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Nanotechnologies for the Life Sciences, Vol. 3: Nanosystem Characterization Tools in the Life Sciences (Kumar, C.S.S.R.; 2006) [Book review] 纳米技术的生命科学，卷3:纳米系统表征工具在生命科学(库马尔，C.S.S.R.;2006)[书评]
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-11-01 DOI: 10.1109/MEMB.2009.934911
H. Liu
{"title":"Nanotechnologies for the Life Sciences, Vol. 3: Nanosystem Characterization Tools in the Life Sciences (Kumar, C.S.S.R.; 2006) [Book review]","authors":"H. Liu","doi":"10.1109/MEMB.2009.934911","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934911","url":null,"abstract":"This book presented several important characterization tools that are currently used in life science and in the process of development of biological applications. This text is written by more than 20 authors, with a wide range of expertise in characterization techniques. The authors assume that the readers are familiar with basic concepts and terminologies of engineering and biology. Each characterization tool is organized into a chapter, and the chapters are written at a level that this reviewer would suggest as a reference text for graduate students, researchers, and scientists who are interested in characterization techniques for the life science. The book covers very broad characterization tools and would be too intense for most undergraduates.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934911","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62475749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Concealed conduction effects in the atrium. 心房隐蔽传导效应。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-11-01 DOI: 10.1109/MEMB.2009.934628
Jan J Zebrowski, Pawel Kuklik, Teodor Buchner, Rafał Baranowski
{"title":"Concealed conduction effects in the atrium.","authors":"Jan J Zebrowski,&nbsp;Pawel Kuklik,&nbsp;Teodor Buchner,&nbsp;Rafał Baranowski","doi":"10.1109/MEMB.2009.934628","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934628","url":null,"abstract":"<p><p>A one-dimensional (1-D) model of the atrium together with the sinoatrial (SA) and atrioventricular (AV) nodes is presented in this article. The two nodes are each modeled by 15-element, diffusively coupled, modified van der Pol oscillator chains, while the atrium tissue is represented by a 90-element chain of diffusively coupled FitzHugh-Nagumo (FHN) equations. The modified van der Pol oscillators are able to reproduce physiologically important properties, such as the refraction period, phase-sensitivity properties, and modes of change of the action potential frequency. The activity of both branches of the autonomous nervous system may be introduced into the model in a simplified way. The model enables the study of the effect of the magnitude of the action potential conduction rate in the nodes on interspike intervals (ISIs; equivalent of RR intervals) and explains the occurrence of RR-interval alternans in certain patients. The effect of breathing modulation of heart rate and of a single deep breath can also be modeled. Finally, concealed conduction effects in the atrium are studied, yielding results comparable with recorded heart rate variability data.</p>","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934628","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28509628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Autonomic neural control of cerebral hemodynamics. 自主神经控制脑血流动力学。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-11-01 DOI: 10.1109/MEMB.2009.934908
Georgios D Mitsis, Rong Zhang, Benjamin D Levine, Efthalia Tzanalaridou, Demosthenes G Katritsis, Vasilis Z Marmarelis
{"title":"Autonomic neural control of cerebral hemodynamics.","authors":"Georgios D Mitsis,&nbsp;Rong Zhang,&nbsp;Benjamin D Levine,&nbsp;Efthalia Tzanalaridou,&nbsp;Demosthenes G Katritsis,&nbsp;Vasilis Z Marmarelis","doi":"10.1109/MEMB.2009.934908","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934908","url":null,"abstract":"<p><p>Despite the rich innervation of the cerebral vasculature by both sympathetic and parasympathetic nerves, the role of autonomic control in cerebral circulation and, particularly, cerebral hemodynamics is not entirely clear. Previous animal studies have reported inconsistent results regarding the effects of electrical stimulation or denervation on cerebral blood flow (CBF), cerebral pressure-flow relationship, and cerebral vessel response to metabolic stimuli. Moreover, with the advance of transcranial Doppler ultrasound (TCD), which yields accurate measurements of CBF velocity (CBFV) with high time resolution, it has been found that in humans CBFV in the middle cerebral artery decreased substantially during lower body negative pressure (LBNP) and head-up tilt in the absence of systemic hypotension, which suggests the presence of cerebral vasoconstriction associated with augmented sympathetic nerve activity during orthostatic stress. These observations were based on assessing static measures of cerebral circulation, i.e., mean values of artevial blood pressure (ABP) and CBF with a low time resolution.</p>","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934908","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28509545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Complexity of the short-term heart-rate variability. 短期心率变异性的复杂性。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-11-01 DOI: 10.1109/MEMB.2009.934621
Jose F Valencia, Montserrat Vallverdú, Rico Schroeder, Andreas Voss, Rafael Vázquez, Antonio Bayés de Luna, Pere Caminal
{"title":"Complexity of the short-term heart-rate variability.","authors":"Jose F Valencia,&nbsp;Montserrat Vallverdú,&nbsp;Rico Schroeder,&nbsp;Andreas Voss,&nbsp;Rafael Vázquez,&nbsp;Antonio Bayés de Luna,&nbsp;Pere Caminal","doi":"10.1109/MEMB.2009.934621","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934621","url":null,"abstract":"<p><p>This work has proposed a methodology based on the concept of entropy rates to study the complexity of the short-term heart-rate variability (HRV) for improving risk stratification to predict sudden cardiac death (SCD) of patients with established ischemic-dilated cardiomyopathy (IDC). The short-term HRV was analyzed during daytime and nighttime by means of RR series. An entropy rate was calculated on the RR series, previously transformed to symbol sequences by means of an alphabet. A statistical analysis permitted to stratify high- and low-risk patients of suffering SCD, with a specificity (SP) of 95% and sensitivity (SE) of 83.3%.</p>","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28509546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
