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Evaluating Well-being of Individuals With Chronic Visual Conditions Requiring Regular Eyecare During COVID-19 Lockdown: A Cross-Sectional Study. 评估在COVID-19封锁期间需要定期眼部护理的慢性视力疾病患者的健康状况:一项横断面研究。
IF 2.3
Eye & Contact Lens Pub Date : 2021-10-01 DOI: 10.1097/ICL.0000000000000834
Khader A Almhdawi, Munsif Fayiz Alsalem, Donia Obeidat, Laith T Al-Khateeb, Mohammad Nayef Al Aqarbah, Wejdan Mahmoud Alshiyab, Alaa Adeeb Arabiat, Mohammed Abdullah Bazel, Zaidoon Al-Share
{"title":"Evaluating Well-being of Individuals With Chronic Visual Conditions Requiring Regular Eyecare During COVID-19 Lockdown: A Cross-Sectional Study.","authors":"Khader A Almhdawi,&nbsp;Munsif Fayiz Alsalem,&nbsp;Donia Obeidat,&nbsp;Laith T Al-Khateeb,&nbsp;Mohammad Nayef Al Aqarbah,&nbsp;Wejdan Mahmoud Alshiyab,&nbsp;Alaa Adeeb Arabiat,&nbsp;Mohammed Abdullah Bazel,&nbsp;Zaidoon Al-Share","doi":"10.1097/ICL.0000000000000834","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000834","url":null,"abstract":"<p><strong>Objectives: </strong>To assess health-related quality of life (HRQoL) and its predictors among individuals with chronic vision conditions during COVID-19 lockdown.</p><p><strong>Methods: </strong>A cross-sectional, survey-based study targeted Jordanian adults with a variety of chronic vision conditions requiring regular ophthalmic follow-up. Outcome measures included HRQoL measured by the 12-item Short-Form Health Survey (SF-12), mental health symptoms measured by the Depression Anxiety Stress Scale, and vision ability measured by the National Eye Institute Visual Functioning Questionnaire (VFQ-25) General Vision and Role Limitation subscales. Data were analyzed descriptively and using a multiple variable linear regression model to identify HRQoL predictors.</p><p><strong>Results: </strong>A total of 203 participants with a mean age of 52.09 (±15.41) years participated, and SF-12 mean scores were 58.15 for the physical component and 57.48 for the mental component. The level of HRQoL was significantly associated with VFQ-25 Role Limitation subscale, diabetes, the need of ophthalmic follow-up, and stress. The regression model explained 47.1% of the variance in HRQoL (r2=0.471, F=35.57, P<0.001).</p><p><strong>Conclusions: </strong>Jordanian individuals with chronic vision conditions demonstrated low levels of HRQoL during COVID-19 lockdown. Participants also showed high levels of mental health symptoms and reported low accessibility to ophthalmic care. Access to nonurgent ophthalmic care in individuals with chronic vision diseases should be carefully planned in future pandemics.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"559-564"},"PeriodicalIF":2.3,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39432022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Identifying Eyes That Can Benefit From Cross-linking Is Mostly a Question of Clinical Judgment. 识别可以从交联中受益的眼睛主要是一个临床判断问题。
IF 2.3
Eye & Contact Lens Pub Date : 2021-09-01 DOI: 10.1097/ICL.0000000000000826
Carina Koppen
{"title":"Identifying Eyes That Can Benefit From Cross-linking Is Mostly a Question of Clinical Judgment.","authors":"Carina Koppen","doi":"10.1097/ICL.0000000000000826","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000826","url":null,"abstract":"","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"485"},"PeriodicalIF":2.3,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39349977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Erratum: Relation Between Body Mass Index and Dry Eye Disease: The Japan Public Health Center-Based Prospective Study for the Next Generation. 勘误:身体质量指数和干眼病之间的关系:日本公共卫生中心为下一代开展的前瞻性研究。
IF 2.3
Eye & Contact Lens Pub Date : 2021-09-01 DOI: 10.1097/ICL.0000000000000838
{"title":"Erratum: Relation Between Body Mass Index and Dry Eye Disease: The Japan Public Health Center-Based Prospective Study for the Next Generation.","authors":"","doi":"10.1097/ICL.0000000000000838","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000838","url":null,"abstract":"","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"532"},"PeriodicalIF":2.3,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39349979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Characteristics and Risk Factors of Very Asymmetric Keratoconus. 非常不对称圆锥角膜的特点及危险因素分析。
