Asian Journal of Health Research最新文献_第2页

Is There Endometriosis Effect on Economic Burden? 子宫内膜异位症对经济负担有影响吗？

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.132

MD PhD OG Sutrisno, Rei, Sutrisno Sutrisno

{"title":"Is There Endometriosis Effect on Economic Burden?","authors":"MD PhD OG Sutrisno, Rei, Sutrisno Sutrisno","doi":"10.55561/ajhr.v2i3.132","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.132","url":null,"abstract":"Endometriosis is a chronic inflammation with a specific characteristic being the appearance of endometrial-like tissue outside the uterus. Symptoms of endometriosis are usually non-specific and can be found to be similar to symptoms of other gynecological and even gastrointestinal disorders. The nature of the disease, enigmatic and needs more cost at every step, stimulate the economic burden in managing endometriosis. The important variable that has a significant role in the economic burden of endometriosis is the recurring nature of this condition, even up to 40-45%. I selected online articles using PRISMA and obtained 122 articles, 4 articles being deleted because of no full text, 8 articles being deleted because of duplication, 17 articles being deleted because of the age of articles more than 10 years, 80 articles being deleted because of not fully relevant with main topics, 4 articles being deleted because of the burden not specific in the economic aspect, and 9 articles are the most perfect choice related with the main topics. In conclusion, endometriosis is a chronic disease experienced by women mostly of productive age, which affects the quality of life, fertility, and even direct economic burdens in the form of recurring and long-term health expenses as well as indirect economic burdens in the form of productivity, many absences from work, and excessive leave. Often due to the treatment process. Based on several journals with similar discussions show significant results in the influence of endometriosis on economic burden. .","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"66 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.126

Yessi Rahmawati, Joko Prasetyo, Ratna Wardani

{"title":"Factors Related to Conservative Preterm Therapy on BPJS Claim Achievement in Waluyo Jati Hospital Probolinggo Regency","authors":"Yessi Rahmawati, Joko Prasetyo, Ratna Wardani","doi":"10.55561/ajhr.v2i3.126","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.126","url":null,"abstract":"Introduction: A high number of reports of preterm incidents in Probolinggo, which was the highest in East Java in 2018, has caused problems in the financing process claimed by the Indonesian National Social Health Insurance (Badan Penyelenggara Jaminan Sosial (BPJS)). Insufficient financing for maternity mothers, as the highest proportion of national delivery methods, can certainly be a direct or indirect obstacle to the maternal mortality rate, which is still very high in Indonesia. This research aims to analyze the influence of hospitalization period, gestational age, and delivery method in conservative preterm therapy on BPJS claim achievement at Waluyo Jati Hospital, Probolinggo Regency. Material and Methods: This study is a quantitative research with a cross-sectional approach. Sampling took place from May to September 2023 at Waluyo Jati Regional Hospital, Probolinggo Regency. Sampling used an accidental sampling technique. 33 respondents participated in this research. Results: The results of this study showed that the largest number of respondents with the criteria for a length of stay of 4-7 days was 23 respondents (69.6%), gestation age 31-33 weeks was 14 respondents (42.4%), and 23 respondents underwent cesarean section delivery (69.7%). The highest BPJS claim achievement value was in the range of 30-50%, with 18 respondents (54.5%). The results of the Multiple Linear Regression showed a p-value of 0.000. Conclusion: The conclusion from this research is that there is an influence of hospitalization period, gestational age, and delivery method simultaneously in conservative preterm therapy on the achievement of BPJS claims at Waluyo Jati Hospital, Probolinggo Regency.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"49 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Genistein on Proliferating Cell Nuclear Antigen (PCNA) Expression and Vascular Density in The Peritoneum of Endometriosis Mice Model 染料木素对子宫内膜异位症小鼠腹膜中增殖细胞核抗原 (PCNA) 表达和血管密度的影响

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.104

Ikatan Dokter, Indonesia Wilayah, Jawa Timur, Anggia Prameswari Wardhana, Yahya Irwanto

