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Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity. GADD45B在IgA肾病患儿肾组织中的表达及其与肾小球系膜肥大的关系。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-08-03 DOI: 10.1080/15513815.2023.2239904
Chong Li, Ailing Wei, Yuanhan Qin
{"title":"Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity.","authors":"Chong Li,&nbsp;Ailing Wei,&nbsp;Yuanhan Qin","doi":"10.1080/15513815.2023.2239904","DOIUrl":"10.1080/15513815.2023.2239904","url":null,"abstract":"<p><p><b>Background:</b> We correlated the expression of growth arrest and DNA damage-inducible protein beta (GADD45B) in renal tissue with IgA nephropathy (IgAN) with clinical characteristics and mesangial hypercellularity. <b>Materials and methods:</b> Biopsies from IgAN children were divided into M0 and M1 groups based on the Oxford classification, and biopsies with minimal change disease (MCD) were selected as controls. The mesangial cell proliferation area was evaluated on PAS-stained tissues, and the relative level of GADD45B in renal tissue was assessed by immunohistochemical staining (IHC). <b>Results:</b> Compared with the MCD group, levels of GADD45B in the M0 and M1 groups were significantly higher (<i>p</i> < 0.05). Levels of GADD45B positively correlated with mesangial cell proliferation, proteinuria, and total cholesterol, negatively correlated with Alb levels. <b>Conclusions:</b> It is suggested that high expression of GADD45B may play a regulatory role in mesangial hypercellularity.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"785-795"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10294250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SIX1 as a Novel Immunohistochemical Marker in the Differential Diagnosis of Rhabdomyosarcoma. SIX1作为一种新的免疫组织化学标记物在横纹肌肉瘤鉴别诊断中的应用。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-05-24 DOI: 10.1080/15513815.2023.2214806
Daniel Ehinger, Hanna Frostberg, Sofia Larsson, David Gisselsson
{"title":"SIX1 as a Novel Immunohistochemical Marker in the Differential Diagnosis of Rhabdomyosarcoma.","authors":"Daniel Ehinger,&nbsp;Hanna Frostberg,&nbsp;Sofia Larsson,&nbsp;David Gisselsson","doi":"10.1080/15513815.2023.2214806","DOIUrl":"10.1080/15513815.2023.2214806","url":null,"abstract":"<p><p><b>Background:</b> Differential diagnosis of rhabdomyosarcoma (RMS) is challenging. Sineoculis homeobox homolog 1 (SIX1) is an oncogene involved in skeletal muscle differentiation. We compared protein expression patterns of SIX1 in RMS and its most common differential diagnoses. <b>Methods:</b> SIX1 immunohistochemistry in 36 RMS and in 33 tumors from seven differential diagnostic subtypes were evaluated. The fraction of SIX1 positive tumor cells was scored by three independent observers. <b>Results:</b> A majority (75%) of the evaluated RMS expressed SIX1 in at least 50% of tumor cells and all except one RMS had more than 25% positive tumor cells. Neuroblastoma had less than 1% SIX1 positive tumor cells. Gonadoblastoma, malignant rhabdoid tumor, and Ewing sarcoma had 10% or less positive tumor cells. Pleuropulmonary blastoma exhibited 26-50% positive tumor cells and synovial sarcoma >50% positive cells. <b>Conclusion:</b> SIX1 immunohistochemistry is positive in most RMS, and occasionally in some tumors within the differential diagnoses of RMS.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"723-734"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10301120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurogenic Monodermal Teratoma in the Scapula of a Child: A Case Report. 儿童肩胛神经源性单真皮畸胎瘤：一例报告。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-09-01 DOI: 10.1080/15513815.2023.2224443
Xianping Jiang, Huan Zhang, Xifeng Du, Cailei Zhao, Qiuling Miao, Jianming Song
{"title":"Neurogenic Monodermal Teratoma in the Scapula of a Child: A Case Report.","authors":"Xianping Jiang,&nbsp;Huan Zhang,&nbsp;Xifeng Du,&nbsp;Cailei Zhao,&nbsp;Qiuling Miao,&nbsp;Jianming Song","doi":"10.1080/15513815.2023.2224443","DOIUrl":"10.1080/15513815.2023.2224443","url":null,"abstract":"<p><p><b>Background:</b> Neurogenic monodermal teratomas (NMTs) have been reported in the ovaries but not from bone. <b>Case Report</b>: A 6-year-old girl had an incidentally discovered lesion in the right scapula. Upon removal, it was an NMT with predominant choroid plexus. The disease had not progressed for 31 months. <b>Conclusion:</b> Neurogenic monodermal teratomas can also occur in bone.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"815-819"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10304561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Hypertension and Early-Onset Neonatal Neutropenia. 母体高血压与早期发病的新生儿中性粒细胞减少症。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-06-05 DOI: 10.1080/15513815.2023.2220406
