Archives of Current Research International最新文献

{"title":"CG-MS, Radical Scavenging, Acetylcholinesterase Inhibition, Antifungal and Molecular Docking Studies of Essential Oil from the Leaves of Tapirira guianensis Aubl","authors":"Daniel P. de Oliveira, L. S. Frota, S. I. C. G. Barbosa, Francisco F. S. Lopes, José R. G. Neto, Marcia M. Marinho, Emmanuel S. Marinho, Jacilene Silva, J. C. D. Prado, R. Fontenelle, Selene M. de Morais","doi":"10.9734/acri/2024/v24i2635","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2635","url":null,"abstract":"The species Tapirira guianensis Aubl is used in folk medicine to treat leprosy, diarrhea, and syphilis. The present study aims to evaluate the chemical composition and the antioxidant, anticholinesterase, and antifungal potential of the essential oil from T. guianensis leaves. The plant material was collected at Arco Estadual do Cocó, with prior authorization from the Municipal Environment Department. The essential oil was extracted through the hydrodistillation process with a Clevenger-type apparatus, and the constituents were evaluated through Gas Chromatography coupled to Mass Spectrometry (GC-MS). The antioxidant potential was assessed through free radicals: DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS+ (2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) in a 96-well plate. Antifungal activity was evaluated using the Clinical Laboratory Standards Institute - M38-A protocol (CLSI, 2018). Gas chromatography coupled with mass spectrometry revealed the presence of constituents such as eugenol (59.00%), α-copaene (0.40%), β-caryophyllene (29.91%), α-humulene in T. guianensis. The essential oil demonstrated very promising antioxidant and anticholinesterase potential in In vitro studies. Molecular docking regarding acetylcholinesterase enzyme inhibition revealed that α-copaene has superior action compared to the drug physostigmine. The results of molecular docking for Candida albicans showed that α-copaene and α-humulene interacted in the same binding region as the PepA inhibitor against SAP5. This indicates their action is similar to the aspartic protease inhibitor, in addition to the possibility of a synergistic effect with the drug fluconazole. This is the first study of the biological potential of the essential oil from T. guianensis leaves, thus revealing its high potential for future studies in the scientific community. Therefore, we can infer that the essential oil of T. guianensis is a source of antioxidant, anticholinesterase, and antifungal constituents, with promising therapeutic potential in the management of Alzheimer's disease and Candida infections.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"15 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139783563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Sensitivity Associated with Porphyromonas gingivalis Present in Periodontitis Frameworks: An Integrative Review","authors":"Matéus Simplício Araújo, Antônio Evandro de Sousa Silva, Júlio César Sousa Prado","doi":"10.9734/acri/2024/v24i2633","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2633","url":null,"abstract":"Objectives: The Gram-negative anaerobic bacterium Porphyromonas gingivalis is identified as one of the most important causes of the chronic form of periodontitis. This work aimed to analyze the sensitivity of P. gingivalis to antibiotics and antimicrobial agents. \u0000Study Design: Integrative literature review. \u0000Methodology: Through a careful analysis of clinical trials published in the last 5 years. A bibliographic search was carried out in the PubMed, Scielo and Google Scholar databases. Three keywords were established and verified on the DeCs-Descritores em Ciências da Saúde website for the literary search “Antimicrobial resistance”, “Periodontal biotherapy” and “Porphyromonas gingivalis”. 66 articles were found. Of these, animal studies, studies that did not involve patients diagnosed with periodontitis according to the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, and studies on peri-implantitis were excluded. Studies that used only surgical therapy without association with at least one antibiotic or antimicrobial and duplicate studies were excluded. \u0000Results: This integrative review presents the results of 19 studies. Amoxicillin, Metronidazole and Azithromycin are the most commonly used antibiotics. Photodynamic therapy has demonstrated benefits in reducing inflammation and P. gingivalis counts. It has been demonstrated that P. gingivalis is not sensitive to Lactobacillus brevis and Lactobacillus plantarum-ProlcSan probiotic gel and tablets, as no reductions in its proportion and total count were observed. Similar results were also observed in the study that investigated the effect of administering piperacillin plus Tazobactam gel and doxycycline gel. \u0000Conclusion: Although most of the articles presented report the sensitivity of P. gingivalis to their protocols, microbiological reduction is not always accompanied by clinical benefit, since periodontal disease is multifactorial. Based on these findings, it is concluded that there are several antimicrobial agents capable of promoting the reduction of this key pathogen in periodontitis.