{"title":"Effect of Genistein on Proliferating Cell Nuclear Antigen (PCNA) Expression and Vascular Density in The Peritoneum of Endometriosis Mice Model","authors":"Ikatan Dokter, Indonesia Wilayah, Jawa Timur, Anggia Prameswari Wardhana, Yahya Irwanto","doi":"10.55561/ajhr.v2i3.104","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.104","url":null,"abstract":"Introduction: Survival of endometriosis lesions depends on the formation of blood vessels, cell proliferation, and oxygen supply. Their vascular densities can evaluate the vascularity of ectopic endometriosis tissues. Proliferating Cell Nuclear Antigen (PCNA) is one of the markers of cell proliferation that affects the growth of endometriotic lesions. Genistein is an isoflavone component that highly potential effect as an anti-angiogenic and inhibiting proliferation through the binding capacity to estrogen receptors. Material and Methods: This experimental study uses the Stored Biological Materials of mice peritoneum tissue. The paraffin block was divided into six groups, which are the negative control group, positive control group, and four treatment groups with genistein doses of 1.3 mg/day, 1.95 mg/day, 2.6 mg/day, and 3.25 mg/day. Immunohistochemical techniques and hematoxylin-eosin for vascular densities examined PCNA expressions. Preparation analysis uses OLIVIA software. Preparation calculations are done manually with cell count software. Observations were analyzed with the ANOVA test and Dunnett T3 5% test. Results: Based on analysis with ANOVA, there was a significant difference in PCNA expression and vascular densities because of the effect of genistein in various doses with a p-value of 0.001 (p<0.05). Based on Dunnett T3 5% test increase of PCNA expression by giving genistein doses 1,3 mg/day, 1,95 mg/day, and 2,6 mg/day, a reduction in dose of 3,25 mg/day. Vascular densities reduced significantly in all treatment groups. Conclusion: Administration of genistein in various doses significantly increases PCNA expression but reduces PCNA expression in a dose of 3.25 mg/day and significantly reduces vascular densities.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"44 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guidelines for Health System Management for Cambodia, Laos, Myanmar, and Vietnam (CLMV) Medical Tourists in the Regional Provinces of Thailand 柬埔寨、老挝、缅甸和越南 (CLMV) 医疗旅游者在泰国各地区省份的卫生系统管理指南

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.117

Chainarong Srirak, Patthaphon Sukjai

{"title":"Guidelines for Health System Management for Cambodia, Laos, Myanmar, and Vietnam (CLMV) Medical Tourists in the Regional Provinces of Thailand","authors":"Chainarong Srirak, Patthaphon Sukjai","doi":"10.55561/ajhr.v2i3.117","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.117","url":null,"abstract":"Introduction: Medical tourism refers to any person who travels cross-border to a foreign country to receive medical services. The Thai government has set a strategy to make Thailand a medical hub to drive economic growth in the future. The purpose of this research was to conduct an analysis of health system management for Cambodia, Laos, Myanmar, and Vietnam (CLMV) medical tourists in regional provinces of Thailand. Methods: This research was qualitative research. The in-depth interview was conducted with 25 cases, and the focus group was conducted with 30 representatives of government agencies and private entrepreneurs involved in policies, together with document analysis. The content analysis was applied for data analysis. Results: It was found that the guidelines for health system management for CLMV medical tourists in regional provinces, namely adjusting the medical payment system, tightening screening of treatment eligibility, cooperating internationally in the management of the International Health Insurance Fund, establishing a medical fund for those who do not have Thai citizenship; establish foreign patients department in government hospitals; and control appropriate and fair service rates. Conclusion: Practical short-term factors include promoting targeted niche markets, establishing marketing partnerships with other businesses, supporting medical tourism, making a database of expertise of hospitals in Thailand and training doctors with specialized expertise, especially international programs, promoting research, development and production of medical equipment and medical supplies, and encourage private hospitals in Thailand to be certified important in increasing Cambodia, Laos, Myanmar and Vietnam (CLMV) Medical Tourists in the Regional Provinces of Thailand.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"857 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139179107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Herbal Medicine as An Alternative Treatment Option for Endometriosis: A Literature Review 草药作为子宫内膜异位症替代疗法的作用：文献综述

