Kardiochirurgia I Torakochirurgia Polska最新文献

{"title":"Endothelin-1 and endothelial nitric oxide (eNOs) synthase as predictive biomarkers of clinical-subclinical atherosclerosis related to diabetes mellitus: a cross-sectional study.","authors":"Zeena Hussien Khudair, Abeer Cheaid Yousif Al-Fatlawi, Ahmed Qasim Alhaideri","doi":"10.5114/kitp.2025.158073","DOIUrl":"10.5114/kitp.2025.158073","url":null,"abstract":"<p><strong>Introduction: </strong>Atherosclerosis is a chronic inflammatory disease characterized by arterial hardening and narrowing due to fibrous plaque formation.</p><p><strong>Aim: </strong>This study aimed to evaluate the relationship between endothelin-1, endothelial nitric oxide synthase (eNOS), and clinical versus subclinical coronary atherosclerosis in male patients, as well as their association with type 2 diabetes mellitus.</p><p><strong>Material and methods: </strong>This cross-sectional study included 90 male patients aged 20-60 years (mean age: 33.00 ±6.13), divided equally into clinical (<i>n</i> = 45, mean age: 34.50 ±4.95) and subclinical (<i>n</i> = 45, mean age: 32.25 ±7.23) coronary atherosclerosis groups. Serum endothelin-1 and endothelial nitric oxide (eNOS) were measured using ELISA kits. Insulin resistance was estimated by HOMA-IR: (fasting insulin × fasting glucose)/405. Lipid profiles, glucose parameters, and other biochemical markers were assessed.</p><p><strong>Results: </strong>Clinical atherosclerosis patients had significantly higher endothelin-1 (19.646 ±5.045 pg/ml), insulin (4.175 ±1.667 μIU/ml), HOMA-IR (2.137 ±1.059), HbA1c (8.893 ±2.462 mmol/mol), C-peptide (123.614 ±32.939 pg/ml), and lipid parameters compared to the subclinical group (endothelin-1: 7.555 ±0.881 pg/ml; insulin: 2.582 ±0.238 μIU/ml; HOMA-IR: 0.760 ±0.091; HbA1c: 7.240 ±2.747 mmol/mol; C-peptide: 40.291 ±9.174 pg/ml). eNOS was higher in subclinical (825.528 ±321.027 pg/ml) versus clinical (299.499 ±57.810 pg/ml) patients. ROC analysis showed that endothelin-1 had the highest diagnostic accuracy (AUC 98.025%, sensitivity 95.533%, specificity 95.556%, cutoff 10.189 pg/ml). eNOS and HOMA-IR also showed strong predictive power (AUC 95.358% and 97.037%, respectively).</p><p><strong>Conclusions: </strong>An imbalance of elevated endothelin-1 and reduced eNOS contributes to endothelial dysfunction and atherosclerosis progression. These biomarkers may serve as strong predictive indicators for clinical and subclinical disease.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"285-293"},"PeriodicalIF":1.3,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid MELODY valve implantation in primary anatomical correction of unfavorable complete atrioventricular canal in an infant with genetic disorders and frailty syndrome.","authors":"Konrad Paczkowski, Julia Haponiuk-Skwarlińska, Maciej Chojnicki, Katarzyna Leszczyńska, Katarzyna Gierat-Haponiuk, Ireneusz Haponiuk","doi":"10.5114/kitp.2025.158077","DOIUrl":"10.5114/kitp.2025.158077","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"294-296"},"PeriodicalIF":1.3,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute heart failure in infective endocarditis treated with valve-in-valve transcatheter aortic valve implantation.","authors":"Katarzyna Wijatkowska-Batko, Jakub Rąpała, Marian Burysz, Agata Krawczyk-Ożóg, Jakub Batko","doi":"10.5114/kitp.2025.158085","DOIUrl":"10.5114/kitp.2025.158085","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"302-304"},"PeriodicalIF":1.3,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maintaining functionality by graft interposition in a Brescia-Cimino arteriovenous fistula resembling an ulnar-basilic fistula.","authors":"Spyros Papadoulas, Vasileios Leivaditis, Andreas Tsimpoukis, Melina Stathopoulou, Konstantinos Nikolakopoulos, Chrysanthi Papageorgopoulou, Konstantinos Tasios, Elias Liolis, Andreas Antzoulas, Dimitrios Litsas, Panagiotis Dimitrios Papadopoulos, George Theofanis, Paraskevi Katsakiori, Marios Papasotiriou, Panagiotis Kitrou, Francesk Mulita","doi":"10.5114/kitp.2025.158043","DOIUrl":"10.5114/kitp.2025.158043","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"299-301"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) failure: analysis of comorbidities and complications - a 10-year experience.","authors":"Artur Barshatskyi, Olga Klementova, Jana Zapletalova, Ondrej Zuscik, Petr Santavy, Zdenek Vyhnak, Jakub Konecny, Marek Vicha, Martin Simek","doi":"10.5114/kitp.2025.158037","DOIUrl":"10.5114/kitp.2025.158037","url":null,"abstract":"<p><strong>Introduction: </strong>Extracorporeal membrane oxygenation (ECMO) is a rescue method in the treatment of severe cardiac and/or respiratory failure in patients with different etiological factors of this failure and also of different ages. The question of ECMO support of patients has arisen more frequently recently, as a result of the expansion of the indication criteria for this support and the increase in the contingent of patients with severe cardiac and/or respiratory failure.</p><p><strong>Material and methods: </strong>A retrospective study was performed in patients with veno-arterial ECMO (VA-ECMO) support for cardiac or cardiorespiratory failure over a 10-year period at a single ECMO center. In this study, comorbidities and peri- and post-procedural complications were analyzed in search of predictors of failure of the method. Furthermore, the composition of treated patients was analyzed according to the indication for support and known comorbidities at the time the support was indicated.