Peter Joslyn, Evrim Oral, Anne Martin, Jeffrey Surcouf, Brian Barkemeyer
{"title":"Maternal Hypertension and Early-Onset Neonatal Neutropenia.","authors":"Peter Joslyn,&nbsp;Evrim Oral,&nbsp;Anne Martin,&nbsp;Jeffrey Surcouf,&nbsp;Brian Barkemeyer","doi":"10.1080/15513815.2023.2220406","DOIUrl":"10.1080/15513815.2023.2220406","url":null,"abstract":"<p><p><b>Objective:</b> Maternal hypertension is considered a risk factor for early neonatal neutropenia. We sought to explore this relationship. <b>Study Design:</b> This retrospective cohort study compared initial neutrophil counts in infants born to mothers with preeclampsia with severe features (PSF) and infants born to normotensive mothers using Negative Binomial Regression (NBR) and logistic regression models. <b>Results:</b> Maternal hypertension negatively affected the early neonatal neutrophil count (adjusted NRB coefficient 0.4 [0.2, 0.6], <i>p</i> < 0.0001) but did not increase the risk of neutropenia (OR 2.07 [0.97, 4.41], <i>p</i> = 0.06). The initial neutrophil count and neutropenia risk were not different between PSF subgroups. Gestational age had the greatest impact on neutropenia risk (OR 0.72 [0.64, 0.81], <i>p</i> < 0.0001). Almost all neutropenia resolved within 48 h. <b>Conclusion:</b> Maternal hypertension negatively affects the early neonatal neutrophil count while not increasing the risk of neonatal neutropenia.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"735-745"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10645891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Placental Pathology and Its Importance in Preterm Infants. 胎盘病理学及其在早产儿中的重要性。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-06-21 DOI: 10.1080/15513815.2023.2223297
Duygu Tugrul Ersak, Hakkı Şerbetçi, Bergen Laleli Koç, Özgür Kara, Şeyma Bütün Türk, Gülsüm Kadıoğlu Şimşek, Fuat Emre Canpolat, Özlem Moraloğlu Tekin, Dilek Şahin
{"title":"Placental Pathology and Its Importance in Preterm Infants.","authors":"Duygu Tugrul Ersak,&nbsp;Hakkı Şerbetçi,&nbsp;Bergen Laleli Koç,&nbsp;Özgür Kara,&nbsp;Şeyma Bütün Türk,&nbsp;Gülsüm Kadıoğlu Şimşek,&nbsp;Fuat Emre Canpolat,&nbsp;Özlem Moraloğlu Tekin,&nbsp;Dilek Şahin","doi":"10.1080/15513815.2023.2223297","DOIUrl":"10.1080/15513815.2023.2223297","url":null,"abstract":"<p><strong>Objective: </strong>We evaluated what placental pathologies were associated with adverse preterm births.</p><p><strong>Materials and methods: </strong>Placental findings, classified according to the Amsterdam criteria, were correlated with infant outcomes. The fetal vascular lesions, inflammatory responses other than histological chorioamnionitis (HCA), and placentas with combined maternal vascular malperfusion (MVM) and HCA were excluded.</p><p><strong>Results: </strong>A total of 772 placentas were evaluated. MVM was present in 394 placentas, HCA in 378. Early neonatal sepsis, retinopathy of prematurity, necrotizing enterocolitis, and neonatal death occurred more often in the MVM-only group than HCA-only group. The frequency of bronchopulmonary dysplasia (BPD) was 38.6% in the HCA-only group, and it was 20.3% in the MVM-only group (<i>p</i> < 0.001). HCA was the most important independent risk factor for BPD (OR 3.877, 95% CI 2.831-5.312).</p><p><strong>Conclusion: </strong>Inflammation in the placenta influences fetal and neonatal outcomes. HCA is an independent risk factor for BPD.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"746-752"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10299414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Erythromycin Attenuates Hyperoxia Induced Lung Injury by Enhancing GSH Expression and Inhibiting Expression of Inflammatory Cytokines. 红霉素通过增强GSH的表达和抑制炎症细胞因子的表达来减轻高氧诱导的肺损伤。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-06-21 DOI: 10.1080/15513815.2023.2223722
Xiaoyun Chu, Xiaoyue Zhang, Bowen Weng, Xiaotong Yin, Cheng Cai