IF 2.3
Eye & Contact Lens Pub Date : 2021-09-01 DOI: 10.1097/ICL.0000000000000830
Gen Nakao, Shizuka Koh, Ryota Inoue, Sayo Maeno, Naoyuki Maeda, Kohji Nishida
{"title":"The Characteristics and Risk Factors of Very Asymmetric Keratoconus.","authors":"Gen Nakao,&nbsp;Shizuka Koh,&nbsp;Ryota Inoue,&nbsp;Sayo Maeno,&nbsp;Naoyuki Maeda,&nbsp;Kohji Nishida","doi":"10.1097/ICL.0000000000000830","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000830","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize very asymmetric keratoconus (KC) in terms of clinical demographics and risk factors in the Japanese population.</p><p><strong>Methods: </strong>We retrospectively reviewed the clinical records of patients with very asymmetric KC attending a university hospital. Patients with very asymmetric KC had defined clinical KC in one eye and normal topography in the fellow eye. All patients completed a questionnaire on potential risk factors (family history of KC, atopy, asthma, allergy, heart disease, sleep apnea, Down syndrome, eye rubbing, prone sleep position, and dominant hand). These data were compared with those of patients with clinical or topographic KC in both eyes. Subgroup analysis of very asymmetric KC eyes were performed based on the KC status: mild and severe.</p><p><strong>Results: </strong>We retrospectively investigated 66 patients with very asymmetric KC and 505 patients with KC. Patients reported eye rubbing (53%-56%), allergy (62%-63%), and atopy (28%-29%) in both groups. There was no significant difference in terms of risk factors between the two groups. Approximately half of the 66 patients with very asymmetric KC had KC eyes ipsilateral to the dominant hand. Subgroup analysis of very asymmetric KC showed that atopy and asthma were more frequent in the mild KC group than in the severe KC group. Forty-four of 60 patients (73.3%) were using corneal, rigid, gas-permeable contact lenses (corneal GPs) for the KC eye, of which 30 patients (68.2%) were also using a corneal GP for the fellow eye.</p><p><strong>Conclusions: </strong>The patient-reported frequency of eye rubbing, allergy, and atopy were similar between KC and very asymmetric KC. Furthermore, we found no association between hand dominance and KC laterality.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"511-514"},"PeriodicalIF":2.3,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39349978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Diagnoses and Outcomes of Prosthetic Replacement of the Ocular Surface Ecosystem Treatment-A Canadian Experience. 假体置换术治疗眼表生态系统的诊断和结果-加拿大经验。
IF 2.3
Eye & Contact Lens Pub Date : 2021-07-01 DOI: 10.1097/ICL.0000000000000779
Bryan M Wong, Anubhav Garg, Tanya Trinh, Michael Mimouni, Stephanie Ramdass, Jennifer Liao, Manokaraananthan Chandrakumar, Clara C Chan, Allan R Slomovic
{"title":"Diagnoses and Outcomes of Prosthetic Replacement of the Ocular Surface Ecosystem Treatment-A Canadian Experience.","authors":"Bryan M Wong,&nbsp;Anubhav Garg,&nbsp;Tanya Trinh,&nbsp;Michael Mimouni,&nbsp;Stephanie Ramdass,&nbsp;Jennifer Liao,&nbsp;Manokaraananthan Chandrakumar,&nbsp;Clara C Chan,&nbsp;Allan R Slomovic","doi":"10.1097/ICL.0000000000000779","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000779","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate underlying diagnoses and outcomes of patients undergoing Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment at the first Canadian PROSE center.</p><p><strong>Methods: </strong>A retrospective chart review was conducted on patients referred for PROSE treatment and fitted with PROSE devices from 2018 to 2020. Data were collected on diagnoses, presenting symptoms, previous lens modalities attempted, best-corrected visual acuities (BCVAs) pre-PROSE and post-PROSE, daily wear time, and failure rates. Best-corrected visual acuities pre-PROSE and post-PROSE were compared to evaluate visual improvement.