Rachel E. Christensen, Isabella Tan, Mohammad Jafferany
{"title":"Recent advances in trichotillomania: a narrative review.","authors":"Rachel E. Christensen, Isabella Tan, Mohammad Jafferany","doi":"10.15570/actaapa.2023.28","DOIUrl":"https://doi.org/10.15570/actaapa.2023.28","url":null,"abstract":"Trichotillomania, defined as the compulsive pulling out of one's hair, is a psychocutaneous condition associated with functional impairment and decreased quality of life. The pathophysiology of trichotillomania is poorly understood and likely multifactorial, involving alterations in both neural activity and cognitive function. Behavioral treatment options for trichotillomania are limited and are often only modestly effective. Moreover, there are no medications currently approved by the U.S. Food and Drug Administration for its treatment. The gaps in knowledge regarding the neurological underpinnings and behavioral markers of trichotillomania and effective treatment options for it highlight the importance of ongoing research in this field. For this narrative review, PubMed was searched to identify articles related to trichotillomania published until July 2023. Recent advances in research on trichotillomania pathophysiology, diagnosis, clinical associations, and treatment are presented, with particular focus on how this condition uniquely spans the disciplines of both psychiatry and dermatology.","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":"86 5","pages":"151-157"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139193692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute onset of leukemia cutis in a 70-year-old-patient: a case report.","authors":"Maruša Selan, N. Stopajnik","doi":"10.15570/actaapa.2023.33","DOIUrl":"https://doi.org/10.15570/actaapa.2023.33","url":null,"abstract":"We report the case of a 70-year-old man with no significant medical history that presented with a rapid onset of generalized pink to livid papules. No enlarged lymph nodes were observed, and laboratory results revealed a low platelet count. A biopsy was performed, and histopathological examination revealed a cutaneous infiltration with a highly malignant blastoid neoplasm. Further examination performed by hematologists, including cytological analysis of a bone marrow puncture, confirmed acute myelogenous leukemia (AML). Molecular genetic testing revealed a mutation in the gene encoding nucleophosmin (NPM1), the most common genetic anomaly in adult AML. He was treated according to protocol with venetoclax and azacitidine, but he died 4 months post-induction due to infectious complications of febrile neutropenia and subsequent sepsis.","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":"34 5-6","pages":"187-189"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Different skin wart types, different human papillomavirus types? A narrative review.","authors":"Lucijan Skubic, V. Breznik, Mario Poljak","doi":"10.15570/actaapa.2023.30","DOIUrl":"https://doi.org/10.15570/actaapa.2023.30","url":null,"abstract":"Skin warts are ubiquitous, self-limiting, benign neoplasms caused by human papillomaviruses (HPV). Several studies have investigated the prevalence and diversity of HPV types in the three main types of skin warts: common, plantar, and flat warts. Using different methodological approaches and diverse populations, several HPV types were detected in skin warts, but often the etiological link remained unconfirmed. This review addresses recently improved multiple strategies for investigating the presence of HPVs in skin warts, covering proper sampling techniques for HPV testing, choice of molecular method(s) for HPV detection, and assignment of the etiological causality of the tested skin wart to a causative HPV type using cellular viral load estimation. These novel approaches provide useful insight into the range of HPV types causing skin warts and support a refined understanding of their etiology. In addition, we conducted a literature review of the main studies examining HPV prevalence and genotype distribution in common warts, plantar warts, and flat warts. Finally, HPV type-specific histopathological patterns in skin warts are briefly discussed.","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":"13 3","pages":"165-171"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139189992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Franulić, E. Parać, Lorena Dolački, Iva Topalušić, L. Lugović-Mihić
{"title":"Cutaneous manifestations of the COVID-19 pandemic in schoolchildren and adolescents.","authors":"Daniela Franulić, E. Parać, Lorena Dolački, Iva Topalušić, L. Lugović-Mihić","doi":"10.15570/actaapa.2023.31","DOIUrl":"https://doi.org/10.15570/actaapa.2023.31","url":null,"abstract":"This review article focuses on cutaneous manifestations in schoolchildren and adolescents 6 to 18 years old connected with various aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, including personal protective equipment (PPE), SARS-CoV-2 infection, and the SARS-CoV-2 vaccine. The use of PPE has been associated with mask-related acne due to microbiome dysbiosis and disruption of skin homeostasis, leading to the emergence of new acne or exacerbation of preexisting acne. Chilblain-like lesions, erythema multiforme-like eruptions, and cutaneous manifestations of multisystem inflammatory syndrome related to SARS-CoV-2 are the most commonly described skin manifestations of SARS-CoV-2 infection. The proposed mechanisms involve either the direct interaction of the virus with the skin through cutaneous receptor angiotensin-converting enzyme 2 in the epidermal basal layer or hyperactive immune responses. The impact of SARS-CoV-2 infection has also been described on adnexa, including hair changes such as alopecia areata and telogen effluvium, as well as nail changes presenting as onychomadesis and periungual desquamation. Cutaneous adverse effects of the SARS-CoV-2 vaccine have been described in case reports and differ from those in adults. Therefore, there is a need for increased awareness regarding the most prevalent cutaneous manifestations associated with COVID-19 in children because they tend to be mild or nonspecific in nature.","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":"10 37","pages":"173-181"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139193981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Špela Baglama, Katarina Trčko, Janez Rebol, Jovan Miljković
