Nervenarzt最新文献

{"title":"[Autism spectrum disorders-Transition from adolescence into adulthood].","authors":"Christine M Freitag, Ludger Tebartz van Elst","doi":"10.1007/s00115-026-01960-9","DOIUrl":"10.1007/s00115-026-01960-9","url":null,"abstract":"<p><p>Autism spectrum disorders (ASD) are neurodevelopmental disorders with a prevalence of approximately 0.7%. People with ASD show characteristic social interaction, verbal and nonverbal communication, routine-like and inflexible behavior, special interests and altered perception. ASD manifest in the first decade of life and usually persist throughout life. Like most other neurodevelopmental disorders, they are therefore inevitably not only a topic of child and adolescent psychiatry, psychosomatics and psychotherapy (CAPPP) but also of adult psychiatry, psychosomatics and psychotherapy (APPP); however, the transition from adolescence into adulthood poses a particular challenge for affected individuals, their caregivers, as well as for professionals in the healthcare and social welfare systems. Key aspects of the transition period include the treatment of comorbid mental, cognitive and language disorders as well as social legislation and healthcare aspects. This article depicts these aspects from the perspective of CAPPP and APPP.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":"246-251"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13171725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Successful treatment of a male patient with unipolar depressive 48-h ultra-rapid cycling with lithium].","authors":"Georg Juckel, Kai Wetzel, Paraskevi Mavrogiorgou","doi":"10.1007/s00115-026-01952-9","DOIUrl":"10.1007/s00115-026-01952-9","url":null,"abstract":"","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":"297-300"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13171689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ego documents of people with epilepsy during National Socialism].","authors":"T Baumann, A Karenberg, H Fangerau","doi":"10.1007/s00115-025-01865-z","DOIUrl":"10.1007/s00115-025-01865-z","url":null,"abstract":"<p><strong>Background: </strong>People with epilepsy were a stigmatized and persecuted group under National Socialism. Nevertheless, there are only a few historical works that specifically address the reality of life for this group in Nazi Germany.</p><p><strong>Objective: </strong>In the sense of a heuristic pioneer study, the reality of life of in-patients with epilepsy in a selected institution is systematically researched and presented.</p><p><strong>Material and methods: </strong>Numerous patient files from the Bonn sanatorium (Heil- und Pflege-Anstalt Bonn) were analyzed using the historical-critical method. Some of these files contain letters and other testimonies from the patients. This study concentrates on these ego documents and on letters from relatives.</p><p><strong>Results: </strong>While coping with everyday life was central to the patients, some relatives were more concerned with the question of the hereditary nature of the epilepsy; others, who wanted to help their hospitalized relatives were increasingly unable to do so after 1939.</p><p><strong>Conclusion: </strong>Only an overall view of all types of sources in medical records (medical history forms, nursing reports, ego documents and letters from relatives), which has so far often been neglected, enables an approximate understanding of the situation of hospitalized patients with epilepsy during the National Socialist era and the post-war period.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":"272-277"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13171986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mental diseases and driving ability-An update].","authors":"Alexander Brunnauer, Peter Zwanzger, Gerd Laux","doi":"10.1007/s00115-026-01972-5","DOIUrl":"https://doi.org/10.1007/s00115-026-01972-5","url":null,"abstract":"<p><p>Driving has a high priority as it is often a guarantee for participation in professional and social life. For patients as well as for the treating physicians, the topic is associated with great uncertainty and is often proactively not addressed. In Germany the notification of diseases that could limit driving safety or fitness to drive is not mandatory but there is a duty to exercise caution to ensure that safe driving is not impaired by physical or mental illness or by the intake of medications. Treating clinicians, in turn, have a duty to inform the patient; they are required to inform about the risks of the disease, the treatment and potential consequences for daily life. Mental illnesses can restrict driving safety or in some cases even nullify the fitness to drive; however, broad restrictions for patients with a mental illness cannot be derived from empirical data so that a case by case clarification and counselling regarding driving safety and fitness to drive are indicated.