The Egyptian Journal of Otolaryngology最新文献

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Never too young for a salivary gland carcinoma ex-pleomorphic adenoma 唾液腺癌前乳头状腺瘤永远不会太年轻
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-25 DOI: 10.1186/s43163-024-00575-8
Ahmad Muizzuddin Ahmad Fuad, Lum Sai Guan, Mohd Razif Mohamad Yunus
{"title":"Never too young for a salivary gland carcinoma ex-pleomorphic adenoma","authors":"Ahmad Muizzuddin Ahmad Fuad, Lum Sai Guan, Mohd Razif Mohamad Yunus","doi":"10.1186/s43163-024-00575-8","DOIUrl":"https://doi.org/10.1186/s43163-024-00575-8","url":null,"abstract":"Carcinoma ex-pleomorphic adenoma (CXPA) can either arise primarily as a de novo or from the malignant transformation of a benign pleomorphic adenoma (PA). CXPA mostly occurs in adults aged 50 to 70 years; hence, the occurrence of CXPA in younger ages is not common. We report a 27-year-old female who had a history of submandibulectomy for pleomorphic adenoma, and presented with recurrent left submandibular swelling for 4 months. The mass was rapidly increasing in size and was associated with occasional throbbing pain. Examination showed a multilobulated, firm left submandibular swelling with no overlying skin changes. FNAC was performed twice, by conventional and ultrasound-guided techniques, and both concluded as benign salivary gland tumours. CT scan and MRI revealed a well-demarcated tumour with an area of necrosis within, with no obvious invasion into surrounding soft tissue and no significant lymphadenopathy. Having high suspicion of a malignant transformation, the tumour was resected with a concurrent modified radical neck dissection. The histopathological examination confirmed a carcinoma ex-pleomorphic adenoma with the myoepithelial malignant component. The patient subsequently received adjuvant radiotherapy. This case demonstrated that CXPA, although rare, can occur in young adults. Pre-operative FNAC and radiological imaging may mimic a pleomorphic adenoma. The presence of recurrent tumours with rapid growth should alarm the clinician about a possible malignant transformation of a benign parotid tumour.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of COVID-19 on peripheral and central hearing abilities COVID-19 对外周和中枢听力能力的影响
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00567-8
Rohit Bhattacharyya, Sushmitha S. Upadhya, Prashanth Prabhu
{"title":"Effect of COVID-19 on peripheral and central hearing abilities","authors":"Rohit Bhattacharyya, Sushmitha S. Upadhya, Prashanth Prabhu","doi":"10.1186/s43163-024-00567-8","DOIUrl":"https://doi.org/10.1186/s43163-024-00567-8","url":null,"abstract":"COVID-19 has caused various implications on physical and mental health of human beings. It included several symptoms involving the auditory vestibular system. This study aims to investigate the impact of active COVID-19 infection on central and peripheral auditory pathways. Two groups of subjects were involved in the research: Group I consisted of 45 individuals with no history of COVID-19, while Group II included 41 individuals who were diagnosed with COVID-19 through RT-PCR testing. The audiological battery used in this study included Pure tone audiometry, Digit in Noise test, Dichotic CV test, and Pitch pattern test, all of which were administered online. Testing was conducted in two phases for both groups. Phase 1 testing took place within the first 7 days of a positive RT-PCR result, while Phase 2 testing occurred within a week of a negative RT-PCR test. Additionally, participants completed a questionnaire to provide information on general health conditions and their otological symptoms. The results from Phase 1 testing revealed that Group II exhibited statistically lower scores in all the audiological tests compared to Group I (control group). However, during Phase 2 testing, this significant difference was no longer observed between both groups. Based on the findings, it can be inferred that the audiological pathway was compromised during the active infection stage of COVID-19. Therefore, this study highlights changes in performance concerning tests that assess the central auditory system during the infection period. SH/IRB/RP/24. Registered 12 January 2021.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of Arabic Language Sample Analysis as a screening tool in kindergarten Egyptian bilingual children 将阿拉伯语抽样分析法用作幼儿园埃及双语儿童的筛查工具
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00569-6