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139849942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Sensitivity Associated with Porphyromonas gingivalis Present in Periodontitis Frameworks: An Integrative Review","authors":"Matéus Simplício Araújo, Antônio Evandro de Sousa Silva, Júlio César Sousa Prado","doi":"10.9734/acri/2024/v24i2633","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2633","url":null,"abstract":"Objectives: The Gram-negative anaerobic bacterium Porphyromonas gingivalis is identified as one of the most important causes of the chronic form of periodontitis. This work aimed to analyze the sensitivity of P. gingivalis to antibiotics and antimicrobial agents. \u0000Study Design: Integrative literature review. \u0000Methodology: Through a careful analysis of clinical trials published in the last 5 years. A bibliographic search was carried out in the PubMed, Scielo and Google Scholar databases. Three keywords were established and verified on the DeCs-Descritores em Ciências da Saúde website for the literary search “Antimicrobial resistance”, “Periodontal biotherapy” and “Porphyromonas gingivalis”. 66 articles were found. Of these, animal studies, studies that did not involve patients diagnosed with periodontitis according to the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, and studies on peri-implantitis were excluded. Studies that used only surgical therapy without association with at least one antibiotic or antimicrobial and duplicate studies were excluded. \u0000Results: This integrative review presents the results of 19 studies. Amoxicillin, Metronidazole and Azithromycin are the most commonly used antibiotics. Photodynamic therapy has demonstrated benefits in reducing inflammation and P. gingivalis counts. It has been demonstrated that P. gingivalis is not sensitive to Lactobacillus brevis and Lactobacillus plantarum-ProlcSan probiotic gel and tablets, as no reductions in its proportion and total count were observed. Similar results were also observed in the study that investigated the effect of administering piperacillin plus Tazobactam gel and doxycycline gel. \u0000Conclusion: Although most of the articles presented report the sensitivity of P. gingivalis to their protocols, microbiological reduction is not always accompanied by clinical benefit, since periodontal disease is multifactorial. Based on these findings, it is concluded that there are several antimicrobial agents capable of promoting the reduction of this key pathogen in periodontitis.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139790174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance Evaluation of Power Weeder with Different Blade Mechanism in Intra-row Weeding Operation","authors":"S. M. Khayer, Thaneswer Patel, Britan Rahman, Perves Ahmed","doi":"10.9734/acri/2024/v24i2632","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2632","url":null,"abstract":"Aims: Weeding operation is one of the most laborious and time-consuming operation in agriculture. Weeds basically an unwanted plant which competes with crop for light, moisture, and nutrient along with lowering the overall yield. Mechanical weed control methods are preferred among all weeding methods due to many reasons such as timeliness, safety, drudgery and cost effective. \u0000Study Area and Duration: The experiment was conducted in the farmer’s field of Abhayapuri, Bongaigaon, Assam in the year 2021 to 2023. \u0000Methodology: This study employed a 5.75 hp self-propelled diesel engine with three blade sets—rotary, non-rotary, and a combination of both, designed for weeding in vegetable fields with row spacing up to 75 cm. One-way ANOVA analysis compared group means for statistical significance. \u0000Results: Results showed that the field efficiency (90%), fuel consumption (7.7 l/ha), cost of operation (Rs 1217.7 per ha) and plant damage factor (0.01%) was better for rotary blade than non-rotary and combined blade. Whereas effective field capacity (0.07 ha/h), performance index (155.7) and man-hour/ha (14.3) was better for non-rotary blade and the parameters such as depth (4.4 cm) and weeding efficiency (94.2%) was better for combined blade mechanism. From the one-way ANOVA analysis, it showed that blade mechanism showed significant difference on parameters like weeding efficiency, field efficiency, fuel consumption, effective field capacity, cost of operation, man-h/ha and performance index at p<0.05 and non-significant for depth and plant damage factor at P<0.05. \u0000Conclusion: Study concluded that for intra-row weeding operation, rotary blade along with non-rotary blade was suitable economically whereas combined blade was suitable for weeding performance only besides high cost.