{"title":"Study of the Value of Hyperechogenicity and Related Acoustic Features in the Diagnosis of Breast Cancer in Breast Nodules","authors":"","doi":"10.23977/medsc.2023.040710","DOIUrl":"https://doi.org/10.23977/medsc.2023.040710","url":null,"abstract":"To invest the diagnostic value of hyperecho and related acoustic features in break schedules in break cancer. The ultrasonic features of 90 cases of hyperechoic break schedules confirmed by pathology were retrospectively analyzed, including 49 cases of the sign group and 41 cases of the minor group. The ultra-graphic features of the two groups were compared and observed, including morphology, orientation, edge, calibration, interior echo, blood supply, hyperechoic Corona, etc. Multivariate Logistic regression model was used to screen the risk ultra sound signals of hyperechoic break schedules. ROC curve was drawn to evaluate the diagnostic validity of ultrasound for hyperechoic break rules by AUC. There were statistically significant differences in the morphology, orientation, margin, calibration, and echo halos between the two groups (x ²= 14.504, 5.511, 42.643, 9.870, 26.071, all P<0.05). There were no statistically significant differences in the posterior echo and blood supply (x ²= /, 2.089, P>0.05). The Multivariate Logistic regression model was shown that margin unbalances and microcalculation were the risk ultra sound signals of hyperechoic break schedules. The ROC curve was drawn based on the probability value of this model to predict hyperechoic break cancer, and the AUC was 0.912, the sensitivity was 0.829, the specificity was 0.918. Marginal unconsolidation and microcalcification are important ultra-signs of hyperechoic break nodules, which have high value in predicting hyperechoic break cancer.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application progress of pelvic floor ultrasound in acupuncture treatment of female stress urinary incontinence","authors":"","doi":"10.23977/medsc.2023.040510","DOIUrl":"https://doi.org/10.23977/medsc.2023.040510","url":null,"abstract":"As the prevalence of female stress urinary incontinence (SUI) increases year by year, acupuncture, as one of the non-surgical treatment methods of Sui, has significant clinical efficacy and is worthy of promotion and application in clinical treatment. As a noninvasive, convenient, low-cost and highly acceptable imaging method, pelvic floor ultrasound can accurately and clearly observe the pelvic floor structure of patients, provide objective imaging data for clinical diagnosis and evaluation, and clearly evaluate the clinical efficacy of acupuncture in the treatment of Sui. This article mainly discusses the application progress of pelvic floor ultrasound in the treatment of female stress urinary incontinence with acupuncture.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135502132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on the value of comprehensive perioperative nursing management for patients undergoing surgery for acromioclavicular joint dislocation","authors":"","doi":"10.23977/medsc.2023.040711","DOIUrl":"https://doi.org/10.23977/medsc.2023.040711","url":null,"abstract":"The clinical value of comprehensive perioperative nursing management in the care of patients with acromioclavicular joint dislocation was analyzed. 62 patients with acromioclavicular joint dislocation who underwent surgery in our hospital from January 2020 to December 2022 were selected and randomly divided into two groups of 31 patients. The nursing methods included routine nursing management (control group) and comprehensive perioperative nursing management (observation group), and the clinical efficacy, pain, joint function, and nursing satisfaction after nursing were evaluated. The excellent treatment rate of the observation group (96.77%) was higher than the control group (80.65%), the difference (P <0.05). The VAS and VRS scores in the observation group were lower than those in the control group, the difference (P <0.05). ASES and Constant-Murley scores in the observation group were higher than those in the control group, the difference (P <0.05). The nursing satisfaction of the observation group (100.00%) showed a higher difference compared to the control group (87.10%), the difference (P<0.05). Perioperative comprehensive nursing management has a remarkable effect on acroioclavicular joint dislocation surgery, which can ensure the surgical effect, reduce postoperative pain and promote the recovery of joint function, which is worthy of promotion.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Nursing Care of Patients with Intestinal Obstruction after Laparoscopic Surgery for Hysteromyoma","authors":"","doi":"10.23977/medsc.2023.040604","DOIUrl":"https://doi.org/10.23977/medsc.2023.040604","url":null,"abstract":"To explore the nursing experience of patients with intestinal obstruction after laparoscopic surgery for uterine fibroids. 30 patients with hysteromyoma and intestinal obstruction after laparoscopic surgery were selected, and effective nursing intervention was taken after symptomatic treatment. 30 patients were cured after conservative treatment. The cure time was 7-14 days, with an average of 10.5 days. Effective nursing intervention for patients with intestinal obstruction after laparoscopic surgery for hysteromyoma can promote the recovery of intestinal function, which is conducive to the later rehabilitation of patients, and is worthy of clinical promotion.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135843748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of Radiation Enteritis and Progress in Treatment of Traditional Chinese and Western Medicine","authors":"","doi":"10.23977/medsc.2023.040705","DOIUrl":"https://doi.org/10.23977/medsc.2023.040705","url":null,"abstract":"Radiation enteritis (RE) is one of the most severe and common complications of abdominal or pelvic tumor radiation therapy. The affected intestinal lesions are extensive, with complex pathological manifestations, severely affecting the quality of life of cancer patients after radiotherapy. However, currently there are few clinical drug treatment methods and the effects are not satisfactory, and the related basic research and new drug development are still unclear. This article reviews the relevant literature in recent years, summarizes and analyzes the pathological mechanisms, treatment strategies, and the understanding and treatment methods of radiation enteritis in Western medicine, in order to provide ideas and directions for the prevention and treatment strategies and drugs of radiation enteritis research.