Clinical Medicine And Health Research Journal最新文献_第2页

The Association between Cholesterol Ratio and Viral load Among HIV individuals on Antiretroviral Therapy at a Tertiary Hospital in Zambia 赞比亚一家三级医院接受抗逆转录病毒疗法的艾滋病毒感染者的胆固醇比率与病毒载量之间的关系

Clinical Medicine And Health Research Journal Pub Date : 2024-02-18 DOI: 10.18535/cmhrj.v4i1.309

Christopher Nyirenda, Phinehas K. Kunda, Sebastian Chinkoyo, Mabvuto Zulu, K. Gondwe

{"title":"The Association between Cholesterol Ratio and Viral load Among HIV individuals on Antiretroviral Therapy at a Tertiary Hospital in Zambia","authors":"Christopher Nyirenda, Phinehas K. Kunda, Sebastian Chinkoyo, Mabvuto Zulu, K. Gondwe","doi":"10.18535/cmhrj.v4i1.309","DOIUrl":"https://doi.org/10.18535/cmhrj.v4i1.309","url":null,"abstract":"Objective: To examine the association between cholesterol ratio and viral load among HIV positive individuals receiving antiretroviral therapy (cART)\u0000Design and Methods: A retrospective cohort study was conducted at the Ndola Teaching Hospital in Zambia, focusing on individuals with HIV who were receiving care at the outpatient department. Through an in-depth secondary analysis of an existing database, we explored the relationship between cholesterol ratio and viral load in HIV-positive individuals undergoing antiretroviral therapy.\u0000Using a quantitative-methods approach, we selected and processed data from the database to address our research question. The study records included patient subjects initiating and on cART within 12 months and were stratified into 3 groups namely: group A optimal normal (cholesterol ratio between 1 and 3.5), group B high normal (cholesterol ratio between 3.5 and 5) and group C, high cholesterol ratio (cholesterol ration above 5). STATA was used for statistical analysis.\u0000Results: A total of 174 participants were included in the study analysis, with 61% (107) being female and 39% (67) male. Lipid profiles fell within normal ranges for both genders. The median cholesterol ratio was [3.16 (2.93, 3.40)] and total cholesterol was [3.86 (3.02, 4.62)]. The median HDL-c concentration was higher in males [1.4 (1.21, 1.55)] than females [1.33(1.13, 1.51)]. The median viral load in females was [355; (20, 6770)] and in males, [254 (23, 2694)] with a p=0.84. The study identified an inverse relation between cholesterol ratio and viral load, but this association did not reach statistical significance.\u0000Conclusion: The study population predominantly exhibited normal cholesterol ratios, and although a potential inverse relationship with viral load was indicated, statistical significance was not established.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"6 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Evaluation of Factors Impeding Adherence to Established Hand Hygiene Protocols Among Medical Students at Three University Teaching Hospitals in Zambia 对妨碍赞比亚三所大学教学医院医学生遵守既定手部卫生规范的因素进行评估

Clinical Medicine And Health Research Journal Pub Date : 2024-02-18 DOI: 10.18535/cmhrj.v4i1.310

Christopher Nyirenda, Toshiki M Kucheba, Sebastian Chinkoyo, Mabvuto Zulu, K. Gondwe

