Clinical ImagingPub Date : 2025-05-30DOI: 10.1016/j.clinimag.2025.110526
Lee Collins , Felipe Camelo , Sara Cohen , Arzu Kovanlikaya , Delma Y. Jarrett
{"title":"Subdural collections in the neonatal ICU: Assessment using high frequency sonography","authors":"Lee Collins , Felipe Camelo , Sara Cohen , Arzu Kovanlikaya , Delma Y. Jarrett","doi":"10.1016/j.clinimag.2025.110526","DOIUrl":"10.1016/j.clinimag.2025.110526","url":null,"abstract":"<div><h3>Background</h3><div>Subdural collections (SDC) in the neonate are most often diagnosed on CT and MR as birth related subdural hematoma. With the use of high frequency linear ultrasound (US) transducers, SDC have been seen with increased frequency by US in our NICU population.</div></div><div><h3>Objective</h3><div>The aim is to determine the prevalence of SDC on US in our NICU population and to assess whether changes in US transducer frequency effects detection.</div></div><div><h3>Materials/methods</h3><div>A retrospective review was conducted of head US in our NICU between August 2020 and March 2021. All scans were done using the anterior fontanelle approach. Included exams had cine clips with 1) full brain field of view (FOV) with linear 2–9 MHz transducer, and 2) superficial FOV with either linear 2–9 or 6–24 MHz transducer. Images were assessed for presence of SDC and if present echogenicity of the SDC relative to the subarachnoid fluid.</div></div><div><h3>Results</h3><div>142 US exams met inclusion criteria. SDC were identified in 10 patients, on 15 studies. For patients with SDC, median gestational age at birth was 31.3 weeks (versus 34.4 weeks in patients without SDC). SDC were only identified on superficial FOV cine clips performed with the 6–24 MHz transducer, and all were anechoic. Earlier gestational age and thrombocytopenia were associated with SDC.</div></div><div><h3>Conclusion</h3><div>Small anechoic subdural collections can be visualized in head US exams in NICU patients; however, their detection is highly dependent on the use of very high frequency linear transducer with small FOV imaging.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110526"},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-30DOI: 10.1016/j.clinimag.2025.110525
Hana Haver , Manisha Bahl , Maggie Chung
{"title":"Classifying the clinical significance of common breast pain symptoms using a large language model, ChatGPT (GPT-4)","authors":"Hana Haver , Manisha Bahl , Maggie Chung","doi":"10.1016/j.clinimag.2025.110525","DOIUrl":"10.1016/j.clinimag.2025.110525","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"125 ","pages":"Article 110525"},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-30DOI: 10.1016/j.clinimag.2025.110528
Choong-Wui Cho , Myung-Won You , Munyoung Paek , Dominik Nickel , Sung Kyoung Moon
{"title":"Deep learning reconstruction for T2-weighted and contrast-enhanced T1-weighted magnetic resonance enterography imaging in patients with Crohn's disease: Assessment of image quality and clinical utility","authors":"Choong-Wui Cho , Myung-Won You , Munyoung Paek , Dominik Nickel , Sung Kyoung Moon","doi":"10.1016/j.clinimag.2025.110528","DOIUrl":"10.1016/j.clinimag.2025.110528","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the image quality of deep learning-reconstructed T2-weighted half-Fourier single-shot turbo spin echo (DL T2 HASTE) and contrast-enhanced T1-weighted volumetric interpolated breath-hold examination (DL T1 VIBE) of magnetic resonance enterography in patients with Crohn's disease.</div></div><div><h3>Methods</h3><div>Ninety-three patients for the comparison between T2 HASTE and DL T2 HASTE, and forty-two patients for the comparison between T1 VIBE and DL T1 VIBE were enrolled. Two reviewers assessed image quality using 5-point scale scoring, and subjective reviewer preferences. Acquisition times were also compared. The diagnostic performance for the detection of active inflammation was evaluated in three bowel segments (ileum, terminal ileum, and right colon).