Circulation Journal最新文献

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Premature Ventricular Complexes and Epicardial Adipose Tissue - A Fatty and Funny Relationship. 室性早搏与心外膜脂肪组织--肥胖与有趣的关系
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-12-13 DOI: 10.1253/circj.CJ-23-0825
Ichitaro Abe, Naohiko Takahashi
{"title":"Premature Ventricular Complexes and Epicardial Adipose Tissue - A Fatty and Funny Relationship.","authors":"Ichitaro Abe, Naohiko Takahashi","doi":"10.1253/circj.CJ-23-0825","DOIUrl":"10.1253/circj.CJ-23-0825","url":null,"abstract":"","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138813070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracellular Volume Analysis Using Computed Tomography Is Useful for Follow-up of Takotsubo Syndrome. 利用计算机断层扫描分析细胞外容积有助于随访塔克次氏综合征
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-04-27 DOI: 10.1253/circj.CJ-24-0139
Yusei Nishikawa, Hiroyuki Takaoka, Ken Kato, Joji Ota, Yoshitada Noguchi, Shuhei Aoki, Moe Matsumoto, Satomi Yashima, Katsuya Suzuki, Kazuki Yoshida, Makiko Kinoshita, Haruka Sasaki, Noriko Suzuki-Eguchi, Yoshio Kobayashi
{"title":"Extracellular Volume Analysis Using Computed Tomography Is Useful for Follow-up of Takotsubo Syndrome.","authors":"Yusei Nishikawa, Hiroyuki Takaoka, Ken Kato, Joji Ota, Yoshitada Noguchi, Shuhei Aoki, Moe Matsumoto, Satomi Yashima, Katsuya Suzuki, Kazuki Yoshida, Makiko Kinoshita, Haruka Sasaki, Noriko Suzuki-Eguchi, Yoshio Kobayashi","doi":"10.1253/circj.CJ-24-0139","DOIUrl":"10.1253/circj.CJ-24-0139","url":null,"abstract":"","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome. 动态心电图预测长QT综合征患儿预后的方法。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-12-01 DOI: 10.1253/circj.CJ-23-0409
Masao Yoshinaga, Yumiko Ninomiya, Yuji Tanaka, Megumi Fukuyama, Koichi Kato, Seiko Ohno, Minoru Horie, Hiromitsu Ogata
{"title":"Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome.","authors":"Masao Yoshinaga, Yumiko Ninomiya, Yuji Tanaka, Megumi Fukuyama, Koichi Kato, Seiko Ohno, Minoru Horie, Hiromitsu Ogata","doi":"10.1253/circj.CJ-23-0409","DOIUrl":"10.1253/circj.CJ-23-0409","url":null,"abstract":"<p><strong>Background: </strong>This study was performed to clarify the clinical findings of pediatric patients diagnosed with long QT syndrome (LQTS) through electrocardiographic screening programs and to predict their outcome using Holter electrocardiographic approaches.</p><p><strong>Methods and results: </strong>This retrospective study included pediatric patients with a Schwartz score of ≥3.5 who visited the National Hospital Organization Kagoshima Medical Center between April 2005 and March 2019. Resting 12-lead and Holter electrocardiograms were recorded at every visit. The maximum resting QTc and maximum Holter QTc values among all recordings were used for statistical analyses. To test the prognostic value of QTc for the appearance of cardiac events after the first hospital visit, receiver operating characteristic curves were used to calculate the area under the curve (AUC). Among 207 patients, 181 (87%) were diagnosed through screening programs. The prevalence of cardiac events after the first hospital visit was 4% (8/207). Among QTc at diagnosis, maximum resting QTc, and maximum Holter QTc, only maximum Holter QTc value was a predictor (P=0.02) of cardiac events after the hospital visit in multivariate regression analysis. The AUC of the maximum Holter QTc was significantly superior to that of maximum resting QTc.</p><p><strong>Conclusions: </strong>The maximum Holter QTc value can be used to predict the appearance of symptoms in pediatric patients with LQTS.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138479175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Significance of Atrial Tachyarrhythmia Duration for Ventricular Arrhythmia in Patients With Cardiac Resynchronization Therapy. 心脏再同步化治疗对室性心律失常患者房性心动过速持续时间的临床意义。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-12-05 DOI: 10.1253/circj.CJ-23-0547
