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Wider Dissemination of Simplified Chest Compression-Only Cardiopulmonary Resuscitation Training Combined With Conventional Cardiopulmonary Resuscitation Training and 10-Year Trends in Cardiopulmonary Resuscitation Performed by Bystanders in a City. 某城市单纯胸外按压心肺复苏训练与常规心肺复苏训练联合推广及旁观者心肺复苏10年趋势分析
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-07-25 Epub Date: 2023-11-18 DOI: 10.1253/circj.CJ-23-0177
Shunsuke Kawai, Daisuke Kobayashi, Chika Nishiyama, Tomonari Shimamoto, Kosuke Kiyohara, Tetsuhisa Kitamura, Katsuya Tanaka, Kouichi Kinashi, Naho Koyama, Tetsuya Sakamoto, Seishiro Marukawa, Taku Iwami
{"title":"Wider Dissemination of Simplified Chest Compression-Only Cardiopulmonary Resuscitation Training Combined With Conventional Cardiopulmonary Resuscitation Training and 10-Year Trends in Cardiopulmonary Resuscitation Performed by Bystanders in a City.","authors":"Shunsuke Kawai, Daisuke Kobayashi, Chika Nishiyama, Tomonari Shimamoto, Kosuke Kiyohara, Tetsuhisa Kitamura, Katsuya Tanaka, Kouichi Kinashi, Naho Koyama, Tetsuya Sakamoto, Seishiro Marukawa, Taku Iwami","doi":"10.1253/circj.CJ-23-0177","DOIUrl":"10.1253/circj.CJ-23-0177","url":null,"abstract":"<p><strong>Background: </strong>Little is known about how to effectively increase bystander cardiopulmonary resuscitation (CPR), so we evaluated the 10-year trend of the proportion of bystander CPR in an area with wide dissemination of chest compression-only CPR (CCCPR) training combined with conventional CPR training.</p><p><strong>Methods and results: </strong>We conducted a descriptive study after a community intervention, using a prospective cohort from September 2010 to December 2019. The intervention consisted of disseminating CCCPR training combined with conventional CPR training in Toyonaka City since 2010. We analyzed all non-traumatic out-of-hospital cardiac arrest (OHCA) patients resuscitated by emergency medical service personnel. The primary outcome was the trend of the proportion of bystander CPR. We conducted multivariate logistic regression models and assessed the adjusted odds ratio (AOR) using a 95% confidence interval (CI) to determine bystander CPR trends. Since 2010, we have trained 168,053 inhabitants (41.9% of the total population of Toyonaka City). A total of 1,508 OHCA patients were included in the analysis. The proportion of bystander CPR did not change from 2010 (43.3%) to 2019 (40.0%; 1-year incremental AOR 1.02 [95% CI: 0.98-1.05]).</p><p><strong>Conclusions: </strong>The proportion of bystander CPR did not increase even after wider dissemination of CPR training. In addition to continuing wider dissemination of CPR training, other strategies such as the use of technology are necessary to increase bystander CPR.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Differences in Cardiovascular Disease-Related Hospitalization and Mortality in Japan - Analysis of Health Records From a Nationwide Claim-Based Database, the Japanese Registry of All Cardiac and Vascular Disease (JROAD). 日本心血管疾病相关住院率和死亡率的性别差异--基于全国索赔数据库的健康记录分析--日本所有心脏和血管疾病登记处 (JROAD)。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-07-25 Epub Date: 2024-06-06 DOI: 10.1253/circj.CJ-23-0960
Satsuki Noma, Katsuhito Kato, Toshiaki Otsuka, Yoko M Nakao, Rie Aoyama, Atsuko Nakayama, Atsushi Mizuno, Sachiko Kanki, Yuko Wada, Yoshiko Watanabe, Chizuko Aoki-Kamiya, Katsuyuki Hoshina, Saeko Takahashi, Yasuko Bando, Tomomi Ide, Junko Honye, Mariko Harada-Shiba, Aya Saito, Yukiko Nakano, Yasushi Sakata, Kyoko Soejima, Koji Maemura, Yayoi Tetsuou Tsukada