{"title":"An Evaluation of Factors Impeding Adherence to Established Hand Hygiene Protocols Among Medical Students at Three University Teaching Hospitals in Zambia","authors":"Christopher Nyirenda, Toshiki M Kucheba, Sebastian Chinkoyo, Mabvuto Zulu, K. Gondwe","doi":"10.18535/cmhrj.v4i1.310","DOIUrl":"https://doi.org/10.18535/cmhrj.v4i1.310","url":null,"abstract":"Objective: To assess the obstacles affecting compliance with established hand hygiene protocols among medical students at university teaching hospitals\u0000Design and Methods: The study was conducted at Ndola Teaching Hospital, Kitwe Teaching Hospital, Copperbelt University Dental Clinic, and Arthur Davidson Children’s Hospital, serving as training sites for medical students at Copperbelt University School of Medicine in Zambia. The target population were Bachelor of Medicine and Bachelor of Surgery (MBChB) and Bachelor of Dental Surgery (BDS) students in their clinical years. The research employed a cross-sectional descriptive questionnaire-based study to evaluate the factors hindering compliance to hand hygiene protocols. A non-probability quota sampling technique was applied, stratifying participants by clinical year for a comprehensive representation.\u0000Results: The sample was derived from a population of 497 students, using EpiInfo Build Number 1.4.3 at a confidence level of 95%, an expected value of 50% and a confidence limit of 5%. A required sample of 217 was needed and factoring in an assumed response rate of 70%, at least 300 questionnaires were distributed in which there was a response rate of 81% resulting in a sample size of 244. Lack of facilities was the major self-reported factor limiting compliance at 50.4%, lack of knowledge and facilities at 17.2%, lack of knowledge at 10.2% and a personal failure to adherence at 9.8% while 12.3% reported no factors.\u0000Conclusion: A multi-faceted approach that combines improvements in facilities, educational initiatives, and addressing individual attitudes is essential for enhancing hand hygiene practices. By addressing the identified barriers comprehensively, healthcare settings and individuals can collectively contribute to effective infection prevention.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"4 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Series Study on Recovery of Left Ventricle Systolic Function After Percutaneous Coronary Intervention In ST-Segment Elevation Myocardial Infarction Patients at FMIC Hospital in Kabul, Afghanistan. 阿富汗喀布尔 FMIC 医院 ST 段抬高心肌梗死患者经皮冠状动脉介入治疗后左心室收缩功能恢复的病例系列研究。

Clinical Medicine And Health Research Journal Pub Date : 2024-01-10 DOI: 10.18535/cmhrj.v4i1.299

Dr. Abdul Ghafoor Zarmalwal, Dr. Tazeen Saeed Ali, Dr. Sher Ahmad, Dr. Ihsanullah Darmal, Dr. Ahmad Khan

{"title":"Case Series Study on Recovery of Left Ventricle Systolic Function After Percutaneous Coronary Intervention In ST-Segment Elevation Myocardial Infarction Patients at FMIC Hospital in Kabul, Afghanistan.","authors":"Dr. Abdul Ghafoor Zarmalwal, Dr. Tazeen Saeed Ali, Dr. Sher Ahmad, Dr. Ihsanullah Darmal, Dr. Ahmad Khan","doi":"10.18535/cmhrj.v4i1.299","DOIUrl":"https://doi.org/10.18535/cmhrj.v4i1.299","url":null,"abstract":"Background\u0000Left ventricle dysfunction is the most recurrent consequence of ST-elevated myocardial infarction, and still, it is a powerful predictor of mortality. The percutaneous coronary intervention of the culprit artery disease in acute coronary syndrome is related to a significant improvement of left ventricle segmental function.\u0000It is a retrospective case series study on a patient population with the diagnosis of ST-elevated myocardial infarction patients who presented to the hospital within 12 hours and underwent percutaneous coronary intervention at the French Medical Institute of Mother and Children Hospital. Data was collected retrospectively from the patient's medical record files and analyzed. We took the patients with Left ventricle dysfunction on echocardiography on the first presentation before percutaneous coronary intervention and saw the left ventricle function after three months of follow-up.\u0000We reviewed the charts of 102 patients (78.4% male and 21.6% female) with a diagnosis of St-elevated myocardial infarction who presented within 12 hours of chest pain. Of 102 patients, 55.9% had hypertension, 21.6% diabetes, 22.5% dyslipidemia, and 19.6% history of smoking, and their mean age was 58.11 ± 11.993 years. We noticed that percutaneous coronary intervention led to significant left ventricle dysfunction improvement in the patient population with ST-elevated myocardial infarction who presented within 12 hours of chest pain.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139439076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outline for Empathy-Based Medical Education 移情医学教育大纲

Clinical Medicine And Health Research Journal Pub Date : 2024-01-02 DOI: 10.18535/cmhrj.v4i1.297