</p><p><strong>Results: </strong>The largest indication group among patients supported by VA-ECMO was those with acute coronary syndrome (<i>n</i> = 42), accounting for nearly 37% of the cohort. Only 22 patients in the entire cohort had no comorbidities, accounting for 19%. Complications occurred in 77 patients, accounting for nearly 68% of patients supported.</p><p><strong>Conclusions: </strong>Analysis of the results shows a correlation of survival with the incidence of infection at the cannulation site and limb ischemia. Survival at 30 days correlated with multiorgan dysfunction syndrome, cerebral edema and cannulation site infection. Survival at 90 days correlated with cannulation site infection. Survival at 12 months correlated with limb ischemia and cannulation site infection. Of the comorbidities known at the time of indication, only atrial fibrillation was correlated with 12-month survival and hospitalization mortality (significance level <i>p</i> = 0.049).</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"271-276"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive approach for ascending aorta aneurysm replacement - next steps in minimally invasive cardiac surgery: a case series.","authors":"Mateusz Janeczek, Wojtek Karolak, Nikodem Ulatowski, Abigail Kimber","doi":"10.5114/kitp.2025.158039","DOIUrl":"10.5114/kitp.2025.158039","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"305-307"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Completely unroofed coronary sinus without persistent left superior vena cava: a rare entity.","authors":"Marek Kardos, Fadi Sabateen, Pavel Valentik, Lucia Bobik, Matej Nosal","doi":"10.5114/kitp.2025.158027","DOIUrl":"10.5114/kitp.2025.158027","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"310-311"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lobectomy offers higher incidence of up-staging in patients with T1a-c non-small cell lung carcinomas: Is completion lobectomy necessary?","authors":"Gizem Özçıbık Işık, Burcu Kılıç, Ezel Erşen, Mehmet K Kaynak, Hasan V Kara, Akif Turna","doi":"10.5114/kitp.2025.158036","DOIUrl":"10.5114/kitp.2025.158036","url":null,"abstract":"<p><strong>Introduction: </strong>Completion lobectomy is defined as the excision of the remaining lobe following a previous sublobar resection. While it is considered a salvage option in selected cases, its impact on nodal staging and overall survival remains unclear in patients with early-stage non-small cell lung cancer (NSCLC).</p><p><strong>Aim: </strong>This study aimed to evaluate the effect of completion lobectomy on nodal upstaging and overall survival in patients with T1a-c NSCLC.</p><p><strong>Material and methods: </strong>A retrospective analysis was conducted on 477 patients with pathologically confirmed NSCLC and tumor size ≤ 3 cm, who underwent sublobar resection (<i>n</i> = 45), lobectomy (<i>n</i> = 270), or completion lobectomy (<i>n</i> = 117) between 2001 and 2023. Patients were stratified into subgroups based on tumor size: 0-2 cm (T1a,b) and 2-3 cm (T1c). Clinical, surgical, and pathological parameters, as well as survival data, were compared among groups.</p><p><strong>Results: </strong>The lobectomy group demonstrated significantly higher rates of N1 nodal involvement compared to the sublobar group (<i>p</i> < 0.001). The VATS approach and N0 status were more common in the sublobar resection group (<i>p</i> < 0.001). Perineural, lymphatic, and vascular invasion were significantly less frequent in the sublobar group (<i>p</i> = 0.001, <i>p</i> = 0.032, and <i>p</i> = 0.004, respectively). No significant difference in overall survival was observed among surgical groups (<i>p</i> = 0.164); however, lobectomy yielded better survival in T1a,b tumors (<i>p</i> = 0.037). Nodal status, perineural invasion, and stage were independent predictors of survival (p = 0.002 and <i>p</i> = 0.02).</p><p><strong>Conclusions: </strong>Lobectomy results in higher pathological upstaging in cT1N0M0 NSCLC. Completion lobectomy is feasible and safe when nodal upstaging occurs following segmentectomy, though it may not confer a survival advantage in cT1aN0 cases.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"241-248"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contralateral thoracic duct injury after unilateral cervical stab wound: a rare cause of chylothorax.","authors":"Çağatay Çetinkaya","doi":"10.5114/kitp.2025.158029","DOIUrl":"10.5114/kitp.2025.158029","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"316-318"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted bronchial artery embolization: a life-saving intervention for recurrent massive hemoptysis in bronchiectasis.","authors":"Vasileios Leivaditis, Spyros Papadoulas, Konstantinos Nikolakopoulos, Nikolaos G Baikoussis, Konstantinos Grapatsas, Konstantinos Tasios, Elias Liolis, Andreas Antzoulas, Dimitrios Litsas, Panagiotis Dimitrios Papadopoulos, George Theofanis, Paraskevi Katsakiori, Chrysa Andrikopoulou, Manfred Dahm, Efstratios Koletsis, Francesk Mulita","doi":"10.5114/kitp.2025.158040","DOIUrl":"10.5114/kitp.2025.158040","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"22 4","pages":"312-315"},"PeriodicalIF":1.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}