Chemosensors最新文献_第2页

SERS Substrate Based on Ag Nanoparticles@Layered Double Hydroxide@graphene Oxide and Au@Ag Core–Shell Nanoparticles for Detection of Two Taste and Odor Compounds 基于银纳米颗粒@层状双氢氧化物@氧化石墨烯和 Au@Ag 核壳纳米颗粒的 SERS 基底用于检测两种味道和气味化合物

Chemosensors Pub Date : 2024-07-11 DOI: 10.3390/chemosensors12070137

Zhixiong Lao, Mingmin Zhong, Yin Liang, Jianrong Tan, Xiaoyan Liang, Wucheng Xie, Yong Liang, Jun Wang

{"title":"SERS Substrate Based on Ag Nanoparticles@Layered Double Hydroxide@graphene Oxide and Au@Ag Core–Shell Nanoparticles for Detection of Two Taste and Odor Compounds","authors":"Zhixiong Lao, Mingmin Zhong, Yin Liang, Jianrong Tan, Xiaoyan Liang, Wucheng Xie, Yong Liang, Jun Wang","doi":"10.3390/chemosensors12070137","DOIUrl":"https://doi.org/10.3390/chemosensors12070137","url":null,"abstract":"Sulfide organics and phenols are ubiquitous in freshwater lakes all over the world. As two taste and odor (T and O) compounds, they are harmful to the environment and human body. The existing detection methods for T and O compounds mainly include sensory analysis and gas-phase mass spectrometry, which are cumbersome and time-consuming. Herein, a method for the simultaneous and rapid detection of two T and O compounds (methyl sulfide and 2,4-di-tert-butylphenol) based on surface-enhanced Raman spectroscopy (SERS) is firstly developed. The SERS substrate was prepared by coating Ag nanoparticles (Ag NPs), layered double hydroxide (LDH), and graphene oxide (GO) on the surface of an Ag-coated Au nanoparticle (Au@Ag NP) substrate. Under optimal conditions, this SERS substrate possessed low detection limits of 1.53 ppm for methyl sulfide and 0.39 ppm for 2,4-di-tert-butylphenol. In addition, it took only 20 min to complete the detection using this method, without complex sample pretreatment. Furthermore, it was successfully applied to simultaneously detect methyl sulfide and 2,4-di-tert-butylphenol in actual water samples and had good application prospects for the rapid detection of T and O compounds in water.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":"55 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141655669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Understanding of the Surface-Enhanced Raman Spectroscopy Salivary Fingerprint in People after Sars-COV-2 Infection and in Vaccinated Subjects 表面增强拉曼光谱对感染 Sars-COV-2 病毒和接种疫苗者唾液指纹的分子认识

Chemosensors Pub Date : 2024-07-11 DOI: 10.3390/chemosensors12070136

Francesca Rodà, A. Gualerzi, S. Picciolini, Luana Forleo, Valentina Mangolini, Roberta Mancuso, S. Agostini, Rudy Alexander Rossetto, Paola Pierucci, Paolo Banfi, M. Bedoni

{"title":"Molecular Understanding of the Surface-Enhanced Raman Spectroscopy Salivary Fingerprint in People after Sars-COV-2 Infection and in Vaccinated Subjects","authors":"Francesca Rodà, A. Gualerzi, S. Picciolini, Luana Forleo, Valentina Mangolini, Roberta Mancuso, S. Agostini, Rudy Alexander Rossetto, Paola Pierucci, Paolo Banfi, M. Bedoni","doi":"10.3390/chemosensors12070136","DOIUrl":"https://doi.org/10.3390/chemosensors12070136","url":null,"abstract":"The rapid spread of SARS-COV-2 and the millions of worldwide deaths and hospitalizations have prompted an urgent need for the development of screening tests capable of rapidly and accurately detecting the virus, even in asymptomatic people. The easy collection and the biomarker content of saliva, together with the label-free and informative power of surface-enhanced Raman spectroscopy (SERS) analysis have driven the creation of point-of-care platforms capable of identifying people with COVID-19. Indeed, different salivary fingerprints were observed between uninfected and infected people. Hence, we performed a retrospective analysis of SERS spectra from salivary samples of COVID-19-infected and -vaccinated subjects to understand if viral components and/or the immune response are implicated in spectral variations. The high sensitivity of the proposed SERS-based method highlighted the persistence of molecular alterations in saliva up to one month after the first positive swab, even when the subject tested negative for the rapid antigenic test. Nevertheless, no specific spectral patterns attributable to some viral proteins and immunoglobulins involved in COVID-19 infection and its progression were found, even if differences in peak intensity, presence, and position were observed in the salivary SERS fingerprint.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":"91 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in the Application of Metal–Organic Frameworks and Coordination Polymers in Electrochemical Biosensors 在电化学生物传感器中应用金属有机框架和配位聚合物的最新进展