Vijayaraghavan Padmanabhan

{"title":"Outline for Empathy-Based Medical Education","authors":"Vijayaraghavan Padmanabhan","doi":"10.18535/cmhrj.v4i1.297","DOIUrl":"https://doi.org/10.18535/cmhrj.v4i1.297","url":null,"abstract":"Empathy has been recognized in recent years to play a central role for the successful practice of medicine. Hence, developing empathetic skills needs to be the underlying objective during the training of undergraduate medical students as well as in continuous education of health professionals. However, during the process of medical education, the quality of empathy that is naturally present within the student has been found to decline. The task is to achieve the process of learning medicine and at the same time preserve and foster the quality of empathy. Spontaneous learning based on one’s own interest, is a form of self-directed learning that taps the student’s sense of curiosity about the problem and concern for the patient. Knowledge is acquired in a case-centered manner. All evaluations to be done through case-based discussions. The textbooks in each subject are to be treated as knowledge repositories for choosing the topics that need to be learnt. The ‘self-directed spontaneous learning’ ensures creativity in approach to problems, optimum utilization of one’s time and avoids stress. The student’s connection with his or her own ‘inner self’ is crucial for a focused and creative mind; therefore, its cultivation through the process of meditation is important. Empathy-based medical education-EBME facilitates the training of doctors who are competent as well as empathetic. Keeping the subjective aspect of education as the base while acquiring the objective aspect, leads to balance between competence and empathy.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"131 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analyzing Short and Medium-Term Morbidity and Mortality in Patients with Heart Failure and Borderline Ejection Fraction (EF: 40-49%). 分析心力衰竭和边缘射血分数（EF：40-49%）患者的中短期发病率和死亡率。

Clinical Medicine And Health Research Journal Pub Date : 2024-01-02 DOI: 10.18535/cmhrj.v4i1.296

I. B. Bencheboub, N. T. Taleb Bendiab, A. Ghalmi, Y.M.S. Cherifi, S. Benkhedda

{"title":"Analyzing Short and Medium-Term Morbidity and Mortality in Patients with Heart Failure and Borderline Ejection Fraction (EF: 40-49%).","authors":"I. B. Bencheboub, N. T. Taleb Bendiab, A. Ghalmi, Y.M.S. Cherifi, S. Benkhedda","doi":"10.18535/cmhrj.v4i1.296","DOIUrl":"https://doi.org/10.18535/cmhrj.v4i1.296","url":null,"abstract":"Introduction: Heart failure with moderately impaired ejection fraction (HFmEF) has garnered increasing attention in recent years. However, understanding this new phenotype, particularly concerning morbidity and mortality, remains limited.\u0000Materials and Methods: A prospective, observational, and single-center study spanning 26 months was conducted on 204 patients with HFmEF selected from 447 patients with chronic heart failure (CHF) categorized based on their left ventricular ejection fraction (LVEF): HF with reduced ejection fraction (HFrEF) if LVEF ≤ 40% (n = 173) and HF with preserved ejection fraction (HFpEF) if LVEF ≥ 50% (n = 70). This study included a detailed evaluation of factors precipitating cardiovascular (CV) death and rehospitalizations in patients with HFmEF.\u0000Results: After a mean follow-up of 431 days in the HFmEF patient group, our results indicated that CV mortality at six months was 2.5%, and at one year, it was 5.9%. Prognostic factors for survival included chronic kidney disease, blood glucose level > 1.4g/l, presence of moderate to severe secondary mitral insufficiency, sphericity index < 1.7, elevated pulmonary vascular resistance, and resistance to diuretic treatment. HF rehospitalization rates at 6 and 12 months were 2.5% and 8.3%, respectively. Predictive factors for HF rehospitalizations included diabetes, hemoglobin level < 13g/dl, left atrial volume > 34 ml/m3-, mitral S-wave < 0.05cm/s, non-improvement of global longitudinal strain, and resistance to diuretic treatment.\u0000Conclusion: This category of HF remains underrecognized and neglected by practitioners, and its prognosis is formidable, especially in the presence of adverse prognostic factors.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"67 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Qualitative Study on Urinary Tract Infections Among Adult Patients in Bost University Hospital, Helmand 关于赫尔曼德省博斯特大学医院成人尿路感染的定性研究

Clinical Medicine And Health Research Journal Pub Date : 2023-12-21 DOI: 10.18535/cmhrj.v3i6.292