{"title":"Sex Differences in Cardiovascular Disease-Related Hospitalization and Mortality in Japan - Analysis of Health Records From a Nationwide Claim-Based Database, the Japanese Registry of All Cardiac and Vascular Disease (JROAD).","authors":"Satsuki Noma, Katsuhito Kato, Toshiaki Otsuka, Yoko M Nakao, Rie Aoyama, Atsuko Nakayama, Atsushi Mizuno, Sachiko Kanki, Yuko Wada, Yoshiko Watanabe, Chizuko Aoki-Kamiya, Katsuyuki Hoshina, Saeko Takahashi, Yasuko Bando, Tomomi Ide, Junko Honye, Mariko Harada-Shiba, Aya Saito, Yukiko Nakano, Yasushi Sakata, Kyoko Soejima, Koji Maemura, Yayoi Tetsuou Tsukada","doi":"10.1253/circj.CJ-23-0960","DOIUrl":"10.1253/circj.CJ-23-0960","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of cardiovascular disease (CVD) is rising in Japan with its aging population, but there is a lack of epidemiological data on sex differences in CVD, including acute coronary syndrome (ACS), acute heart failure (AHF), and acute aortic disease.</p><p><strong>Methods and results: </strong>This retrospective study analyzed data from 1,349,017 patients (January 2012-December 2020) using the Japanese Registry Of All Cardiac and Vascular Diseases database. ACS patients were youngest on average (70.5±12.9 years) and had the lowest female proportion (28.9%). AHF patients had the oldest mean age (79.7±12.0 years) and the highest proportion of females (48.0%). Acute aortic disease had the highest in-hospital mortality (26.1%), followed by AHF (11.5%) and ACS (8.9%). Sex-based mortality differences were notable in acute aortic disease, with higher male mortality in Stanford Type A acute aortic dissection (AAD) with surgery (males: 14.2% vs. females: 10.4%, P<0.001) and similar rates in Type B AAD (males: 6.2% vs. females: 7.9%, P=0.52). Aging was a universal risk factor for in-hospital mortality. Female sex was a risk factor for ACS and acute aortic disease but not for AHF or Types A and B AAD.</p><p><strong>Conclusions: </strong>Sex-based disparities in the CVD-related hospitalization and mortality within the Japanese national population have been highlighted for the first time, indicating the importance of sex-specific strategies in the management and understanding of these conditions.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Initial Holter Electrocardiogram Index to Predict the Burden of Subsequent Persistent Premature Ventricular Complex in Childhood. 预测儿童期持续性室性早搏负担的初始 Holter 心电图指数
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-07-20 DOI: 10.1253/circj.CJ-24-0438
Gaku Izumi, Satoru Shida, Norio Kobayashi, Hirokuni Yamazawa, Atsuhito Takeda
{"title":"Initial Holter Electrocardiogram Index to Predict the Burden of Subsequent Persistent Premature Ventricular Complex in Childhood.","authors":"Gaku Izumi, Satoru Shida, Norio Kobayashi, Hirokuni Yamazawa, Atsuhito Takeda","doi":"10.1253/circj.CJ-24-0438","DOIUrl":"https://doi.org/10.1253/circj.CJ-24-0438","url":null,"abstract":"<p><strong>Background: </strong>Asymptomatic premature ventricular complex (PVC) in childhood often disappears over time. However, predictive factors for persistent PVC are unknown. We examined predictive factors for persistent PVCs on initial Holter electrocardiogram (ECG) in pediatric patients with asymptomatic PVC.Methods and Results: The initial Holter ECG findings of untreated PVC patients (n=216) between 2010 and 2021 were