Nobuhiko Ueda, Takashi Noda, Koshiro Kanaoka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kenichiro Yamagata, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takeshi Aiba, Hideaki Kanzaki, Chisato Izumi, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano
{"title":"Clinical Significance of Atrial Tachyarrhythmia Duration for Ventricular Arrhythmia in Patients With Cardiac Resynchronization Therapy.","authors":"Nobuhiko Ueda, Takashi Noda, Koshiro Kanaoka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kenichiro Yamagata, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takeshi Aiba, Hideaki Kanzaki, Chisato Izumi, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano","doi":"10.1253/circj.CJ-23-0547","DOIUrl":"10.1253/circj.CJ-23-0547","url":null,"abstract":"<p><strong>Background: </strong>Atrial tachyarrhythmias (ATAs) are reportedly associated with ventricular arrhythmias (VAs). However, little is known about the association between ATA duration and the risk of VA. We investigated the relationship between ATA duration and subsequent VA in patients with a cardiac resynchronization therapy defibrillator (CRT-D).</p><p><strong>Methods and results: </strong>We investigated associations between the longest ATA duration during the first year after cardiac resynchronization therapy (CRT) implantation and VA and VA relevant to ATA (VAATA) in 160 CRT-D patients. ATAs occurred in 63 patients in the first year. During a median follow-up of 925 days from 1 year after CRT implantation, 40 patients experienced 483 VAs. Kaplan-Meier analysis showed a significantly higher risk of VA in patients with than without ATA in the first year (log rank P=0.0057). Hazard ratios (HR) of VA (HR 2.36, 2.10, and 3.04 for ATA >30s, >6 min and >24 h, respectively) and only VAATA (HR 4.50, 5.59, and 11.79 for ATA >30s, >6 min and >24 h, respectively) increased according to the duration of ATA. In multivariate analysis, ATA >24 h was an independent predictor of subsequent VA (HR 2.42; P=0.02).</p><p><strong>Conclusions: </strong>Patients with ATA >24 h in the first year after CRT had a higher risk of subsequent VA and VAATA. The risk of VA, including VAATA, increased with the longest ATA duration.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Vein Intervention for Severe Pulmonary Vein Stenosis After Atrial Fibrillation Ablation - A Retrospective Cohort Study. 心房颤动消融术后严重肺静脉狭窄的肺静脉介入治疗--一项回顾性队列研究。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-03-16 DOI: 10.1253/circj.CJ-23-0892
Kensuke Yokoi, Tomonori Katsuki, Takanori Yamaguchi, Toyokazu Otsubo, Yoshimitsu Soga, Kenichi Hiroshima, Shinjo Sonoda, Koichi Node
{"title":"Pulmonary Vein Intervention for Severe Pulmonary Vein Stenosis After Atrial Fibrillation Ablation - A Retrospective Cohort Study.","authors":"Kensuke Yokoi, Tomonori Katsuki, Takanori Yamaguchi, Toyokazu Otsubo, Yoshimitsu Soga, Kenichi Hiroshima, Shinjo Sonoda, Koichi Node","doi":"10.1253/circj.CJ-23-0892","DOIUrl":"10.1253/circj.CJ-23-0892","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary vein (PV) stenosis (PVS) is a serious complication of atrial fibrillation (AF) ablation. The objective of this study was to describe interventional treatments for PVS after AF ablation and long-term outcomes in Japanese patients.</p><p><strong>Methods and results: </strong>This multicenter retrospective observational study enrolled 30 patients (26 [87%] male; median age 55 years) with 56 severe PVS lesions from 43 PV interventional procedures. Twenty-seven (90%) patients had symptomatic PVS and 19 (63%) had a history of a single AF ablation. Of the 56 lesions, 41 (73%) were de novo lesions and 15 (27%) were retreated. Thirty-three (59%) lesions were treated with bare metal stents, 14 (25%) were treated with plain balloons, and 9 (16%) were treated with drug-coated balloons. All lesions were successfully treated without any systemic embolic event. Over a median follow-up of 584 days (interquartile range 265-1,165 days), restenosis rates at 1 and 2 years were 35% and 47%, respectively. Multivariate Cox regression analysis revealed devices <7 mm in diameter (hazard ratio [HR] 2.52; 95% confidence interval [CI] 1.04-6.0; P=0.040) and totally occluded lesions (HR 3.33; 95% CI 1.21-9.15; P=0.020) were independent risk factors for restenosis.