{"title":"A comparative study of postoperative clinical outcomes of lateral ankle ligament repair for early-stage ankle osteoarthritis in middle-aged and elderly patients.","authors":"Yasuyuki Jujo, Jun Horng Tan, Kazuaki Okugura, Yukinori Mori, Kenta Komesu, Masato Takao, Taihei Miura","doi":"10.1053/j.jfas.2025.05.003","DOIUrl":"https://doi.org/10.1053/j.jfas.2025.05.003","url":null,"abstract":"<p><p>Although lateral ankle ligament repair has demonstrated favorable postoperative outcomes, few studies have focused on elderly patients. The aim of this study was to compare the postoperative clinical outcomes of lateral ankle ligament repair in middle-aged and elderly patients with early-stage ankle osteoarthritis (OA). This study was a retrospective analysis of 99 patients aged 40 years or older with chronic lateral ankle instability (LAI) associated with ankle OA who were followed up for at least 12 months after surgery. The patients were divided into two groups: 60 patients in the middle-aged group (40-64 years) and 39 patients in the elderly group (≥65 years), all of whom underwent lateral ankle ligament repair. The recovery time to preoperative walking levels and the Self-Administered Foot Evaluation Questionnaire (SAFE-Q) scores preoperatively and postoperatively were investigated and compared between the two groups. Compared with the preoperative scores, SAFE-Q scores improved significantly across all items in both groups at 12 months post-surgery. There was no difference in pain or pain-related scores between the two groups up to 12 months post-surgery. Furthermore, all patients recovered to their preoperative walking levels or above. However, the elderly group took significantly longer to recover after surgery than the middle-aged group did. Lateral ankle ligament repair yields favorable clinical outcomes even in elderly patients. However, elderly patients took significantly longer to recover walking levels after surgery than middle-aged patients. Therefore, preoperative patient education and postoperative rehabilitation protocols may need to be adjusted accordingly.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhruv Nandakumar, Benjamin M Conover, Matthew J Johnson, Katherine M Raspovic, Dane K Wukich
{"title":"Outcomes of open or closed treatment of foot fractures: A database study comparing patients with and without diabetes.","authors":"Dhruv Nandakumar, Benjamin M Conover, Matthew J Johnson, Katherine M Raspovic, Dane K Wukich","doi":"10.1053/j.jfas.2025.05.004","DOIUrl":"10.1053/j.jfas.2025.05.004","url":null,"abstract":"<p><p>Treatment of ankle and foot fractures in patients with diabetes mellitus (DM) is challenging, and complications may arise. Although much data exists on complication rates in tibial, fibular, and malleolar fractures, there exists a comparable lack of data on complication rates in fractures of the tarsal, metatarsal, and phalanx bones of the foot. Therefore, we aimed to compare post-procedural outcomes after such fractures in diabetic vs non-diabetic patients. A commercially available de-identified database was searched using ICD-10 codes for the open or closed surgical treatment in patients with fractures of the calcaneus, cuboid, navicular, talus, cuneiforms, metatarsals, and phalanges from 2010 to 2023. Patients with at least 1 year of post-procedural follow-up were included. We then separated patients into two groups: those with diabetes (108,603, 26.4 %) and those without diabetes (302,464, 73.6 %). Post-procedural complications assessed including those related to hardware when surgical treatment was pursued (reoperation, non-union, malunion, delayed union, wound disruption, surgical site infection) and health complications after fracture treatment (AKI, DVT, MI, pneumonia, sepsis) were assessed at 1 year and odds ratios were used to compare rates of these complications in diabetics vs non-diabetics for each bone. Rates of complications after fracture treatment were found to be significantly higher in all bones for diabetic patients compared to non-diabetic patients.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nolan M Reinhart, Jackson P Tate, Chauncey A Bridges, James Clemmons, Murphy P Martin, Olivia C Lee, William F Sherman
