Bioscientia Medicina : Journal of Biomedicine and Translational Research最新文献_第5页

Effect of Diagnosis, Complications, and Nutrition for Using Nasogastric Tube to Body Weight of Child Patients with Feeding Difficulty at Dr. M. Djamil General Hospital, Padang, Indonesia 印度尼西亚巴东 M. Djamil 医生综合医院使用鼻胃管的诊断、并发症和营养对喂养困难儿童患者体重的影响

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-25 DOI: 10.37275/bsm.v8i6.1008

Riana Youri, Gustina Lubis, F. F. Yani, Aumas Pabuti, Didik Hariyanto, Y. D. Jurnalis, Rinang Mariko

{"title":"Effect of Diagnosis, Complications, and Nutrition for Using Nasogastric Tube to Body Weight of Child Patients with Feeding Difficulty at Dr. M. Djamil General Hospital, Padang, Indonesia","authors":"Riana Youri, Gustina Lubis, F. F. Yani, Aumas Pabuti, Didik Hariyanto, Y. D. Jurnalis, Rinang Mariko","doi":"10.37275/bsm.v8i6.1008","DOIUrl":"https://doi.org/10.37275/bsm.v8i6.1008","url":null,"abstract":"Background: Several conditions in children can cause nutritional intake via the oral route to be inadequate. Providing enteral nutrition via a nasogastric tube (NGT) is an alternative option. Research on the use of NGTs in Indonesia is still limited, so this research aims to determine the effect of NGT use on the weight of pediatric patients with feeding difficulties at Dr. M. Djamil General Hospital, Padang. \u0000Methods: Experimental research with a pre and post-test-only design was conducted on 96 children aged 1 month - 18 years in the children's inpatient room at Dr. M. Djamil General Hospital, Padang. Body weight measurements were carried out before and after using NGT for 4 weeks (January 2022 – January 2023) at the pediatric nutrition and metabolic diseases polyclinic. Data were analyzed using paired t-test and ANOVA. \u0000Results: Most subjects (40.9%) were in the 1-12 month age group. The most common type of nutrition was ONS (oral nutritional supplements) (84.4%), the most common diagnosis was pulmonology (33.3%), and the majority were without complications (72.9%). There is an influence on the child's weight before and after using NGT (p-value <0.01). Significant differences were also found in changes in children's weight with diagnosis and complications (p<0.01). \u0000Conclusion: The use of NGT can increase the weight of pediatric patients who have feeding difficulties at Dr. M. Djamil General Hospital, Padang. Significant differences were found in changes in children's weight by diagnosis and complications.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polycystic Kidney Disease with Breast Nodules in a Male: A Case Report 男性多囊肾伴乳房结节：病例报告

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-18 DOI: 10.37275/bsm.v8i6.999

Caitlyn Natasha Horyono, Borries Foresto Buharman

{"title":"Polycystic Kidney Disease with Breast Nodules in a Male: A Case Report","authors":"Caitlyn Natasha Horyono, Borries Foresto Buharman","doi":"10.37275/bsm.v8i6.999","DOIUrl":"https://doi.org/10.37275/bsm.v8i6.999","url":null,"abstract":"Background: Polycystic kidney disease is a multisystem and progressive congenital kidney disorder characterized by kidney enlargement and the growth of cysts in the kidneys and other organs. Autosomal dominant polycystic kidney disease (ADPKD) is the most common type of inherited kidney disorder and is observed in 1/500 – 1/1000 people. The diagnosis is usually made by a positive family history , and the Ravine ultrasonographic criteria assess the age and number of cysts in both kidneys. \u0000Case presentation: A 37-year-old male was reported with complaints of intermittent hematuria and a painless lump in the right breast for the last 6 years. Patients routinely drink herbal medicine when symptoms appear. Abdominal physical examination revealed renal ballottement. The lump in the right breast is palpable as a lump ± 1 cm from the nipple. No abnormalities in kidney or liver function were found on laboratory examination. Ultrasound was performed, and polycystic kidney disease was obtained in both kidneys and liver, as well as a hypervascular solid nodule in the right breast. The patient was given antibiotics and antifibrinolytics. Healthy lifestyle education is also provided to patients. The patient was then referred for a biopsy of the nodule. \u0000Conclusion: Autosomal dominant polycystic kidney disease (ADPKD) is a common disease but only a few cases of ADPKD are accompanied by nodules in the breast, so a further approach is needed.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"12 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Risk Factors for Increased Intraocular Pressure in Phacoemulsification Surgery: Single Center Study in Jakarta, Indonesia 超声乳化手术中眼压升高的风险因素分析：印度尼西亚雅加达单中心研究