examined. Multivariable analysis was performed to clarify predictive factors for subsequent persistent PVC burden for each index (age, sex, PVC burden, PVC origin, minimum and maximum mean RR intervals [RRmin and RRmax, respectively]) of the 3 heartbeats of baseline sinus rhythm immediately before the PVC. The median age at initial Holter ECG was 11.6 years (range 5.8-18.8 years), the PVC burden was 5.22% (range 0.01-44.21%), RRmin was 660 ms, RRmax was 936 ms, RRrange (=RRmax-RRmin) was 273 ms, and 15 (7%) PVC runs were identified. The median follow-up period was 5.1 years (range 0.8-9.4 years), and the final Holter PVC burden was 3.99% (range 0-36.38%). In multivariate analysis, RRrange was the only independent risk factor for predicting a final Holter PVC burden >10%, with an area under the curve of 0.920 using an RRrange of 600 ms as the cut-off value.</p><p><strong>Conclusions: </strong>A wide RRrange at the initial Holter ECG may be a predictive indicator for persistent PVC in childhood.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Effectiveness of Acceleration Training as Cardiac Rehabilitation Immediately After Open Heart Surgery ― A Pilot Study ― 开放式心脏手术后立即进行加速训练作为心脏康复的安全性和有效性--一项试点研究
IF 3.3 3区 医学
Circulation Journal Pub Date : 2024-07-13 DOI: 10.1253/circj.cj-24-0352
Yuta Kanazawa, Shunsuke Saito, Shohei Okubo, Taiki Matsuoka, Shotaro Hirota, Shohei Yokoyama, Masahiro Tezuka, Yusuke Takei, Go Tsuchiya, Taisuke Konishi, Koji Ogata, Ikuko Shibasaki, Toshiaki Nakajima, Hirotsugu Fukuda
{"title":"Safety and Effectiveness of Acceleration Training as Cardiac Rehabilitation Immediately After Open Heart Surgery ― A Pilot Study ―","authors":"Yuta Kanazawa, Shunsuke Saito, Shohei Okubo, Taiki Matsuoka, Shotaro Hirota, Shohei Yokoyama, Masahiro Tezuka, Yusuke Takei, Go Tsuchiya, Taisuke Konishi, Koji Ogata, Ikuko Shibasaki, Toshiaki Nakajima, Hirotsugu Fukuda","doi":"10.1253/circj.cj-24-0352","DOIUrl":"https://doi.org/10.1253/circj.cj-24-0352","url":null,"abstract":"</p><p><b><i>Background:</i></b> We examined the safety and efficacy of acceleration training (AT) in patients immediately after cardiac surgery.</p><p><b><i>Methods and Results:</i></b> This randomized controlled study included patients who underwent open-heart surgery using cardiopulmonary bypass. Of these patients, 31 received regular cardiac rehabilitation (CR) and 39 received AT in addition to regular CR (AT group). AT was provided using a vibration platform (Power Plate<sup>®</sup>Pro7<sup>TM</sup>and Power plate<sup>®</sup>personal; Performance Health System, Chicago, IL, USA). The AT group performed 5 static resistance training sessions: squats, wide stance squats, toe stands, banded squats, and front lunges. Each vibration session lasted 30 s. We evaluated the short physical performance battery, anterior mid-thigh thickness, maximum voluntary isometric contraction of the knee extensors, and serum intercellular adhesion molecule (ICAM-1) and vascular cell adhesion molecule (VCAM-1) concentrations as indicators of endothelial function. The observation period was during hospitalization and lasted approximately 20 days. No adverse events occurred during AT. Ultrasound revealed a significantly lower reduction in muscle mass at discharge in the AT group. No significant differences were observed in ICAM-1 and VCAM-1 concentrations between the 2 groups preoperatively, postoperatively, or at discharge.</p><p><b><i>Conclusions:</i></b> AT is considered safe and effective for patients immediately after open-heart surgery. AT, along with regular CR, may prevent skeletal muscle mass loss, muscle weakness, and physical function loss immediately after open-heart surgery.</p>\u0000<p></p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141611133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of 12-Month Angioscopic Thrombi and Yellow Plaque After Drug-Eluting Stent Implantation. 植入药物洗脱支架后 12 个月血管镜血栓和黄色斑块的影响