{"title":"Are we putting our best foot forward? The effect of insurance type on ankle fracture complications and delays in care: a retrospective two-year analysis.","authors":"Nolan M Reinhart, Jackson P Tate, Chauncey A Bridges, James Clemmons, Murphy P Martin, Olivia C Lee, William F Sherman","doi":"10.1053/j.jfas.2025.04.009","DOIUrl":"10.1053/j.jfas.2025.04.009","url":null,"abstract":"<p><p>This study investigates the influence of insurance type on delays in surgical management and postoperative complications in patients with closed operative ankle fractures. A retrospective cohort study was conducted using the PearlDiver Mariner database, analyzing 37,706 ankle fracture patients who underwent open reduction internal fixation (ORIF). Patients were grouped by insurance type (Medicaid vs private insurance), and the time from fracture diagnosis to surgery was compared. Complications including hardware infection, revision surgery, mechanical failure, nonunion, malunion, and postoperative wound issues were analyzed within two years post-surgery. A higher proportion of Medicaid patients had surgical delays beyond 10 days from initial presentation compared to privately insured patients (28.6 vs 22.2 %, p < 0.001). Medicaid patients had higher rates of any orthopedic complications (odds ratio (OR): 1.27, 95 % confidence interval (CI): 1.19 - 1.37), including revision ORIF (OR: 1.33, CI: 1.16 - 1.54), mechanical failure (OR:1.24, CI: 1.03 - 1.49), nonunion or malunion (OR: 1.35, 1.17 - 1.55), and posttraumatic arthritis (OR: 1.26, 1.08 - 1.48). Although complications like wound infection and amputation were more frequent among Medicaid patients, these differences were not statistically significant. Medicaid patients experience longer delays in surgical management and higher rates of complications after ankle fractures compared to privately insured patients.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of surgery for ankle osteoarthritis on locomotive syndrome.","authors":"Kanu Shimokawa, Hidenori Matsubara, Satoshi Kato, Toshifumi Hikichi, Yuki Fushitani, Yusuke Nakazawa, Satoru Demura","doi":"10.1053/j.jfas.2025.05.001","DOIUrl":"10.1053/j.jfas.2025.05.001","url":null,"abstract":"<p><p>Locomotive syndrome (LS) is characterized by a decline in locomotor function due to musculoskeletal disorders. However, few studies have explored its association with ankle osteoarthritis (AOA) or surgical impact. This study evaluated LS and its improvement following corrective osteotomy (CO) or arthrodesis for AOA and compared outcomes between procedures. LS stages, ranging from 0 (healthy) to 3 (most declined), were assessed preoperatively and at 12 months postoperatively using the stand-up test (ability to rise from different heights), two-step test (maximum stride length over two strides), and GLFS-25 (self-reported locomotor function). Pre- and postoperative comparisons and group differences were analyzed, with p < 0.05 considered significant. Forty patients were included. All patients had a preoperative LS stage 1 to 3, with a prevalence of LS stage 3 of 57.5 %. At 12 months after surgery, the prevalence of LS stage 1 to 3 was 95.0 %, but the prevalence of LS stage 3 decreased to 30.0 %. At least one LS stage improved postoperatively in 19 patients (47.5 %). There was no significant difference between pre- and post-operative stand-up test results (p = 0.74), but the two-step test and GLFS-25 improved significantly postoperatively (two step: p = 0.01, GLFS-25: p < 0.001). The GLFS-25 improved significantly postoperatively in both groups (corrective osteotomy: p = 0.001, Arthrodesis: p = 0.01); however, the two-step test improved significantly postoperatively only in the corrective osteotomy group (corrective osteotomy: p = 0.02, Arthrodesis: p = 0.44). In conclusion, ankle osteoarthritis may be a factor affecting LS, and corrective osteotomy tended to be more effective in improving the two-step test.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua Morningstar, Bradley J Lauck, Nicholas Bank, Trapper Lalli