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-13 DOI: 10.37275/bsm.v8i6.998

Nadya Hambali, Syukri Mustafa

{"title":"Analysis of Risk Factors for Increased Intraocular Pressure in Phacoemulsification Surgery: Single Center Study in Jakarta, Indonesia","authors":"Nadya Hambali, Syukri Mustafa","doi":"10.37275/bsm.v8i6.998","DOIUrl":"https://doi.org/10.37275/bsm.v8i6.998","url":null,"abstract":"Background: Phacoemulsification, a common cataract surgery technique, can increase intraocular pressure (IOP) postoperatively. This study aimed to identify risk factors contributing to increased IOP, focusing on patient age and duration of phacoemulsification. \u0000Methods: A cross-sectional study was conducted at Harapan Jayakarta Hospital, Jakarta, for 4 months (May-September 2023) on 43 cataract patients ≥40 years old who underwent phacoemulsification. Inclusion criteria were preoperative IOP 10-21 mmHg, clear conjunctival and corneal structures. Data analysis was carried out univariate and bivariate using SPSS. \u0000Results: Analysis showed a significant correlation between patient age and phacoemulsification duration (older patients = longer phacoemulsification time), with a mean age of 63.21 years. Phacoemulsification duration >270 seconds significantly increases the risk of postoperative IOP. \u0000Conclusion: Prolonged exposure to ultrasonic waves during phacoemulsification can cause cellular injury to the internal structures of the eye, increasing IOP. Identifying modifiable risk factors, such as optimizing phacoemulsification timing, may reduce these complications and improve cataract surgery outcomes.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"1989 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nephrotic Syndrome in a 24-Year-Old Female with Myelodysplastic Syndrome: A Case Report 一名 24 岁女性骨髓增生异常综合征患者的肾病综合征：病例报告

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-13 DOI: 10.37275/bsm.v8i6.997

Cindy Yusliani, Ita Murbani Handajaningrum

引用次数: 0

The Impact of COVID-19 Pandemic on Vitiligo Patient Visits in Tertiary Hospital: A Retrospective Study COVID-19 大流行对三级医院白癜风患者就诊量的影响：回顾性研究

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-04 DOI: 10.37275/bsm.v8i5.992

Rina Gustia, Redha Cipta Utama

{"title":"The Impact of COVID-19 Pandemic on Vitiligo Patient Visits in Tertiary Hospital: A Retrospective Study","authors":"Rina Gustia, Redha Cipta Utama","doi":"10.37275/bsm.v8i5.992","DOIUrl":"https://doi.org/10.37275/bsm.v8i5.992","url":null,"abstract":"Background: Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of the population worldwide. The COVID-19 pandemic lockdown measures significantly affected the readiness of vitiligo patients to contact dermatologists. The aim of this study is to describe vitiligo patient visits during a pandemic situation. \u0000Methods: A retrospective descriptive study, using secondary data obtained from Dr. M. Djamil General Hospital Padang medical records during the period of 2019–2021. \u0000Results: During the pandemic (2020-2021), a total of 7 in 2020 and 19 in 2021 new vitiligo patient have been consulted. The ratio of male/female for two years was 16/10. The age of group 26-24 years had more frequently visited. A total 6 patients had segmental vitiligo and 16 patients had non segmental vitiligo. A total 4 patient had unstable vitiligo. During the pandemic, there were various vitiligo therapy such as oral and topical corticosteroid, topical immunomodulator, phototherapy, and punch grafting surgery. Compare to before the pandemic situation in 2019, a total 25 new vitiligo patient have been consulted in our outpatient clinic. Compared to 2019, the number of visits decrease significantly 72% in 2020 and 24% in 2021. \u0000Conclusion: The pandemic COVID-19 had an unprecedented impact on number of vitiligo patient visits to the tertiary hospitals. This condition may affect visits and patient compliance. There were significant reductions in the number of outpatient visits due to pandemic COVID-19.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"169 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140265719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermoscopy Evaluation of Erythema Dyschromicum Perstans Treated with Combination of Topical Steroid and Narrowband-Ultraviolet B: A Case Report 皮肤镜评估外用类固醇激素和窄带紫外线 B 联合治疗的perstans 失色性红斑：病例报告

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-03-04 DOI: 10.37275/bsm.v8i5.991

