Athanasia Vlahou, Fotini Ampatzidou, George Koulaouzidis, Odysseas Drosos, Nikolaos Antonopoulos, George Drosos
{"title":"The role of mediastinal blood in the development of postoperative atrial fibrillation after cardiac surgery.","authors":"Athanasia Vlahou, Fotini Ampatzidou, George Koulaouzidis, Odysseas Drosos, Nikolaos Antonopoulos, George Drosos","doi":"10.5114/kitp.2025.158038","DOIUrl":"10.5114/kitp.2025.158038","url":null,"abstract":"<p><strong>Introduction: </strong>Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery. Although many risk factors have been studied, none has emerged as a dominant and widely applicable prophylactic measure.</p><p><strong>Aim: </strong>The aim of our study was to investigate the relationship between the amount of shed mediastinal blood and the occurrence of postoperative AF.</p><p><strong>Material and methods: </strong>From February 2021 to March 2024, 1140 patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) were evaluated for the occurrence of postoperative AF (POAF). The following parameters were recorded and analyzed: age, gender, diabetes mellitus, hypertension, smoking, dyslipidemia, chronic obstructive pulmonary disease (COPD), history of stroke, pre-operative ejection fraction, CPB, aortic cross clamp time, and amount of mediastinal drainage. All variables were analyzed using logistic regression to assess their association with new-onset AF.</p><p><strong>Results: </strong>A total of 388 (33.59%) patients developed paroxysmal AF. According to our study, after multiple regression analysis, new onset atrial fibrillation showed statistically significant relationships with age (<i>p</i> = 0.001), hypertension (<i>p</i> = 0.001), duration of CPB (<i>p</i> = 0.04), and the amount of mediastinal drainage (<i>p</i> = 0.04).</p><p><strong>Conclusions: </strong>The occurrence of postoperative AF is strongly associated with the amount of shed mediastinal blood.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"267-270"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Piotr Gabryel, Dominika Zielińska, Lidia Szlanga, Alicja Werblińska, Jakub Woźniak, Maciej Bryl, Cezary Piwkowski
{"title":"Prehabilitation as a key component of the Enhanced Recovery After Surgery (ERAS) program in patients with lung cancer: a narrative review.","authors":"Piotr Gabryel, Dominika Zielińska, Lidia Szlanga, Alicja Werblińska, Jakub Woźniak, Maciej Bryl, Cezary Piwkowski","doi":"10.5114/kitp.2025.154844","DOIUrl":"10.5114/kitp.2025.154844","url":null,"abstract":"<p><p>Lung cancer remains a major health challenge despite recent advances in diagnostics and treatment. Surgical resection, particularly in early stages, offers the best chance for cure. Enhanced Recovery After Surgery (ERAS) programs have been shown to improve outcomes in various surgical areas. This narrative review summarizes current evidence on the role of prehabilitation within ERAS for lung cancer surgery and presents the organizational model from a high-volume academic thoracic surgery center. Key elements of prehabilitation include smoking cessation, nutritional optimization, physical activity enhancement, and patient education, all delivered by a multidisciplinary team. Despite organizational challenges, preoperative ERAS programs demonstrate benefits for patients and hospitals, supporting their broader implementation in thoracic surgery.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"206-211"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vasileios Leivaditis, Elias Liolis, Nikolaos Baltayiannis, Pavlos Sarof, Alexandra Pagoulatou, Konstantinos Grapatsas, Andreas Antzoulas, Dimitrios Litsas, Panagiotis Dimitrios Papadopoulos, George Theofanis, Konstantinos Nikolakopoulos, Paraskevi Katsakiori, Athanasios Papatriantafyllou, Efstratios Koletsis, Marina Michalaki, Francesk Mulita