</p><p><strong>Conclusions: </strong>All PVS lesions were successfully enlarged by the PV intervention; however, restenosis developed in approximately half the lesions within 2 years.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinical Course of Fast-Growing Myxoma - Echocardiography and Computed Tomography Observation. 快速生长肌瘤的临床病程--超声心动图和计算机断层扫描观察。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-05-14 DOI: 10.1253/circj.CJ-24-0006
Ryo Horita, Makoto Hashimoto, Yuhei Kasai, Ryo Otake, Hidemasa Shitan, Daisuke Hachinohe, Tsutomu Fujita
{"title":"The Clinical Course of Fast-Growing Myxoma - Echocardiography and Computed Tomography Observation.","authors":"Ryo Horita, Makoto Hashimoto, Yuhei Kasai, Ryo Otake, Hidemasa Shitan, Daisuke Hachinohe, Tsutomu Fujita","doi":"10.1253/circj.CJ-24-0006","DOIUrl":"10.1253/circj.CJ-24-0006","url":null,"abstract":"","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140946361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Sleep Apnea on Nocturnal Parasympathetic Activity in Atrial Fibrillation Patients After Catheter Ablation - Implications for Heart Rate Variability Analysis. 导管消融术后睡眠呼吸暂停对心房颤动患者夜间副交感神经活动的影响--对心率变异性分析的启示
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-01-27 DOI: 10.1253/circj.CJ-23-0682
Hibiki Iwakoshi, Yusuke C Asada, Mitsuko Nakata, Masahiro Makino, Jun Munakata, Nobunari Tomura, Satoshi Shimoo, Tetsuro Nishimura, Hirokazu Shiraishi, Satoaki Matoba, Keitaro Senoo
{"title":"Impact of Sleep Apnea on Nocturnal Parasympathetic Activity in Atrial Fibrillation Patients After Catheter Ablation - Implications for Heart Rate Variability Analysis.","authors":"Hibiki Iwakoshi, Yusuke C Asada, Mitsuko Nakata, Masahiro Makino, Jun Munakata, Nobunari Tomura, Satoshi Shimoo, Tetsuro Nishimura, Hirokazu Shiraishi, Satoaki Matoba, Keitaro Senoo","doi":"10.1253/circj.CJ-23-0682","DOIUrl":"10.1253/circj.CJ-23-0682","url":null,"abstract":"<p><strong>Background: </strong>The impact of sleep apnea (SA) on heart rate variability (HRV) in atrial fibrillation (AF) patients has not been investigated.</p><p><strong>Methods and results: </strong>Of 94 patients who underwent AF ablation between January 2021 and September 2022, 76 patients who had a nocturnal Holter electrocardiography and polysomnography conducted simultaneously were included in the analysis. A 15-min duration of HRV, as determined by an electrocardiogram during apnea and non-apnea time, were compared between patients with and without AF recurrence at 12 months' postoperatively. Patients had a mean age of 63.4±11.6 years, 14 were female, and 20 had AF recurrence at 12 months' follow-up. The root mean square of the difference between consecutive normal-to-normal intervals (RMSSD, ms) an indicator of a parasympathetic nervous system, was more highly increased in patients with AF recurrence than those without, during both apnea and non-apnea time (apnea time: 16.7±4.5 vs. 13.5±3.3, P=0.03; non-apnea time: 20.9±9.5 vs. 15.5±5.9, P<0.01). However, RMSSD during an apneic state was decreased more than that in a non-apneic state in both groups of patients with and without AF recurrence (AF recurrence group: 16.7±4.5 vs. 20.9±9.5, P<0.01; non-AF recurrence group; 13.5±3.3 vs. 15.5±5.9, P=0.03). Consequently, the effect of AF recurrence on parasympathetic activity was offset by SA. Similar trends were observed for other parasympathetic activity indices; high frequency (HF), logarithm of HF (lnHF) and the percentage of normal-to-normal intervals >50 ms (pNN50).</p><p><strong>Conclusions: </strong>Without considering the influence of SA, the results of nocturnal HRV analysis might be misinterpreted. Caution should be taken when using nocturnal HRV as a predictor of AF recurrence.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139572030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of Auto-Quantified Epicardial Adipose Tissue in Predicting Atrial Fibrillation Recurrence After Catheter Ablation. 自动量化心外膜脂肪组织预测导管消融术后心房颤动复发的可行性