Aisha Triani, Satya Wydya, Yenny

{"title":"Dermoscopy Evaluation of Erythema Dyschromicum Perstans Treated with Combination of Topical Steroid and Narrowband-Ultraviolet B: A Case Report","authors":"Aisha Triani, Satya Wydya, Yenny","doi":"10.37275/bsm.v8i5.991","DOIUrl":"https://doi.org/10.37275/bsm.v8i5.991","url":null,"abstract":"Background: Erythema dyschromicum perstans (EDP), also known as ashy dermatosis, is an uncommon, acquired, and persistent skin condition identified by development of hyperpigmented macules of varying sizes on the trunk, face, and extremities. It exact cause is unknown, and there is ongoing debate surrounding its treatment. Dermoscopic assessments may prove beneficial in evaluating the effectiveness of therapeutic interventions. \u0000Case presentation: We present a case of a 20-year-old woman with numerous hyperpigmented macules of brown to slate-grey on her upper trunk, stomach, back, and extremities over the past three years. The patient reported no symptoms such as itching, numbness, or pain. Upon physical examination, mild anemia but otherwise healthy. On physical examination there are multiple brown-grey patches with reddish borders of varying sizes distributed across the body, with unaffected mucosa, scalp, palms, soles, and nails. Dermoscopic examination unveiled a widespread distribution of brown to grey backgrounds with a pinkish homogeneous appearance. Histopathological examination suitable for erythema dyschromicum perstans. The patient received a diagnosis of erythema dyschromicum perstans and underwent treatment involving a combination of topical steroids and Nb-UVB administered three times weekly for a duration of 8 weeks. \u0000Conclusion: This condition presents a cosmetic concern throughout the patient's lifetime and significantly affects their quality of life. After 8 weeks of the combination of topical steroids and Nb-UVB, there was a improvement of erythema and lesion appear lighter. This observation suggests that a treatment with a consistently favorable outcome has not been identified and necessitates further investigation.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"94 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchoscopy Diagnostic Procedures in Central and Peripheral Lesions: A Narrative Literature Review 中央和周边病变的支气管镜诊断程序：文献综述

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-02-26 DOI: 10.37275/bsm.v8i5.983

Syarlidina Syaf, Sri Indah Indriani

引用次数: 0

A Suspicious Cup Disc with High Intraocular Pressure (IOP) and Normal Perimetry: A Rare Self Case Report 可疑杯状圆盘伴高眼压（IOP）和正常视力：罕见的自我病例报告

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-02-26 DOI: 10.37275/bsm.v8i5.982

Mario Abdiwijoyo, Nanda Lessi, Hafni Eka Putri

{"title":"A Suspicious Cup Disc with High Intraocular Pressure (IOP) and Normal Perimetry: A Rare Self Case Report","authors":"Mario Abdiwijoyo, Nanda Lessi, Hafni Eka Putri","doi":"10.37275/bsm.v8i5.982","DOIUrl":"https://doi.org/10.37275/bsm.v8i5.982","url":null,"abstract":"Background: Intraocular pressure (IOP) assessment involves evaluating the force exerted by aqueous humor on the internal surface of the anterior eye. Elevated IOP poses a substantial risk for glaucomatous optic neuropathy and is a key modifiable clinical risk factor. This study aims to explore cases of ocular hypertension coupled with optic nerve cupping, suspected to be glaucoma, providing comprehensive details of examination results, diagnosis, and subsequent management. \u0000Case presentation: A 23-year-old Asian male underwent an ocular examination, revealing average IOP levels measured using non-contact tonometry. Despite no complaints, consecutive measurements noted 28 mmHg for the right eye and 26 mmHg for the left eye. Initial assessments by a glaucoma specialist indicated open-angle anterior chambers. Optical coherence tomography revealed cup disc ratios of 0.7 to 0.8 for both eyes. Medication (Timol) was prescribed, adjusting with oral citicoline and brinzolamide. The diagnosis evolved to juvenile open-angle glaucoma (JOAG). Visual field testing showed normal results. Discontinuation of treatment led to reclassifying the diagnosis as ocular hypertension and scheduling follow-up OCT examinations for five years. \u0000Conclusion: The patient exhibited corneal thickness ≥610 μm, CDR ≥0.7 μm, IOP >25 mmHg, and maintained good visual field conditions. Additional research is essential to understand the correlation between corneal thickness and other eye conditions. Recognizing potential overdiagnosis due to high IOP and large CDR emphasizes the need for meticulous clinical assessment and advanced diagnostic examinations to distinguish physiological and pathological conditions.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"44 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140431611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Complexities of Colorectal Cancer: A Case Report 大肠癌的复杂性：病例报告

