Ali Lari, Mohammed Lari, Abdulaziz Alkhandari, Ahmad Alibrahim, Ahmed Elaraby, Naser AlEnezi, Hossam Almaz, Mohammed Ibrahim
{"title":"Wide-awake local anesthesia no tourniquet (WALANT) technique versus general anesthesia for the removal of implants after ankle fracture union - A randomized controlled trial.","authors":"Ali Lari, Mohammed Lari, Abdulaziz Alkhandari, Ahmad Alibrahim, Ahmed Elaraby, Naser AlEnezi, Hossam Almaz, Mohammed Ibrahim","doi":"10.1053/j.jfas.2025.02.007","DOIUrl":"10.1053/j.jfas.2025.02.007","url":null,"abstract":"<p><p>Ankle fractures which commonly require surgical intervention, often lead to subsequent implant removal, which traditionally involves general or regional anesthesia. This study evaluates the efficacy and safety of the Wide-Awake Local Anesthesia No Tourniquet (WALANT) technique as an alternative to general anesthesia (GA) for ankle implant removal. This single-center, prospective randomized controlled trial at a tertiary orthopedic center was conducted from June 2022 to August 2024. The study included adults over 18 years who required implant removal after a united ankle fracture. Participants were randomly assigned to either the WALANT or the GA group. Out of 78 screened participants, 56 were included in the final analysis. The WALANT group showed significantly lower pain scores at 2 and 6 hours postoperatively and reduced postoperative anxiety levels compared to the GA group. Operating room times were comparable between the groups. The WALANT technique was well-tolerated, with minimal adverse effects, and was particularly effective in reducing postoperative nausea and recovery room time compared to general anesthesia. The WALANT technique for ankle implant removal is a safe and effective alternative to general anesthesia, offering benefits such as less postoperative pain, anxiety, and nausea, along with shorter recovery times. However, its success depends on careful patient selection and the surgeon's experience with the technique. This study demonstrates WALANT's potential for broader application in lower extremity surgeries, suggesting a viable option for enhancing patient outcomes and operational efficiency in orthopedic practice.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren M Christie, Steven R Cooperman, Chad A Smith, Christopher F Hyer
{"title":"Radiographic analysis of hallux valgus and first tarsometatarsal joint correction after isolated first metatarsophalangeal joint arthrodesis.","authors":"Lauren M Christie, Steven R Cooperman, Chad A Smith, Christopher F Hyer","doi":"10.1053/j.jfas.2025.02.001","DOIUrl":"10.1053/j.jfas.2025.02.001","url":null,"abstract":"<p><p>Arthrodesis of the first metatarsophalangeal joint is a common surgical procedure used to treat a variety of forefoot pathologies. The purpose of this study was to evaluate radiographic outcomes for hallux valgus and first tarsometatarsal joint alignment after first metatarsophalangeal joint arthrodesis. A retrospective radiographic analysis of the first intermetatarsal angle, hallux valgus angle, first metatarsal-cuneiform angle, and medial cuneiform-first metatarsal angle was performed preoperatively and postoperatively. One hundred eighty-eight procedures met inclusion criteria. Significant radiographic improvements were noted in first intermetatarsal angle (4.38°, P < 0.0001), hallux valgus angle (16.01°, P < 0.0001), first metatarsal-cuneiform angle (5.96°, P < 0.0001), and medial cuneiform-first metatarsal angle (5.68°, P < 0.0001). Significant radiographic improvements (P < 0.0001) were also noted when subjects were subdivided into first intermetatarsal angle ≤ 15° and > 15° for all measured angles. An isolated first metatarsophalangeal joint arthrodesis corrects both hallux valgus deformity and first tarsometatarsal alignment. These findings support that additional first ray procedures may not be required when performing a first metatarsophalangeal joint arthrodesis for hallux valgus.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Itay Ron, Shay Zvi Cherevatsky, Amir Abu Elhija, Bezalel Peskin, Nabil Ghrayeb, Doron Norman, Jacob Shapira
{"title":"Risk factors for failed below knee amputation in patients with diabetes.","authors":"Itay Ron, Shay Zvi Cherevatsky, Amir Abu Elhija, Bezalel Peskin, Nabil Ghrayeb, Doron Norman, Jacob Shapira","doi":"10.1053/j.jfas.2025.02.002","DOIUrl":"10.1053/j.jfas.2025.02.002","url":null,"abstract":"<p><p>Complications from below knee amputations (BKA), such as wound dehiscence and infections, incur high healthcare costs due to multiple and extended hospitalizations. Due to the significant morbidity still associated with proximal amputations, a careful patient selection process should be considered. This retrospective cohort study aimed to identify risk factors associated with failure of below-knee amputation (BKA), defined as progression to above-knee amputation (AKA), in patients with diabetes. Eligible patients were those who underwent primary BKA due to diabetic complications. Patients