Dalia Mostafa Osman, Asmaa Ahmed Abdel Hamid, Samar Maged, Aisha Fawzy Abdel Hady
{"title":"The use of Arabic Language Sample Analysis as a screening tool in kindergarten Egyptian bilingual children","authors":"Dalia Mostafa Osman, Asmaa Ahmed Abdel Hamid, Samar Maged, Aisha Fawzy Abdel Hady","doi":"10.1186/s43163-024-00569-6","DOIUrl":"https://doi.org/10.1186/s43163-024-00569-6","url":null,"abstract":"Language sample analysis is a naturalistic method used for measuring child’s expressive language abilities. It is used in case of difficulty in direct interaction in remote places or pandemics. The aim of this study is to evaluate the use of a language sample analysis as an easy applicable screening tool for narrative ability in kindergarten Egyptian bilingual children in order to reach a better understanding of their language profile. Subjects and methods: 150 bilingual Egyptian preschool male and female children exposed to Arabic and English languages were included and divided into two groups according to their age. All were subjected to the BEA-LSA narration assessment including macrostructure, microstructure items, and conversation assessment including verbal and nonverbal items. The results revealed that bilingual children showed better performance in English than Arabic in most of the narration and conversation tasks. However, there was equal development between both age groups in English language regarding temporality, connectives, and reference clarity. The older age group showed higher code switching than younger age group and code switching occurred more from Arabic to English language. Both age groups bilingual children showed better frequency of words and mean length of utterance in narration. While in conversation, both age groups showed better type token ratio. Language sample analysis showed good test–retest reliability. Language sample analysis could identify the characteristic profile of bilingual kindergarten Egyptian children and was a reliable method to analyze both narration and conversation skills of bilingual children.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of music listening time with headphones on hearing thresholds among the young population 用耳机听音乐的时间对年轻人听力阈值的影响
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00574-9
Hülya Osmanoğlu, Handan Turan Dizdar, Azize Arzu Koçyiğit
{"title":"The effects of music listening time with headphones on hearing thresholds among the young population","authors":"Hülya Osmanoğlu, Handan Turan Dizdar, Azize Arzu Koçyiğit","doi":"10.1186/s43163-024-00574-9","DOIUrl":"https://doi.org/10.1186/s43163-024-00574-9","url":null,"abstract":"Today, young people who listen to loud music, especially through headphones, are at an extremely high risk of noise-induced hearing loss. The aim of this study was to investigate how young people’s listening habits affect their hearing thresholds. A total of 88 young adults between the ages of 18 and 25 took part in the study, 44 of whom listened to music through headphones while the others did not. The control group was exposed to white noise at 55–65 dB with the Interacoustic AC 40 Hybrid Audiometer, and people who did not use headphones and said they were not exposed to higher levels of sound than the given sample were included in the study. Participants were given a survey to assess their music listening preferences. One hundred twenty-five to 18,000 Hz air conduction hearing thresholds were assessed for all participants. When the pure tone thresholds of the groups were compared, the independent t-test showed that the thresholds of the study group were significantly worse than those of the control group. Bilaterally in the 4000 Hz band and for the left ear in the 6000 Hz band (p < 0.05). There were also significant differences between the groups in the 14,000 Hz and 16,000 Hz bands in the right ear and the 14,000 Hz, 16,000 Hz, and 18,000 Hz bands in the left ear (p < 0.05). Twenty-two participants reported listening to music at a high level, 16 participants at a moderate level, and 6 participants at a very high level. Although the hearing thresholds of the study group were worse than those of the control group in the 4000 Hz, 6000 Hz, 14,000 Hz, 16,000 Hz, and 18,000 Hz bands, the hearing thresholds of both groups were still within the hearing range and could be classified as normal. It should be remembered that hearing will deteriorate if a person listens to loud or very loud music continuously through headphones. The public, especially young people, should be made aware of this.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimum stimulus for eliciting masseter vestibular-evoked myogenic potential: a comparative exploration with three different acoustic stimuli 激发颌间肌前庭诱发肌原电位的最佳刺激:三种不同声音刺激的比较研究