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-07-11 DOI: 10.1253/circj.CJ-24-0255
Masami Nishino, Yasuyuki Egami, Hiroaki Nohara, Shodai Kawanami, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano, Tatsuya Shiraki, Daisuke Nakamura, Isamu Mizote, Takayuki Ishihara, Toshiaki Mano, Takafumi Ueno, Daisaku Nakatani, Shungo Hikoso, Shinsuke Nanto, Yasushi Sakata
{"title":"Impact of 12-Month Angioscopic Thrombi and Yellow Plaque After Drug-Eluting Stent Implantation.","authors":"Masami Nishino, Yasuyuki Egami, Hiroaki Nohara, Shodai Kawanami, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano, Tatsuya Shiraki, Daisuke Nakamura, Isamu Mizote, Takayuki Ishihara, Toshiaki Mano, Takafumi Ueno, Daisaku Nakatani, Shungo Hikoso, Shinsuke Nanto, Yasushi Sakata","doi":"10.1253/circj.CJ-24-0255","DOIUrl":"https://doi.org/10.1253/circj.CJ-24-0255","url":null,"abstract":"<p><strong>Background: </strong>Coronary angioscopy (CAS) has 2 unique abilities: direct visualization of thrombi and plaque color. However, in the recent drug-eluting stent (DES) era, serial CAS findings after DES implantation have not been fully elucidated. We investigated the impact of CAS findings after implantation of a polymer-free biolimus A9-coated stent (PF-BCS) or durable polymer everolimus-eluting stent (DP-EES).Methods and Results: We investigated serial CAS and optical coherence tomography (OCT) findings at 1 and 12 months in 99 patients who underwent PF-BCS or DP-EES implantation. We evaluated factors correlated with angioscopic thrombi and yellow plaque, and the clinical impact of both thrombi and yellow plaque at 12 months (BTY). The BTY group included 17 (22%) patients. The incidence and grade of thrombi and yellow plaque decreased from 1 to 12 months. Although no patients had newly appearing thrombi at 12 months, 2 DP-EES patients had newly appearing yellow plaque at 12 months. Multivariable analysis revealed HbA1c, minimum stent area, and adequate strut coverage were significant factors correlated with 12-month angioscopic thrombi, and DP-EESs were significantly correlated with 12-month yellow plaque. However, BTY was not correlated with clinical events.</p><p><strong>Conclusions: </strong>The management of diabetes, stent area, and adequate stent coverage are important for intrastent thrombogenicity and polymer-free stents are useful for stabilizing plaque vulnerability.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Dose Prasugrel vs. Standard-Dose Clopidogrel for Patients Undergoing Percutaneous Coronary Intervention 接受经皮冠状动脉介入治疗的患者使用低剂量普拉格雷与标准剂量氯吡格雷的比较
IF 3.3 3区 医学
Circulation Journal Pub Date : 2024-07-09 DOI: 10.1253/circj.cj-24-0173
Toshiki Kuno, Yoshihisa Miyamoto, Keitaro Akita, Satoshi Shoji, Yohei Numasawa, Ikuko Ueda, Shigetaka Noma, Keiichi Fukuda, Shun Kohsaka