were divided into two groups: BKA and failed BKA group. Demographic variables were age, gender, BMI, smoking status, presence of vascular disease, dialysis status, nutritional status, pre-surgery hemoglobin, hemoglobin A1c, culture biopsies and use of antibiotics. Outcome variables included failure (i.e., above-knee amputation) and time to failure. Variables associated with failure of BKA included higher hemoglobin levels, prior vascular procedures, smoking, and perioperative use of oral antibiotics. Notably, oral antibiotics were linked to a higher risk of BKA failure, with patients on oral antibiotics experiencing failure more quickly than those treated with intravenous antibiotics. In addition, in the BKA group, there was a lower percentage of patients treated with PO antibiotics compared to the failed BKA group, 12 % and 19 %, respectively (P = 0.0037). This study highlights that prior vascular procedures and smoking also elevate the risk of BKA failure.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maryam Hashmi, Naila Shiraliyeva, Azucena Herrera, Humera Tabassum, Clyde Schechter, Johanna P Daily, Alyson Myers
{"title":"Who's really footing the bill? Sex and ethnicity disparities in the cost of diabetic foot ulcer-related amputations in a major healthcare system.","authors":"Maryam Hashmi, Naila Shiraliyeva, Azucena Herrera, Humera Tabassum, Clyde Schechter, Johanna P Daily, Alyson Myers","doi":"10.1053/j.jfas.2025.01.017","DOIUrl":"10.1053/j.jfas.2025.01.017","url":null,"abstract":"<p><p>Diabetic foot ulcers (DFU)-related amputations are associated with enormous expenditures. Understanding why amputation services are more expensive for certain patients is crucial for reforming healthcare expenditure and insurance practices. This analysis examined differences in cost of DFU-related amputations services in patients insured by HealthFirst, a Medicaid-managed insurance company. Data from HealthFirst were collected for patients admitted for DFU-related amputation between 2021 and 2023. Demographics and laboratory values were extracted from the electronic health record. Demographics, laboratory values, total costs, and paid amounts were analyzed. Clinical variables were tested as predictors of expenditure levels through bivariate analysis. In our cohort of 140 patients, 65.3 % of patients were male, with a mean age of 60.6 (S.D. 12) years, diagnosis of type 2 diabetes (96.3 %) and ethnically Hispanic-Latino (56.1 %). Common comorbidities were chronic kidney disease (57.9 %) and hypertension (86.2 %). DFU- related amputation charges were higher for Hispanic-Latino individuals, RR 1.97 (CI 1.04, 3.71), and those with chronic kidney disease, RR 1.36 (CI 1.0, 1.86) and moderately associated with female sex. Serum glucose, RR 1 (1.0 -1.0), body mass index, RR 0.98 (0.96-1.0), and Hemoglobin A1c, RR 1.01 (CI 0.93-1.09) were not found to be associated with higher cost. Overall, Hispanic-Latino individuals, persons with chronic kidney disease, and women incurred higher DFU related charges, highlighting the need for heightened DFU prevention in these populations.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harjot Uppal, Daniel Garcia, Isaac Soliman, Dylan Dupont, Nikhil Sahai, Andrew McGinniss, Arash Emami
{"title":"Readability of foot and ankle patient-reported outcomes: Alignment with National institutes of health and american medical association standards.","authors":"Harjot Uppal, Daniel Garcia, Isaac Soliman, Dylan Dupont, Nikhil Sahai, Andrew McGinniss, Arash Emami","doi":"10.1053/j.jfas.2025.01.016","DOIUrl":"10.1053/j.jfas.2025.01.016","url":null,"abstract":"<p><p>Patient-reported outcome measures are essential tools for assessing surgical interventions, capturing patient perspectives on functionality, symptoms, and quality of life. However, ensuring that these measures are easily understandable is crucial for accurate patient responses. The National Institutes of Health and American Medical Association recommend that patient materials be written at or below a sixth-grade reading level. This study evaluated the readability of 45 commonly used patient-reported outcome measures in foot and ankle surgery to determine alignment with these guidelines. A readability analysis was conducted using the Flesch Reading Ease Score and the Simple Measure of Gobbledygook Index, with a threshold of a Flesch Reading Ease Score of at least 80 or a Simple Measure of Gobbledygook Index below 7 indicating a sixth-grade or lower reading level. The average readability scores indicated an eighth to ninth-grade reading level, with only 31% of patient-reported outcome measures meeting the readability threshold. Among the least readable measures were the American Orthopaedic Foot and Ankle Society Clinical Rating Scales for various foot and ankle regions and the Ankle Osteoarthritis Scale. These findings suggest that most foot and ankle surgery patient-reported outcome measures are above the recommended readability level, potentially hindering patient comprehension and response accuracy. Improving the readability of patient-reported outcome measures, either by developing new tools or modifying existing ones, may enhance the accessibility and reliability of patient-reported data.