Chemosensors Pub Date : 2024-07-09 DOI: 10.3390/chemosensors12070135

Alemayehu Kidanemariam, Sungbo Cho

{"title":"Recent Advances in the Application of Metal–Organic Frameworks and Coordination Polymers in Electrochemical Biosensors","authors":"Alemayehu Kidanemariam, Sungbo Cho","doi":"10.3390/chemosensors12070135","DOIUrl":"https://doi.org/10.3390/chemosensors12070135","url":null,"abstract":"Electrochemical biosensors are critical in advancing biomedical and pharmaceutical therapies because of their adaptability and cost-effectiveness. Voltammetric and amperometric sensors are of particular interest. These sensors typically consist of a specialized tip or biorecognition element and a transducer that converts biological data into readable signals. Efficient biosensor materials are essential for addressing health emergencies, with coordination polymers (CPs) and metal–organic frameworks (MOFs) showing promise. Functionalization strategies are necessary to enhance the usability of pristine MOFs, owing to issues such as low conductivity. The integration of conductive polymers with MOFs has resulted in the development of highly efficient biosensors. Both enzymatic and nonenzymatic biosensors are used for analyte detection; nonenzymatic approaches are gaining popularity owing to their durability and accuracy. MOFs and CPs have been applied in sensitive electrochemical biosensors to detect fatal brain tumors such as glioblastomas (GBM). These biosensors demonstrate enhanced selectivity and sensitivity, highlighting the potential of MOFs and CPs in advancing electrochemical biosensor technology for both in vivo and in vitro applications.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":"105 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of a Headspace Gas Chromatography with Flame Ionization Detection Method to Quantify Blood Alcohol Concentration (BAC) for Forensic Practice 顶空气相色谱火焰离子化检测法对法医实践中血液酒精浓度（BAC）定量方法的验证

Chemosensors Pub Date : 2024-07-09 DOI: 10.3390/chemosensors12070133

Alice Cerioni, Gianmario Mietti, M. Cippitelli, Giulia Ricchezze, Erika Buratti, R. Froldi, Mariano Cingolani, R. Scendoni

引用次数: 0

Enhancement of Ion-Sensitive Field-Effect Transistors through Sol-Gel Processed Lead Zirconate Titanate Ferroelectric Film Integration and Coplanar Gate Sensing Paradigm 通过溶胶-凝胶法锆钛酸铅铁电薄膜集成和共面栅极传感范例增强离子敏感场效应晶体管的性能

Chemosensors Pub Date : 2024-07-09 DOI: 10.3390/chemosensors12070134

Dong-Gyun Mah, Seong-Moo Oh, Jongwan Jung, Won-Ju Cho

{"title":"Enhancement of Ion-Sensitive Field-Effect Transistors through Sol-Gel Processed Lead Zirconate Titanate Ferroelectric Film Integration and Coplanar Gate Sensing Paradigm","authors":"Dong-Gyun Mah, Seong-Moo Oh, Jongwan Jung, Won-Ju Cho","doi":"10.3390/chemosensors12070134","DOIUrl":"https://doi.org/10.3390/chemosensors12070134","url":null,"abstract":"To facilitate the utility of field effect transistor (FET)-type sensors, achieving sensitivity enhancement beyond the Nernst limit is crucial. Thus, this study proposed a novel approach for the development of ferroelectric FETs (FeFETs) using lead zirconate titanate (PZT) ferroelectric films integrated with indium–tungsten oxide (IWO) channels synthesized via a cost-effective sol-gel process. The electrical properties of PZT-IWO FeFET devices were significantly enhanced through the strategic implementation of PZT film treatment by employing intentional annealing procedures. Consequently, key performance metrics, including the transfer curve on/off ratio and subthreshold swings, were improved. Moreover, unprecedented electrical stability was realized by eliminating the hysteresis effect during double sweeps. By leveraging a single-gate configuration as an FeFET transformation element, extended-gate (EG) detection methodologies for pH sensing were explored, thereby introducing a pioneering dimension to sensor architecture. A measurement paradigm inspired by plane gate work was adopted, and the proposed device exhibited significant resistive coupling, consequently surpassing the sensitivity thresholds of conventional ion-sensitive field-effect transistors. This achievement represents a substantial paradigm shift in the landscape of ion-sensing methodologies, surpassing the established Nernst limit (59.14 mV/pH). Furthermore, this study advances FeFET technology and paves the way for the realization of highly sensitive and reliable ion sensing modalities.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141664293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rapid and Interference-Resistant Formaldehyde Detection Method Based on Surface-Enhanced Raman Spectroscopy with A Reaction-Induced Self-Amplification Strategy 基于表面增强拉曼光谱和反应诱导自放大策略的快速抗干扰甲醛检测方法