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-02-26 DOI: 10.37275/bsm.v8i5.984

Intan Fredika Bahari, Mohamad Arifin

{"title":"The Complexities of Colorectal Cancer: A Case Report","authors":"Intan Fredika Bahari, Mohamad Arifin","doi":"10.37275/bsm.v8i5.984","DOIUrl":"https://doi.org/10.37275/bsm.v8i5.984","url":null,"abstract":"Background: Colorectal cancer (CRC) is a malignancy that originates from the colon tissue (ascending, transverse, descending, sigmoid colon) and rectal tissue. Colorectal cancer is the fourth most common cancer in the world, and the second leading cause of cancer death. In Indonesia (2020), colorectal cancer was ranked sixth of the all malignancy diagnoses with a total of 17,368 new cases (4,4%). \u0000Case presentation: a case of colon cancer (mucinous adenocarcinoma) in a 70 year old woman. Diagnosis was based on anamnesis of the presence onf intermitten abdominal pain, a mass in the right iliac region of the abdomen, and defecation accompanied by blood. On physical examination, there was tenderness and a mass in the right iliac region, and a positive Carnett’s sign. computer tomography (CT) of the urinary tract without contrast was performed and revealed a mass was found in the right abdomen, suspicious for the ascending colon and hepatic flexure of the colon, a cyst with a diameter of ± 3cm in the right kidney. \u0000Conclusion: Anatomical patology (microscopic) results showed mucinous adenocarcinoma. The treatment for this patient was exploratory laparotomy, right hemicolectomy, and end to end anastomosis. \u0000 ","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"26 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Activated Growth Factor (AGF) from Platelets on Alpha-SMA Levels in Osteoarthritis: Invivo Study 血小板活化生长因子 (AGF) 对骨关节炎患者 Alpha-SMA 水平的影响：活体研究

Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2024-02-22 DOI: 10.37275/bsm.v8i5.980

Ziske Maritska, Rachmat Hidayat, Septi Purnamasari, Muhammad Rizky Hidayatullah, Sarah, Najla Khairunnisa

{"title":"The Effect of Activated Growth Factor (AGF) from Platelets on Alpha-SMA Levels in Osteoarthritis: Invivo Study","authors":"Ziske Maritska, Rachmat Hidayat, Septi Purnamasari, Muhammad Rizky Hidayatullah, Sarah, Najla Khairunnisa","doi":"10.37275/bsm.v8i5.980","DOIUrl":"https://doi.org/10.37275/bsm.v8i5.980","url":null,"abstract":"Background: The most prevalent joint condition and leading contributor to disability is osteoarthritis (OA), resulting in a significant socio-economic impact. It occurs due to an imbalance of pro-inflammatory and anti-inflammatory mediators, influencing anabolic and catabolic activities. This study aims to determine the effect of activated growth factor (AGF) on alpha-SMA levels. \u0000Methods: This research is an in vivo post-test-only control group experimental study conducted at the Eureka Research Laboratory. Thirty male Wistar rats were divided into five treatment groups: normal control group, negative control group, AGF I group (TGF-β 100 pg/mL), AGF II group (TGF-β 1000 pg/mL), and AGF III group (TGF-β 10,000 pg/mL). AGF was obtained from rat blood intravenously and centrifuged at a predetermined speed. Growth factor activation was performed by adding 10% CaCl2, and then TGF-β levels were measured. All groups of rats were acclimatized for 7 days. After that, osteoarthritis was induced with intra-articular injection of monoiodoacetate (MIA) 4.8 mg/60μL in all groups of rats except the normal control group. Next, rats were given treatment according to the group for 21 days. On the 21st day, rats were euthanized, and alpha-SMA levels were measured using the sandwich method ELISA kit. \u0000Results: Sequentially, the mean Alpha-SMA levels for each group in pg/mL were: 91.495 ± 2.36; 10.682 ± 1.09; 30.502 ± 2.00; 52.892 ± 1.29; and 76.180 ± 2.65. In the AGF group, there was an increase in alpha-SMA levels directly proportional to the dose of TGF-β injected. \u0000Conclusion: AGF has an effect on increasing alpha-SMA levels in the joints of rats with a model of osteoarthritis.","PeriodicalId":503226,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"4 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140438684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0