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lateral Wall Displacement of Calcaneal Fracture Leading to Peroneal Tendon Dislocation: Effect of the Distance of Lateral Wall Displacement on the incidence of Peroneal Tendon Dislocation.","authors":"Toshiyuki Shimizu, Tetsuro Kokubo, Yoshihisa Suzuki","doi":"10.1053/j.jfas.2025.01.011","DOIUrl":"10.1053/j.jfas.2025.01.011","url":null,"abstract":"<p><p>Peroneal tendon dislocation accompanying an intra-articular calcaneal fracture is uncommon; however, such dislocations are often missed in the acute phase. Although risk factors have been reported, the correlation between the degree of lateral wall displacement of the fractured calcaneus and the incidence of peroneal tendon dislocation remains unclear. We retrospectively analyzed computed tomography scans of 61 patients who had calcaneal fractures to examine peroneal tendon dislocation and the association with degree of lateral wall displacement and presence of fleck signs, between peroneal tendon dislocation and non-dislocation cases. Peroneal tendon dislocation was observed in 11.5 % (7/61) of the scan of patients with acute calcaneal fractures. The mean measurement of lateral wall displacement of the calcaneus was -3.3 (-11.1 to 8.9) mm. The fleck sign on radiographic images was evident in two cases (3.3 %), whereas the fleck sign on scans was evident in three cases (4.9 %). The mean measurement was significantly greater in cases with peroneal tendon dislocation than in those without dislocation (3.0 vs -4.1 mm, P<.05). The incidence of peroneal tendon dislocation and the lateral wall distance were significantly associated with the severity of calcaneal fractures, according to the Sanders classification system. The area under the curve generated for the medial deviation of the receiver operating characteristic curve was 0.976 and the cut-off value was 0.9. This study showed that lateral wall displacement is related to peroneal tendon dislocation and that the measurement of displacement using computed tomography scans can be a useful indicator of peroneal tendon dislocation.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simultaneous bilateral surgery for accessory naviculars does not have a negative effect on postoperative outcome.","authors":"Miyu Inagawa, Yasuyuki Jujo, Yoshiharu Shimozono, Kosui Iwashita, Erika Nicole L Chua, Keong Joo Lee, Takashi Watanabe, Masato Takao","doi":"10.1053/j.jfas.2025.01.014","DOIUrl":"10.1053/j.jfas.2025.01.014","url":null,"abstract":"<p><p>Accessory navicular tends to occur bilaterally; however, unilateral surgery is performed more often than simultaneous bilateral surgery. The purpose of this study was to compare the clinical outcomes of unilateral and simultaneous bilateral surgeries. Between 2018 and 2022, 42 feet in 26 patients underwent resection for a type-II symptomatic accessory navicular. Patients were classified into 2 groups according to unilateral (group Uni) or bilateral (group Bi) surgery. Clinical outcomes and time to postoperative walking, jogging, and return to full athletic activities were compared between the groups. There were 10 and 16 patients in group Uni and group Bi, respectively. A comparison between group Uni and group Bi revealed no significant differences in the number of days until walking, jogging, or full athletic activity. There were no statistically significant differences between groups in terms of mean postoperative SAFE-Q scores for any of the subscales. To avoid the influence of age, stratified analysis was conducted by dividing the participants into those aged ≤ 16 years and those aged > 16 years. No statistically significant differences were observed between the group Uni and group Bi. Similar results were also observed in the t-test. In addition, we conducted a similar analysis by changing the age cutoff to 15 or 19 years, but no qualitative changes were observed in the results. There is no clear evidence that bilateral surgery for type-II symptomatic bilateral accessory navicular delays recovery, and there might be no need to avoid bilateral simultaneous surgery, regardless of age.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Taday, E Schiffner, S V Gehrmann, M Prost, J Windolf, D Latz