</div></div><div><h3>Results</h3><div>The interobserver agreement on image quality was better for T2 HASTE (0.624, standard error 0.083), and T1 VIBE (0.53, SE 0.113) than for DL T2 HASTE (0.443, SE 0.111) and DL T1 VIBE (0.173, SE 0.153). The mean image quality scores showed no significant differences between T2 HASTE and DL T2 HASTE images, as well as between T1 VIBE and DL T1 VIBE images (<em>p</em> > 0.05). Both reviewers preferred T2 HASTE over DL T2 HASTE, although the preference between T1 VIBE and DL T1 VIBE was controversial. The acquisition times were shorter for DL T2 HASTE (16.17 ± 2.53 s) and DL T1 VIBE (14.19 ± 0.84 s) compared to T2 HASTE and T1 VIBE. The per-segment diagnostic performance for detecting active inflammation was identical between T2 HASTE and DL T2 HASTE.</div></div><div><h3>Conclusion</h3><div>DL-reconstruction allows one-breath hold scan while maintaining image quality in both T2 HASTE and T1 VIBE images.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110528"},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-29DOI: 10.1016/j.clinimag.2025.110524
Ozden Kilinc , Jay Bharat Bisen , Anthony Maroun , Ethan Johnson , Sandra Quinn , Daniel Kim , Daniel C. Lee , Michael Markl , Bradley D. Allen
{"title":"4D Flow MRI derived aortic pulse wave velocity and wall shear stress in Covid-19","authors":"Ozden Kilinc , Jay Bharat Bisen , Anthony Maroun , Ethan Johnson , Sandra Quinn , Daniel Kim , Daniel C. Lee , Michael Markl , Bradley D. Allen","doi":"10.1016/j.clinimag.2025.110524","DOIUrl":"10.1016/j.clinimag.2025.110524","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to investigate the changes in aortic pulse wave velocity (PWV) and wall shear stress (WSS) in COVID-19 using 4D Flow MRI.</div></div><div><h3>Methods</h3><div>Thirty-seven COVID-19 patients and 37 healthy controls underwent thoracic cardiovascular MRI. The PWV and WSS comparisons were performed using independent <em>t</em>-test. Peak velocity (PV)-peak WSS correlations in patients; aortic dimension-regional WSS correlations; PWV-age correlations were reported using Pearson correlation coefficient (r) analysis.</div></div><div><h3>Results</h3><div>The global aortic PWV was higher in the patient group (<em>p</em> = 0.007). There was a positive correlation between patient age and PWV values (<em>r</em> = 0.650, <em>p</em> = 0.000). The patient ascending aorta (AAo) WSS levels were lower in the entire cohort, in the subgroup of ages between 50 and 70, and in the age/gender matched subgroup (<em>p</em> < 0.05 for all). Voxelwise 5 % PV was lower in the patient group (<em>p</em> = 0.005) and showed strong correlation with the 5 % peak WSS (<em>r</em> = 0.957). In the patient group there was a negative correlation between the maximal aortic dimension and AAo WSS (<em>r</em> = −0.398, <em>p</em> = 0.014) and aortic arch WSS (<em>r</em> = −0.388, <em>p</em> = 0.017).</div></div><div><h3>Conclusion</h3><div>The alterations to aortic stiffness in COVID-19 might be a late effect of the disease and should be confirmed in larger studies with longer follow-ups. The reasons behind the low AAo WSS levels in the COVID-19 group appears to be multifactorial and further work in larger cohorts eliminating the baseline aortic diameter and preexisting atherosclerotic risk factor differences is needed to validate our results and to establish reproducibility of the technique.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110524"},"PeriodicalIF":1.8,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-28DOI: 10.1016/j.clinimag.2025.110523
Ricardo Martinez Garcia , Rajoo Dhangana , Will S. Lindquester
{"title":"Percutaneous thermal and cryoablation of lung masses compared to sub-lobar lung resection: Medicare trends from 2012 to 2021","authors":"Ricardo Martinez Garcia , Rajoo Dhangana , Will S. Lindquester","doi":"10.1016/j.clinimag.2025.110523","DOIUrl":"10.1016/j.clinimag.2025.110523","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze trends in Medicare volume and utilization for percutaneous ablation of lung masses compared to sub-lobar surgical lung resection.</div></div><div><h3>Methods</h3><div>Claims from the Medicare Part B Physician/Supplier Procedure Summary from 2012 to 2021 were extracted using Current Procedural Terminology (CPT) codes for percutaneous lung thermal ablation (radiofrequency (RFA) and microwave) and cryoablation as well as open and Video Assisted Thoracoscopic (VATS) sub-lobar lung resection.