Chemosensors Pub Date : 2024-07-08 DOI: 10.3390/chemosensors12070132

Chen Wang, Yanli Gao, Xinrong Qiu, Lifang Nie, Yang Liu, Rigui Zhou, Hongpeng Wang, Shengjun Xiong

{"title":"A Rapid and Interference-Resistant Formaldehyde Detection Method Based on Surface-Enhanced Raman Spectroscopy with A Reaction-Induced Self-Amplification Strategy","authors":"Chen Wang, Yanli Gao, Xinrong Qiu, Lifang Nie, Yang Liu, Rigui Zhou, Hongpeng Wang, Shengjun Xiong","doi":"10.3390/chemosensors12070132","DOIUrl":"https://doi.org/10.3390/chemosensors12070132","url":null,"abstract":"Formaldehyde is widely utilized across various industries such as food, textiles, and leather, yet its presence raises significant health concerns due to its irritation and carcinogenicity. Numerous methods have been developed to probe it in solution and gas states. Among them, absorption spectroscopy-based methods commonly employed. However, these methods require complex preprocessing for colored solutions to avoid interference. In response to this challenge, a novel interference-resistant detection kit leveraging surface-enhanced Raman spectroscopy (SERS) coupled with reaction-induced self-amplification for rapid and direct detection of formaldehyde was developed. The kit needed only ten minutes and achieved a limit of detection lower than 10−4 μg/mL with a handheld Raman spectrometer. Thanks to the kit’s reaction with formaldehyde, colloidal nanoparticles were linked to form “hot-spots” to further enhance the SERS signals. The signal demonstrated outstanding resistance to interference, including different dyes, ensuring a practical tool for direct detection of formaldehyde in complex solutions.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":"118 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling Hidden Insights in Gas Chromatography Data Analysis with Generative Adversarial Networks 利用生成式对抗网络揭示气相色谱数据分析中的隐藏见解

Chemosensors Pub Date : 2024-07-07 DOI: 10.3390/chemosensors12070131

Namkyung Yoon, Wooyong Jung, Hwangnam Kim

{"title":"Unveiling Hidden Insights in Gas Chromatography Data Analysis with Generative Adversarial Networks","authors":"Namkyung Yoon, Wooyong Jung, Hwangnam Kim","doi":"10.3390/chemosensors12070131","DOIUrl":"https://doi.org/10.3390/chemosensors12070131","url":null,"abstract":"The gas chromatography analysis method for chemical substances enables accurate analysis to precisely distinguish the components of a mixture. This paper presents a technique for augmenting time-series data of chemicals measured by gas chromatography instruments with artificial intelligence techniques such as generative adversarial networks (GAN). We propose a novel GAN algorithm called GCGAN for gas chromatography data, a unified model of autoencoder (AE) and GAN for effective time-series data learning with an attention mechanism. The proposed GCGAN utilizes AE to learn a limited number of data more effectively. We also build a layer of high-performance generative adversarial neural networks based on the analysis of the features of data measured by gas chromatography instruments. Then, based on the proposed learning, we synthesize the features embedded in the gas chromatography data into a feature distribution that extracts the temporal variability. GCGAN synthesizes the features embedded in the gas chromatography data into a feature distribution that extracts the temporal variability of the data over time. We have fully implemented the proposed GCGAN and experimentally verified that the data augmented by the GCGAN have the characteristic properties of the original gas chromatography data. The augmented data demonstrate high quality with the Pearson correlation coefficient, Spearman correlation coefficient, and cosine similarity all exceeding 0.9, significantly enhancing the performance of AI classification models by 40%. This research can be effectively applied to various small dataset domains other than gas chromatography data, where data samples are limited and difficult to obtain.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141671223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profiling of Organosulfur Compounds in Onions: A Comparative Study between LC-HRMS and DTD-GC-MS 洋葱中有机硫化合物的分析：LC-HRMS 与 DTD-GC-MS 的比较研究