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-23 DOI: 10.1186/s43163-024-00570-z
Aishwarya Nagarajan, Vinayagar Pazhani Thirusangu, Gunasekaran Mohanlal, Sujeet Kumar Sinha
{"title":"Optimum stimulus for eliciting masseter vestibular-evoked myogenic potential: a comparative exploration with three different acoustic stimuli","authors":"Aishwarya Nagarajan, Vinayagar Pazhani Thirusangu, Gunasekaran Mohanlal, Sujeet Kumar Sinha","doi":"10.1186/s43163-024-00570-z","DOIUrl":"https://doi.org/10.1186/s43163-024-00570-z","url":null,"abstract":"To compare the EMG rectified amplitude, absolute latencies, interpeak interval, and Interaural asymmetry parameters of masseter vestibular-evoked myogenic potential (mVEMP) elicited using clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. Twenty-five young healthy adults in the age range of 18–27 years participated for the study. mVEMP was recorded using three different acoustic stimuli i.e., clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. mVEMP was recorded at an intensity of 125 dB peSPL with 5.1/s repetition rate. The potentials were recorded ipsilaterally using zygomatic electrode montage and were filtered between 0.1 and 3000 Hz. EMG rectification of the responses was made prior to analysis. The latencies of P1 and N1 were significantly earlier for chirps then followed by click and tone bursts. The EMG rectified amplitude was significantly larger for the potentials obtained using chirps followed by tone bursts and then the clicks. Masseter VEMP obtained using chirps had significantly larger interpeak interval than tone bursts and clicks. The mean amplitude asymmetry ratio was greater in the potentials obtained using chirps than the other two stimuli. The present study reveals that 500 Hz NB CE-chirps tend to produce mVEMP with larger response amplitude and earlier latencies and thus are considered better and constructive stimuli compared to clicks and tone bursts.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Speech auditory brainstem responses (s-ABRs) as a new approach for the assessment of speech sounds coding 语音听觉脑干反应(s-ABRs)是评估语音编码的一种新方法
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-22 DOI: 10.1186/s43163-024-00562-z
Hagar Ahmed Elsayed, Ebtessam Hamed Nada, Dalia Helal Galhoum, Nadia Mohamed Elnabtity
{"title":"Speech auditory brainstem responses (s-ABRs) as a new approach for the assessment of speech sounds coding","authors":"Hagar Ahmed Elsayed, Ebtessam Hamed Nada, Dalia Helal Galhoum, Nadia Mohamed Elnabtity","doi":"10.1186/s43163-024-00562-z","DOIUrl":"https://doi.org/10.1186/s43163-024-00562-z","url":null,"abstract":"The evoked auditory brainstem response (EABR) is an objective electrophysiological test used to assess the brainstem’s auditory neural activity. Speech ABR (s-ABR) testing using verbal stimuli gives more important details about how the brainstem processes speech inputs which enables the detection of auditory processing impairments that do not manifest in click-provoked ABR. The use of speech syllables in the s-ABR reveals an important brainstem function that plays a crucial part in reading development and phonologic achievement which is an assessment of speech syllables. The syllable /da/ is often utilized in s-ABR measurement being a global syllable that can be tested in many nations with effective experimental confidence. The speech ABR is an objective, unbiased, quick test. It can be used to differentiate between many conditions such as auditory processing disorders (APD), specific language impairment (SLI), and children with academic challenges.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between tympanometric findings and adenoid hypertrophy among children without hearing loss in tertiary care hospital 三级医院无听力损失儿童的鼓室测量结果与腺样体肥大之间的相关性
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-22 DOI: 10.1186/s43163-024-00568-7
K. P. Basavaraju, S. K. Ranjani, V. Sri Vaibhava, Sushmita Sulhyan