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploration of the Mechanism of Zhongzhu Acupoint for the Treatment of Tinnitus Syndrome","authors":"","doi":"10.23977/medsc.2023.040620","DOIUrl":"https://doi.org/10.23977/medsc.2023.040620","url":null,"abstract":"Zhongzhu Point is often used in clinical treatment of tinnitus.However, at present, the mechanism of Zhongzhu acupoint in the treatment of tinnitus is not fully and clearly understood. This article expounds the effective mechanism of Zhongzhu point for tinnitus treatment from ancient medical books, traditional Chinese medicine meridian and five elements theory of Zangfu organs, modern disarticulation, different treatment methods, including acupuncture, electroacupuncture, moxibustion, modern imaging, etc. It fully shows that Zhongzhu point has clinical rationality and modern science and technology research support for the treatment of tinnitus, and puts forward a new research idea for the treatment of tinnitus.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observations on the safety of precision anesthesia techniques in surgery for elderly patients","authors":"","doi":"10.23977/medsc.2023.040709","DOIUrl":"https://doi.org/10.23977/medsc.2023.040709","url":null,"abstract":"This study aims to explore the application effect of precision anesthesia in elderly surgical patients. 82 elderly patients who underwent surgical treatment in our hospital from September 2021 to August 2023 were selected as the research subjects. The patients were divided into an observation group and a control group using a random table method, with 41 cases in each group. The control group used traditional anesthesia techniques for anesthesia management. The observation group used precision anesthesia technology to anesthetize patients. Compare the depth of anesthesia control, incidence of complications during anesthesia, and postoperative recovery between the two groups. The control group using precise anesthesia technology for anesthesia management was significantly better than the control group in terms of anesthesia control depth, incidence of complications during anesthesia, and postoperative recovery rate (p<0.05), promoting postoperative recovery and improving the prognosis of elderly patients during surgery. It has good safety and high clinical value, and is worth further research and promotion.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135450485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Causal Associations of Hypothyroidism with Prostate Cancer, Colorectal Cancer and Lung Cancer: A Mendelian Randomization Study","authors":"","doi":"10.23977/medsc.2023.040607","DOIUrl":"https://doi.org/10.23977/medsc.2023.040607","url":null,"abstract":"Previous observational studies have suggested that hypothyroidism may affect the risk of cancer. However, the causal effects were still unclear and controversary. Therefore, a two-sample Mendelian randomization (MR) analysis was conducted to evaluate the association between hypothyroidism and six types of cancer, including colorectum, pancreas, prostate, lung, bladder and stomach cancer. The inverse variance weighted (IVW), MR-Egger and Weighted Media were carried out to estimate the relation in the MR analysis. Different approaches such as leave-one-out analysis and MR-PRESSO for sensitivity analyses were used to assess the stability of the results. The MR results showed that hypothyroidism was causally associated with decreased risk of lung cancer (OR [odds ratio] = 0.19, P= 0.007), colorectal cancer (OR = 0.27, P= 0.016) and prostate cancer (OR = 0.18, P= 7.44e-05). Significant association between hypothyroidism and the risk of bladder cancer, stomach cancer and pancreas were not found with IVW P>0.05. These results indicated that hypothyroidism can decrease the risk of lung cancer, colorectal cancer and prostate cancer. But evidence of the association between hypothyroidism and other three types of cancer was not found in our study. Further research is necessary to clarify the relation.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136258188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on the application of dexmedetomidine in general anesthesia in elderly patients","authors":"","doi":"10.23977/medsc.2023.040619","DOIUrl":"https://doi.org/10.23977/medsc.2023.040619","url":null,"abstract":": Dexmedetomidine is a highly selective a2-adrenergic agonist with sedative, anxiolytic, and anti-sympathetic properties as well as hemodynamic stabilization, and is widely used in all phases of the perianesthesia period without significant effects on patient respiration. In elderly surgical patients, because of their age, degenerative changes in the autonomic nervous system and more comorbidities, dexmedetomidine anesthesia can effectively slow down intestinal motility and prevent various postoperative symptoms, better protect patients' cardiovascular and cerebrovascular, reduce the incidence of cardiovascular and cerebrovascular adverse events, and stabilize patients' hemodynamics. Compared with traditional opioids, dexmedetomidine is safer and more effective. This study reviews the advantages and specifics of dexmedetomidine in the anesthesia of elderly patients.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"263 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134884602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ferroptosis: Emerging mechanisms, biology and hallmarks","authors":"","doi":"10.23977/medsc.2023.040608","DOIUrl":"https://doi.org/10.23977/medsc.2023.040608","url":null,"abstract":": Ferroptosis is a new type of cell death which is iron-dependent and caused by lipid peroxidation, distinguished from apoptosis, necrosis, pyroptosis, and autophagy. The occurrence of ferroptosis is determined by the balance between the ferroptosis execution systems and the ferroptosis defense systems. The ferroptosis execution system includes iron metabolism, lipid metabolism, mitochondrial metabolism, etc., which induces ferroptosis by promoting the production of ROS. The ferroptosis resistance system is mainly comprised of antioxidants such as GPX4 and coenzyme Q (CoQ), which eleminate ROS and suppress ferroptosis. After cells undergo ferroptosis, morphological, biochemical, genetic, immune, and other changes occur. This review focuses on the molecular mechanism and characteristics of ferroptosis, and analyzes the potential problems as well as directions of its future research.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136304892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}