Chemosensors Pub Date : 2024-07-06 DOI: 10.3390/chemosensors12070130

A. V. González-de-Peredo, Alicia Maroto, G. F. Barbero, A. Memboeuf

{"title":"Profiling of Organosulfur Compounds in Onions: A Comparative Study between LC-HRMS and DTD-GC-MS","authors":"A. V. González-de-Peredo, Alicia Maroto, G. F. Barbero, A. Memboeuf","doi":"10.3390/chemosensors12070130","DOIUrl":"https://doi.org/10.3390/chemosensors12070130","url":null,"abstract":"Onions are known not only for their culinary importance but also for their nutritional and health-promoting properties. Both properties are closely linked to their content of organosulfur compounds, which account for up to 5% of the dry weight of an onion. Given the importance of these compounds, suitable analytical methods are required for their study. Two techniques should be highlighted in this context: gas chromatography coupled to mass spectrometry (GC-MS), and liquid chromatography coupled to mass spectrometry (LC-MS). In this study, eight different onion varieties were analyzed using two distinct analytical techniques: direct thermal desorption–gas chromatography–mass spectrometry (DTD-GC-MS) and high-resolution mass spectrometry (HRMS) on an LC-ESI-QqTOF instrument. Each method identified different organosulfur compounds, with LC-HRMS targeting 15 non-volatile compounds, such as cysteine sulfoxides, and GC-MS targeting 18 volatiles, such as disulfides and trisulfides. The results obtained were studied using Pearson correlations and principal component analysis. No precise correlation was found between the initial organosulfur compounds in onions and their hydrolysates. Consequently, although GC is one of the most employed techniques in the scientific literature, the use of LC-HRMS or a combination of both techniques may offer a more comprehensive and accurate description of the metabolomic profile of onions.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141673143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Development of Electrospun Nanostructured Fibers as Colorimetric Probes for Metal Ion Sensing: A Review 作为金属离子传感比色探针的电纺纳米结构纤维的最新发展：综述

Chemosensors Pub Date : 2024-07-05 DOI: 10.3390/chemosensors12070129

Mohanraj Jagannathan, Ravi Kumar Yohan, Sungbo Cho

{"title":"Recent Development of Electrospun Nanostructured Fibers as Colorimetric Probes for Metal Ion Sensing: A Review","authors":"Mohanraj Jagannathan, Ravi Kumar Yohan, Sungbo Cho","doi":"10.3390/chemosensors12070129","DOIUrl":"https://doi.org/10.3390/chemosensors12070129","url":null,"abstract":"The colorimetric detection of metal ions has witnessed a surge in advancements, with nanostructured fibers emerging as a powerful platform for environmental monitoring and remediation applications. These fibers offer several advantages, including a high surface area, enhanced sensitivity and selectivity, non-intrusive analysis, rapid response times, robustness under harsh conditions, and user-friendly handling. This unique combination makes them particularly suitable for visible eye detection of metal ions in remote or challenging environments. This review provides a concise overview of recent developments in nanostructured fibers, and their cutting-edge fabrication methods, for the colorimetric-based detection of various heavy metal ions in real-time samples. By exploiting the unique properties of these fibers, colorimetric detection offers a promising and cost-effective approach for heavy metal ion determination. This review delves into the design principles, functionalization strategies, and detection mechanisms employed in these innovative sensors. We highlight the potential of nanostructured fibers as a well-established and efficient platform for the colorimetric detection of heavy metals, paving the way for more sustainable and accessible environmental monitoring solutions.","PeriodicalId":502217,"journal":{"name":"Chemosensors","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141676595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on the Detection of Hg(II) in Seawater Using GR-MWCNTs/CeO2-Modified Electrodes 利用 GR-MWCNTs/CeO2 改性电极检测海水中 Hg(II) 的研究

Chemosensors Pub Date : 2024-07-04 DOI: 10.3390/chemosensors12070128

Huili Hao, Chengjun Qiu, Wei Qu, Zhuang Yuan, Xiaochun Han, Wei Tao, Yang Gu, Zizi Zhao, Haozheng Liu, Wenhao Wang

引用次数: 0