International Journal Of Community Medicine And Public Health最新文献

{"title":"Microbial challenges and solutions in root canal therapy","authors":"Norah Fahad Al Ajmi, May Khalid Alshenaifi, Mada Mohammed Binsalem, Khalid Abdullah Alahmary, Noha Abdullah Al Shahrani, Abdulrahman Mohammed Alasim, Fahad Rashed Alotaibi, Abdulwahab Saleh Ali, Sameeh Mansour Attar, Nourah Mobarek Al Shahrani","doi":"10.18203/2394-6040.ijcmph20242271","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20242271","url":null,"abstract":"Root canal therapy (RCT) faces significant challenges due to microbial invasion and biofilm formation within the root canal system. The intricate anatomy of root canals, including isthmuses, lateral canals, and apical deltas, provides a conducive environment for pathogenic microorganisms, complicating effective disinfection. Key pathogens such as Enterococcus faecalis and Candida albicans are highly resilient, capable of forming biofilms that protect them from antimicrobial agents and host defences. Current antimicrobial strategies in endodontics combine mechanical instrumentation with chemical disinfection. Mechanical debridement, though essential, often falls short of thoroughly cleaning the complex root canal anatomy. Sodium hypochlorite (NaOCl), the gold standard irrigant, exhibits broad-spectrum antimicrobial properties but struggles to penetrate biofilms and dentinal tubules fully. Adjunctive solutions like chlorhexidine (CHX) and ethylenediaminetetraacetic acid (EDTA) enhance the antimicrobial efficacy of NaOCl by providing prolonged action and removing the smear layer, respectively. Intracanal medicaments, such as calcium hydroxide (Ca(OH)2), are utilized to maintain antimicrobial activity between treatment sessions. Despite its high pH and effectiveness against a wide range of bacteria, Ca(OH)2 shows limited efficacy against biofilm-forming bacteria like Enterococcus faecalis. Innovations in irrigation techniques, such as passive ultrasonic irrigation (PUI) and laser-activated irrigation (LAI), have improved the delivery and activation of irrigants, enhancing their ability to disrupt biofilms and penetrate the root canal system. Nanoparticle-based irrigants and medicaments represent a promising advancement in endodontic disinfection. Their small size and large surface area allow for better penetration and interaction with bacterial cells, significantly reducing bacterial load in the root canal system. Combining traditional and advanced antimicrobial strategies is essential for overcoming the limitations of current methods and improving the success rates of endodontic therapy. Understanding the mechanisms of microbial invasion and biofilm formation, along with integrating emerging technologies, can lead to more effective disinfection protocols. This approach aims to enhance treatment outcomes and ultimately ensure the longevity of endodontically treated teeth.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evolution of adhesive dentistry: a review of materials and techniques","authors":"T. M. Alotaibi, Rawan K. Alhazmi, Faisal S. Aldrees, H. A. Alsakran, Majed F. Alotaibi, Monerah H. Alshathri, Omar S. Alqahtani, Ziad N. Almutawa, Manal M. Alsaadoun, Fahad I. Fatiny","doi":"10.18203/2394-6040.ijcmph20241986","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241986","url":null,"abstract":"Adhesive dentistry has undergone remarkable advancements since its inception, fundamentally transforming restorative dental care. Initially marked by the development of early resins and etching techniques, adhesive dentistry has evolved to incorporate sophisticated materials and innovative techniques that significantly enhance clinical outcomes. The introduction of Bis-GMA resins in the 1960s improved mechanical properties and reduced polymerization shrinkage, paving the way for modern composite resins. These composites, enhanced by nanotechnology and advanced filler technology, provide superior strength, wear resistance, and esthetic qualities. Techniques such as selective enamel etching and multi-layering of adhesive systems have further improved bond strength and reduced technique sensitivity. The clinical applications of adhesive dentistry are extensive, ranging from direct and indirect restorations to cosmetic procedures and preventive measures. Direct composite restorations offer minimally invasive solutions with excellent esthetics, while indirect restorations such as inlays, onlays, and veneers benefit from strong, reliable bonds and improved durability. Cosmetic procedures, including veneers, achieve dramatic esthetic improvements with long-lasting results. Preventive applications, such as sealants, effectively protect against caries, especially in pediatric and high-caries-risk patients. The continuous refinement of materials and techniques has led to better clinical outcomes, increased patient satisfaction, and reduced need for invasive procedures. Advances in adhesive materials and methods have ensured that restorations not only mimic natural tooth structures but also maintain their integrity under functional forces. As research and development in adhesive dentistry continue to progress, the field is poised to offer even more innovative and effective solutions, further enhancing the quality of dental care. Overall, the evolution of adhesive dentistry underscores its pivotal role in modern dental practice, providing durable, esthetic, and reliable restorative options that meet the diverse needs of patients.