{"title":"Oral manifestations of autoinflammatory and autoimmune diseases.","authors":"Špela Baglama, Katarina Trčko, Janez Rebol, Jovan Miljković","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autoimmune diseases may also be reflected in changes in the oral cavity that represent the first sign of the disease, or they may occur simultaneously with or later in the course of the disease. Oral findings are mostly non-specific, and therefore further investigations are needed to exclude or confirm possible diagnoses. This article presents the most important diseases in this research area, divides them into meaningful groups, and highlights the importance of examining the oral cavity for possible manifestations.</p>","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"9-16"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35954621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital atrichia with papular lesions: a rare cause of irreversible childhood alopecia.","authors":"Tasleem Arif, Mohammad Adil, Syed Suhail Amin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Congenital atrichia with papular lesions (APL) is a disease characterized by the complete absence of hair from the whole body occurring within a few months of birth and the presence of papules distributed over the body. A 9-year-old boy presented with sparse hair over his body and with a history of losing his hair soon after birth. Multiple skin-colored papules were observed over the scalp. A biopsy from a papule showed keratinous cysts in the dermis and the absence of hair follicles. A diagnosis of congenital APL was made after vitamin D-dependent rickets was excluded. This case highlights congenital APL as a cause of total alopecia.</p>","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"35-36"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35955104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Fernandes Melo, Violeta Duarte Tortelly, Taynara de Mattos Barreto, Elaine de Souza Albernaz
{"title":"Alopecia areata and salmon patch: an actual association?","authors":"Daniel Fernandes Melo, Violeta Duarte Tortelly, Taynara de Mattos Barreto, Elaine de Souza Albernaz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"49-50"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35955112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends in the epidemiology of erysipelas in Slovenia.","authors":"Katarina Sočan, Maja Sočan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Erysipelas is a common infection of the skin and subcutaneous tissue. Despite the relative frequency of erysipelas, data on its basic epidemiological characteristics are scant. This study describes the trends in erysipelas epidemiology in Slovenia.</p><p><strong>Methods: </strong>Data on notified erysipelas cases from 2000 to 2016 were extracted from the electronic database of reportable communicable diseases and analyzed.</p><p><strong>Results: </strong>There were 36,254 notified cases during the observed time period of 17 years. The yearly age-standardized incidence rate of erysipelas increased from 71.5 per 100,000 in 2000 to 111.3 per 100,000 in 2016, with the main rise in the ≥ 75 age group. Erysipelas was more common in women, but the sex-related difference lessened in the period observed. The hospitalization rate declined. Erysipelas was significantly more frequent in the warmer period of the year. The correlation between erysipelas incidence and average monthly temperature was stronger in the ≤ 64 age group than in the ≥ 65 age group.</p><p><strong>Conclusions: </strong>Retrospective observational data confirmed a rising trend in erysipelas cases, especially among the elderly. Aging of the population will continue to increase the burden of the disease, unless health promotion and prevention lowers the prevalence of the risk factors.</p>","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"1-4"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35954017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fat and MEAT. A rare benign lesion of adipose tissue.","authors":"Uwe Wollina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concept of mobile tumors was introduced by Shelley and Shelley in 2006. They coined the term abacus tumor. Mobile lipomas have been described in the literature as an example of abacus tumors. This was later questioned by Burgdorf et al., who performed comparative studies in cattle. They suggested the term mobile encapsulated adipose tissue (MEAT) for lipoma-like mobile lesions in cattle and people. We report two more cases of MEAT in adult patients and discuss the literature on this unusual subject.</p>","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"41-43"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35955106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inflamed bilateral linear atrophoderma of Moulin in an adult woman: a case report.","authors":"Yesim Akpinar Kara, Evren Sarifakioglu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Linear atrophoderma of Moulin (LAM) is a rare dermatosis characterized by a hyperpigmented atrophoderma that follows Blaschko's lines, with onset usually occurring during childhood and adolescence. LAM is an etiologically unknown form of dermal atrophy. It is generally characterized by oval or round atrophic, nonsclerotic, hyperpigmented patches following Blaschko's lines. These patches are usually located on the trunk and the upper and lower extremities. This case study discusses a patient that had the nonclassical form of LAM with the initial lesions presenting as papules.</p>","PeriodicalId":502234,"journal":{"name":"Acta dermatovenerologica Alpina, Pannonica, et Adriatica","volume":" ","pages":"29-31"},"PeriodicalIF":1.2,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35954623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}