{"title":"Diving retrosternal goiter and the dilemma of sternotomy: indications, predictors and surgical considerations.","authors":"Vasileios Leivaditis, Elias Liolis, Nikolaos Baltayiannis, Pavlos Sarof, Alexandra Pagoulatou, Konstantinos Grapatsas, Andreas Antzoulas, Dimitrios Litsas, Panagiotis Dimitrios Papadopoulos, George Theofanis, Konstantinos Nikolakopoulos, Paraskevi Katsakiori, Athanasios Papatriantafyllou, Efstratios Koletsis, Marina Michalaki, Francesk Mulita","doi":"10.5114/kitp.2025.154929","DOIUrl":"10.5114/kitp.2025.154929","url":null,"abstract":"<p><p>A goiter is defined as an enlargement of the thyroid gland, typically resulting in a doubling in size or a weight exceeding 40 g. It affects approximately 5% of the global population. Diving, or substernal, goiters occur when more than 50% of the thyroid extends into the mediastinum, with an incidence ranging from 5% to 15.7% across various studies. An alternative definition describes diving goiters as those extending more than 3 cm below the sternal notch on chest computed tomography with the neck in hyperextension, or beyond the fourth thoracic vertebra. In this review, we outline the key clinical and radiological criteria that indicate when sternotomy is required for the surgical management of diving goiters.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"174-181"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hari Govind Varma, Digvijay Gowda, Susovan Halder, Pritish K Nayak, Lalit Kapoor
{"title":"Redo aortic valve replacement with the Perceval valve: the ideal stepping stone in the lifetime management of aortic stenosis?","authors":"Hari Govind Varma, Digvijay Gowda, Susovan Halder, Pritish K Nayak, Lalit Kapoor","doi":"10.5114/kitp.2025.154842","DOIUrl":"10.5114/kitp.2025.154842","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"212-215"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shukur Musayev, Volkan Karacam, Pınar A Yılmaz, Kemal C Tertemiz, Meltem Sevinç, Bekir U Ergur, Aydın Sanlı, Nezih Ozdemir
{"title":"Effect of glutamine and arginine treatment on the inflammatory response in a rat model of pulmonary contusion.","authors":"Shukur Musayev, Volkan Karacam, Pınar A Yılmaz, Kemal C Tertemiz, Meltem Sevinç, Bekir U Ergur, Aydın Sanlı, Nezih Ozdemir","doi":"10.5114/kitp.2025.154888","DOIUrl":"10.5114/kitp.2025.154888","url":null,"abstract":"<p><strong>Introduction: </strong>Pulmonary contusion leads to alveolar damage and inflammation, which can progress to acute lung injury and acute respiratory distress syndrome. Glutamine and L-arginine play critical roles in immune regulation and inflammation control, showing potential protective effects in lung injury models.</p><p><strong>Aim: </strong>This study aimed to investigate the effects of glutamine and/or arginine, which play significant roles in the immuno-inflammatory response, on mitigating inflammation in an experimentally induced pulmonary contusion model.</p><p><strong>Material and methods: </strong>Thirty male Wistar Albino rats from the same colony were randomly divided into five groups (<i>n</i> = 6 per group). Group I (sham) received no trauma or treatment. Bilateral pulmonary contusion was induced in Groups II-V. Group II received 0.9% saline; Group III received 200 mg/kg/day intraperitoneal glutamine; Group IV received 200 mg/kg/day intraperitoneal arginine; and Group V received both glutamine (200 mg/kg/day) and arginine (150 mg/kg/day). All treatments were administered for 3 consecutive days. Rats were sacrificed three days after the procedure, and histopathologic evaluation was performed afterwards. Three different parameters were scored: inflammation intensity, intraalveolar hemorrhage, and alveolar congestion. Statistical analysis was performed using the Mann-Whitney <i>U</i> test.</p><p><strong>Results: </strong>Compared to the untreated trauma group, all treatment groups showed significant histopathological improvement (<i>p</i> < 0.05). The arginine-only group demonstrated greater effectiveness across all parameters compared to the combined treatment group (<i>p</i> < 0.05). No significant difference was observed between the glutamine-only and arginine-only groups (<i>p</i> > 0.05).