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Drug-facilitated sexual violence].","authors":"Harald Dreßing, Andreas Hoell","doi":"10.1007/s00115-026-01973-4","DOIUrl":"https://doi.org/10.1007/s00115-026-01973-4","url":null,"abstract":"","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Is it all bipolar? Differential diagnosis of mood swings in young adulthood].","authors":"Matthias Nieberler, Miriam Appel, Catherina Klüpfel, Wiebke Warrings, Sarah Kittel-Schneider","doi":"10.1007/s00115-026-01970-7","DOIUrl":"https://doi.org/10.1007/s00115-026-01970-7","url":null,"abstract":"<p><strong>Background: </strong>Mood swings can represent a key symptom of various psychiatric disorders in young adulthood. Due to substantial symptom overlap, clinicians often face diagnostic uncertainty, increasing the risk of misdiagnosis and inappropriate treatment.</p><p><strong>Objectives: </strong>Description of qualitative and quantitative characteristics of mood swings in the most relevant psychiatric disorders.</p><p><strong>Materials and methods: </strong>Narrative review based on the International Classification of Diseases, 11th Revision (ICD-11) and pertinent literature.</p><p><strong>Results: </strong>Bipolar affective disorders exhibit episodic, mostly non-reactive mood swings in clearly defined temporary episodes. In unipolar depression, affective changes are predominantly downward-directed and may show diurnal variation. Emotionally unstable personality disorder is characterized by high-frequency, reactive, and interpersonally triggered affective states, whereas neurodevelopmental disorders typically present with situationally induced, short-lived emotional dysregulation.</p><p><strong>Conclusions: </strong>Differential diagnostic evaluation requires a comprehensive clinical assessment, possibly supported by life charts, mood diaries, or psychometric instruments. Given the frequent comorbidities and symptom overlap, a longitudinal diagnostic approach is recommended in cases of uncertainty.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nachruf auf Prof. Dr. med. Stefan Bleich : 17.10.1968–24.02.2026.","authors":"Johannes Kornhuber, Jens Wiltfang","doi":"10.1007/s00115-026-01964-5","DOIUrl":"https://doi.org/10.1007/s00115-026-01964-5","url":null,"abstract":"","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Repetitive intentional foreign body ingestion: Risk of abuse of propofol in endoscopic procedures].","authors":"Elena Böttcher, Tim Papenfuß, Maximilian Gahr","doi":"10.1007/s00115-026-01967-2","DOIUrl":"https://doi.org/10.1007/s00115-026-01967-2","url":null,"abstract":"<p><strong>Background: </strong>Intentional foreign body ingestion (iFBI) represents an increasingly relevant clinical challenge that remains insufficiently evidence based in terms of treatment. Existing somatic (gastroenterologic) and psychiatric care structures may contribute to the maintenance of this behavior.</p><p><strong>Objective: </strong>The aim of the present study is to highlight an aspect of the treatment of iFBI that has received little attention to date: the potential risk of misuse and dependence associated with propofol in the context of repeated endoscopic interventions. Our goal is to raise awareness that for vulnerable patient groups with iFBI such as individuals with borderline personality disorder (BPD), propofol should be considered not only as an anesthetic agent but also as a substance with dependency potential and as a positive dysfunctional reinforcer within complex behavioral patterns.</p><p><strong>Material and methods: </strong>Narrative review of the pharmacological characteristics as well as the potential for misuse and addictive potential of propofol in the context of endoscopic interventions, based on published literature (case reports and retrospective studies).</p><p><strong>Results and discussion: </strong>The literature reports euphoric and anxiolytic effects of propofol related to endoscopic procedures, which may persist beyond the immediate post-procedural period. In addition, a potential risk of propofol misuse and dependence is discussed in the context of endoscopic interventions. When indirect propofol misuse is suspected in the setting of intentional foreign body ingestion (iFBI), alternative sedation strategies should be considered.