{"title":"Erythromycin Attenuates Hyperoxia Induced Lung Injury by Enhancing GSH Expression and Inhibiting Expression of Inflammatory Cytokines.","authors":"Xiaoyun Chu,&nbsp;Xiaoyue Zhang,&nbsp;Bowen Weng,&nbsp;Xiaotong Yin,&nbsp;Cheng Cai","doi":"10.1080/15513815.2023.2223722","DOIUrl":"10.1080/15513815.2023.2223722","url":null,"abstract":"<p><p><b>Introduction:</b> Oxidative stress and inflammation have proven to be key factors contributing to the occurrence of BPD. Erythromycin has been shown to be effective in treating the redox imbalance seen in many non-bacterial infectious chronic inflammatory diseases. <b>Methods:</b> Ninety-six premature rats were randomly divided into air + saline chloride group, air + erythromycin group, hyperoxia + saline chloride group and hyperoxia + erythromycin group. Lung tissue specimens were collected from 8 premature rats in each group on days 1, 7 and 14, respectively. <b>Results:</b> Pulmonary pathological changes in premature rats after hyperoxia exposure were similar to those of BPD. Hyperoxia exposure induced high expression of GSH, TNF-α, and IL-1β. Erythromycin intervention caused a further increase in GSH expression and a decrease in TNF-α and IL-1β expression. <b>Conclusion:</b> GSH, TNF-α and IL-1β are all involved in the development of BPD. Erythromycin may alleviate BPD by enhancing the expression of GSH and inhibiting the release of inflammatory mediators.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"766-774"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10299418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Antioxidant Marker in Cord Blood of Fetuses with Late Fetal Growth Restriction: Humanin. 胎儿生长迟缓胎儿脐血中一种新的抗氧化标记物：人源蛋白。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-10-01 Epub Date: 2023-06-27 DOI: 10.1080/15513815.2023.2229432
Caner Kose, Busra Korpe, Kadriye Yakut Yucel, Ozgur Arat, Mevlut Bucak, Yaprak Engin Ustun
{"title":"A New Antioxidant Marker in Cord Blood of Fetuses with Late Fetal Growth Restriction: Humanin.","authors":"Caner Kose,&nbsp;Busra Korpe,&nbsp;Kadriye Yakut Yucel,&nbsp;Ozgur Arat,&nbsp;Mevlut Bucak,&nbsp;Yaprak Engin Ustun","doi":"10.1080/15513815.2023.2229432","DOIUrl":"10.1080/15513815.2023.2229432","url":null,"abstract":"<p><p><b>Purpose:</b> This study investigated the Humanin levels in the umbilical cord blood of fetuses with late fetal growth restriction (FGR) and -evaluated their association with perinatal outcomes. <b>Materials and Methods:</b> A total of 95 single pregnancies between 32-41 wk (45 with late FGR and 50 controls) were included. Doppler parameters, birth weight and the need for neonatal intensive care unit admission (NICU) were assessed. Correlations between Humanin levels and these parameters were analyzed. <b>Results:</b> Higher Humanin levels were found in fetuses with late FGR compared to the control group (<i>p</i> < 0.05). No significant correlation was observed between Humanin levels and Doppler parameters. Elevated Humanin levels were associated with an increased need for NICU (<i>p</i> < 0.05). <b>Conclusions:</b> The statistically higher levels of Humanin in fetuses with late FGR may suggest the potential of Humanin as an indicator of late FGR. Further research is needed to explore the clinical utility of Humanin.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 5","pages":"775-784"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10647404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phyllodes Tumor of the Bladder in a 2-Year-Old Boy - An Exceptional Finding. 一名2岁男孩的膀胱叶状肿瘤——一项特殊发现。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-08-01 Epub Date: 2023-03-30 DOI: 10.1080/15513815.2023.2193274
Taycir Cheikhrouhou, Mahdi Ben Dhaou, Slim Charfi, Manar Hbaieb, Mohamed Zouari, Hayet Zitouni, Tahya Sellami Boudawara, Riadh Mhiri