{"title":"Volumetric assessment of the soft tissue envelope in unilateral closed ankle fractures using a portable 3D scanner.","authors":"R Taday, E Schiffner, S V Gehrmann, M Prost, J Windolf, D Latz","doi":"10.1053/j.jfas.2025.01.015","DOIUrl":"10.1053/j.jfas.2025.01.015","url":null,"abstract":"<p><p>Management of ankle fractures necessitating surgery is impacted by soft tissue swelling, often delaying open reduction and internal fixation (ORIF). Subjective evaluations are inconsistent, and traditional measurement methods are often inaccurate or impractical. This prospective observational study included 17 adults with unilateral closed ankle fractures requiring surgical fixation. A measurement protocol on regions of interest (ROI) was utilized, employing a handheld 3D scanner for daily volume scans of the fractured ankle, comparing these measurements with subjective assessments of swelling using a numerical scale. The 3D scanner detected significant soft tissue volume reductions of the ROI over 14 days, with reductions of 25 ± 25 % in the lower limb and 16 ± 9 % in the ankle. Significant swelling reduction was noted from day 8, preceding surgeons' assessments (days 11-14). The scanner exhibited high reproducibility, providing an objective tool for comparative studies on decongestive measures in perioperative soft tissue management.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lolita Micicoi, Barbara Piclet-Legré, Tristan Fauchille, Alexandre Rudel, Nicolas Bronsard, Jean-François Gonzalez, Matthieu Ollivier
{"title":"Morphological analysis of the retrotalar pulley and its role in flexor hallucis longus impingement: Insights from a CT-based study.","authors":"Lolita Micicoi, Barbara Piclet-Legré, Tristan Fauchille, Alexandre Rudel, Nicolas Bronsard, Jean-François Gonzalez, Matthieu Ollivier","doi":"10.1053/j.jfas.2025.01.002","DOIUrl":"10.1053/j.jfas.2025.01.002","url":null,"abstract":"<p><p>The Flexor Hallucis Longus (FHL) is a muscle that can be subject to multiple conflicts. The most common conflict is due to inflammation of the tendon at the retrotalar pulley. The constraints exerted on the FHL are responsible for a pathology called functional Hallux Limitus. The purpose of this anatomical study is to describe morphologic finding about retrotalar pulley, which may account the impingement between FHL and the hindfoot. Using a retrospective approach at a single center, a detailed analysis was conducted on a cohort of 350 patients. Precise measurements were taken to document the angles, areas, and distances that define the relationship between the Flexor Hallucis Longus (FHL) tendon and its surrounding anatomical structures. The angle between the retrotalar pulley and the sustentaculum tali exhibited a range of 124 to 170 degrees in profile and 113.3 to 178 degrees in frontal view. The dimensions of the retrotalar pulley varied from 1.1 to 54 mm², while the posterolateral and posteromedial tubercles displayed dimensions ranging from 3.4 to 77.9 mm² and 2.6 to 35.2 mm², respectively. Distances between posterior tubercles further underscored the anatomical diversity, ranging from 4.3 to 17 cm proximally and 10.5 to 18.4 cm distally. In unraveling the morphological complexities surrounding FHL impingement, this study provides valuable insights into the biomechanical intricacies of the foot. These findings not only deepen our understanding of musculoskeletal anatomy but also pave the way for future investigations into the dynamic interplay between structure and function in the lower extremities.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of sciatic nerve block on sciatic nerve depth and pain level in patients with ankle fracture based on different approaches under ultrasound guidance.","authors":"Haiyun Dong, Penglei Ma, Jingyu Li, Yulin Wu, Wei Wang, Caixia Wang","doi":"10.1053/j.jfas.2025.01.013","DOIUrl":"10.1053/j.jfas.2025.01.013","url":null,"abstract":"<p><p>To investigate the clinical efficacy of using different approach sciatic nerve blocks on the sciatic nerve depth and pain degree in patients with ankle fracture. A retrospective analysis was conducted on 151 patients with ankle fractures who were admitted to the hospital from May 2020 to May 2023. The patients were divided into a control group (n=76) using the greater trochanteric plane approach (GTA) and an observation group (n=75) using the suprapopliteal approach (PA). Perioperative related indexes, pain levels, muscle strength, hemodynamic indexes, and adverse reactions were compared between the two groups. There was no significant difference in operation time between the two groups. The nerve block operation time and onset time were lower in the observation group, while the maintenance time of nerve block was higher in the observation group(P<0.05). The visual analogue scale (VAS) scores at 2h, 12h, and 24h postoperatively were lower in the observation group. Muscle strength of the posterior femoral muscle group was significantly better in the observation group at 8h after surgery. Hemodynamic indexes were lower in the observation group at 15minutes and 30minutes after anesthesia. The total incidence of adverse reactions was lower in the observation group compared to the control group. Ultrasound-guided sciatic nerve block using the suprapopliteal approach in patients with ankle fractures can help stabilize muscle strength and hemodynamics, alleviate pain symptoms, and avoid motor block and adverse reactions. This approach is recommended for adoption.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}