</p><p><strong>Results: </strong>In total, 78 patients (126 eyes) were analyzed. The most common diagnoses were keratoconus (n=39 eyes) and postcorneal graft (n=15) in the distorted cornea group, and limbal stem cell deficiency (n=17) and graft versus host disease (n=15) in the ocular surface disease (OSD) group. Most frequent symptoms included blur, photophobia, and pain. Most common lens modalities attempted pre-PROSE were conventional scleral lenses and glasses. The overall mean BCVA improvement was 0.40 logarithm of the minimal angle of resolution (logMAR) (4-lines Snellen) (P<0.0001). Best-corrected visual acuities improvement in the distorted cornea group (0.52 logMAR, 5-lines) was significantly greater than in the OSD group (0.29 logMAR, 3-lines) (P=0.004).</p><p><strong>Conclusions: </strong>Prosthetic replacement of the ocular surface ecosystem treatment can provide significant visual improvement for patients with distorted corneal surfaces and OSDs who failed other lens modalities.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"394-400"},"PeriodicalIF":2.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25532922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Progression From Soft Lens to Piggyback Soft-Scleral Contact Lens System to Facilitate Scleral Lens Use in a Pediatric Patient. 从软晶状体到背负式软巩膜接触镜系统的发展以促进儿童患者巩膜晶状体的使用。
IF 2.3
Eye & Contact Lens Pub Date : 2021-07-01 DOI: 10.1097/ICL.0000000000000776
David A Murphy, Jeffrey S Samples, Emily M Zepeda, Kamran M Riaz
{"title":"Progression From Soft Lens to Piggyback Soft-Scleral Contact Lens System to Facilitate Scleral Lens Use in a Pediatric Patient.","authors":"David A Murphy,&nbsp;Jeffrey S Samples,&nbsp;Emily M Zepeda,&nbsp;Kamran M Riaz","doi":"10.1097/ICL.0000000000000776","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000776","url":null,"abstract":"<p><strong>Abstract: </strong>Traumatic injury in the pediatric population often results in significant refractive errors that if left untreated can lead to amblyopia. Scleral contact lenses (ScCLs) have recently gained popularity in this population for efficacy in treatment of significant refractive errors, including irregularity astigmatism and corneal abnormalities. Scleral contact lens intolerance may limit the ability of practitioners to use this modality. Although a soft contact lens (SCL) is generally well tolerated, it cannot treat refractive error as effectively as an ScCL. We recently used an SCL followed by an SCL-ScCL combination (\"piggyback\" system) sequence in a pediatric patient to facilitate use of an ScCL alone. We hope that our results may provide practitioners with an additional option when treating this challenging patient population.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"426-428"},"PeriodicalIF":2.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25389097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Corneal Changes After Belantamab Mafodotin in Multiple Myeloma Patients. 多发性骨髓瘤患者贝兰他单抗治疗后角膜的变化。
IF 2.3
Eye & Contact Lens Pub Date : 2021-06-01 DOI: 10.1097/ICL.0000000000000768
Rebecca B Bausell, Arshia Soleimani, Alfred Vinnett, Mariana D Baroni, Sheila A Staub, Katrina Binion, Bennie H Jeng, Ashraf Z Badros, Wuqaas M Munir
{"title":"Corneal Changes After Belantamab Mafodotin in Multiple Myeloma Patients.","authors":"Rebecca B Bausell,&nbsp;Arshia Soleimani,&nbsp;Alfred Vinnett,&nbsp;Mariana D Baroni,&nbsp;Sheila A Staub,&nbsp;Katrina Binion,&nbsp;Bennie H Jeng,&nbsp;Ashraf Z Badros,&nbsp;Wuqaas M Munir","doi":"10.1097/ICL.0000000000000768","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000768","url":null,"abstract":"Objectives: To describe progressive corneal microcyst-like epithelial changes (MECs) that developed in patients treated with the investigational drug belantamab mafodotin (belamaf) for refractory multiple myeloma (MM). Methods: This is a single center case series of patients with MM receiving the investigational drug belamaf. Results: All 12 patients included in this analysis who were treated with belamaf developed MECs that initially appeared in the peripheral cornea and progressed centrally with time. Cessation of therapy resulted in regression of the MECs first in the periphery then centrally. Microcyst-like epithelial changes recurred in all patients on retreatment. With prolonged therapy, eight patients developed corneal staining patterns suggestive of limbal stem cell dysfunction (LSCD). Conclusion: We describe MECs and LSCD associated with systemic administration of belamaf. Further study is needed to determine the etiology and composition of the MECs and the mechanism of limbal stem cell involvement.","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"362-365"},"PeriodicalIF":2.