Journal of Lower Genital Tract Disease最新文献_第9页

Distribution and Severity of Cervical Intraepithelial Neoplasia in Women With Different Human Papillomavirus: An Analysis From Liaoning Province of Northeastern China. 不同人类乳头瘤病毒女性宫颈上皮内瘤变的分布和严重程度：来自中国东北辽宁省的分析。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-05-06 DOI: 10.1097/LGT.0000000000000821

Xin Wei, Yi-Hang Zhou, Peng Chen

{"title":"Distribution and Severity of Cervical Intraepithelial Neoplasia in Women With Different Human Papillomavirus: An Analysis From Liaoning Province of Northeastern China.","authors":"Xin Wei, Yi-Hang Zhou, Peng Chen","doi":"10.1097/LGT.0000000000000821","DOIUrl":"10.1097/LGT.0000000000000821","url":null,"abstract":"Objective: Persistent infection with high-risk human papillomavirus (HPV) is a key contributor to cervical intraepithelial neoplasia (CIN), but the relation between high-risk HPV genotypes and the location of CIN lesions remains unclear. The aims of this study were to investigate the most frequent biopsy site of CIN lesions in women with different HPV infection and to analyze the biopsy times, CIN frequency, and the clustering of CIN frequency based on 12-o'clock sites and cervical quadrant locations.Materials and method: We conducted a retrospective study of HPV detection and genotyping at the virology department of our hospital. Colposcopy exams were performed by specialists according to a standardized protocol, and all visually abnormal areas were further biopsied. Pearson chi-squared tests and cluster analyses were implemented to analyze the data.Results: Among 1,381 women enrolled in this study, 933 cases infected with HPV. HPV16, HPV58, and HPV18 were the most common genotypes. The most frequent biopsy site was the 6 o'clock position. The highest frequency of high-grade CIN findings in single-genotype HPV groups was the 6 o'clock position and that for multiple-genotype HPV group was the 12 o'clock location. All CIN clusters were found in the 6 and 12 o'clock biopsy sites, except in the HPV18 group. Quadrant 2 and 4 were clustered in most groups.Conclusions: The 6 and 12 o'clock sites in cervical quadrant 2 and 4 should be targeted during cervical biopsy procedures. These findings can provide clinicians with specific recommendations on the optimal site for CIN biopsy when considering the HPV genotype.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"231-239"},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fanconi Anemia Complicated by Cervical Precancer, Vulvar, and Oral Squamous Cell Cancer. 宫颈癌前病变、外阴癌和口腔鳞状细胞癌并发范可尼贫血症。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000809

Tania Day, Lilia Stuart, Yvette Ius, Gholamreza Haqshenas, Suzanne M Garland, James Scurry

引用次数: 0

Deep Learning Diagnostic Classification of Cervical Images to Augment Colposcopic Impression. 对宫颈图像进行深度学习诊断分类，以增强阴道镜印象。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI: 10.1097/LGT.0000000000000815

André Aquilina, Emmanouil Papagiannakis

{"title":"Deep Learning Diagnostic Classification of Cervical Images to Augment Colposcopic Impression.","authors":"André Aquilina, Emmanouil Papagiannakis","doi":"10.1097/LGT.0000000000000815","DOIUrl":"10.1097/LGT.0000000000000815","url":null,"abstract":"Objective: A deep learning classifier that improves the accuracy of colposcopic impression.Methods: Colposcopy images taken 56 seconds after acetic acid application were processed by a cervix detection algorithm to identify the cervical region. We optimized models based on the SegFormer architecture to classify each cervix as high-grade or negative/low-grade. The data were split into histologically stratified, random training, validation, and test subsets (80%-10%-10%). We replicated a 10-fold experiment to align with a prior study utilizing expert reviewer analysis of the same images. To evaluate the model's robustness across different cameras, we retrained it after dividing the dataset by camera type. Subsequently, we retrained the model on a new, histologically stratified random data split and integrated the results with patients' age and referral data to train a Gradient Boosted Tree model for final classification. Model accuracy was assessed by the receiver operating characteristic area under the curve (AUC), Youden's index (YI), sensitivity, and specificity compared to the histology.Results: Out of 5,485 colposcopy images, 4,946 with histology and a visible cervix were used. The model's average performance in the 10-fold experiment was AUC = 0.75, YI = 0.37 (sensitivity = 63%, specificity = 74%), outperforming the experts' average YI of 0.16. Transferability across camera types was effective, with AUC = 0.70, YI = 0.33. Integrating image-based predictions with referral data improved outcomes to AUC = 0.81 and YI = 0.46. The use of model predictions alongside the original colposcopic impression boosted overall performance.Conclusions: Deep learning cervical image classification demonstrated robustness and outperformed experts. Further improved by including additional patient information, it shows potential for clinical utility complementing colposcopy.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"224-230"},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awards Presented as Part of the ASCCP 2024 Scientific Meeting on Anogenital & HPV-Related Diseases. ASCCP 2024年肛门生殖器和人乳头瘤病毒相关疾病科学会议颁奖。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000824

引用次数: 0

Dequalinium Chloride for the Treatment of Vulvovaginal Infections: A Systematic Review and Meta-Analysis: Erratum. 用于治疗外阴阴道感染的氯地奎灵：系统回顾与元分析》：勘误。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000823

引用次数: 0

Psychosocial Factors Associated With Vulvodynia. 与外阴炎相关的社会心理因素

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-05-02 DOI: 10.1097/lgt.0000000000000822

Janice F Queiroz, Antonio C Q Aquino, Ayane C A Sarmento, Beatriz B Siqueira, Heitor D Medeiros, Megan L Falsetta, Tracey Maurer, Ana Katherine Gonçalves