Abdul Rahman Arian, Dr. Melanie M. Tidman, Abdul Tawab Khpalwak, Ahmad Khan

{"title":"A Qualitative Study on Urinary Tract Infections Among Adult Patients in Bost University Hospital, Helmand","authors":"Abdul Rahman Arian, Dr. Melanie M. Tidman, Abdul Tawab Khpalwak, Ahmad Khan","doi":"10.18535/cmhrj.v3i6.292","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i6.292","url":null,"abstract":"Urinary tract infections (UTIs) are the leading cause of hospital visits worldwide, significantly impacting patients with underlying illnesses. To effectively manage UTIs, it is essential to understand the causes of these conditions. This study aimed to determine the prevalence of UTIs and identify the contributing factors among adult patients attending Bost University Hospital (BUH). A cross-sectional study involved 1768 patients from the internal medicine department at BUH. Among these patients, 125 (7.07% of total visitors) were diagnosed with UTIs, 108 of whom were interviewed.\u0000The findings revealed that 57 of 108 patients (52.7%) experienced recurrent UTIs. Most diagnosed UTI patients were female (77.7%), and 92 of the 108 participants were married. The participants reported various signs and symptoms, including burning, dysuria, fever, frequency, abdominal pain, cloudy urine, urgency, chills, dribbling, and blood in urine.\u0000The outcomes of this study will provide valuable insights for researchers, policymakers, and public health organizations seeking to address the factors contributing to UTIs. However, it is essential to acknowledge the study's limitations, such as the relatively small sample size and the fact that it was conducted exclusively among patients visiting the outpatient department of BUH's internal medicine department. Although these findings may not represent the general population, they are a starting point for further research.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138951082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-Based Practice in Nursing: A Comprehensive Review 护理中的循证实践：全面回顾

Clinical Medicine And Health Research Journal Pub Date : 2023-12-11 DOI: 10.18535/cmhrj.v3i6.254

Haseena Naz, Nasir Ahmad Ganaie

引用次数: 0

Acute Leukemia in A Young Female Adult Presenting for Care in A Resource Constrained Setting 在资源有限的环境中接受治疗的年轻女性成人的急性白血病

Clinical Medicine And Health Research Journal Pub Date : 2023-12-09 DOI: 10.18535/cmhrj.v3i6.285

Simakando A. Mwizabi, Brian Musuka, Celine Mwape, Audrey Mulenga, Mutale Mweene, Catherine Maliko, G. Maksoud, Mwinsa Chimese, Mabvuto Zulu, Sebastian Chinkoyo, Christopher Nyirenda

{"title":"Acute Leukemia in A Young Female Adult Presenting for Care in A Resource Constrained Setting","authors":"Simakando A. Mwizabi, Brian Musuka, Celine Mwape, Audrey Mulenga, Mutale Mweene, Catherine Maliko, G. Maksoud, Mwinsa Chimese, Mabvuto Zulu, Sebastian Chinkoyo, Christopher Nyirenda","doi":"10.18535/cmhrj.v3i6.285","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i6.285","url":null,"abstract":"Background: Acute leukemia is a rare malignant disorder arising from an abnormal proliferation of hematopoietic precursor cells. With advances in the management of leukemia, patients of acute leukemia have high chances of achieving adequate remission and survival. However, due to late presentation, diagnosis and treatment, the disease has significantly contributed to high morbidity and mortality especially in resource limited settings.\u0000Method: A comprehensive history and physical examination was taken, coupled with literature review. Various rationale for each intervention and recommended interventions unavailable in our setting were noted.\u0000Results: Early diagnosis and treatment of leukemia and its complications is a major public health concern for which the general public needs to be educated on. In this case report, material and human resource constraints in our setting may contribute towards the patient’s poor clinical outcome.\u0000Conclusion and recommendations: Acute leukemia is a manageable disorder provided the availability of appropriate resources and interventions being implemented early. There is therefore need to equip our health facilities and personnel with resources towards early clinical detection, diagnosis and treatment which measures are essential for successful management and prevention of unwanted complications.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using Gene Expression Profiling, İdentify Genetic Changes İn Multiple Sclerosis (MS) And Determine Molecular Pathways 利用基因表达谱分析确定多发性硬化症（MS）的基因变化并确定分子通路