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38703107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Effects of a Single Dose of Topical Brimonidine 0.15% on Anterior Segment Morphology, Pupil Characteristics, and Choroidal Thickness in Healthy Subjects. 单剂量0.15%的外用溴莫尼定对健康受试者前节形态、瞳孔特征和脉络膜厚度的影响
IF 2.3
Eye & Contact Lens Pub Date : 2021-06-01 DOI: 10.1097/ICL.0000000000000708
Veysel Cankurtaran, Kemal Tekin
{"title":"Effects of a Single Dose of Topical Brimonidine 0.15% on Anterior Segment Morphology, Pupil Characteristics, and Choroidal Thickness in Healthy Subjects.","authors":"Veysel Cankurtaran,&nbsp;Kemal Tekin","doi":"10.1097/ICL.0000000000000708","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000708","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effects of a single dose of brimonidine 0.15% on anterior segment morphology, pupil characteristics, and choroidal blood flow in treated and untreated eyes of healthy subjects and to compare the results obtained with those in another healthy volunteer group.</p><p><strong>Methods: </strong>Participants were classified as study and control groups. The eyes in the study group were randomized. Only one eye received one drop of brimonidine (treated eyes), and the contralateral eye received single dose of sodium hyaluronate (untreated eyes). In addition, only right eyes of control subjects, who had single dose of sodium hyaluronate to both eyes, were analyzed (control eyes). Anterior segment parameters including central corneal thickness (CCT), aqueous depth, anterior chamber volume, iridocorneal angle (ICA), horizontal anterior chamber diameter, and pupil measurements including scotopic, mesopic, photopic, and dynamic pupil diameters (PDs) were performed with Sirius Scheimpflug camera. Choroidal thickness (CT) measurements were taken with optical coherence tomography. These measurements were taken at baseline and repeated 1 hour after the dosing.</p><p><strong>Results: </strong>Only the treated eyes had significantly thicker CCT and wider ICA values after instillation of brimonidine. Static and dynamic PD values of treated eyes and even untreated eyes significantly decreased after brimonidine. However, brimonidine has no significant effect on CT measurements.</p><p><strong>Conclusion: </strong>A single dose of brimonidine causes thickening in CCT and widening in ICA values in treated eyes. In addition, it has significant effect to decrease the scotopic, mesopic, photopic, and dynamic PD values in treated and even contralateral eyes while has no effect on choroidal blood flow.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"323-329"},"PeriodicalIF":2.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37966891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Optimization of Contact Lenses for Corneal Protection During Vitreoretinal Surgery. 玻璃体视网膜手术中角膜保护隐形眼镜的优化。
IF 2.3
Eye & Contact Lens Pub Date : 2021-06-01 DOI: 10.1097/ICL.0000000000000764
Shan Sang, Jinxin Miao, Zizhong Hu, Songtao Yuan, Ping Xie, Qinghuai Liu