</div></div><div><h3>Results</h3><div>The volume of lung mass ablation decreased from 601 cases (thermal ablation only) in 2012 to 466 cases (240 RFA and 226 cryoablation) in 2021 amongst Medicare beneficiaries. Utilization of lung mass ablation decreased from 1.18 procedures (RFA only) per 100,000 Medicare beneficiaries in 2012 to 0.74 procedures (0.38 for thermal ablation and 0.36 for cryoablation) per 100,000 beneficiaries in 2021.</div><div>From the inception of the CPT code for lung cryoablation in 2018, the volume increased from 192 to 226 procedures in 2021.</div><div>The volume for open sub-lobar lung resection decreased markedly over the study period, decreasing from 8114 procedure (15.96 per 100,000 Medicare beneficiaries) in 2012 to 2668 procedure (4.26 per 100,000 Medicare beneficiaries) in 2021. The volume of VATS sub-lobar lung resection increased from 14,279 procedures in 2012 to 15,978 procedures in 2021, but utilization per 100,000 Medicare beneficiaries decreased from 28.09 to 25.52 due to growth in Medicare enrollees.</div></div><div><h3>Conclusion</h3><div>Very low utilization of all percutaneous ablation of lung masses decreased from 2012 to 2021. Nevertheless, the low volume of percutaneous cryoablation has grown since 2018.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"125 ","pages":"Article 110523"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-28DOI: 10.1016/j.clinimag.2025.110527
Kieran Howard, Hasaam Uldin, Rajesh Botchu
{"title":"Costochondral junction lesions: A retrospective review of 126 cases, pictorial imaging findings, and a proposed age-based diagnostic algorithm","authors":"Kieran Howard, Hasaam Uldin, Rajesh Botchu","doi":"10.1016/j.clinimag.2025.110527","DOIUrl":"10.1016/j.clinimag.2025.110527","url":null,"abstract":"<div><h3>Background</h3><div>Lesions affecting the costochondral junction are rare and present diagnostic challenges due to a wide differential diagnosis encompassing bone, cartilage, and adjacent soft tissue structures. This article summarises one of the largest published datasets on this topic from a single-centre tertiary referral centre, and reviews the existing literature to provide case examples and age-stratified diagnostic algorithms.</div></div><div><h3>Methods</h3><div>We conducted a retrospective review of 126 cases identified between 2007 and 2024 from the institutional oncology database of a tertiary orthopaedic hospital, primarily receiving adult referrals. Cases were evaluated based on clinical, imaging, and histopathological findings using the local CRIS and PACS. Lesions were classified according to the 2020 WHO classification of bone tumours.</div></div><div><h3>Results</h3><div>The mean age was 49 (range: 7 to 85 years old). Of the 126 total cases, 42 cases (33 %) occurred in those under the age of 40, and 84 cases (67 %) were in those 40 and over. No malignant lesions were found in the under 40 years of age. Structural abnormalities predominated (65.0 %), followed by benign lesions (16.0 %) and malignant lesions (19.0 %), with chondrosarcoma being the most common malignancy.</div></div><div><h3>Conclusion</h3><div>Although most lesions are benign or structural, malignancy must be actively considered, particularly in older patients. An algorithmic approach to evaluation, incorporating clinical, imaging, and histological data, can support timely and accurate diagnosis.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110527"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-23DOI: 10.1016/j.clinimag.2025.110513
C. Jaramillo, S. Tabaza, E. Ferguson, E. Odisio, D. Ocazionez, C. Duran, B. Akkanti, M. Awiwi, M. Hanna
{"title":"Response to the letter to the editor: “Differential diagnosis of pulmonary artery obstructions”","authors":"C. Jaramillo, S. Tabaza, E. Ferguson, E. Odisio, D. Ocazionez, C. Duran, B. Akkanti, M. Awiwi, M. Hanna","doi":"10.1016/j.clinimag.2025.110513","DOIUrl":"10.1016/j.clinimag.2025.110513","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110513"},"PeriodicalIF":1.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-23DOI: 10.1016/j.clinimag.2025.110511
Fardad Behzadi , Bilal Siddiq , Zhou Lan , Yan Epelboym
