Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology最新文献

{"title":"Nutritional Status of School Adolescents in the Sidi-Bel-Abbes City, Algerian western region","authors":"Hichour, Mokhtaria, D. Mustapha","doi":"10.21608/eajbsc.2024.337308","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.337308","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"24 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139603072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Titanium Dioxide Nanoparticles on the Evaluation of Mint Oil (Mentha Spicata L.) Using some Physiological Analyses and Molecular Markers","authors":"Salma Metwally, Amr Nassar, Hala El-Atroush","doi":"10.21608/eajbsc.2024.336730","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.336730","url":null,"abstract":"To evaluate the impact of Titanium dioxide nanoparticles on pigments, minerals, and essential oil of Mentha spicata L. five treatments of biologically","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"22 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139610890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New N-Substituted Maleimide Drug Polymers: Synthesis, Drug Release and Antibacterial Activity","authors":"Dhuha Kashash, M. Kareem, Naser Naser","doi":"10.21608/eajbsc.2024.336266","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.336266","url":null,"abstract":"In this work, new substituted drugs polymerized as new homogenous polymers with study their medicinal properties to extend the controlled drug. The first step includes the preparation of compound N-(4 - hydroxyphenyl) maleimide (D 1 ) via a reaction of maleic anhydride with 4-aminophenol. Then compound (D 1 ) was converted to maleimide phenol acetic acid ether (D 2 ) which converted to its corresponding acyl chloride derivative which reacted with amino drugs (Ceftriaxone, Ciprofloxacin) afforded monomers (D 3 and D 4 ). Homogeneous polymers (D 5 and D 6 ) were prepared via free radical polymerization reaction of the monomers (D 3 , and D 4 ) under nitrogen using Benzoyl peroxide (Bpo) as initiator. All these prepared monomers and polymers were characterized by FT-IR and 1 H-NMR, 13 C-NMR techniques and C.H.N.S . Study of the drug release behavior in acidic and basic media as well as the swelling ratio were achieved. The antibacterial activity and physical properties of all monomers and polymers were studied.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140503732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eucheuma cottonii Extract Improved The Blood Profile and Kidney Function of Male Albino Rats Induced with Sodium Nitrite (NaNO2)","authors":"Ida Ayu Purnama Dewi, N. I. Wiratmini, Iriani Setyawati","doi":"10.21608/eajbsc.2024.336124","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.336124","url":null,"abstract":"Sodium nitrite (NaNO 2 ) in food preservation causes oxidative stress in the body. Antioxidants are widely used to ward off free radicals caused by oxidative stress. This study aimed to determine the potential of Eucheuma cottonii seaweed extract as a natural antioxidant to improve blood profiles and kidney damage in male albino rats induced by NaNO 2 . This research used a completely randomized design. Thirty animals were divided into five groups, namely negative control, positive control, and three treatment doses of E. cottonii extract. NaNO 2 was dissolved in distilled water, and E. cottonii extract was dissolved in 0.5% CMC-Na solution. The research was conducted for 45 days. The treatment group was given NaNO 2 for 35 days; on days 16 to 45, E. cottonii extract was given at doses of 150, 300, and 450 mg/kg BW. The positive control was given NaNO 2 for 35 days, then given the extract solvent. The negative controls were given the solvent only. At the end of the treatment, the rats were sacrificed to collect blood and kidney organs. The results showed that the extract at doses of 150 and 300 mg/kg BW increased the number of hemoglobin and erythrocytes. The dose of 150 mg/kg BW reduced various kidney damage, such as inflammatory cell infiltration, congestion, hemorrhage, fatty degeneration, necrosis, glomerular abnormalities, and protein deposits in the lumen of the renal tubules. The highest dose of 450 mg/kg BW reduced the number of leukocytes.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"6 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Implication of Altered DKK1/LRP/β-catenin Signaling in Dexamethasone Induced Bone Remodeling Disruption: In Silico and In Vivo Studies in Male Rats","authors":"Adham Maher, Samar Saleh, Doaa Ghareeb, Eman Sheta, Mohamed Nabil, Fatema Younis, Aliaa Masoud","doi":"10.21608/eajbsc.2024.335612","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.335612","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"75 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139530287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variation in Antioxidant Enzymes and Lipid Peroxidation in Response to Gamma Irradiation in Ocimum Basilicum L.","authors":"Shurooq Hassan, Fadhil Alibraheemi, A. Thamir","doi":"10.21608/eajbsc.2024.335095","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.335095","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"24 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139530605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cysteine Cathepsins and Their Diagnostic Role in Breast Cancer","authors":"Mohamed Hosney, Israa Sarhan","doi":"10.21608/eajbsc.2024.334546","DOIUrl":"https://doi.org/10.21608/eajbsc.2024.334546","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"68 