{"title":"Correlation between tympanometric findings and adenoid hypertrophy among children without hearing loss in tertiary care hospital","authors":"K. P. Basavaraju, S. K. Ranjani, V. Sri Vaibhava, Sushmita Sulhyan","doi":"10.1186/s43163-024-00568-7","DOIUrl":"https://doi.org/10.1186/s43163-024-00568-7","url":null,"abstract":"Adenoid hyperplasia is a common cause of nasal obstruction in children. Chronic infection and hypertrophy result in mouth breathing, snoring, sleep apnoea, hyponasality, sinusitis, and otitis media with effusion (OME). Some children with adenoid hypertrophy have OME in spite of having no complaints of hearing loss. Untreated OME may adversely affect the speech and intellectual development of the child. Aim To determine whether there is a correlation between tympanometric findings and various radiological and endoscopic grades of adenoid hypertrophy. To propose a combination of radiological and/or endoscopic assessment of adenoids and tympanometry as a screening program in patients with suspicion of adenoid hypertrophy. Materials and methods One hundred children, presenting with one or more complaints of upper airway obstruction (UAO), suggestive of adenoid hypertrophy, without a history of hearing loss, to the OPD, were chosen for the study. X-ray nasopharynx soft tissue lateral view was done for all patients. Rigid diagnostic nasal endoscopy with 0° endoscope was conducted in only children who were cooperative and with parental consent. Tympanometry was carried out for all patients and plotted on tympanograms. Results In our study, the mean age of children is 9.43 ± 2.430 years with gender distribution being 57% males and 43% females. The majority of children tend to present with nasal obstruction (100%), mouth breathing (83%), and snoring (56%). On both radiological and endoscopic evaluation of adenoids and correlation with tympanogram, a significantly higher number of patients with Grade 1 adenoids have a type A curve, while a significantly higher number of grade 3 adenoids patients have a type B curve and type C is significantly more prevalent in grade 2 and grade 4 adenoids (p < 0.05). Conclusion In our study, adenoid size as measured from both adenoid X-ray and adenoid endoscopy, showed a significant association with the presence of middle ear effusion and also with eustachian tube dysfunction. This helps in early detection, prior to the development of hearing loss, making it easy to plan early intervention, and curbing the possibility of aggravation of the condition and occurrence of complications.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic upper third molar embedded in a dentigerous cyst of the maxillary sinus: a case report and literature review 嵌入上颌窦齿槽囊肿的异位上第三磨牙:病例报告和文献综述
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-19 DOI: 10.1186/s43163-024-00564-x
Raid M. Al-Ani, Tahrir N. Aldelaimi, Afrah A. Khalil, Suzan M. Abdulkareem
{"title":"Ectopic upper third molar embedded in a dentigerous cyst of the maxillary sinus: a case report and literature review","authors":"Raid M. Al-Ani, Tahrir N. Aldelaimi, Afrah A. Khalil, Suzan M. Abdulkareem","doi":"10.1186/s43163-024-00564-x","DOIUrl":"https://doi.org/10.1186/s43163-024-00564-x","url":null,"abstract":"Dentigerous cysts are the second most common form of a developmental cyst. These cysts might be the cause of ectopic teeth. Dentigerous cysts associated with ectopic teeth in the maxillary sinus are seldom seen in clinical practice. We reported a 23-year-old woman who presented with nasal obstruction and facial pain on the left side 4 months ago. Three courses of antibiotics and analgesia were prescribed for her without improving the presenting features. Furthermore, extraction of the left upper second premolar and second molar, but the condition persisted. An orthopantogram and computerized tomography scan revealed the ectopic position of the left third upper molar tooth, which was embedded in a cystic lesion occupying the whole maxillary sinus. Removal of the cystic lesion with the ectopic tooth was performed with a Caldwell-Luc procedure. The histopathological evaluation confirmed the diagnosis of a dentigerous cyst. The presenting symptoms were resolved following surgery with no intra- or postoperative complications. We are reporting another case of a dentigerous cyst occupying the whole left maxillary sinus with an ectopic left third upper molar tooth. Reporting such a case will enrich the literature regarding this rare clinical entity.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139499509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of short-term phonatory outcomes in primary cases of early glottic cancer treated with radiotherapy versus laser surgery 放疗与激光手术治疗早期声门癌原发病例短期发音效果比较研究
