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The Journal of Trauma and Acute Care Surgery最新文献

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Tranexamic acid is not associated with a higher rate of thrombotic-related reintervention after major vascular injury repair. 氨甲环酸与大血管损伤修复后血栓相关的再介入率升高无关。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004227
Sina Asaadi, Kaushik Mukherjee, Ahmed M Abou-Zamzam, Liang Ji, Xian Luo-Owen, Maryam B Tabrizi, Richard D Catalano, Joseph J Dubose, Martin G Rosenthal
{"title":"Tranexamic acid is not associated with a higher rate of thrombotic-related reintervention after major vascular injury repair.","authors":"Sina Asaadi, Kaushik Mukherjee, Ahmed M Abou-Zamzam, Liang Ji, Xian Luo-Owen, Maryam B Tabrizi, Richard D Catalano, Joseph J Dubose, Martin G Rosenthal","doi":"10.1097/ta.0000000000004227","DOIUrl":"https://doi.org/10.1097/ta.0000000000004227","url":null,"abstract":"Tranexamic acid (TXA) is associated with lower mortality and transfusion requirements in trauma patients, but its role in thrombotic complications associated with vascular repairs remains unclear. We investigated whether TXA increases the risk of thrombosis-related technical failure (TRTF) in major vascular injuries (MVI).","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of lipid metabolites derived from gut microbiota in ischemia-reperfusion model. 分析缺血再灌注模型中来自肠道微生物群的脂质代谢物。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004230
Keita Nakatsutsumi, Koji Morishita, Todd W Costantini, Tomohiro Adachi, Akira Suekane, Keisuke Suzuki, Mitsuaki Kojima, Makoto Arita, Yasuhiro Otomo
{"title":"Analysis of lipid metabolites derived from gut microbiota in ischemia-reperfusion model.","authors":"Keita Nakatsutsumi, Koji Morishita, Todd W Costantini, Tomohiro Adachi, Akira Suekane, Keisuke Suzuki, Mitsuaki Kojima, Makoto Arita, Yasuhiro Otomo","doi":"10.1097/ta.0000000000004230","DOIUrl":"https://doi.org/10.1097/ta.0000000000004230","url":null,"abstract":"Disruption of intestinal barrier caused by intestinal ischemia due to hemorrhagic shock, is associated with the pathogenesis of multiple organ dysfunction (MOD) after severe trauma. Mesenteric lymph (ML) plays an important role as a route for transporting inflammatory mediators, including lipids. Post-biotics, such as 10-hydroxy-cis-12-octadecenoic acid (HYA), have received much attention as a treatment option. However, the relationship between post-biotics and MOD has yet to be clarified. The aim of the present study is to analyze lipid metabolites derived from gut microbiota in the intestinal ischemia/reperfusion (IR) rat model.","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long wavelength light exposure reduces systemic inflammation coagulopathy, and acute organ injury following polytrauma in mice. 长波长光照射可减少小鼠全身炎症、凝血病和多发性创伤后的急性器官损伤。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004234
Mohammadreza Zarisfi, Reem Younes, Nijmeh Alsaadi, Zeyu Liu, Patricia Loughran, Kelly Williamson, Philip C Spinella, Susan Shea, Matthew R Rosengart, Elizabeth A Andraska, Matthew D Neal
{"title":"Long wavelength light exposure reduces systemic inflammation coagulopathy, and acute organ injury following polytrauma in mice.","authors":"Mohammadreza Zarisfi, Reem Younes, Nijmeh Alsaadi, Zeyu Liu, Patricia Loughran, Kelly Williamson, Philip C Spinella, Susan Shea, Matthew R Rosengart, Elizabeth A Andraska, Matthew D Neal","doi":"10.1097/ta.0000000000004234","DOIUrl":"https://doi.org/10.1097/ta.0000000000004234","url":null,"abstract":"Evidence suggests that variation in light exposure strongly influences the dynamic of inflammation, coagulation, and the immune system. Polytrauma induces systemic inflammation that can lead to end-organ injury. Here, we hypothesize that alterations in light exposure influence post-trauma inflammation, coagulopathy, and end-organ injury.","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopaedic trauma patients: a secondary analysis of the PREVENT CLOT trial. 骨科创伤患者服用阿司匹林与低分子量肝素的风险分层血栓预防效果：PREVENT CLOT 试验的二次分析。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004226