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139534739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of the Levels of IL-6, IL-8, and CRP in Women Patients of Osteoporosis and Heart diseases in Samarra city","authors":"Muhannad Majeed, Wijdan Abd-al-Wahab, Mousa M. Marbut","doi":"10.21608/eajbsc.2023.330659","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330659","url":null,"abstract":"A Cross-Sectional study that includes an assessment of the relation of the physiological and immunological factors among postmenopausal women with osteoporosis and heart diseases who attended Samarra General Hospital in Salah AL-Din Governorate The study started from January 2022 to November 2022 on a study population whose ages ranged from 45-70 years, their total number is 100 women, 25 of whom are healthy women who are considered as a control group, and 75 of them are represented by groups of patients that were distributed into three main groups: 25 women with Heart disease only include myocardial infarction and 25 women with osteoporosis only and 25 women with Heart disease and osteoporosis blood samples were collected from patients and healthy subjects and then serum separated for testing. The present study was designed to obtain more clarification of some Immunological changes in women patients with osteoporosis and heart diseases. and find out the role of some Immunological parameters of pro-inflammatory cytokines like Interleukin – 6 IL-6, Interleukin-8 IL-8 and C-reactive protein CRP in the serum of women patients with osteoporosis and heart diseases the result of Immunological parameters include: Interleukin-6, Interleukin IL-8 showed had no significant differences (P≥0.05) in a group of osteoporosis in comparison with the control group and showed significantly increased (P≤0.05) in groups of Heart disease, and osteoporosis with heart disease in comparison with control group. but (CRP) showed a significant increase (P≤0.05) in groups of osteoporosis, Heart disease, and osteoporosis with heart disease in comparison with the control group. To investigate the physiological relationship between Immunological parameters, interleukin 6 and interleukin 8 and high sensitivity C-reactive protein in patients of Osteoporosis and Heart diseases in Samarra city. Serum interleukin-6 and Interleukin IL-8 showed no significant differences (P≥0.05) in the group of osteoporosis in comparison with the control group and showed significantly increased (P≤0.05) in groups of Heart disease, and osteoporosis with heart disease in comparison with the control group , . but (CRP) showed a significant increase (P≤0.05) in groups of osteoporosis, Heart disease, and osteoporosis with heart disease in comparison with the control group.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"32 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Some Food by Product Extracts Compared to Silymarin as Protective Agents against Acute Liver Injury in Paracetamol Overdose-Exposed Rats","authors":"Wafaa Gaballah, Asmaa Faramawy, Samah El-Hashash","doi":"10.21608/eajbsc.2023.330658","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330658","url":null,"abstract":"In paracetamol (PCM) overdose-exposed rats, the hepato-protective properties of ethanolic extracts from grape seeds and peanut skins (GSEE and PSEE, respectively) were compared to silymarin in this study. The total amount of phenolic and flavonoids as well as the ability to scavenge radical DPPH of GSEE and PSEE were measured. Twenty adult male albino rats were split evenly into five groups for the in vivo evaluation; including the control group (GI), while PCM treated group (GII) got paracetamol once orally for 14 days at a dosage of 640 mg/kg/day, with no protective treatment. Silymarin (50 mg /kg /day), and 200 mg /kg /day of either GSEE or PSEE were given concurrently with PCM to GIII, GIV and GV, respectively. PCM overdose led to a significant elevation in the activities of transaminases and alkaline phosphatase (84.00±10.64, 396.00±49.44, and 579.67±72.00 U/L versus 44.00±5.72, 178.00±22.09, and 322.0±40.58 U/L in control group), along with an obvious decline in serum proteins. In the liver, the lipid profile was disrupted associated with a marked elevation in oxidative and inflammation markers, which was further confirmed by histological examination. These disorders were alleviated by the administration of food waste extracts. Even while PSEE showed a little increase in total phenolic, flavonoids and DPPH radical scavenging ability (604.45, 542.05, and 618.59 versus 583.70 mg gallic acid equivalent, 503.80 mg catechin equivalent, and 550.44 mg Trolox equivalent, respectively/g GSEE), GSEE was the nearest treatment when compared to silymarin. This study suggests GSEE and PSEE as alternative therapies for paracetamol-induced hepatotoxicity.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"6 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139167279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Vaginal Microbiota in Infertile Women Compared with Fertile and Evaluation of Correlation Between Elafin As an antimicrobial Peptide with Some Hormones","authors":"Hanade Khalaf, Osama Nijris, A. Hatam, Ali Mahdi","doi":"10.21608/eajbsc.2023.330425","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330425","url":null,"abstract":": This study included the","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"43 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139172871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}