An Introductory Text to Bioengineering (Advanced Series in Biomechanics, Vol. 4) (Chien, S. et al; 2008) [Book reviews] 生物工程导论(生物力学高级系列，第4卷)(Chien, S. et al;2008)[书评]
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-22 DOI: 10.1109/MEMB.2009.934241
H. Sung
{"title":"An Introductory Text to Bioengineering (Advanced Series in Biomechanics, Vol. 4) (Chien, S. et al; 2008) [Book reviews]","authors":"H. Sung","doi":"10.1109/MEMB.2009.934241","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934241","url":null,"abstract":"This textbook provides a very comprehensive overview of the issues that bioengineers deal with, such as biomechanics, tissue engineering, nanotechnology, and systems biology.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62475598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Attorneys' fees for the winner [Patents] 胜诉方的律师费[专利]
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-22 DOI: 10.1109/MEMB.2009.934251
M. Klee
{"title":"Attorneys' fees for the winner [Patents]","authors":"M. Klee","doi":"10.1109/MEMB.2009.934251","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934251","url":null,"abstract":"In the United States, the normal rule is that each party to a lawsuit pays its own attorneys' fees. However, some statutes, including the Copyright Act, give the trial judge the authority to make the loser pay some or all of the winner's attorneys' fees when the loser, in one way or another, has acted badly. The question then becomes what constitutes sufficiently bad behavior so as to justify an award of attorneys' fees. That was the question before the court in the recent case of Asset Marketing Systems (AMS) v. Gagnon.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934251","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62475669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Normal versus pathological voice signals. 正常与病理语音信号。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-01 DOI: 10.1109/MEMB.2009.934248
Everthon Fonseca, Jose Pereira
{"title":"Normal versus pathological voice signals.","authors":"Everthon Fonseca,&nbsp;Jose Pereira","doi":"10.1109/MEMB.2009.934248","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934248","url":null,"abstract":"In this work, a method to analyze the time-frequency characteristics to distinguish pathological voices from patients with Reinke's edema and nodules in vocal folds was developed. Daubechies discrete wavelet transform (DWT) components of approximation and detail in convenient scales of frequency for different voice signals were used to analyze the time-frequency signal characteristics. In this work, 71 voice signals were used from subjects of different ages, both male and female: 30 with no pathology in vocal folds, 25 from patients with nodules in vocal folds, and 16 from patients with Reinke's edema. Least squares support-vector machines (LS- SVM) classifier leads to more than 90% of classification accuracy between normal voices and voices from patients with nodules in vocal folds, more than 85% between normal voices and voices from patients with Reinke's edema, and more than 80% between the two different pathological voice signals.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934248","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40031711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Don't play it again, Sam. 别再弹了，萨姆。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-01 DOI: 10.1109/memb.2009.934237
Michael R Neuman
{"title":"Don't play it again, Sam.","authors":"Michael R Neuman","doi":"10.1109/memb.2009.934237","DOIUrl":"https://doi.org/10.1109/memb.2009.934237","url":null,"abstract":"","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/memb.2009.934237","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40035679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pressure-detection algorithms. 压力检测算法。
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-01 DOI: 10.1109/MEMB.2009.934246
J C Perfetto, A G Ruiz, R O Sirne, C E D'Attellis
{"title":"Pressure-detection algorithms.","authors":"J C Perfetto,&nbsp;A G Ruiz,&nbsp;R O Sirne,&nbsp;C E D'Attellis","doi":"10.1109/MEMB.2009.934246","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934246","url":null,"abstract":"Our approach is based on identifying specific characteristics of the arterial blood pressure (ABP) signal. During the development of the algorithm, we examined the signals and tried to extract the features that signals always share with other signals of the same type. These features permit acceptance of a portion of the signal as being part of arterial pressure or reject it as being an artifact. The algorithm first detects the occurrence of the systolic point and, thereafter, the diastolic point. The method we present here is designed to be used in adaptation mechanisms of the cardiovascular system assessment.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934246","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40031708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Signal from noise? 来自噪音的信号?
IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-09-01 DOI: 10.1109/MEMB.2009.934250
Steven Kern, Dov Jaron
{"title":"Signal from noise?","authors":"Steven Kern,&nbsp;Dov Jaron","doi":"10.1109/MEMB.2009.934250","DOIUrl":"https://doi.org/10.1109/MEMB.2009.934250","url":null,"abstract":"In this article, some of the history of rapidly spreading infectious disease pandemics were reviewed as well as the individual technologies currently under development that were presented at the IFMBE meeting. A summary of current strategies to integrate these independent solutions and strategies for future development was presented . Ongoing efforts to address the challenges of detecting signals, developing methods for processing information, and establishing integrated frameworks for effective dissemination of information to manage and combat a global pandemic were also presented.","PeriodicalId":50391,"journal":{"name":"IEEE Engineering in Medicine and Biology Magazine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MEMB.2009.934250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40031714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 32
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