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"22 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical innovations in correcting severe malocclusions","authors":"Madhawi Faisal Alshammri, Amjad Awadh Alazmi, Khalid Waleed Tarabzouni, Latifa Hamad Alshayea, N. Almalik","doi":"10.18203/2394-6040.ijcmph20241988","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241988","url":null,"abstract":"The correction of severe malocclusions presents significant challenges in orthodontics due to the complexity and precision required for effective treatment. Recent biomechanical innovations have transformed the landscape of orthodontic care, offering more precise, efficient, and patient-friendly solutions. Advancements in orthodontic bracket systems, including the development of self-ligating brackets and heat-activated arch wires, have enhanced the control and comfort of tooth movements, reduced treatment times and improving patient outcomes. Temporary anchorage devices (TADs) have provided stable anchorage points, enabling complex tooth movements that were previously difficult to achieve. TADs have proven particularly effective in managing open bites and class II malocclusions, offering non-surgical alternatives for severe cases. The integration of digital technology in orthodontics, such as 3D imaging and computer-aided design/manufacturing (CAD/CAM), has further revolutionized treatment planning and execution. These technologies facilitate accurate diagnostics and the creation of customized orthodontic appliances, ensuring precise and predictable treatment outcomes. Clear aligner therapy, initially limited to simple cases, has advanced through the use of improved thermoplastic materials and digital customization, allowing for the treatment of more complex malocclusions. Innovative force application techniques, including the use of attachments and elastics, have expanded the capabilities of aligners, making them a versatile and effective alternative to traditional braces. Collectively, these biomechanical innovations have significantly improved the management of severe malocclusions, enhancing treatment efficiency, precision, and patient comfort. The ongoing development of these technologies promises to further advance the field of orthodontics, providing more effective and aesthetically pleasing solutions for patients with complex dental alignment issues.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"61 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health in obese children common findings, prevention, treatment, and outcome","authors":"Rana S. Salmin, Wael S. Bin-Saeed, Reem A. Albakr, Nouf I. Alkhalid, Noura S. Alqahtani, Rana A. Alwahib, Ali S. Arab, Sarah F. Alhazmi, D. M. Alharbi, May M. Alotaibi","doi":"10.18203/2394-6040.ijcmph20241987","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241987","url":null,"abstract":"Childhood obesity is a significant global public health issue, closely linked to various oral health challenges, including dental caries, periodontal disease, and malocclusion. Obese children are more prone to these dental problems due to dietary habits that include high sugar and carbohydrate intake, poor oral hygiene practices, and systemic inflammation. This review explores the common oral health issues faced by obese children and emphasizes the importance of preventive strategies and tailored treatment approaches. Preventive measures include promoting healthy dietary habits, improving oral hygiene practices, and ensuring regular dental check-ups. Dietary modifications, such as reducing the intake of sugary snacks and beverages, play a crucial role in preventing tooth decay and other dental problems. Educating children and caregivers about proper brushing and flossing techniques and the use of fluoride toothpaste and dental sealants further supports oral health. Regular dental visits allow for early detection and management of dental issues, with professional cleanings, fluoride treatments, and appropriate restorative and periodontal therapies being integral components of care. The outcomes of these comprehensive treatment strategies are generally positive, leading to improved oral health and overall quality of life for obese children. Multidisciplinary collaboration among healthcare providers, including dentists, pediatricians, and nutritionists, is essential to develop effective care plans that address both obesity and oral health. This integrated approach ensures that obese children receive holistic care that promotes lifelong healthy habits, reducing the risk of future dental and systemic health problems. The review underscores the necessity of a concerted effort to address the intertwined issues of obesity and oral health in children, highlighting the potential for significant health improvements through targeted prevention and treatment strategies.