{"title":"Impact of glucagon-like peptide-1 receptor agonists on postoperative outcomes following ankle fracture open reduction and internal fixation.","authors":"Joshua Morningstar, Bradley J Lauck, Nicholas Bank, Trapper Lalli","doi":"10.1053/j.jfas.2025.05.002","DOIUrl":"10.1053/j.jfas.2025.05.002","url":null,"abstract":"<p><p>Glucagon-like peptide-1 receptor agonists (GLP-1RA) are quickly growing in popularity as effective tools in the management of diabetes and weight loss. Despite this increased usage, there is a paucity of literature investigating the use of GLP-1RA in patients with ankle fractures. This study aims to compare the outcomes of patients undergoing ankle fracture open reduction and internal fixation (ORIF) receiving therapy with GLP-1RA to those not receiving treatment. A retrospective analysis was performed utilizing the TriNetX research network to query patients who underwent ankle fracture ORIF between 2000-2024. Two cohorts were established according to preoperative GLP-1RA usage with 1:1 matching by propensity scores for demographics and comorbidities. Primary outcomes included the risk of postoperative complications (i.e. infection, sepsis, wound dehiscence, cellulitis, thrombosis, nonunion, reoperation, revision, etc.) at 30-days, 90-days, 1-year, and 5-years. There were 123,546 patients not taking GLP-1RA and 1,173 patients taking GLP-1RA who underwent ORIF for an ankle fracture, with propensity score matching resulting in two cohorts of 1,173 patients each. After matching, there were no significant differences in demographics or comorbidities, including a 75.6 % prevalence of diabetes mellitus and 68.7 % prevalence of overweight or obesity in both cohorts. At 30-days postoperatively, the no GLP-1RA cohort had a significantly higher rate of removal of hardware (Odds Ratio [OR] 1.953, 95 % Confidence Interval (CI) 1.062-3.591); no other complications demonstrated significant differences at 30-days, 90-days, 1-year, or 5-years postoperatively. These findings further underscore the low risk of preoperative GLP-1RA usage noted in other orthopaedic procedures.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shyam S Ramachandran, Seth Reine, Holden Archer, Jennifer Koay, Dane K Wukich, Avneesh Chhabra
{"title":"Inter-reader reliability in multi-plane and multi-time point Hallux valgus correction evaluation on post-operative weight-bearing radiographs from a prospective multi-center trial and correlation with patient reported outcome measures.","authors":"Shyam S Ramachandran, Seth Reine, Holden Archer, Jennifer Koay, Dane K Wukich, Avneesh Chhabra","doi":"10.1053/j.jfas.2025.04.011","DOIUrl":"10.1053/j.jfas.2025.04.011","url":null,"abstract":"<p><p>The primary purpose of this study was to determine interreader reliability (IRR) of hallux valgus (HV) related parameters on different time-points in dorsoplanar and coronal planes, i.e. hallux valgus angle (HVA), metatarsal rotation, sesamoid subluxation, metatarsal sesamoid osteoarthritis, tibial sesamoid point, and lateral round sign. The secondary purpose was to correlate these measurements with patient-reported outcome measures (PROMs) at the initial presentation for HV surgery and at 6 weeks, 4 months, 6 months, 12 months, and 24 months. Radiographic imaging and PROMs were collected at 5 different postoperative time points. Two musculoskeletal radiologists independently performed all readings and foot measurements blinded to each other's reads and the clinical information. Intraclass coefficient and kappa were obtained for interreader analysis. A partial spearman rank order was used to correlate radiographic foot measurements and PROMs. Across all 5 follow-up time points (6 weeks, 4 months, 6 months, 12 months, and 24 months), we found excellent IRR for HVA and poor reliability for lateral round sign, sesamoid subluxation, and metatarsal-sesamoid OA. We found excellent IRR for TSP at all follow-up time points except for at 6 weeks. There was a weak, positive correlation between sesamoid subluxation and PROMIS depression score at 24-month follow-up (R=0.21), and a negative correlation between metatarsal-sesamoid OA and PROMIS social score at 24-month follow-up (R=-0.21). We report excellent reproducibility for HVA in post-operative radiographs but variable- poor to excellent IRR for a range of HV-related parameters assessed on the axial view. There were no major trends in the correlation between the quantitative radiographic foot measurements and PROMs except for some weak correlations.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kanika Kochhar DPM , Sari Priesand DPM , Matheos Yosef , Brian M. Schmidt DPM