{"title":"Low-Dose Prasugrel vs. Standard-Dose Clopidogrel for Patients Undergoing Percutaneous Coronary Intervention","authors":"Toshiki Kuno, Yoshihisa Miyamoto, Keitaro Akita, Satoshi Shoji, Yohei Numasawa, Ikuko Ueda, Shigetaka Noma, Keiichi Fukuda, Shun Kohsaka","doi":"10.1253/circj.cj-24-0173","DOIUrl":"https://doi.org/10.1253/circj.cj-24-0173","url":null,"abstract":"</p><p><b><i>Background:</i></b> Low-dose prasugrel (3.75 mg) is used as maintenance therapy for percutaneous coronary intervention; however, data on long-term outcomes are scarce.</p><p><b><i>Methods and Results:</i></b> We analyzed 5,392 participants in the KiCS-PCI registry who were administered low-dose prasugrel or clopidogrel at discharge between 2008 and 2018 and for whom 2-year follow-up data were available. We adjusted for confounders using matching weight analyses and multiple imputations. Similarly, we used inverse probability- and propensity score-weighted analyses. We also performed instrumental variable analyses. The primary outcomes were acute coronary syndrome (ACS) and bleeding requiring readmission. Secondary outcomes were all-cause death and a composite outcome of ACS, bleeding, heart failure, stroke, coronary bypass requiring admission, and all-cause death. In this cohort, 12.2% of patients were discharged with low-dose prasugrel. Compared with clopidogrel, low-dose prasugrel was associated with a reduced risk of ACS (hazard ratio [HR] 0.58; 95% confidence interval [CI] 0.39–0.85), bleeding (HR 0.62; 95% CI 0.40–0.97), and the composite outcome (HR 0.71; 95% CI 0.59–0.86). Inverse probability-weighted analysis yielded similar results; however, matching weight analysis without multiple imputations and propensity score-matched analyses showed similar outcomes in both groups. Instrumental variable analyses showed reduced risks of ACS and composite outcome for those on low-dose prasugrel. All-cause mortality did not differ in all analyses.</p><p><b><i>Conclusions:</i></b> Low-dose prasugrel demonstrates comparable outcomes to clopidogrel in terms of ACS and bleeding.</p>\u0000<p></p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141573555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment Strategy for Severe Aortic Stenosis With Moderate/Severe Mitral Regurgitation. 重度主动脉瓣狭窄伴中度/重度二尖瓣反流的治疗策略。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-07-05 DOI: 10.1253/circj.CJ-24-0413
Kazuo Shimamura, Shigeru Miyagawa
{"title":"Treatment Strategy for Severe Aortic Stenosis With Moderate/Severe Mitral Regurgitation.","authors":"Kazuo Shimamura, Shigeru Miyagawa","doi":"10.1253/circj.CJ-24-0413","DOIUrl":"https://doi.org/10.1253/circj.CJ-24-0413","url":null,"abstract":"","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of Optical Coherence Tomography-Defined Calcified Nodules in Patients With Acute Coronary Syndrome - A Substudy From the TACTICS Registry. 急性冠状动脉综合征患者中光学相干断层扫描确定的钙化结节的预测因素--来自 TACTICS 登记处的一项子研究。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-26 DOI: 10.1253/circj.CJ-24-0111
Tomoyo Sugiyama, Tsunekazu Kakuta, Masahiro Hoshino, Masahiro Hada, Taishi Yonetsu, Eisuke Usui, Yoshihiro Hanyu, Tatsuhiro Nagamine, Kai Nogami, Hiroki Ueno, Kazuki Matsuda, Kodai Sayama, Tatsuya Sakamoto, Nobuaki Kobayashi, Masamichi Takano, Seita Kondo, Kohei Wakabayashi, Satoru Suwa, Tomotaka Dohi, Hiroyoshi Mori, Shigeki Kimura, Satoru Mitomo, Sunao Nakamura, Takumi Higuma, Junichi Yamaguchi, Makoto Natsumeda, Yuji Ikari, Jun Yamashita, Takehiko Sambe, Sakiko Yasuhara, Takuya Mizukami, Myong Hwa Yamamoto, Tetsuo Sasano, Toshiro Shinke