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-18 DOI: 10.1186/s43163-024-00565-w
Devender Kumar Gupta, Mahesh Ravunnikutty, Sanajeet Kumar Singh, Rajeev Chugh, Ravi Roy, Sunil Goyal, Himanshu Swami, Bhaumik Patel, Sneha Yadav, Sween Banger
{"title":"A comparative study of short-term phonatory outcomes in primary cases of early glottic cancer treated with radiotherapy versus laser surgery","authors":"Devender Kumar Gupta, Mahesh Ravunnikutty, Sanajeet Kumar Singh, Rajeev Chugh, Ravi Roy, Sunil Goyal, Himanshu Swami, Bhaumik Patel, Sneha Yadav, Sween Banger","doi":"10.1186/s43163-024-00565-w","DOIUrl":"https://doi.org/10.1186/s43163-024-00565-w","url":null,"abstract":"Early-stage glottic carcinomas can be treated with either laser surgery or radiotherapy. Both approaches have demonstrated similar cure rates. However, the question of which modality is superior in terms of voice outcomes remains a topic of debate. In our study, we conducted a comparison of short-term phonatory outcomes in patients with primary early glottic cancer who underwent treatment using both modalities. We assessed these outcomes using videostroboscopy and voice analysis software at three time points: immediately following treatment, at 1 month, and at 3 months post-treatment. Voice analysis revealed that laser surgery had a more favorable immediate effect compared to radiotherapy in parameters such as jitter, shimmer, harmonics-to-noise ratio, and fundamental frequency. However, at the 3-month post-treatment mark, both treatment modalities demonstrated similar effects. Additionally, both modalities had comparable effects on maximum phonation time. Videostroboscopy observations showed that mucosal wave forms were more prominent immediately after laser surgery and gradually improved following radiotherapy. Furthermore, patients with incomplete glottic closure experienced recovery after both treatment modalities. Based on the results, there are better outcomes immediately following LS compared to RT. However, after a 3-month period, the outcomes of both treatment modalities become comparable. The treating physicians must consider various factors such as complications, patient-specific considerations, treatment costs, and duration to make informed decisions. A personalized approach considering the individual patient’s circumstances is crucial in achieving optimal results in the management of T1 laryngeal cancer.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139499514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin D profile in autism spectrum disorder children and its relation to the disease severity 自闭症谱系障碍儿童的维生素 D 含量及其与疾病严重程度的关系
The Egyptian Journal of Otolaryngology Pub Date : 2024-01-18 DOI: 10.1186/s43163-024-00573-w
Amira Mansour, Ayman Amer, Ali Sobh, Maysaa Zaki, Tamer Abou-Elsaad
{"title":"Vitamin D profile in autism spectrum disorder children and its relation to the disease severity","authors":"Amira Mansour, Ayman Amer, Ali Sobh, Maysaa Zaki, Tamer Abou-Elsaad","doi":"10.1186/s43163-024-00573-w","DOIUrl":"https://doi.org/10.1186/s43163-024-00573-w","url":null,"abstract":"The study aimed to investigate whether vitamin D deficiency is a common finding in autism spectrum disorder (ASD) children and whether such deficiency is related to ASD severity and language age or not. A cross-sectional observational study was conducted on ASD children aged 2-6 years. The participants were 80 Egyptian children with ASD. All participants were assessed using DSM-V, the Childhood Autism Rating Scale (CARS), language assessment, and assessment of serum vitamin D using ADVIA Centaur Vit D assay. About 63.8% of ASD children have vitamin D insufficiency, 28.8 % have vitamin D deficiency, and 7.4% have normal serum levels. No correlation was found between serum vitamin D and language age (r = -0.085, P = 0.451), DSM 5 severity levels (r = 0.015, P= 0.894), and CARS scores (r= 0.075, P= 0.511). ASD children have lower serum vitamin D levels, which may be one of the environmental factors contributing to ASD development in genetically susceptible individuals, and its correction may be helpful as adjuvant therapy for ASD.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"297 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139499849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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