{"title":"Diabetic foot infection severity as a predictor of re-ulceration following partial forefoot amputation","authors":"Kanika Kochhar DPM , Sari Priesand DPM , Matheos Yosef , Brian M. Schmidt DPM","doi":"10.1053/j.jfas.2024.10.012","DOIUrl":"10.1053/j.jfas.2024.10.012","url":null,"abstract":"<div><div>Diabetic foot ulcer re-ulceration is a common complication following partial forefoot amputation. Re-ulceration refers to the occurrence of a skin break that penetrates through the epidermis and a portion of the dermis, occurring at any site on either the same or opposite foot where amputation took place. Treatment for diabetic foot ulcers often includes an extended course of local wound care and may entail surgical procedures. The aim of this study was to evaluate the incidence of re-ulceration in people who underwent a partial forefoot amputation. We hypothesized there is an association between amputation type and occurrence of re-ulceration. A retrospective chart review was performed for 253 individuals between December 2015 and September 2020. One hundred eleven people met eligibility criteria and were divided into two cohorts: those who re-ulcerated and those who did not. Univariable analysis was performed for available demographic, clinical, laboratory and outcome data. Seventy-nine of the 111 (71.2 %) subjects re-ulcerated status post partial forefoot amputation. Based on the Infectious Disease Society of America (IDSA) classification for assessment of infection, the average severity for the re-ulceration group was 2.62, while for the no re-ulceration group was 2.22 (<em>p <</em> 0.001). The median time to re-ulceration was 186 days. No association was demonstrated between amputation location and incidence of re-ulceration. Patients with higher diabetic foot infection severity based on IDSA classification are at greater risk for developing re-ulceration following a partial forefoot amputation.</div></div>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":"64 3","pages":"Pages 238-242"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian X. Lava MS , Karen R. Li BBA , Elonay Yehualashet BS , Rachel N. Rohrich BS , Tiffanie Liu DPM, AACFAS , Richard C. Youn MD , Karen K. Evans MD , Christopher E. Attinger MD
{"title":"Fillet of toe flap coverage for non-traumatic foot amputations: A retrospective review of 70 patients","authors":"Christian X. Lava MS , Karen R. Li BBA , Elonay Yehualashet BS , Rachel N. Rohrich BS , Tiffanie Liu DPM, AACFAS , Richard C. Youn MD , Karen K. Evans MD , Christopher E. Attinger MD","doi":"10.1053/j.jfas.2024.10.010","DOIUrl":"10.1053/j.jfas.2024.10.010","url":null,"abstract":"<div><div>Fillet of toe flap (FTF) leverages the “spare parts” algorithm in reconstructive surgery–utilizing tissue from amputated or otherwise non-salvageable body parts, thus avoiding donor-site morbidity. This study assesses the efficacy of FTF coverage in non-traumatic foot amputations. A retrospective review of patients undergoing foot amputation with FTF coverage between January 2013 to August 2023 was conducted. Patient characteristics, operative details, and outcomes were collected. Primary outcome was FTF survival (no necrosis ≤7 days postoperatively). Secondary outcome was acute complications (≤42 days postoperatively). A total of 70 patients were included. Mean age was 65.0±13.7 years. Median Charlson Comorbidity Index was 6.0 (interquartile range [IQR]: 4.0-7.0). The most common wound location was the hallux (n=34). In 45 (64.2 %) patients with preoperative angiography, the patency rates were: first dorsal metatarsal artery (n=10, 22.2 %), lateral plantar artery (n=7, 15.6 %), medial plantar artery (n=6, 13.3 %), and dorsalis pedis artery (n=4, 8.9 %). Mean follow-up duration was 9.0 (IQR: 32) months. Fifteen (21.4 %) patients experienced at least one acute complication: deep surgical site infection (SSI; i.e., abscess, gangrenous necrosis; n=13, 18.6 %) and cellulitis (n=7, 10.0 %). Eleven (15.7 %) patients required reoperation for debridement (n=4, 5.7 %), wound closure (n=4, 5.7 %), flap necrosis (n=3, 4.3 %), incision and drainage (n=1, 1.4 %), split-thickness skin grafting (n=1, 1.4 %), and foreign body exploration (n=1, 1.4 %). FTF survival was 94.2 % (n=66). FTF facilitates reconstruction in complex cases and should be integrated into each chronic LE wound algorithm to avoid additional donor-site morbidity, and to facilitate stump-length preservation or limb salvage.</div></div>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":"64 3","pages":"Pages 228-232"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kunpeng Leng MD, Yang Liu MD, Yutong Meng MD, Junlin Zhou MD