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-02-14 DOI: 10.1253/circj.CJ-23-0808
Ling Kuo, Guan-Jie Wang, Shih-Ling Chang, Yenn-Jiang Lin, Fa-Po Chung, Li-Wei Lo, Yu-Feng Hu, Tze-Fan Chao, Ta-Chuan Tuan, Jo-Nan Liao, Ting-Yung Chang, Chin-Yu Lin, Chih-Min Liu, Shin-Huei Liu, Ming-Ren Kuo, Guan-Yi Li, Yu-Shan Huang, Cheng-I Wu, Shih-Ann Chen, Chia-Feng Lu
{"title":"Feasibility of Auto-Quantified Epicardial Adipose Tissue in Predicting Atrial Fibrillation Recurrence After Catheter Ablation.","authors":"Ling Kuo, Guan-Jie Wang, Shih-Ling Chang, Yenn-Jiang Lin, Fa-Po Chung, Li-Wei Lo, Yu-Feng Hu, Tze-Fan Chao, Ta-Chuan Tuan, Jo-Nan Liao, Ting-Yung Chang, Chin-Yu Lin, Chih-Min Liu, Shin-Huei Liu, Ming-Ren Kuo, Guan-Yi Li, Yu-Shan Huang, Cheng-I Wu, Shih-Ann Chen, Chia-Feng Lu","doi":"10.1253/circj.CJ-23-0808","DOIUrl":"10.1253/circj.CJ-23-0808","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to build an auto-segmented artificial intelligence model of the atria and epicardial adipose tissue (EAT) on computed tomography (CT) images, and examine the prognostic significance of auto-quantified left atrium (LA) and EAT volumes for AF.</p><p><strong>Methods and results: </strong>This retrospective study included 334 patients with AF who were referred for catheter ablation (CA) between 2015 and 2017. Atria and EAT volumes were auto-quantified using a pre-trained 3-dimensional (3D) U-Net model from pre-ablation CT images. After adjusting for factors associated with AF, Cox regression analysis was used to examine predictors of AF recurrence. The mean (±SD) age of patients was 56±11 years; 251 (75%) were men, and 79 (24%) had non-paroxysmal AF. Over 2 years of follow-up, 139 (42%) patients experienced recurrence. Diabetes, non-paroxysmal AF, non-pulmonary vein triggers, mitral line ablation, and larger LA, right atrium, and EAT volume indices were linked to increased hazards of AF recurrence. After multivariate adjustment, non-paroxysmal AF (hazard ratio [HR] 0.6; 95% confidence interval [CI] 0.4-0.8; P=0.003) and larger LA-EAT volume index (HR 1.1; 95% CI 1.0-1.2; P=0.009) remained independent predictors of AF recurrence.</p><p><strong>Conclusions: </strong>LA-EAT volume measured using the auto-quantified 3D U-Net model is feasible for predicting AF recurrence after CA, regardless of AF type.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appropriate Selection of Substrate Ablation for Persistent Atrial Fibrillation Using Intraprocedural Assessment. 利用术中评估为持续性心房颤动选择适当的基底消融。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2024-05-30 DOI: 10.1253/circj.CJ-23-0936
Yasuharu Matsunaga-Lee, Koichi Inoue, Nobuaki Tanaka, Masaharu Masuda, Tetsuya Watanabe, Nobuhiko Makino, Yasuyuki Egami, Takafumi Oka, Hitoshi Minamiguchi, Miwa Miyoshi, Masato Okada, Takashi Kanda, Yasuhiro Matsuda, Masato Kawasaki, Shodai Kawanami, Hiroki Sugae, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Masaki Tsuda, Naotaka Okamoto, Masamichi Yano, Masami Nishino, Akihiro Sunaga, Yohei Sotomi, Tomoharu Dohi, Daisaku Nakatani, Shungo Hikoso, Yasushi Sakata
{"title":"Appropriate Selection of Substrate Ablation for Persistent Atrial Fibrillation Using Intraprocedural Assessment.","authors":"Yasuharu Matsunaga-Lee, Koichi Inoue, Nobuaki Tanaka, Masaharu Masuda, Tetsuya Watanabe, Nobuhiko Makino, Yasuyuki Egami, Takafumi Oka, Hitoshi Minamiguchi, Miwa Miyoshi, Masato Okada, Takashi Kanda, Yasuhiro Matsuda, Masato Kawasaki, Shodai Kawanami, Hiroki Sugae, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Masaki Tsuda, Naotaka Okamoto, Masamichi Yano, Masami Nishino, Akihiro Sunaga, Yohei Sotomi, Tomoharu Dohi, Daisaku Nakatani, Shungo Hikoso, Yasushi Sakata","doi":"10.1253/circj.CJ-23-0936","DOIUrl":"10.1253/circj.CJ-23-0936","url":null,"abstract":"<p><strong>Background: </strong>It has not been fully elucidated which patients with persistent atrial fibrillation (PerAF) should undergo substrate ablation plus pulmonary vein isolation (PVI). This study aimed to identify PerAF patients who required substrate ablation using intraprocedural assessment of the baseline rhythm and the origin of atrial fibrillation (AF) triggers.