引用次数: 0

Time Differences From Abnormal Cervical Cancer Screening to Colposcopy Between Insurance Statuses. 不同保险状况下从宫颈癌筛查异常到阴道镜检查的时间差异。

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-05-02 DOI: 10.1097/lgt.0000000000000812

Sonia Khurana, Isaiah Smolar, Leslie Warren, Jessica Velasquez, Elianna Kaplowitz, Jeanette Rios, Adriana Pero, Harley Roberts, Mackenzie Mitchell, Ceyda Oner, Cynthia Abraham

引用次数: 0

A Scoping Review of Complementary and Alternative Medicine for Human Papillomavirus Infections and Cervical Dysplasia. 针对人类乳头瘤病毒感染和宫颈发育不良的补充和替代医学的范围界定综述》（A Scoping Review of Complementary and Alternative Medicine for Human Papillomavirus Infections and Cervical Dysplasia）。

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-05-02 DOI: 10.1097/lgt.0000000000000806

Caroline J Walsh, Julie C Friedman, Christine Conageski, Christi Piper

引用次数: 0

Enduring Consensus Guidelines for Cervical Cancer Screening and Management: Introduction to the Scope and Process. 宫颈癌筛查和管理持久共识指南》：范围和过程介绍。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-04-01 Epub Date: 2024-03-02 DOI: 10.1097/LGT.0000000000000804

Nicolas Wentzensen, Francisco Garcia, Megan A Clarke, L Stewart Massad, Li C Cheung, Didem Egemen, Richard Guido, Warner Huh, Debbie Saslow, Robert A Smith, Elizabeth R Unger, Rebecca B Perkins

{"title":"Enduring Consensus Guidelines for Cervical Cancer Screening and Management: Introduction to the Scope and Process.","authors":"Nicolas Wentzensen, Francisco Garcia, Megan A Clarke, L Stewart Massad, Li C Cheung, Didem Egemen, Richard Guido, Warner Huh, Debbie Saslow, Robert A Smith, Elizabeth R Unger, Rebecca B Perkins","doi":"10.1097/LGT.0000000000000804","DOIUrl":"10.1097/LGT.0000000000000804","url":null,"abstract":"Objectives: The Enduring Consensus Cervical Cancer Screening and Management Guidelines (Enduring Guidelines) effort is a standing committee to continuously evaluate new technologies and approaches to cervical cancer screening, management, and surveillance.Methods and results: The Enduring Guidelines process will selectively incorporate new technologies and approaches with adequate supportive data to more effectively improve cancer prevention for high-risk individuals and decrease unnecessary procedures in low-risk individuals. This manuscript describes the structure, process, and methods of the Enduring Guidelines effort. Using systematic literature reviews and primary data sources, risk of precancer will be estimated and recommendations will be made based on risk estimates in the context of established risk-based clinical action thresholds. The Enduring Guidelines process will consider health equity and health disparities by assuring inclusion of diverse populations in the evidence review and risk assessment and by developing recommendations that provide a choice of well-validated strategies that can be adapted to different settings.Conclusions: The Enduring Guidelines process will allow updating existing cervical cancer screening and management guidelines rapidly when new technologies are approved or new scientific evidence becomes available.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"117-123"},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between Childhood Sexual Abuse, Obesity, and Vulvodynia in Adulthood. 童年性虐待、肥胖与成年后外阴炎之间的关系

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI: 10.1097/LGT.0000000000000799

Rachel B Blaustein, Christine A Parker, Hope K Haefner, Barbara D Reed, Jessica K Haefner, Kathryn C Welch

{"title":"Relationship Between Childhood Sexual Abuse, Obesity, and Vulvodynia in Adulthood.","authors":"Rachel B Blaustein, Christine A Parker, Hope K Haefner, Barbara D Reed, Jessica K Haefner, Kathryn C Welch","doi":"10.1097/LGT.0000000000000799","DOIUrl":"10.1097/LGT.0000000000000799","url":null,"abstract":"Objective: The aim of the study is to assess the relationship between childhood sexual abuse, obesity, and vulvodynia among adult women participating in a population-based longitudinal vulvodynia study.Materials and methods: Surveys assessed health status, diagnoses, risk factors, and screening test outcomes for women with vulvodynia. Associations between childhood sexual abuse (CSA) and obesity, CSA and vulvodynia, and obesity and vulvodynia were investigated. A multivariate model was used to determine if obesity mediates and/or modifies the relationship between CSA and vulvodynia.Results: Of 2,277 women participating in the study, 1,647 completed survey data on CSA at 18 months, body mass index at 24 months, and vulvodynia over the first 54 months of the survey. Mean age was 50.9 ± 15.8 years. Overall, race and ethnicity were 77.4% White, 15.7% Black, 2.4% Hispanic, and 4.5% other. Five hundred thirty-nine participants (32.7%) were obese (body mass index >30) and 468 (28.4%) were overweight. Physical CSA before age of 18 years was reported by 20.0% ( n = 329). During the study, 22.0% ( n = 362) screened positive for vulvodynia on one or more surveys. After controlling for demographic variables, both obesity and screening positive for vulvodynia were associated with a history of CSA before age of 18 years ( p = .013 and p < .001, respectively), but obesity was not associated with screening positive for vulvodynia ( p = .865). In addition, multivariate analysis indicated no mediation of the CSA/vulvodynia relationship by obesity.Conclusions: Although obesity and vulvodynia were independently associated with a history of CSA, obesity did not mediate or modify the relationship between CSA and vulvodynia in adulthood.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"160-163"},"PeriodicalIF":3.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0