{"title":"Predictors of Optical Coherence Tomography-Defined Calcified Nodules in Patients With Acute Coronary Syndrome - A Substudy From the TACTICS Registry.","authors":"Tomoyo Sugiyama, Tsunekazu Kakuta, Masahiro Hoshino, Masahiro Hada, Taishi Yonetsu, Eisuke Usui, Yoshihiro Hanyu, Tatsuhiro Nagamine, Kai Nogami, Hiroki Ueno, Kazuki Matsuda, Kodai Sayama, Tatsuya Sakamoto, Nobuaki Kobayashi, Masamichi Takano, Seita Kondo, Kohei Wakabayashi, Satoru Suwa, Tomotaka Dohi, Hiroyoshi Mori, Shigeki Kimura, Satoru Mitomo, Sunao Nakamura, Takumi Higuma, Junichi Yamaguchi, Makoto Natsumeda, Yuji Ikari, Jun Yamashita, Takehiko Sambe, Sakiko Yasuhara, Takuya Mizukami, Myong Hwa Yamamoto, Tetsuo Sasano, Toshiro Shinke","doi":"10.1253/circj.CJ-24-0111","DOIUrl":"https://doi.org/10.1253/circj.CJ-24-0111","url":null,"abstract":"<p><strong>Background: </strong>Recent studies suggest that the presence of calcified nodules (CN) is associated with worse prognosis in patients with acute coronary syndrome (ACS). We investigated clinical predictors of optical coherence tomography (OCT)-defined CN in ACS patients in a prospective multicenter registry.Methods and Results: We investigated 695 patients enrolled in the TACTICS registry who underwent OCT assessment of the culprit lesion during primary percutaneous coronary intervention. OCT-CN was defined as calcific nodules erupting into the lumen with disruption of the fibrous cap and an underlying calcified plate. Compared with patients without OCT-CN, patients with OCT-CN (n=28) were older (mean [±SD] age 75.0±11.3 vs. 65.7±12.7 years; P<0.001), had a higher prevalence of diabetes (50.0% vs. 29.4%; P=0.034), hemodialysis (21.4% vs. 1.6%; P<0.001), and Killip Class III/IV heart failure (21.4% vs. 5.7%; P=0.003), and a higher preprocedural SYNTAX score (median [interquartile range] score 15 [11-25] vs. 11 [7-19]; P=0.003). On multivariable analysis, age (odds ratio [OR] 1.072; P<0.001), hemodialysis (OR 16.571; P<0.001), and Killip Class III/IV (OR 4.466; P=0.004) were significantly associated with the presence of OCT-CN. In non-dialysis patients (n=678), age (OR 1.081; P<0.001), diabetes (OR 3.046; P=0.014), and Killip Class III/IV (OR 4.414; P=0.009) were significantly associated with the presence of OCT-CN.</p><p><strong>Conclusions: </strong>The TACTICS registry shows that OCT-CN is associated with lesion severity and poor clinical background, which may worsen prognosis.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Echocardiographic Parameters of Left Atrial Structure and Function and Clinical Outcomes at 2 Years in Elderly Patients With Atrial Fibrillation - The ANAFIE Echocardiographic Substudy. 老年心房颤动患者2年左心房结构和功能的超声心动图参数及临床结果——ANAFIE超声心动图子研究。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-10-28 DOI: 10.1253/circj.CJ-23-0084
Ken-Ichi Hiasa, Hidetaka Kaku, Hiroshi Inoue, Takeshi Yamashita, Masaharu Akao, Hirotsugu Atarashi, Takanori Ikeda, Yukihiro Koretsune, Ken Okumura, Wataru Shimizu, Shinya Suzuki, Kazunori Toyoda, Atsushi Hirayama, Masahiro Yasaka, Takenori Yamaguchi, Satoshi Teramukai, Tetsuya Kimura, Yoshiyuki Morishima, Atsushi Takita, Hiroyuki Tsutsui
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引用次数: 0
Role of Implantable Cardioverter Defibrillators in Patients With Heart Failure and Nonischemic Cardiomyopathy in Japan - Analysis From the Nippon Storm Study. 植入式心律转复除颤器在日本心力衰竭和非缺血性心肌病患者中的作用——来自日本风暴研究的分析
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-12-07 DOI: 10.1253/circj.CJ-23-0783
Toshiko Nakai
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引用次数: 0
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