</p><p><strong>Methods and results: </strong>This was a post hoc subanalysis using extended data of the EARNEST-PVI trial, a prospective multicenter randomized trial comparing PVI-alone and PVI-plus (i.e., PVI with added catheter ablation) arms. We divided 492 patients into 4 groups according to baseline rhythm and the location of AF triggers before PVI: Group A (n=22), sinus rhythm with pulmonary vein (PV)-specific AF triggers (defined as reproducible AF initiation from PVs only); Group B (n=211), AF with PV-specific AF triggers; Group C (n=94), sinus rhythm with no PV-specific AF trigger; Group D (n=165), AF with no PV-specific AF trigger. Among the 4 groups, only in Group D (AF at baseline and no PV-specific AF triggers) was arrhythmia-free survival significantly lower in the PVI-alone than PVI-plus arm (P=0.032; hazard ratio 1.68; 95% confidence interval 1.04-2.70).</p><p><strong>Conclusions: </strong>Patients with sinus rhythm or PV-specific AF triggers did not receive any benefit from substrate ablation, whereas patients with AF and no PV-specific AF trigger benefited from substrate ablation.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between Epicardial Adipose Tissue Volume and Recurrence After Ablation in Premature Ventricular Complexes. 心外膜脂肪组织体积与早搏心室复合体消融后复发的关系。
IF 3.1 3区 医学
Circulation Journal Pub Date : 2024-06-25 Epub Date: 2023-11-01 DOI: 10.1253/circj.CJ-23-0474
Zhe Wang, Jiaju Li, Jiawei Chen, Hehe Guo, Haoming He, Siqi Jiao, Yingwei Chen, Jianzeng Dong, Yihong Sun
{"title":"Relationship Between Epicardial Adipose Tissue Volume and Recurrence After Ablation in Premature Ventricular Complexes.","authors":"Zhe Wang, Jiaju Li, Jiawei Chen, Hehe Guo, Haoming He, Siqi Jiao, Yingwei Chen, Jianzeng Dong, Yihong Sun","doi":"10.1253/circj.CJ-23-0474","DOIUrl":"10.1253/circj.CJ-23-0474","url":null,"abstract":"<p><strong>Background: </strong>Epicardial adipose tissue (EAT) is recognized as a clinical diagnostic marker for cardiometabolic disease. Thicker EAT may be associated with recurrence of ventricular tachycardia after ablation. The association between EAT volume and recurrence of premature ventricular complexes (PVC) following ablation has not been clarified. We investigated the association between EAT volume and PVC recurrence following radiofrequency catheter ablation.</p><p><strong>Methods and results: </strong>This retrospective study included 401 patients with PVC undergoing catheter ablation with preprocedural non-contrast computed tomography between 2017 and 2022. The impact of EAT volume in predicting PVC recurrence after ablation was analyzed. The mean (±SD) age of patients was 50.2±13.3 years. Multivariable Cox analysis revealed that a large EAT volume was an independent predictor of PVC recurrence after ablation during a median follow-up of 16.3 months. Kaplan-Meier analysis showed a difference in postablation PVC recurrence between the 2 groups dichotomized around the EAT volume cut-off. The risk of recurrence increased with increasing EAT volume according to restricted cubic spline regression. Furthermore, PVC originating from epicardial locations had larger EAT volumes than those originating from the right ventricular outflow tract.</p><p><strong>Conclusions: </strong>A large EAT volume was independently associated with PVC recurrence following ablation. Patients with PVC originating from epicardial sites had large EAT volumes. EAT volume may help stratify patients according to their risk of PVC recurrence after ablation.</p>","PeriodicalId":50691,"journal":{"name":"Circulation Journal","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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