\u0000 ","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"6 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing leadership in disaster preparedness and response lessons learned and future directions","authors":"Amnah Mohammed Thrwi, Afaf Mousa Al Hazmi, Amani Mawadh Kalfout, Hadiah Mohammed Kariri, Thakra Yousef Aldabyan, Zenab Hassan Alsalah","doi":"10.18203/2394-6040.ijcmph20241989","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241989","url":null,"abstract":"Nursing leadership is integral to effective disaster preparedness and response, demanding agility, strategic planning, and robust resource management. Disasters, both natural and man-made, present unique challenges that require nursing leaders to be adept in rapid decision-making and efficient coordination. The unpredictability of disasters necessitates comprehensive and regularly updated preparedness plans, ensuring nursing teams are well-versed in their roles through continuous training and simulations. Interprofessional collaboration and strong community partnerships are essential, fostering a unified response and efficient resource distribution. Communication remains a cornerstone of disaster management, with clear, timely information dissemination being crucial for coordinating efforts and maintaining public trust. Resource scarcity during disasters, such as shortages of medications and personal protective equipment (PPE), poses significant challenges. Effective resource management strategies are essential to maintain patient care standards and protect healthcare workers. The psychological toll on healthcare providers is another critical issue, with nursing leaders needing to implement support systems that address mental health and promote resilience. Integrating advanced technologies like telehealth and data analytics can enhance disaster response, providing remote care options and enabling predictive modeling for better resource allocation. Innovative approaches in nursing leadership include the use of telehealth for remote consultations and monitoring, data analytics for predictive modeling, and interprofessional education to improve teamwork and coordination. Strengthening community partnerships enhances overall disaster response capacity, ensuring that community-specific needs are addressed. Mental health support for healthcare providers, both immediate and long-term, is vital for maintaining a resilient workforce. Policy advocacy by nursing leaders is crucial to developing robust disaster preparedness frameworks and securing adequate funding. In summary, nursing leadership is pivotal in disaster preparedness and response, with a focus on strategic planning, interprofessional collaboration, effective communication, resource management, mental health support, and the integration of advanced technologies. Emphasizing these areas will enhance the resilience and responsiveness of healthcare systems, ultimately improving outcomes for patients and healthcare providers during disasters.\u0000 ","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"39 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the interplay between diet and oral inflammation","authors":"R. A. Alghamdi, Hala A. Alzamil, Haya A. Alzamil, Rawan Y. Alotaibi, Sara M. Albishi, Amro M. Sallam, Nasser S. Alhufaiyan, Esraa M. Alahdal, Dania A. Baeesa, Sara M. Aljohani","doi":"10.18203/2394-6040.ijcmph20241985","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241985","url":null,"abstract":"The relationship between diet and oral inflammation is intricate and significant, influencing overall periodontal health through various mechanisms. Nutritional factors such as vitamins, minerals, and bioactive compounds play pivotal roles in either exacerbating or mitigating inflammatory processes in the oral cavity. Vitamin C, essential for collagen synthesis and tissue repair, along with calcium, critical for bone health, are key nutrients that support periodontal health by reducing susceptibility to gingival inflammation and periodontitis. Polyphenols, abundant in fruits, vegetables, and tea, exhibit strong anti-inflammatory properties that protect against oxidative stress and inflammation in oral tissues. Dietary patterns also have a profound impact on oral health. The Mediterranean diet, rich in fruits, vegetables, whole grains, and healthy fats, has been associated with lower levels of periodontal inflammation due to its high content of antioxidants and polyphenols. Conversely, the Western diet, characterized by high consumption of refined carbohydrates, sugars, and saturated fats, is linked to increased periodontal disease risk, promoting hyperglycemia and insulin resistance that exacerbate inflammatory responses. Vegetarian and plant-based diets, which emphasize the intake of anti-inflammatory and antioxidant-rich foods, are associated with better periodontal health markers, including lower bleeding on probing and reduced periodontal pocket depth. Antioxidants and anti-inflammatory nutrients are crucial in combating oxidative stress and reducing inflammation, essential for maintaining oral health. Vitamin E, coenzyme Q10, omega-3 fatty acids, and green tea polyphenols are particularly beneficial, reducing oxidative damage and inflammation in periodontal tissues. Dietary strategies incorporating these nutrients effectively support oral health and can be part of a comprehensive approach to preventing and managing periodontal disease. Diet plays a critical role in oral health, influencing periodontal inflammation through specific nutrients and overall dietary patterns. Emphasizing the intake of antioxidant-rich and anti-inflammatory foods, while minimizing harmful dietary components, is fundamental in promoting and maintaining periodontal health.