{"title":"Phyllodes Tumor of the Bladder in a 2-Year-Old Boy - An Exceptional Finding.","authors":"Taycir Cheikhrouhou,&nbsp;Mahdi Ben Dhaou,&nbsp;Slim Charfi,&nbsp;Manar Hbaieb,&nbsp;Mohamed Zouari,&nbsp;Hayet Zitouni,&nbsp;Tahya Sellami Boudawara,&nbsp;Riadh Mhiri","doi":"10.1080/15513815.2023.2193274","DOIUrl":"10.1080/15513815.2023.2193274","url":null,"abstract":"<p><p><b>Background:</b> Breast phyllodes tumor has a distinct histologic appearance. There are no pediatric phyllodes tumors of the bladder in English literature reported. <b>Case report:</b> A 2-year-old boy presented with a urinary infection and obstructive urinary symptoms. A 3-cm slow-growing bladder mass revealed by repeated transabdominal ultrasonography was initially considered a ureterocele. Cystoscopic and laparoscopic exploration using pneumovesicum confirmed the diagnosis of a bladder neck tumor. Histologically, the features were of a benign phyllodes tumor, morphologically similar to those seen in breast tissue. The patient received no further treatment and showed no recurrence or metastasis. <b>Conclusion:</b> Phyllodes tumor can cause a pediatric bladder tumor.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 4","pages":"699-705"},"PeriodicalIF":1.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9832000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Vitamin-D Deficiency and Protein Oxidation Among Obese Children. 肥胖儿童维生素d缺乏与蛋白质氧化的关系
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-08-01 DOI: 10.1080/15513815.2023.2183026
Ilknur Surucu Kara, Cuma Mertoglu, Gülsah Siranli, Yusuf Kemal Arslan, Gamze Gok, Ozcan Erel
{"title":"The Relationship Between Vitamin-D Deficiency and Protein Oxidation Among Obese Children.","authors":"Ilknur Surucu Kara,&nbsp;Cuma Mertoglu,&nbsp;Gülsah Siranli,&nbsp;Yusuf Kemal Arslan,&nbsp;Gamze Gok,&nbsp;Ozcan Erel","doi":"10.1080/15513815.2023.2183026","DOIUrl":"https://doi.org/10.1080/15513815.2023.2183026","url":null,"abstract":"<p><p><b>Aim:</b> The aim of the study is to examine the relationship between obesity, Vitamin-D deficiency, and protein oxidation. <b>Methods:</b> Thiol-disulfide homeostasis, Vitamin-D, ischemia modified albumin, insulin, and lipid levels were compared among obese, pre-obese and normal-weight healthy children. <b>Results:</b> A total of 136 children (69 boys and 67 girls) were included in the study. The vitamin-D levels of obese children were lower than those of pre-obese and normal weight (p < 0.05). In the normal weight group, total thiol and native thiol were lower in the pubertal period than in adolescence; were higher in those with sufficient Vitamin-D level than those with insufficient and deficient Vitamin-D (p < 0.05). Vitamin-D level was lower in pre-obese girls than boys (p < 0.05). Those with high triglycerides had high disulfide/total thiol, disulfide, and disulfide/native thiol and low native thiol/total thiol (p < 0.05). <b>Conclusion:</b> Thiol-disulfide homeostasis is negatively affected by low vitamin D levels, pubertal period and high triglyceride levels.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 4","pages":"599-613"},"PeriodicalIF":1.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9852536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skene's Gland Cyst - Case Report of a 2-Year-Old Girl. Skene腺囊肿——一例2岁女孩的报告。
IF 1.1 4区 医学
Fetal and Pediatric Pathology Pub Date : 2023-08-01 Epub Date: 2023-03-07 DOI: 10.1080/15513815.2023.2186694
Patrícia Sousa, Susana Correia-de-Oliveira, Marcos Guimarães, Ângela Dias, João Moreira-Pinto
{"title":"Skene's Gland Cyst - Case Report of a 2-Year-Old Girl.","authors":"Patrícia Sousa,&nbsp;Susana Correia-de-Oliveira,&nbsp;Marcos Guimarães,&nbsp;Ângela Dias,&nbsp;João Moreira-Pinto","doi":"10.1080/15513815.2023.2186694","DOIUrl":"10.1080/15513815.2023.2186694","url":null,"abstract":"<p><strong>Background: </strong>Skene's glands are the two largest paraurethral glands and the female homologue to the prostate glands. When their ducts become obstructed, cysts may be formed. This usually occurs in adult women. Most cases reported in pediatrics are neonatal, with a single report in a prepubertal girl.</p><p><strong>Case report: </strong>We present a 25-month-old girl with a 7 mm nontender, solid, oval, pink-orange paraurethral mass, with no change over a five-month period. Histopathology revealed the cyst to be lined with transitional epithelium consistent with a Skene's gland cyst. The child did well with no sequalae.</p><p><strong>Conclusion: </strong>We describe a Skene's gland cyst found in a prepubertal child.</p>","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":"42 4","pages":"685-689"},"PeriodicalIF":1.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9844179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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