{"title":"The comparative study of clinical outcomes among early functional treatment, immobilization treatment and ulnar plate fixation for displaced or comminution fifth metatarsal base fractures","authors":"Kunpeng Leng MD, Yang Liu MD, Yutong Meng MD, Junlin Zhou MD","doi":"10.1053/j.jfas.2024.11.004","DOIUrl":"10.1053/j.jfas.2024.11.004","url":null,"abstract":"<div><div>The optimal treatment for displaced or comminution fifth metatarsal base fractures remain debated. Ninety displaced or comminution fifth metatarsal base fractures patients were randomly selected into three groups: the ulnar hook plate fixation group (n=30), the immobilization treatment group (n=18), and the early functional group (n=30). The assessed factors included the duration until union, time to resume daily activities, American Orthopaedic Foot and Ankle Society (AOFAS) scores, Foot and Ankle Disability Index (FADI) scores, visual analog scale (VAS) ratings and occurrence of complications. The VAS scores showed no significant differences observed among the three treatments. The mean AOFAS score and mean FADI after treatment in the plate group and exhibited significant better than that of the immobilization group and the early functional group at 1 moth, 3 months and 6 months (P˂0.05). After a duration of 12 months, all three treatments exhibited comparable outcomes and facilitated restoration of daily activities. In the plate group, one patient developed a wound infection, one patient experienced sural nerve injury or irritation, and three patients exhibited implant prominence. One patient encountered nonunion in the immobilization group.The union time and the time of return to daily activities and the early functional group exhibited significant shorter durations than that of the immobilization group and the plate group(P˂0.05). Overall, the early functional treatment is recommended for managing displaced or comminution fifth metatarsal base fractures.</div></div>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":"64 3","pages":"Pages 256-261"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanwen Zhang (Master of Medicine) , Wei Deng (Master of Medicine) , Qingsong Zhou (Master of Medicine), Yong Yin (Master of Medicine)
{"title":"Wide-margin excision of diffuse ankle's tendon sheath giant cell tumor in 24 patients: A mid-term study","authors":"Hanwen Zhang (Master of Medicine) , Wei Deng (Master of Medicine) , Qingsong Zhou (Master of Medicine), Yong Yin (Master of Medicine)","doi":"10.1053/j.jfas.2024.11.007","DOIUrl":"10.1053/j.jfas.2024.11.007","url":null,"abstract":"<div><div>Giant cell tumour of tendon sheath (TSGCT) is an uncommon soft tissue tumor, especially in its diffuse subtype (D-TSGCT), which is rare and associated with a high recurrence rate after treatment. This condition significantly affects joint function and quality of life. This retrospective study evaluated the clinical characteristics, surgical outcomes, and long-term follow-up of 24 patients who underwent wide-margin resection for ankle D-TSGCT from 2011 to 2018. The average patient age was 36.5 years, with common symptoms including palpable masses and ankle swelling. All patients received wide-margin resection, with a mean follow-up period of 75.7 months. Tumor recurrence occurred in five patients (21 %), with complications included postoperative infections, surgical site pain, ankle instability, and stiffness. There was a significant improvement in the Musculoskeletal Tumor Society (MSTS) scores post-surgery. Additionally, the Foot and Ankle Ability Measure (FAAM) showed improvements in daily living and physical activities, though Ankle Joint Functional Assessment Tool (AJFAT) scores did not demonstrate significant change. These findings indicate that wide-margin resection is an effective treatment for D-TSGCT, preserving ankle function and demonstrating a low recurrence rate, although it may lead to ankle instability requiring careful postoperative monitoring and rehabilitation.</div></div>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":"64 3","pages":"Pages 272-278"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}