Clinical Medicine And Health Research Journal Pub Date : 2023-12-02 DOI: 10.18535/cmhrj.v3i6.286

Z. Kucukakcali, İpek BALIKÇI ÇİÇEK

{"title":"Using Gene Expression Profiling, İdentify Genetic Changes İn Multiple Sclerosis (MS) And Determine Molecular Pathways","authors":"Z. Kucukakcali, İpek BALIKÇI ÇİÇEK","doi":"10.18535/cmhrj.v3i6.286","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i6.286","url":null,"abstract":"Aim: In this study, an open-access dataset of RNAseq data from proggressive multiple sclerosis (MS) samples and matched normal-appearing white matter (NAWM) samples was used to identify genetic alterations that play a role in the development of MS, the prevalence is on the rise in both industrialized and emerging nations.\u0000Material and methods: The dataset utilized in this investigation comprises nine samples of lesions and corresponding samples of NAWM tissue. The gene expression analysis was conducted on the dataset using the limma package in the R programming language. The clusterProfiler software was utilized to do enrichment analysis.\u0000Results: 493 genes showed different up- or down-regulation in lesion tissues compared to NAWM tissues. According to the results of the enrichment analysis with these genes, the processes that play a role in progressive MS cancer are intracelluler anatomical structure, membrane bounded organelle, non-membrane bounded organelle, intracelluler non-membrane bounded organelle.\u0000Conclusion: As a result, it can be said that the genetic structure of progressive MS tissues (lesion) changes compared to NAWM tissues, with the information obtained from gene expression analysis and enrichment analysis. It might be argued that the therapeutic efficacy of the disease can be enhanced by the comprehensive and diverse analysis of biomarkers.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"119 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138607234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete Left Bundle Branch Block in Acute Coronary Syndrome with ST Segment Elevation: Epidemiological Features ST段抬高急性冠脉综合征完全性左束支阻滞:流行病学特征

Clinical Medicine And Health Research Journal Pub Date : 2023-11-14 DOI: 10.18535/cmhrj.v3i6.272

Hanane ZOUZOU

{"title":"Complete Left Bundle Branch Block in Acute Coronary Syndrome with ST Segment Elevation: Epidemiological Features","authors":"Hanane ZOUZOU","doi":"10.18535/cmhrj.v3i6.272","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i6.272","url":null,"abstract":"Background: Complete left bundle branch in acute coronary syndrome with ST segment elevation is not common, but known as a sign of poor prognosis. Several international studies had reported its incidence and related mortality, but its epidemiological data is lacking in Algeria. Aims: The main objective of our study is the determination of the frequency of complete left bundle branch block in acute coronary syndrome with ST segment elevation, the secondary objective was the analysis of its predictive factors and related mortality. Methods and materials: In this prospective study, conducted in the cardiology department of Hussein Dey hospital (Algiers-Algeria), 467 patients with acute coronary syndrome with elevated ST segment (87 women and 380 men) were enrolled between 28 February 2014 and 16 July 2015. The average age is 60 ± 13 years; at admission, a Holter recorder was attached for continuous ECG monitoring during 48 hours. Kruskal’s ANNOVA or H tests were used for comparison of quantitative variables, χ2 test or Fisher’s exact test, were used for qualitative variables, all tests were performed with 1st species risk of 5%. Results: The frequency of complete left bundle brunch block is 1.7 % (8 patients), CI 95%: [0.5%-2.9%], multivariate analysis identified the two independent predictors: diabetes type 1, and Angiotensin Receptor-Blockers as current treatment. Despite the risk of mortality expressed by Hazard Ration (HR) is 4.7, but remains not significant: CI95%: [0.62-36], p = 0.134; however, the risk of ventricular fibrillation occurrence is high, with relative risk (RR) at 7.17, CI 95 %: [2.70-19.03], p = 0.007. Conclusion: Complete left bundle brunch block is not common in acute coronary syndrome with elevated ST segment, its predictive factors according to our study are: Diabetes type 1 and Angiotensin Receptor-Blockers as current treatment. The high-risk mortality in the left bundle brunch block group isn’t significant; however the risk of ventricular fibrillation occurrence is high.","PeriodicalId":500154,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"53 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134901460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0