis.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-10 DOI: 10.1097/NCC.0000000000001467
Bei Dong, Yongfeng Chen, Dongting Zhang, Kai Chow Choi, Carmen W H Chan
{"title":"Effect of Remote Counseling on Screening Uptake in the First-Degree Relatives of Colorectal Cancer Patients: A Systematic Review and Meta-analysis.","authors":"Bei Dong, Yongfeng Chen, Dongting Zhang, Kai Chow Choi, Carmen W H Chan","doi":"10.1097/NCC.0000000000001467","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001467","url":null,"abstract":"<p><strong>Background: </strong>Remote counseling has been used to facilitate the uptake of colorectal cancer screening in the first-degree relatives of colorectal cancer patients, but a comprehensive evaluation of such an intervention remains lacking.</p><p><strong>Objective: </strong>The aim of this study was to explore the characteristics of remote counseling and its effect on the first-degree relatives of colorectal cancer patients.</p><p><strong>Methods: </strong>Eight English databases and 3 Chinese databases were searched from their inception to June 2024. Gray literature and the reference lists of the included studies were also examined. Randomized controlled trials conforming to the inclusion and exclusion criteria were screened and extracted. All meta-analyses were performed with Review Manager 5.3.</p><p><strong>Results: </strong>Five studies with 2601 first-degree relatives of colorectal cancer patients were included in this systematic review. Meta-analysis showed that remote counseling could significantly increase the colorectal cancer screening rate (relative risk, 1.65; 95% confidence interval, 1.46-1.86; P < .01). Among interventions of this kind, mailing tailored printing materials demonstrated a beneficial effect (relative risk, 1.57; 95% confidence interval, 1.22-2.03; P < .01). However, evidence that remote counseling could improve knowledge of and health beliefs about colorectal cancer and screening was limited.</p><p><strong>Conclusion: </strong>Remote counseling had a positive effect on colorectal cancer screening uptake in the first-degree relatives of colorectal cancer patients.</p><p><strong>Implications for practice: </strong>The first-degree relatives of colorectal cancer patients have an increased risk of developing the disease. Remote counseling is an effective intervention for improving their screening rate. However, more rigorous theory-driven randomized controlled trials are needed to determine an optimal intervention program.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the Role of Social Determinants of Health on Adherence to Pap Screening Guidelines for US Women Aged 21 to 64 Years: Evidence From the 2022 Health Information National Trends Survey.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-07 DOI: 10.1097/NCC.0000000000001481
Adaeze C Aroh, Ifeanyi Madujibeya, Henry Asante Antwi, Ugonwa Aroh, Megan Pine, Adebola Adegboyega
{"title":"Examining the Role of Social Determinants of Health on Adherence to Pap Screening Guidelines for US Women Aged 21 to 64 Years: Evidence From the 2022 Health Information National Trends Survey.","authors":"Adaeze C Aroh, Ifeanyi Madujibeya, Henry Asante Antwi, Ugonwa Aroh, Megan Pine, Adebola Adegboyega","doi":"10.1097/NCC.0000000000001481","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001481","url":null,"abstract":"<p><strong>Background: </strong>Social determinants of health (SDOH) domains outlined by the American Cancer Society may provide a comprehensive understanding of the factors that influence adherence to cervical cancer screening recommendations. However, the relationship between the domains and screening adherence has not been previously examined.</p><p><strong>Objective: </strong>This study aims to explore the relationship between SDOH domains and adherence to cervical cancer screening guidelines among US women aged 21 to 64 years, using data from the Health Information National Trends Survey cycle 6 (n = 6252).</p><p><strong>Methods: </strong>Weighted multivariate logistic regressions, incorporating jackknife replicate weights, were conducted using all the domains of SDOH.