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"20 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139805536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance Evaluation of Power Weeder with Different Blade Mechanism in Intra-row Weeding Operation","authors":"S. M. Khayer, Thaneswer Patel, Britan Rahman, Perves Ahmed","doi":"10.9734/acri/2024/v24i2632","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2632","url":null,"abstract":"Aims: Weeding operation is one of the most laborious and time-consuming operation in agriculture. Weeds basically an unwanted plant which competes with crop for light, moisture, and nutrient along with lowering the overall yield. Mechanical weed control methods are preferred among all weeding methods due to many reasons such as timeliness, safety, drudgery and cost effective. \u0000Study Area and Duration: The experiment was conducted in the farmer’s field of Abhayapuri, Bongaigaon, Assam in the year 2021 to 2023. \u0000Methodology: This study employed a 5.75 hp self-propelled diesel engine with three blade sets—rotary, non-rotary, and a combination of both, designed for weeding in vegetable fields with row spacing up to 75 cm. One-way ANOVA analysis compared group means for statistical significance. \u0000Results: Results showed that the field efficiency (90%), fuel consumption (7.7 l/ha), cost of operation (Rs 1217.7 per ha) and plant damage factor (0.01%) was better for rotary blade than non-rotary and combined blade. Whereas effective field capacity (0.07 ha/h), performance index (155.7) and man-hour/ha (14.3) was better for non-rotary blade and the parameters such as depth (4.4 cm) and weeding efficiency (94.2%) was better for combined blade mechanism. From the one-way ANOVA analysis, it showed that blade mechanism showed significant difference on parameters like weeding efficiency, field efficiency, fuel consumption, effective field capacity, cost of operation, man-h/ha and performance index at p<0.05 and non-significant for depth and plant damage factor at P<0.05. \u0000Conclusion: Study concluded that for intra-row weeding operation, rotary blade along with non-rotary blade was suitable economically whereas combined blade was suitable for weeding performance only besides high cost.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"19 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139865608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiological Risk Assessment of Soil Using RESRAD-OFFSITE Code in Communities around Indorama Fertilizer Company Eleme, Port-Harcourt, Rivers State, Nigeria","authors":"Evelyn V. Furo, I.A. Hart, C. Ononugbo","doi":"10.9734/acri/2024/v24i2630","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2630","url":null,"abstract":"Anthropogenic activities around a fertilizer company can cause elevation in the concentration of naturally-occurring radioactive materials (NORMs) within surrounding soils, as a result of effluent discharge or heaping of rocks used as raw materials. The aim of this study was to evaluate the human risk associated with exposure to NORMs in soils from communities around Indorama Fertilizer Company Eleme, Port-Harcourt, Rivers State, Nigeria. A sodium-iodide doped with thallium [NaI(TI)] detector was used to measure activity concentrations of these NORMs in 22 soil samples within the study area. The residual radioactivity (RESRAD) offsite modeling program(version 4.0) was then used to estimate the radiation doses and the cancer morbidity risk of uranium-238 (238U), thorium-232 (232Th) and potassium-40 (40K) for hypothetical resident farmer scenario. According to the RESRAD prediction, the maximum total effective dose equivalent (TEDE) during 100 years was found to be 2.82 x 10-5 mSvy-1 at year 12, while the maximum total excess cancer morbidity risk for all the pathways was 3.52E-08 at year 6. Therefore, results obtained from the RESRAD-OFFSITE code in this study has shown that the health risk from effluent discharge within the study area is within acceptable levels according to international standards.