Acute Leukemia in A Young Female Adult Presenting for Care in A Resource Constrained Setting

Simakando A. Mwizabi, Brian Musuka, Celine Mwape, Audrey Mulenga, Mutale Mweene, Catherine Maliko, G. Maksoud, Mwinsa Chimese, Mabvuto Zulu, Sebastian Chinkoyo, Christopher Nyirenda
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Abstract

Background: Acute leukemia is a rare malignant disorder arising from an abnormal proliferation of hematopoietic precursor cells. With advances in the management of leukemia, patients of acute leukemia have high chances of achieving adequate remission and survival. However, due to late presentation, diagnosis and treatment, the disease has significantly contributed to high morbidity and mortality especially in resource limited settings. Method: A comprehensive history and physical examination was taken, coupled with literature review. Various rationale for each intervention and recommended interventions unavailable in our setting were noted. Results: Early diagnosis and treatment of leukemia and its complications is a major public health concern for which the general public needs to be educated on. In this case report, material and human resource constraints in our setting may contribute towards the patient’s poor clinical outcome. Conclusion and recommendations: Acute leukemia is a manageable disorder provided the availability of appropriate resources and interventions being implemented early. There is therefore need to equip our health facilities and personnel with resources towards early clinical detection, diagnosis and treatment which measures are essential for successful management and prevention of unwanted complications.
在资源有限的环境中接受治疗的年轻女性成人的急性白血病
背景:急性白血病是一种罕见的由造血前体细胞异常增殖引起的恶性疾病。随着白血病治疗的进展,急性白血病患者有很高的机会获得足够的缓解和生存。然而,由于出现、诊断和治疗较晚,这种疾病在很大程度上造成了高发病率和死亡率,特别是在资源有限的环境中。方法:对患者进行全面病史和体格检查,并结合文献复习。指出了每种干预措施的各种基本原理和在我们的环境中不可用的推荐干预措施。结果:白血病及其并发症的早期诊断和治疗是一个重大的公共卫生问题,需要对公众进行教育。在这个病例报告中,在我们的环境中,物质和人力资源的限制可能导致患者临床结果不佳。结论和建议:急性白血病是一种可控制的疾病,只要提供适当的资源和早期实施干预措施。因此,需要为我们的卫生设施和人员提供资源,以便进行早期临床检测、诊断和治疗,这些措施对于成功管理和预防不必要的并发症至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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