</p><p><strong>Results: </strong>The sample includes 2037 respondents. An estimated 74.3% (61 318 532/82 499 191; 95% confidence interval [CI], 70.9%-78.0%) of the weighted adult population of women aged 21 to 64 years in the United States were adherent with the US Preventive Task Force screening recommendations. The mean age of the adherent and nonadherent populations was 43.6 years (95% CI, 42.9-44.34 years) and 42.5 years (95% CI, 40.5-44.5 years), respectively. Adherence to cervical cancer screening guidelines was significantly associated with decreasing social isolation independent of ethnicity, body mass index, knowledge of cervical cancer, marital status, and urban-rural designation (odds ratio, 0.98; P = .009).</p><p><strong>Conclusions: </strong>The screening rate is below the Healthy People 2030 target (79.2%). These findings underscore the importance of comprehensive approaches to address social isolation and its influence on screening behaviors.</p><p><strong>Implications for practice: </strong>Researchers and health practitioners should increase attention to and embrace the 6 foundational pillars of the Surgeon General's advisory framework to advance social connection in the United States.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of Life and Cancer-Related Experiences of Late-Stage and Metastatic Colorectal Cancer Survivors: A Mixed-Methods Study.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-06 DOI: 10.1097/NCC.0000000000001480
Krista A Brown, Katrina M Poppert Corts, Sharon Medcalf, Melissa Acquazzino, Robin M Lally
{"title":"Quality of Life and Cancer-Related Experiences of Late-Stage and Metastatic Colorectal Cancer Survivors: A Mixed-Methods Study.","authors":"Krista A Brown, Katrina M Poppert Corts, Sharon Medcalf, Melissa Acquazzino, Robin M Lally","doi":"10.1097/NCC.0000000000001480","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001480","url":null,"abstract":"<p><strong>Background: </strong>People with late-stage and metastatic colorectal cancer (CRC) are living longer, with rates increasing over time, necessitating a greater understanding of their survivorship experiences.</p><p><strong>Objective: </strong>The purpose of this study was to explore the quality of life (QoL) and cancer-related experiences of stages III and IV CRC survivors and to inform oncology nursing practice and survivorship care.</p><p><strong>Interventions/methods: </strong>This sequential, explanatory mixed-method study used a cross-sectional Functional Assessment of Cancer Therapy-Colorectal survey and semistructured interviews to explore QoL and cancer-related experiences of stages III and IV CRC survivors. The study was guided by the Ferrell QoL model. Descriptive statistics and directed and summative content analysis were utilized, followed by integration using joint displays.</p><p><strong>Results: </strong>Thirty-one CRC survivors participated in the study; 24 completed the Functional Assessment of Cancer Therapy-Colorectal, and 12 participated in the semistructured interviews. Results identified 8 QoL themes: control, acceptance, normalcy, resilience, trust, isolation, and anger/frustration with support needs, including ostomy appliance management and shared experiences from other CRC survivors.</p><p><strong>Conclusions: </strong>Stage III/IV CRC survivors experience substantial physical, psychological, social, and spiritual cancer-related challenges. Integration of quantitative and qualitative data in this study highlighted QoL domains for future clinical intervention.</p><p><strong>Implications for practice: </strong>These data inform oncology nurses and other healthcare providers regarding QoL domains that may warrant greater assessment among late-stage and metastatic CRC survivors experiencing low, moderate, or high QoL. Interventions to facilitate social and community support for late-stage and metastatic CRC survivors through support groups, one-on-one interactions, or virtual online platforms are warranted.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptom Clusters and Social Support in Patients With Lung Cancer Undergoing Anti-Programmed Death 1/Programmed Death Ligand 1 Immunotherapy: A Cross-sectional Analysis.