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mental health status of medical students-A nationwide cross-sectional study].","authors":"Hannah Ramming, Georg Groß, Sophie Bechler, Mareike Lüdtke, Axel Florian Aschenbrenner, Annemarie Kirchgatter, Michael Scholz, Pascal H M Burger, Lena Luibl","doi":"10.1007/s00115-026-01958-3","DOIUrl":"10.1007/s00115-026-01958-3","url":null,"abstract":"<p><strong>Background: </strong>The mental health status of medical students regarding depressive symptoms suicidal ideation and mental stress has become the subject of increasing scientific research; however, in Germany, no nationwide surveys have so far been performed. The present study presents the results from the first nationwide survey on the mental health of medical students in Germany. The aim of this article is to present the general aspects on psychological and physical health as well as specific data regarding depressive symptoms of German medical students. The data were analyzed in a semester-based and gender-based comparison and possible risk or protective factors were evaluated.</p><p><strong>Methods: </strong>Applying an online survey during the COVID-19 pandemic of 8137 medical students from all German medical faculties and study semesters, we collected diverse sociodemographic variables as well as data on psychological and physical health status based on single item measures and questionnaires. Besides sociodemographic information this paper presents data on the physical and mental health status (using single item measures and the Beck Depression Inventory II, BDI-II) as well as correlating influencing factors. Group differences were measured by comparison of mean values and the multivariate dependencies between BDI-II scores and further covariates were analyzed. The survey was completed by 48.3% of the respondents.</p><p><strong>Results: </strong>Of the respondents 13.8% stated that they were not physically healthy and 36.1% stated that they felt mentally unwell. Using the BDI-II questionnaire, at least mild depressive symptoms were identified in 51.1% of respondents in the first semester. Of the respondents 22% reported current suicidal thoughts. Potential risk and protective factors could be identified, which significantly correlated with the BDI-II scores. Among those risk factors were female gender, lower age, physical complaints, need of university support and the presence of a migration background. In contrast, social support, sports and social engagement seem to be potential protective factors.</p><p><strong>Conclusion: </strong>Our analyses showed that medical students have a higher prevalence of depressive symptoms compared to the general population, whereby the survey during the pandemic hindered the direct comparison with pre-pandemic data. The possible risk and protective factors identified can serve as a basis for the development of preventive programs to improve the mental health of medical students.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[DiGA, non-DiGA and realities of practice : A questionnaire study on opportunities and challenges of health apps in the field of mental healthcare].","authors":"Gina Vollert, Bianca Jansky, Ömer Akif, Paul Wolf, Verina Wild","doi":"10.1007/s00115-026-01955-6","DOIUrl":"https://doi.org/10.1007/s00115-026-01955-6","url":null,"abstract":"<p><strong>Background: </strong>Digitalization in the German healthcare system is advancing. Digital services are increasingly being incorporated into mental healthcare.</p><p><strong>Research question: </strong>This questionnaire study examined the assessment of professionals working in mental healthcare regarding the opportunities and challenges of digital health services. It takes digital health applications (DiGA) and non-DiGA (apps and web services without reimbursement and governmental regulation) into account.</p><p><strong>Method: </strong>The online questionnaire included e.g. Likert scales for assessing the success of therapy, the quality of care, the doctor-patient relationship and the willingness to undergo further training. The quantitative questions were supplemented by free text comment fields.</p><p><strong>Results: </strong>Based on 200 participants the analysis shows that a slight majority do not incorporate digital services into their therapy. The majority of respondents stated that digital services can support prevention and psychoeducation; however, whether they could meet the requirements in other areas of psychotherapy was mostly considered questionable. Challenges were largely seen in the high costs and insufficient information available to practitioners. In addition, the risk of exacerbating health inequalities (e.g., due to insufficient digital literacy) was discussed.</p><p><strong>Discussion: </strong>It can be concluded that digital services can certainly add value to mental healthcare; however, the sustainable integration into care is linked to improvements in structural conditions (such as the cost-benefit ratio and better information for those providing treatment) as well as consideration and compensation for socially unequal access conditions.</p>","PeriodicalId":49770,"journal":{"name":"Nervenarzt","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}