{"title":"Evaluating the association between knee osteoarthritis severity and descending genicular artery caliber","authors":"Fardad Behzadi , Bilal Siddiq , Zhou Lan , Yan Epelboym","doi":"10.1016/j.clinimag.2025.110511","DOIUrl":"10.1016/j.clinimag.2025.110511","url":null,"abstract":"<div><h3>Introduction</h3><div>Genicular artery embolization (GAE) is performed with the intent of reducing a pathologic increase of neovascularity in patients with osteoarthritis (OA) related knee pain. It is unclear whether knee OA is associated with upstream changes in genicular artery caliber. The purpose of this study was to evaluate the relationship between knee OA severity and descending genicular artery (DGA) caliber.</div></div><div><h3>Materials and methods</h3><div>A retrospective review of lower extremity computed tomographic (CT) angiography studies from July 2022 to March 2023 was conducted. Patients with Kellgren-Lawrence (KL) grade 0–4 knee OA were included. The caliber of the descending genicular artery (DGA) and the superficial femoral artery (SFA) at the level of the DGA origin were measured.</div></div><div><h3>Results</h3><div>In the left and right leg respectively, a strong positive correlation was demonstrated between KL grade and DGA caliber (<em>r</em> = 0.68, <em>p</em> < 0.01), (<em>r</em> = 0.59, p < 0.01), and KL grade and DGA/SFA caliber (<em>r</em> = 0.71, p < 0.01), (r = 0.59, p < 0.01). No significant association was demonstrated between SFA caliber and KL grade in the right and left leg, respectively.</div></div><div><h3>Discussion</h3><div>This retrospective study reveals significant positive correlations between the severity of knee OA, and caliber of the DGA. These findings suggest that joint level changes of OA may be associated with upstream changes in genicular artery caliber.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110511"},"PeriodicalIF":1.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-05-20DOI: 10.1016/j.clinimag.2025.110514
Sanda Kolenda Zloić , João Martins da Fonseca , Chukwudi Isaac Ayogu , Karabo Kago Marole , Guilherme Strieder de Oliveira , Marco Aurélio Soato Ratti
{"title":"Prognostic impact of left ventricular strain by feature tracking in acute myocardial infarction treated with PCI: A meta-analysis","authors":"Sanda Kolenda Zloić , João Martins da Fonseca , Chukwudi Isaac Ayogu , Karabo Kago Marole , Guilherme Strieder de Oliveira , Marco Aurélio Soato Ratti","doi":"10.1016/j.clinimag.2025.110514","DOIUrl":"10.1016/j.clinimag.2025.110514","url":null,"abstract":"<div><h3>Purpose</h3><div>To perform a meta-analysis to evaluate the prognostic value of feature tracking (FT)-derived left ventricular (LV) strain parameters in patients following acute myocardial infarction (AMI).</div></div><div><h3>Materials and methods</h3><div>We conducted a comprehensive search of PubMed, Embase, and the Cochrane library for studies published between January 2000 and July 2024, evaluating the prognostic value of FT-derived LV strain parameters in predicting major adverse cardiovascular events (MACE) in patients following AMI. We included studies of patients who underwent cardiac magnetic resonance feature tracking analysis following reperfusion by percutaneous coronary intervention (PCI), as well as reporting multivariate analyses of global longitudinal strain (GLS) or global circumferential strain (GCS). Using RStudio, we calculated pooled hazard ratios (HR) with 95 % confidence intervals (CI) using random-effects models and evaluated heterogeneity with I<sup>2</sup> statistics.</div></div><div><h3>Results</h3><div>Nine studies involving 3651 patients were included. Seven studies focused on GLS, while five evaluated GCS in relation to MACE. The meta-analysis revealed a significant association between GLS and MACE occurrence (HR 1.15; 95 % CI: 1.07–1.23; I<sup>2</sup> = 76 %; <em>p</em> ≤ 0.0001). For GCS, the pooled HR was 1.11 (95 % CI: 1.04–1.19; I<sup>2</sup> = 50 %; <em>p</em> = 0.0024). However, a leave-one-out sensitivity analysis showed that the prognostic effect of GCS was not robust, as the pooled HR adjusted to 1.09 (95 % CI: 1.00–1.19).</div></div><div><h3>Conclusion</h3><div>GLS was identified as a sensitive marker of early myocardial injury with incremental prognostic value, potentially enhancing risk stratification for post-AMI patients. Conversely, GCS did not demonstrate a significant prognostic effect.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"124 ","pages":"Article 110514"},"PeriodicalIF":1.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}