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-06 DOI: 10.1097/NCC.0000000000001482
Jinling Guo, Yanzhu Qin, Caixia Li, Juhua He, Lijun Zeng, Jing Peng
{"title":"Symptom Clusters and Social Support in Patients With Lung Cancer Undergoing Anti-Programmed Death 1/Programmed Death Ligand 1 Immunotherapy: A Cross-sectional Analysis.","authors":"Jinling Guo, Yanzhu Qin, Caixia Li, Juhua He, Lijun Zeng, Jing Peng","doi":"10.1097/NCC.0000000000001482","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001482","url":null,"abstract":"<p><strong>Background: </strong>Anti-programmed death 1/programmed death ligand 1 immunotherapy has greatly advanced lung cancer treatment; however, the symptom clusters experienced by patients during immunotherapy, their influencing factors, and the correlation with social support warrant further attention.</p><p><strong>Objectives: </strong>The aims of this study were to explore symptom clusters in patients with lung cancer undergoing anti-programmed death 1/programmed death ligand 1 immunotherapy and investigate their relationship with social support.</p><p><strong>Methods: </strong>We studied 133 patients with lung cancer admitted to a Chinese oncology unit. A cross-sectional survey assessed symptoms using the MD Anderson Symptom Inventory and social support using the Social Support Rating Scale. Sociodemographic and disease data were also collected. Exploratory factor analysis was used to identify symptom clusters, and binary logistic regression analysis was used to analyze the influencing factors.</p><p><strong>Results: </strong>Patients experienced various symptoms, with fatigue and cough being the most common and severe. Exploratory factor analysis revealed 3 clusters: general, lung cancer-specific, and gastrointestinal symptoms. Logistic regression showed that male sex was associated with general and lung cancer-specific symptom clusters. In contrast, previous radiotherapy was associated with the gastrointestinal cluster (P < .05). Social support was negatively correlated with the severity of some symptom clusters.</p><p><strong>Conclusion: </strong>The 3 symptom clusters adversely affected patients undergoing immunotherapy. Low social support exacerbated symptom severity.</p><p><strong>Implications for practice: </strong>Male patients should be monitored for general and lung cancer-specific symptoms, and those with a history of radiotherapy should be monitored for gastrointestinal symptoms. We recommend enhancing social support to alleviate symptom severity and tailoring symptom management strategies for individualized patient care.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Effectiveness of Psychosocial Interventions on Family Function and Resilience for Cancer Caregivers: A Systematic Review With Pairwise and Network Meta-analysis. 社会心理干预对癌症护理者家庭功能和复原力的比较效果:通过配对和网络元分析的系统性综述》。
IF 2.4 3区 医学
Cancer Nursing Pub Date : 2025-03-04 DOI: 10.1097/NCC.0000000000001476
Jiang-Yan Song, Min Liu, Miao Zhang, Zaharah Sulaiman, Tengku Alina Tengku Ismail, Shu-Mei Li, Ye Yun
{"title":"Comparative Effectiveness of Psychosocial Interventions on Family Function and Resilience for Cancer Caregivers: A Systematic Review With Pairwise and Network Meta-analysis.","authors":"Jiang-Yan Song, Min Liu, Miao Zhang, Zaharah Sulaiman, Tengku Alina Tengku Ismail, Shu-Mei Li, Ye Yun","doi":"10.1097/NCC.0000000000001476","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001476","url":null,"abstract":"<p><strong>Background: </strong>Improving family function and resilience among cancer caregivers is a vital clinical concern requiring thorough research. Psychosocial interventions are expected to enhance family function and strengthen resilience; however, the outcomes can differ significantly, highlighting the necessity for further investigation.</p><p><strong>Objectives: </strong>This study aimed to evaluate the comparative effectiveness of psychosocial interventions in enhancing family function and resilience among caregivers of cancer patients based on data derived from randomized controlled trials.</p><p><strong>Methods: </strong>A systematic review was performed by searching 6 electronic databases and clinical trial registries until July 12, 2024. Pairwise and network meta-analyses (NMA) were performed using the network package in STATA 16.</p><p><strong>Results: </strong>This review identified 12 studies with a total of 1162 participants. The pairwise meta-analysis revealed a significant positive impact of psychosocial interventions on family function: standardized mean difference (SMD), 1.34; 95% confidence interval [CI], 0.16-2.52. NMA showed family interaction approaches (SMD, 0.69; 95% CI, 0.22-1.15) and psychoeducation interventions (SMD, 0.66; 95% CI, 0.24-1.08) both led to improvements in family function. However, neither the pairwise meta-analysis nor the NMA revealed the positive effects of psychosocial interventions on resilience.</p><p><strong>Conclusion: </strong>Evidence suggests that psychosocial interventions can moderately improve family function. Among the various interventions explored, the family interactions demonstrated the most significant potential for effectiveness. However, resilience meta-analyses have not supported our psychosocial intervention recommendations.</p><p><strong>Implications for practice: </strong>This study offers valuable insights for nursing practice, emphasizing the need for nurses to consider the relationships and resources available within the families of cancer patients while providing care.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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