Nervenarzt最新文献_第2页

[Electroconvulsive therapy for decades-long treatment-resistant schizoaffective disorder: remission and restoration of decision-making capacity]. [电痉挛疗法治疗长达数十年的难治性分裂情感障碍：决策能力的缓解和恢复]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-07 DOI: 10.1007/s00115-026-02013-x

Guillermo Calvi, Dirk Haufe, Pavlo Lopatnov, Peter Prager, Johannes Petzold, Maik Spreer

引用次数: 0

Rodent models of aggression: from mechanisms to clinical translation. 啮齿动物的攻击模式：从机制到临床翻译。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-07 DOI: 10.1007/s00115-026-02011-z

Jonathan Reinwald, Marc Spehr, Aet O'Leary, David Slattery, Wolfgang Weber-Fahr, Wolfgang Kelsch

{"title":"Rodent models of aggression: from mechanisms to clinical translation.","authors":"Jonathan Reinwald, Marc Spehr, Aet O'Leary, David Slattery, Wolfgang Weber-Fahr, Wolfgang Kelsch","doi":"10.1007/s00115-026-02011-z","DOIUrl":"https://doi.org/10.1007/s00115-026-02011-z","url":null,"abstract":"Aggression is an evolutionarily conserved social behavior that becomes clinically relevant when it loses contextual and inhibitory regulation. Rodent models do not serve to reproduce the full complexity of human violence, with its legal, moral, cultural, and interpersonal dimensions. Their translational value lies instead in making core mechanisms of aggression regulation experimentally accessible. This article discusses how rodent models help to distinguish adaptive from dysregulated aggression; to select clinically informative paradigms; and to identify causal pathways that shape attack threshold, escalation, persistence, reward value, and inhibitory control. Rodent studies have mapped a multilevel control architecture in which social sensory threat is appraised through amygdala-hypothalamic pathways, hypothalamic and midbrain circuits organize attack-related behavior, and corticostriatal systems contribute to motivation and regulatory control. Rather than acting as fixed modules, these circuits are shaped by experience, internal state, sex and endocrine modulation, immune signaling, and aggression-related reward. Next-generation models should therefore complement traditional reductionist assays with longitudinal trajectories, socially embedded phenotyping, dysregulation readouts, and measures of distributed network and body-brain states. Within TRR 379, rodent models enable mechanism-focused translation by helping to identify biosignatures and modifiable pathways for future interventions in dysregulated aggression.","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Selected psychiatric aspects of disorders of intellectual development]. [智力发展障碍的精神病学方面的选择]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2026-09-07 DOI: 10.1007/s00115-026-01986-z

Michael Seidel, Thomas Pollmächer

引用次数: 0

Epidemiology of aggression and violence in mental disorders and the approach of TRR 379. 精神障碍患者攻击与暴力的流行病学及trr379检测方法。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 DOI: 10.1007/s00115-026-02005-x

Ute Habel, Sabine Herpertz, Andreas Reif

{"title":"Epidemiology of aggression and violence in mental disorders and the approach of TRR 379.","authors":"Ute Habel, Sabine Herpertz, Andreas Reif","doi":"10.1007/s00115-026-02005-x","DOIUrl":"https://doi.org/10.1007/s00115-026-02005-x","url":null,"abstract":"Aggression in mental disorders (AMD) poses a challenge for everyday clinical practice and has far-reaching societal implications. The biological foundations of the different manifestations, developmental trajectories, and transdiagnostic and disorder-specific deficits remain largely unknown. One reason for the apparent lack of understanding of the complex mechanisms underlying AMD is the heterogeneity of both aggression and mental disorders themselves. This, in turn, hinders progress in developing effective prevention and intervention strategies. Therefore, a collaborative approach between clinical and experimental neuroscientists is required to address this issue comprehensively and in a multimodal manner. The proposed initiative aims to advance knowledge on the biological bases of AMD and its developmental course. The Transregional Collaborative Research Center 379 (TRR) will follow the Research Domain Criteria (RDoC) framework, investigating multiple aspects that characterize aggression: genetic and molecular mechanisms as well as hormonal, neural, and associated behavioral systems. Thus, the TRR aims to identify biosignatures of AMD based on multidimensional pathways that underlie the different manifestations of aggression to enable the development of tailor-made biosignature-specific prevention and intervention.","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The importance of psychiatry in the care and research of Post-COVID]. [精神病学在covid - 19后护理和研究中的重要性]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2026-03-17 DOI: 10.1007/s00115-026-01951-w