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.125

Sutrisno Sutrisno, Putri Nadia Paramadina

{"title":"The Role of Herbal Medicine as An Alternative Treatment Option for Endometriosis: A Literature Review","authors":"Sutrisno Sutrisno, Putri Nadia Paramadina","doi":"10.55561/ajhr.v2i3.125","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.125","url":null,"abstract":"Introduction: Endometriosis is a benign gynecological disorder characterized by ectopic growth of endometrial tissue. This condition may deteriorate patient’s quality of life due to pain as its main manifestation and its complications, including impaired fertility and risk of ovarian cancer. Current standard endometriosis treatment still yields numerous side effects and controversy. Thus, herbal medicine is hoped to be the safer alternative treatment with excellent efficacy for endometriosis. Methods: The search of literature published in English or Bahasa Indonesia was performed by incorporating the search queries “endometriosis”, “herbal therapy”, “silymarin”, “curcumin”, “Viburnum opulus”, “Pueraria”, “Allium sativum”, “black garlic”, “naringenin” on databases including PubMed, Cochrane, Springer, Science Direct, Nature, and Google Scholar. The studies included were in vitro studies, in vivo studies, and clinical trials. Results: Various herbal treatments have been widely studied regarding their anti-inflammatory, antioxidant, neuroprotective, hepatoprotective, cardioprotective, antiallergy, and immunomodulatory capacity. A lot of herbal compounds have the potential to suppress and manage endometriosis through various mechanisms, such as inhibiting the migration and adhesion of endometriosis to other tissues, suppressing inflammatory response in endometriosis pathogenesis, generating antioxidant, inhibiting estrogen activity, and inducing apoptosis of endometriosis cell through a number of signaling pathways. Conclusion: Herbal medicine has the potential to manage endometriosis through various mechanisms. Further research is needed regarding the efficacy of herbal therapy in managing endometriosis.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139179454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fertility Desires of HIV-positive Women Attending Care and Treatment Clinics (CTC) in Urban Areas in Tanzania 坦桑尼亚城市地区在护理和治疗诊所（CTC）就诊的艾滋病毒抗体阳性妇女的生育愿望

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.123

Ikatan Dokter, Indonesia Wilayah, Jawa Timur, Aleswa Zebedayo, Oscar Mukasa, Samwel Analanga, Irene Moshi, I. Msuya, Francis Levira

{"title":"Fertility Desires of HIV-positive Women Attending Care and Treatment Clinics (CTC) in Urban Areas in Tanzania","authors":"Ikatan Dokter, Indonesia Wilayah, Jawa Timur, Aleswa Zebedayo, Oscar Mukasa, Samwel Analanga, Irene Moshi, I. Msuya, Francis Levira","doi":"10.55561/ajhr.v2i3.123","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.123","url":null,"abstract":"Introduction: Reproductive concerns by People Living with HIV (PLHIV) are matters that are important for both individual and general public health. We described fertility desire among HIV-positive women attending Care and Treatment Clinics (CTC) and determined factors for having such a desire to get children in urban areas of Dar es Salaam and Dodoma in Tanzania. Material and Methods: Cross-sectional study for which primary data were collected in a random sample of women of reproductive age (15-49 years) after accessing HIV care and treatment services. A survey was conducted among HIV-positive women receiving anti-retroviral treatment to document service needs, service quality, and fertility preferences. A Univariate model was used to examine the relationship between the dependent and the independent variables, and all associations were taken into account in the final model. Results: Among 691 participants, 282 (40.8%) women living with HIV have fertility desire. Women aged above 25 experienced a reduction in the odds of fertility desire by 56% (P value =0.003) compared to the reference group of women aged 25 years or less. Fertility desire was predicted to have two times as much growth with 1 to < 3 years (p- value=0.02) and 5 or 5+ years (P value =0.01) time lapse since the debut of ART, compared to the group of women who were on ART for 3 years but less than five years. Conclusion: Our data has not only reconfirmed the importance of ART and PMTCT services to PLHIV but also contributed to evidence on their value addition in terms of the creation of resilience to normal fertility family life after debut HIV diagnosis.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"212 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139179784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Huge Vaginal Prolapse of Uterine Leiomyoma Complicated with Cervical Inversion: A Case Report 子宫肌瘤巨大阴道脱垂并发宫颈内翻：病例报告