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"36 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in health informatics for monitoring perioperative patient data","authors":"Khaled B. Hawsawi, Ahmad M. Faqihi, Naif H. Albalaji, Ali M. Alsultan, Sami H. Alharbi, Farrag M. Almeglad, Fahad A. Alhajri","doi":"10.18203/2394-6040.ijcmph20241984","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241984","url":null,"abstract":"Advancements in health informatics are revolutionizing perioperative care by enhancing patient monitoring, improving clinical decision-making, and promoting patient safety. The integration of electronic health records (EHR) facilitates seamless information flow across all perioperative stages, ensuring up-to-date patient data is accessible to the entire healthcare team. This accessibility reduces errors, improves coordination, and enhances overall patient outcomes. EHR systems also support standardized documentation, reducing variability in record-keeping and ensuring comprehensive patient information is consistently captured. Real-time data analytics and predictive modeling are powerful tools in perioperative settings, enabling clinicians to anticipate and manage potential complications proactively. By analyzing vast datasets, predictive models identify patterns and risk factors associated with adverse outcomes, allowing for targeted interventions and personalized care plans. Real-time analytics provide continuous monitoring of patient status during surgery, offering immediate feedback and enabling prompt adjustments to ensure patient stability. Wearable devices and remote monitoring systems further augment real-time data analytics by continuously tracking physiological parameters throughout the surgical process and into the postoperative period. This continuous data stream allows for ongoing assessment of patient status and early detection of complications, enhancing patient safety and outcomes. Health informatics solutions, including automated alerts and decision support tools, minimize human error and ensure adherence to clinical guidelines. Automated reminders for critical actions, such as timely antibiotic administration, significantly reduce the incidence of surgical site infections. Decision support tools provide real-time, evidence-based recommendations at the point of care, supporting clinicians in making informed decisions and improving patient outcomes. Additionally, health informatics facilitates continuous quality improvement by enabling the collection and analysis of performance data, informing targeted interventions and process improvements. Overall, advancements in health informatics are transforming perioperative care, offering numerous benefits in terms of efficiency, accuracy, and patient safety, ultimately leading to better patient outcomes and higher quality of care. Continued innovation in this field will be essential for maintaining and improving the standards of perioperative care.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"65 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of prevalence of minimum acceptable diet and associated factors among children aged 6-24 months in rural Gurugram, Haryana, India","authors":"S. Vashist, Nidhi Gupta, Narendra Singh, Bhawna, S. Chamola","doi":"10.18203/2394-6040.ijcmph20241976","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241976","url":null,"abstract":"Background: Infant and young child feeding (IYCF) is the key area to improve survival of child and promotion of growth and development of the child. For assessing the IYCF for children aged 6-24 months, minimum acceptable diet (MAD) is one of the core indicators. A community based cross sectional study was done to assess the MAD and its associated factors among children aged 6-24 months in rural Gurugram, Haryana.\u0000Methods: A sample of 200 mother-child dyads were interviewed. Majority of children (90.1%) did not receive MAD.\u0000Results: The proportion of children who has received minimum diet diversity (MDD) and minimum meal frequency (MMF) were 14% and 61% respectively. More than three fourth (77.5%) of children consumed junk food in last 24 hours dietary recall.\u0000Conclusions: Counselling of mothers, encouraging involvement of fathers and extended family members in adequate feeding practices was done.