Martin Walter, Kristina Adorjan, Malek Bajbouj, Jürgen Deckert, Sabine Köhler, Klaus Lieb, Josef Priller, Claudia Schillig, Anna-Karina Schomburg, Georg Schomerus, Meryam Schouler-Ocak, Andreas Meyer-Lindenberg

引用次数: 0

[Associations between involuntary commitment measures and the ambient temperature in inpatient psychiatric standard care : A retrospective data analysis]. [非自愿承诺措施与住院精神病患者标准护理环境温度之间的关系：回顾性数据分析]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2025-09-24 DOI: 10.1007/s00115-025-01902-x

Daniel Kamp, Timo Jendrik Faustmann, Juha Marko Lahnakoski, Claus Lamm, Boryana Todorova, Michaela Jänner, Leonhard Schilbach

引用次数: 0

[When brain abscesses run in the family…]. [当脑脓肿在家族中遗传时…]

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2026-07-02 DOI: 10.1007/s00115-026-01997-w

Christoph Preul, Kai Kallenberg, Tobias Neumann-Haefelin

引用次数: 0

[Neurocognitive profile and vulnerability for mental health problems in selected genetic syndromes with disorders of intellectual development]. [某些智力发育障碍遗传综合征的神经认知特征和心理健康问题的易感性]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2026-04-14 DOI: 10.1007/s00115-026-01962-7

Klaus Sarimski

引用次数: 0

[(Es)ketamine: practice update]. [氯胺酮：实践更新]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2026-08-17 DOI: 10.1007/s00115-026-02001-1

Stefan Vestring, Katharina Domschke, Claus Normann

引用次数: 0

[Female psychiatrists in films: origin and evolution of a gender-specific character stereotype (1935-2020)]. [电影中的女性精神科医生：特定性别角色刻板印象的起源和演变（1935-2020）]。

IF 1.1 4区医学

Nervenarzt Pub Date : 2026-09-01 Epub Date: 2025-09-25 DOI: 10.1007/s00115-025-01901-y

Dennis Henkel, Walter Stehling, Katja Wagemans

{"title":"[Female psychiatrists in films: origin and evolution of a gender-specific character stereotype (1935-2020)].","authors":"Dennis Henkel, Walter Stehling, Katja Wagemans","doi":"10.1007/s00115-025-01901-y","DOIUrl":"10.1007/s00115-025-01901-y","url":null,"abstract":"Background: In the medical world women have taken on a steadily increasing role over the last decades and are now numerically superior to men in many specialized fields. In this context psychiatry is no exception. As cinematics always reflect social developments, this fact raises the question of whether the representation of female psychiatrists in films and series takes this trend into account.Methods: Film productions presenting female psychiatrist characters were systematically identified by means of a targeted search in relevant databases and a supplementary literature search. In addition, pertinent film examples up to the twenty-first century were analyzed.Objective: The focus is on research questions relevant to social, medical and film history: Does the image of screen psychiatrists correspond to reality? Are stereotypes served or initiated? How does the portrayal differ from the male counterpart?Results and conclusion: The exemplary examination of 18 films and 1 series reveals the early emergence of a gender-specific character cliché which is still influential today: the female psychiatrist as an empathic, sensitive and emotionally active doctor who can make a successful career by virtue of these character traits but who is also emotionally and socially marginalized as a result. A chronologically structured analysis not only reveals social contexts of this stereotype but also shows mechanisms of media transmission. Reflecting on this distorted image in professional settings can help to recognize and specifically address media-induced reservations in patients.","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":"461-467"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13550060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0