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.129

Ratih Frastika Dewi, L. Farida

{"title":"A Huge Vaginal Prolapse of Uterine Leiomyoma Complicated with Cervical Inversion: A Case Report","authors":"Ratih Frastika Dewi, L. Farida","doi":"10.55561/ajhr.v2i3.129","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.129","url":null,"abstract":"Introduction: Uterine fibroids are non-malignant neoplasms originating from the smooth muscle cells of the uterus, and they represent the most prevalent tumor seen within the female reproductive system. The primary established approach to manage this condition is surgical interventions, specifically myomectomy, hysterectomy, or hysteroscopic removal of small subserous nodules. Occasionally, submucous fibroids may protrude through the cervical os, thereby enabling the feasibility of performing a vaginal hysterectomy. Case Presentation: The clinical presentation of a 44-year-old multiparous woman who arrived with symptoms of vaginal bleeding and a sizable mass protruding through the vaginal opening. The patient underwent an emergency vaginal extraction to remove the mass measuring 24 cm in the emergency room and a scheduled for elective surgery. During the procedure, uterine inversion was found with a muscle bundle around the corpus uteri and a fourth-grade perineal tear. This patient was also planned for a total abdominal hysterectomy and bilateral-salphyngo-oophorectomy procedure, along with Haultain's procedure and perineal repair. The patient exhibited favorable surgical outcomes. Conclusion: Hysterectomy is the preferred therapy for prolapsed pedunculated submucous myoma. It has been seen that even exceptionally big nascent myomas can be effectively removed using vaginal means.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"61 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139179387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Flavonoid Extract from Phaleria macrocarpa to Proliferating Factors (MMP-1, MMP-3, MMP-7) in Endometriosis Mice Model 大戟黄酮提取物对子宫内膜异位症模型小鼠增殖因子（MMP-1、MMP-3、MMP-7）的影响

Asian Journal of Health Research Pub Date : 2023-12-14 DOI: 10.55561/ajhr.v2i3.102

Yahya Irwanto, Teguh Wiyono, Kusuma Wardani

{"title":"The Effect of Flavonoid Extract from Phaleria macrocarpa to Proliferating Factors (MMP-1, MMP-3, MMP-7) in Endometriosis Mice Model","authors":"Yahya Irwanto, Teguh Wiyono, Kusuma Wardani","doi":"10.55561/ajhr.v2i3.102","DOIUrl":"https://doi.org/10.55561/ajhr.v2i3.102","url":null,"abstract":"Introduction: Endometriosis is an inflammatory disease influenced by estrogen characterized by ectopic growth of the endometrial stroma and glands. Matrix metalloproteinase (MMP) is a proteolytic enzyme that has an important role in the remodeling of the extracellular matrix in normal tissues but also contributes to pathologies such as tumor invasion. The therapy has many drawbacks, including being expensive and in need of herbal therapy as an alternative. Phaleria macrocarpa is a native plant of Indonesia that contains flavonoids. This study aimed to evaluate the effect of Phaleria macrocarpa flavonoid isolate on the development of apoptosis, proliferation, and angiogenesis in mice model endometriosis. Material and Methods: This research is a true experimental study with a Randomized Post-Test Only with a Control Group in the laboratory. Samples are divided into six groups, a control group and an intervention group, administered with flavonoid extract from Phaleria macrocarpa. Data analysis was carried out by using the Independent T-Test with SPSS for Windows 19.0 software. Results: Each control and intervention group consisted of 6 mice. The normality test for each variable shows p> 0.05. Administration of flavonoid in each group shows a significant decrease in MMP-1 (20.4 ± 7.74 vs 65.68 ± 10.97, p=0.000), MMP-3 (53.34 ± 9.66 vs67.47 ± 10.05, p=0.000), and MMP-7 expression (40.52 ± 5.43 vs 54.13 ± 4.08, p=0.000). Conclusion: Flavonoids from the Phaleria macrocarpa fruit extract were able to reduce the expression of MMP-1, MMP-3, and MMP-7 in mice model endometriosis.","PeriodicalId":502351,"journal":{"name":"Asian Journal of Health Research","volume":"367 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139179227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0