Nathan N O'Hara, Robert V O'Toole, Katherine P Frey, Renan C Castillo, Joseph Cuschieri, Elliott R Haut, Gerard P Slobogean, Reza Firoozabadi, Ashley Christmas, William T Obremskey, Anthony R Carlini, Greg Gaski, Matthew E Kutcher, Debra Marvel, Deborah M Stein
{"title":"Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopaedic trauma patients: a secondary analysis of the PREVENT CLOT trial.","authors":"Nathan N O'Hara, Robert V O'Toole, Katherine P Frey, Renan C Castillo, Joseph Cuschieri, Elliott R Haut, Gerard P Slobogean, Reza Firoozabadi, Ashley Christmas, William T Obremskey, Anthony R Carlini, Greg Gaski, Matthew E Kutcher, Debra Marvel, Deborah M Stein","doi":"10.1097/ta.0000000000004226","DOIUrl":"https://doi.org/10.1097/ta.0000000000004226","url":null,"abstract":"The PREVENT CLOT trial concluded that thromboprophylaxis with aspirin was noninferior to low-molecular-weight heparin (LMWH) in preventing death after orthopaedic trauma. However, it was unclear if these results applied to patients at highest risk of thrombosis. Therefore, we assessed if the effect of aspirin versus LMWH differed based on patients' baseline risk of venous thromboembolism (VTE).","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Older females have increased mortality after trauma as compared to younger females and males, associated with increased fibrinolysis. 与年轻女性和男性相比，老年女性在创伤后的死亡率更高，这与纤维蛋白溶解增加有关。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004235
R W G Dujardin, D J B Kleinveld, C E van den Brom, L M G Geeraedts, E Beijer, C Gaarder, K Brohi, S Stanworth, P I Johansson, J Stensballe, M Maegele, N P Juffermans
{"title":"Older females have increased mortality after trauma as compared to younger females and males, associated with increased fibrinolysis.","authors":"R W G Dujardin, D J B Kleinveld, C E van den Brom, L M G Geeraedts, E Beijer, C Gaarder, K Brohi, S Stanworth, P I Johansson, J Stensballe, M Maegele, N P Juffermans","doi":"10.1097/ta.0000000000004235","DOIUrl":"https://doi.org/10.1097/ta.0000000000004235","url":null,"abstract":"Female sex may provide a survival benefit after trauma, possibly attributable to protective effects of estrogen. This study aims to compare markers of coagulation between male and female trauma patients across different ages.","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endotheliopathy of Trauma in Children: The Association of Syndecan-1 with Injury and Poor Outcomes. 儿童创伤的内皮病变：Syndecan-1与损伤和不良后果的关系。
The Journal of Trauma and Acute Care Surgery Pub Date : 2023-12-08 DOI: 10.1097/ta.0000000000004229
Katrina M Morgan, Elissa Abou-Khalil, Barbara A Gaines, Christine M Leeper
{"title":"Endotheliopathy of Trauma in Children: The Association of Syndecan-1 with Injury and Poor Outcomes.","authors":"Katrina M Morgan, Elissa Abou-Khalil, Barbara A Gaines, Christine M Leeper","doi":"10.1097/ta.0000000000004229","DOIUrl":"https://doi.org/10.1097/ta.0000000000004229","url":null,"abstract":"The contribution of the endothelium to trauma-induced coagulopathy has not been thoroughly investigated in injured children.","PeriodicalId":501845,"journal":{"name":"The Journal of Trauma and Acute Care Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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