{"title":"Optimization of Contact Lenses for Corneal Protection During Vitreoretinal Surgery.","authors":"Shan Sang,&nbsp;Jinxin Miao,&nbsp;Zizhong Hu,&nbsp;Songtao Yuan,&nbsp;Ping Xie,&nbsp;Qinghuai Liu","doi":"10.1097/ICL.0000000000000764","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000764","url":null,"abstract":"<p><strong>Objectives: </strong>To optimize parameters of contact lenses (CLs) and evaluate their ability to protect the cornea during vitreoretinal surgery.</p><p><strong>Methods: </strong>We compared the protective effects of balanced saline solution, viscoelastic agent, and CLs on rabbit corneas under conditions simulating vitreoretinal surgery. We evaluated CLs of different thicknesses and compared the protective effects of polymethyl methacrylate (PMMA) and gas-permeable fluorosilicone acrylate (XO) lenses on the corneas of rabbits and patients with severe proliferative diabetic retinopathy (PDR). The corneal fluorescein staining score (FSS) was measured to compare the protective effects of CLs.</p><p><strong>Results: </strong>The FSS was significantly lower in the PMMA group than in the balanced saline solution and viscoelastic agent groups. The thickness of the PMMA lenses had no significant effect on the FSS. The FSS was significantly higher in the PMMA group than in the XO group. In patients with PDR, on day 1 after vitreoretinal surgery, the FSS was significantly higher in the PMMA group than in the XO group, although no significant difference was observed on postoperative day 7.</p><p><strong>Conclusion: </strong>The XO lens offers better corneal protection during noncontact wide-angle vitreoretinal surgery and protects the corneal epithelium more efficiently during vitrectomy in patients with PDR, irrespective of its thickness.</p>","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"356-361"},"PeriodicalIF":2.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38706970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Sodium Hyaluronate Concentration in Tear Meniscus Height: 10-min Dynamic Profile After Single Instillation. 透明质酸钠浓度对撕裂半月板高度的影响:单次注射后10min动态剖面。
IF 2.3
Eye & Contact Lens Pub Date : 2021-06-01 DOI: 10.1097/ICL.0000000000000733
Carlos Rocha-de-Lossada, José-María Sánchez-González, Francisco Zamorano-Martín, Rahul Rachwani-Anil, Josep Torras-Sanvicens, Jorge Peraza-Nieves
{"title":"Influence of Sodium Hyaluronate Concentration in Tear Meniscus Height: 10-min Dynamic Profile After Single Instillation.","authors":"Carlos Rocha-de-Lossada,&nbsp;José-María Sánchez-González,&nbsp;Francisco Zamorano-Martín,&nbsp;Rahul Rachwani-Anil,&nbsp;Josep Torras-Sanvicens,&nbsp;Jorge Peraza-Nieves","doi":"10.1097/ICL.0000000000000733","DOIUrl":"https://doi.org/10.1097/ICL.0000000000000733","url":null,"abstract":"Purpose: To assess the height, area, and density of tear meniscus throughout 10 min after instillation of sodium hyaluronate (SH) of equal molecular weight at two different concentrations. Methods: Thirty-four eyes from 17 patients were enrolled in this longitudinal, nonrandomized, interventional and contralateral eye study. Tear meniscus height (TMH), corneal meniscus junction (CMJ), lower-lid meniscus junction (LLMJ), and tear meniscus area (TMA) images were obtained with the anterior segment module of the deep range imaging ocular coherence tomography ([DRI-OCT] Triton Swept-Source). Tear meniscus density (TMD) was calculated using the image processing and analysis software by Java (ImageJ program). Sodium hyaluronate artificial tears at 0.1% and 0.2% concentrations were instilled into all right and left eyes, respectively. Results: Patients' mean age was 61.05±11.43 years. Tear meniscus height, CMJ, LLMJ, and TMA measured at 1-, 5-, 7- and 10-min postinstillation of 0.1% SH proved significant differences among them (P<0.05). Sodium hyaluronate 0.2% instillation obtained similar findings, although no significant differences were found between 1- and 3-min postinstillation measurements (P>0.05). Fewer differences were found in TMD 0.2% SH group due to a lower baseline densitometry compared to the 0.1% group. Conclusion: 0.2% sodium hyaluronate achieved better TMH and TMA in 1 and 3 min after instillation than 0.1% concentration. However, there were no statistically significant differences between 0.1% and 0.2% sodium hyaluronate throughout a ten-minute longitudinal profile measurement using DRI-OCT.","PeriodicalId":502139,"journal":{"name":"Eye & Contact Lens","volume":" ","pages":"330-334"},"PeriodicalIF":2.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38745274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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