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139891974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Superior Cross Combinations and Identification of Better Parental Stocks from Early Clonal Trials in Sugarcane","authors":"Sreenivasa V., Amaresh, Aswini Nunavath, Dhanya V. G., Abhishek G. J., Mahadevaiah C., A. S. Pazhany, M. Alagupalamuthirsolai, Arun Kumar, A. Durai, Ravinder Kumar, Meena Minturam, Appunu C., Hemaprabha G.","doi":"10.9734/acri/2024/v24i2631","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2631","url":null,"abstract":"Sugarcane is a clonally propagated crop and genetic improvement involves crossing of diverse species of Saccharum clones. Identification of desirable cross combination is one of the essential steps in the development of superior varieties. This study was conducted with an objective of identification of best cross combination based on their ability to produce superior clones by contributing desirable traits and suitability of a parental stock as “FEMALES” or “MALES” based on their ability to transmit positive genes to progeny. Sixteen biparental crosses with minimum of 20 progenies were screened for NMC (≥10) and HR Brix (≥20 units) in first clonal selection. The significance of parental stocks performance in cross combination was tested using “t‟ test assuming unequal variance. Progenies obtained from Co 06015, Co 0241 and Co 8347 recorded 20.99%, 20.82% and 20.81% of HR Brix, while Co 0209, Co 06015 and Co 94008 recorded 14.23, 12.76 and 11.88 of mean NMC when they used as male in crossing. Clones derived from Co 99006, Co 0403 and Co 06002 showed 20.93%, 20.82% and 20.81% of HR Brix, whereas Co 07010, Co 99006 and 2007-285 recorded 13.68, 12.21 and 11.40 mean NMC when they were used as female in crossing. Crosses viz., Co 99006 x Co 06015, Co 0403 x Co 0241, 2007-285 x Co 0209 and Co 94005 x Co 86011 has contributed 63%, 32%, 30% and 28% desirable selections respectively. The clones Co 06015 and Co 99006 are proven male and female can be used abundantly in crossing for the development of superior clones. The clones Co 8347, Co 0241, Co 0209 and Co 94008 are best males, whereas Co 0403, Co 06002, Co 07010 and 2007-285 are best females need to be crossed extensively for the development of superior varieties combining quality and cane yield traits.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiological Risk Assessment of Soil Using RESRAD-OFFSITE Code in Communities around Indorama Fertilizer Company Eleme, Port-Harcourt, Rivers State, Nigeria","authors":"Evelyn V. Furo, I.A. Hart, C. Ononugbo","doi":"10.9734/acri/2024/v24i2630","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2630","url":null,"abstract":"Anthropogenic activities around a fertilizer company can cause elevation in the concentration of naturally-occurring radioactive materials (NORMs) within surrounding soils, as a result of effluent discharge or heaping of rocks used as raw materials. The aim of this study was to evaluate the human risk associated with exposure to NORMs in soils from communities around Indorama Fertilizer Company Eleme, Port-Harcourt, Rivers State, Nigeria. A sodium-iodide doped with thallium [NaI(TI)] detector was used to measure activity concentrations of these NORMs in 22 soil samples within the study area. The residual radioactivity (RESRAD) offsite modeling program(version 4.0) was then used to estimate the radiation doses and the cancer morbidity risk of uranium-238 (238U), thorium-232 (232Th) and potassium-40 (40K) for hypothetical resident farmer scenario. According to the RESRAD prediction, the maximum total effective dose equivalent (TEDE) during 100 years was found to be 2.82 x 10-5 mSvy-1 at year 12, while the maximum total excess cancer morbidity risk for all the pathways was 3.52E-08 at year 6. Therefore, results obtained from the RESRAD-OFFSITE code in this study has shown that the health risk from effluent discharge within the study area is within acceptable levels according to international standards.