</p><p><strong>Conclusions: </strong>Both glutamine and arginine treatments were effective in reducing inflammation following pulmonary contusion. However, combined treatment was less effective than arginine alone.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"158-162"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariusz Kowalewski, Michał Farkowski, Jakub Batko, Natalia Ogorzelec, Michał Zembala, Oskar Kowalski, Sebastian S Aboul-Hassan, Rafał Płaksej, Piotr Buchta, Grzegorz Hirnle, Marek Jastrzębski, Agnieszka Wojdyła-Hordyńska, Krzysztof Bartus, Marek A Deja, Marek Jasiński, Tomasz Hrapkowicz, Bohdan Maruszewski, Janusz Skalski, Kazimierz Widenka, Piotr Kułakowski, Agnieszka Tycińska, Robert J Gil, Sebastian Stec, Adam Sokal, Piotr Suwalski
{"title":"Position paper of the Polish Society of Cardiothoracic Surgeons and the Heart Rhythm Association of the Polish Society of Cardiology on atrial fibrillation hybrid management.","authors":"Mariusz Kowalewski, Michał Farkowski, Jakub Batko, Natalia Ogorzelec, Michał Zembala, Oskar Kowalski, Sebastian S Aboul-Hassan, Rafał Płaksej, Piotr Buchta, Grzegorz Hirnle, Marek Jastrzębski, Agnieszka Wojdyła-Hordyńska, Krzysztof Bartus, Marek A Deja, Marek Jasiński, Tomasz Hrapkowicz, Bohdan Maruszewski, Janusz Skalski, Kazimierz Widenka, Piotr Kułakowski, Agnieszka Tycińska, Robert J Gil, Sebastian Stec, Adam Sokal, Piotr Suwalski","doi":"10.5114/kitp.2025.155459","DOIUrl":"10.5114/kitp.2025.155459","url":null,"abstract":"<p><p>This position paper, jointly authored by the Polish Society of Cardiothoracic Surgeons and the Heart Rhythm Association of the Polish Society of Cardiology, defines the role of hybrid approaches in the treatment of cardiac arrhythmias, particularly atrial fibrillation. We present a rationale for integrating epicardial and endocardial ablation strategies, summarize current evidence, and advocate for multidisciplinary planning, including arrhythmia treatment during cardiac surgery for other indications and atrial fibrillation treatment as a stand-alone procedure. The paper highlights the importance of minimally invasive approaches, the need for heart team-based planning, structured curricula, and postoperative referral pathways for comprehensive management of atrial fibrillation and non-atrial fibrillation arrhythmias.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"143-157"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence nanoparticle-based drug delivery systems and targeted delivery of therapeutics for the treatment of cardiovascular diseases: a systematic review.","authors":"Fatemeh Kamali, Seyedehmahrokh Moosavimordghafari, Mohammad Ghasemian, Narges Kamali, Seyedeh Mahta Mojab, Fatemeh Nikfard, Zahra Nikfard, Saber Bakhtiaryfar","doi":"10.5114/kitp.2025.154852","DOIUrl":"10.5114/kitp.2025.154852","url":null,"abstract":"<p><p>This article reviews the progress of nanoparticles as drug carriers in the treatment of cardiovascular diseases, and how nanoparticles can deliver anti-inflammatory, anti-proliferative, and anticoagulant drugs directly to the surgical site in surgical procedures. For this, 45 articles published between 2005 and 2024 with keywords including \"Artificial intelligence Nanoparticle\", \"Emergency Medicine Unit\", and \"Therapeutic for the treatment of cardiovascular diseases\" in Scopus, Elsevier, Web of Science and ScienceDirect were reviewed. Nanoparticle-based drug delivery systems have demonstrated several noteworthy therapeutic benefits in the treatment of cardiovascular disorders since they were first used in the cancer field to deliver safer and more effective chemotherapeutics. By delivering targeted and site-specific medications with controlled release, nanoparticle-based drug delivery systems modify the biodistribution of therapeutic agents. An optimal material for cardiovascular therapeutics would be a nanoparticle based on metal, lipid, or polymer.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 3","pages":"182-189"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}