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":" 1103","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of public health policies on reducing tobacco and substance abuse among the community","authors":"Aljazi Khuzaim Alonazi, Fayz Mohammed Almutairi, Abdullah Mohammed Aljandabi, Basil Ahmed Alanazi, Daliyah Alruwaili, Abdulrhman Olayan Al Mutairi, Ziyad Mansour Alzahrani, Saleh Mohammed Alsaif, Majed Sulaiman Alanazi","doi":"10.18203/2394-6040.ijcmph20241977","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241977","url":null,"abstract":"Public health policies have significantly impacted the reduction of tobacco and substance abuse within communities. Legislative measures, including increased taxation on tobacco products, comprehensive smoking bans, and restrictions on advertising, have been instrumental in decreasing smoking rates and protecting non-smokers from second-hand smoke. Community-based interventions, such as school-based programs and peer-led initiatives, address the root causes of substance abuse by promoting education, social support, and healthy behaviors, tailored to meet the specific needs of local populations, ensuring their relevance and effectiveness. Public awareness campaigns leveraging mass media and educational efforts play a crucial role in changing social norms and attitudes towards tobacco and substance use. Campaigns like the \"truth\" campaign and programs such as life skills training (LST) have shown significant success in reducing smoking and substance use among adolescents and young adults. Integrating these campaigns with other strategies enhances their impact, creating a comprehensive approach to public health. A multifaceted strategy combining legislative action, community engagement, and public education is crucial for achieving sustained reductions in tobacco and substance abuse. Continued investment in these areas is necessary to address evolving challenges and ensure long-term public health benefits. Coordinated efforts involving diverse stakeholders, including policymakers, educators, healthcare providers, and community organizations, are essential for effectively combating tobacco and substance abuse. By fostering collaboration and leveraging local resources, communities can create supportive environments that discourage harmful behaviors and promote healthier lifestyles. These comprehensive strategies demonstrate that a well-rounded approach, incorporating legislative measures, community-based interventions, and public awareness campaigns, is effective in mitigating the prevalence of tobacco and substance abuse, ultimately contributing to improved public health outcomes.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":"125 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141821607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative approaches to microbial identification enhancing accuracy and speed in infectious disease diagnostics","authors":"Khalid Suliman Algrooni, Hanan Mushabab Alhaidan, Huda Abbas Hamzah, Maram Fahad Almarzouqi, Albatol Mohammed Hamad","doi":"10.18203/2394-6040.ijcmph20241966","DOIUrl":"https://doi.org/10.18203/2394-6040.ijcmph20241966","url":null,"abstract":"The rapid and accurate identification of microbial pathogens is crucial for effective management of infectious diseases. Traditional methods, though reliable, are often time-consuming. Recent advancements in molecular diagnostics, mass spectrometry, and next-generation sequencing (NGS) have revolutionized the field by enhancing both the speed and accuracy of microbial identification. Polymerase chain reaction (PCR) and its derivatives, such as real-time PCR, enable rapid amplification of genetic material, significantly reducing diagnostic times. Techniques like nucleic acid sequence-based amplification (NASBA) and loop-mediated isothermal amplification (LAMP) further extend these capabilities to resource-limited settings by operating at constant temperatures. Mass spectrometry, particularly matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF), provides rapid and accurate microbial identification by analyzing protein profiles. This method has high throughput, is cost-effective, and offers the ability to detect antimicrobial resistance, significantly impacting clinical decision-making and patient management. NGS technologies offer comprehensive pathogen detection by sequencing entire microbial genomes. This approach is invaluable in diagnosing complex infections, tracking outbreaks, and identifying antibiotic resistance genes, though its high cost and complexity limit widespread use. The integration of these innovative technologies into clinical practice enhances the ability to diagnose and manage infectious diseases effectively. Molecular diagnostics, mass spectrometry, and NGS each bring unique strengths, from rapid and precise pathogen detection to comprehensive genetic analysis and resistance profiling. These advancements contribute to improved patient outcomes and more effective public health strategies. The continued development and implementation of these technologies are essential to address the evolving challenges in microbial diagnostics, paving the way for more precise and personalized approaches in infectious disease management.","PeriodicalId":502325,"journal":{"name":"International Journal Of Community Medicine And Public Health","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}