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"312 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139832133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Superior Cross Combinations and Identification of Better Parental Stocks from Early Clonal Trials in Sugarcane","authors":"Sreenivasa V., Amaresh, Aswini Nunavath, Dhanya V. G., Abhishek G. J., Mahadevaiah C., A. S. Pazhany, M. Alagupalamuthirsolai, Arun Kumar, A. Durai, Ravinder Kumar, Meena Minturam, Appunu C., Hemaprabha G.","doi":"10.9734/acri/2024/v24i2631","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2631","url":null,"abstract":"Sugarcane is a clonally propagated crop and genetic improvement involves crossing of diverse species of Saccharum clones. Identification of desirable cross combination is one of the essential steps in the development of superior varieties. This study was conducted with an objective of identification of best cross combination based on their ability to produce superior clones by contributing desirable traits and suitability of a parental stock as “FEMALES” or “MALES” based on their ability to transmit positive genes to progeny. Sixteen biparental crosses with minimum of 20 progenies were screened for NMC (≥10) and HR Brix (≥20 units) in first clonal selection. The significance of parental stocks performance in cross combination was tested using “t‟ test assuming unequal variance. Progenies obtained from Co 06015, Co 0241 and Co 8347 recorded 20.99%, 20.82% and 20.81% of HR Brix, while Co 0209, Co 06015 and Co 94008 recorded 14.23, 12.76 and 11.88 of mean NMC when they used as male in crossing. Clones derived from Co 99006, Co 0403 and Co 06002 showed 20.93%, 20.82% and 20.81% of HR Brix, whereas Co 07010, Co 99006 and 2007-285 recorded 13.68, 12.21 and 11.40 mean NMC when they were used as female in crossing. Crosses viz., Co 99006 x Co 06015, Co 0403 x Co 0241, 2007-285 x Co 0209 and Co 94005 x Co 86011 has contributed 63%, 32%, 30% and 28% desirable selections respectively. The clones Co 06015 and Co 99006 are proven male and female can be used abundantly in crossing for the development of superior clones. The clones Co 8347, Co 0241, Co 0209 and Co 94008 are best males, whereas Co 0403, Co 06002, Co 07010 and 2007-285 are best females need to be crossed extensively for the development of superior varieties combining quality and cane yield traits.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139815607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific Nursing Production about Alzheimer's Disease: A Bibliometric Study","authors":"Dayara de Nazaré Rosa de Carvalho, Thanaira Aicha Fernandes Maciel, Bárbara Leticia Corrêa Gomes, Amanda Ourqiues de Gouveia, Dandara de Fátima Ribeiro Bendelaque, Kelly de Cássia Peixoto de Oliveira Silveira, V. Aguiar, Fabiana de Souza Orlandi, Camila Almeida Bonfim, Ivonete Vieira Pereira Peixoto","doi":"10.9734/acri/2024/v24i2629","DOIUrl":"https://doi.org/10.9734/acri/2024/v24i2629","url":null,"abstract":"Aims: to analyze and map the international scientific production of Nursing on Alzheimer's Disease, in the historical series from January 2016 to November 2021. \u0000Methodology: This is a study of a basic nature, with a mixed approach and under the light of procedures methodological, configures itself as research of the Bibliometric type. Data collection took place in July 2021 through institutional online access to the CAPES Journal Portal, in the Scopus (Elsevier) database, using the combination of the following MESHs: \"Alzheimer's disease\", \"Elderly\", \"Very Old\" and “Nursing”, all mediated by the Boolean operators “AND” and/or “OR”. The final sampling resulted in 189 publications. \u0000Results: n=189 publications were identified, distributed in n=66 journals, divided into 30 countries. It was evidenced that the year 2016 has the highest number of publications with n=44 (23.28%), followed by the year 2017 with n=42 (22.22%) articles and 2018 with n=38 (20.11) %) articles, these being the years with the highest number of publications. From the analysis of the included studies, it was observed that the publications that made up this Bibliometric review addressed 4 large distinct thematic groups: 1) Difficulties encountered by family caregivers with elderly people with Alzheimer's disease; 2) Nursing in Home Care for the Elderly with Alzheimer's Disease in Palliative Care; 3) Behaviors Observed in Elderly People with Severe Dementia and 4) Quality of Life in Elderly People with Cognitive Disabilities. \u0000Conclusion: Despite the few publications in the database, it is observed that the publications are at a high level of quality when we look at the evaluation metrics of the selected studies. It can be seen that the main research centers on the subject are in countries such as France, Japan, the United Kingdom and the Netherlands. Furthermore, the study demonstrated the various gaps that need to be addressed and deepened on the subject that require scientific investigation.","PeriodicalId":505151,"journal":{"name":"Archives of Current Research International","volume":"39 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140477025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}