MEDS Clinical Medicine最新文献

Research Progress on Social Avoidance and Distress in Stroke Patients 脑卒中患者社交回避与焦虑的研究进展

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040704

{"title":"Research Progress on Social Avoidance and Distress in Stroke Patients","authors":"","doi":"10.23977/medsc.2023.040704","DOIUrl":"https://doi.org/10.23977/medsc.2023.040704","url":null,"abstract":"This study reviewed the research on social avoidance and distress in stroke patients for future research. This study reviewed and summarized the research on social avoidance and distress in stroke patients. This paper analyzed the research status, evaluation tools, influencing factors, and intervention methods of social avoidance and distress in stroke patients, and suggested directions for future research. Social avoidance and distress are common among stroke patients, and there is currently a lack of tools to assess social avoidance and distress. Gender, age, clinical biological indicators, stroke sequelae, psychological factors, social support, and social discrimination are influencing factors for social avoidance and distress in stroke patients. Social avoidance and distress can be alleviated by self-management, health empowerment intervention, and implementing mindfulness-based stress reduction therapy. Social avoidance and distress seriously affect the quality of life of stroke patients and are detrimental to their social lives. Hence, it is necessary to develop assessment tools to evaluate social avoidance and distress for stroke patients. Additionally, it is important to continuously improve social support systems and health education to motivate and reintegrate stroke patients into society.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Effect Observation of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Spinal Fractures in the Elderly 经皮椎体成形术治疗老年骨质疏松性脊柱骨折的临床疗效观察

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040703

{"title":"Clinical Effect Observation of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Spinal Fractures in the Elderly","authors":"","doi":"10.23977/medsc.2023.040703","DOIUrl":"https://doi.org/10.23977/medsc.2023.040703","url":null,"abstract":"The clinical efficacy of percutaneous vertebroplasty in the treatment of osteoporotic spinal fractures in the elderly was observed. 86 cases of elderly osteoporotic spine fracture patients admitted to our hospital from January 2021 to June 2023 were selected as study subjects and randomly divided into the control group and the study group. In the control group, 43 cases were given traditional conservative treatment; in the study group, 43 cases were given percutaneous vertebroplasty. The vertebral body indexes of the two groups before and after treatment were compared, including anterior margin height, midline height, posterior margin height and posterior convexity angle; the quality of life of the two groups was compared, including social function, emotional function, cognitive function and somatic function; and the treatment satisfaction of the two groups was compared. The comparison of vertebral indexes between the two groups before treatment was not obvious, and there was no comparison significance in all four indexes, p>0.05; after treatment, the anterior margin height, midline height, posterior margin height, and posterior convexity angle of the study group were significantly better than that of the control group, p<0.05; the scores of the study group's social functioning, emotional functioning, cognitive functioning, and somatic functioning were significantly higher than those of the control group, p<0.05; and the study group's total satisfaction rate was 97.67%, which was higher than 81.40% in the control group, p<0.05. Percutaneous vertebroplasty has a better clinical effect in the treatment of osteoporotic spinal fracture in the elderly, which is worthy of popularization.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the Influence of Virus Infection on the Treatment Strategy of Rheumatoid Arthritis and Systemic Lupus Erythematosus 病毒感染对类风湿关节炎和系统性红斑狼疮治疗策略影响的研究

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040707

{"title":"Study on the Influence of Virus Infection on the Treatment Strategy of Rheumatoid Arthritis and Systemic Lupus Erythematosus","authors":"","doi":"10.23977/medsc.2023.040707","DOIUrl":"https://doi.org/10.23977/medsc.2023.040707","url":null,"abstract":"The purpose of this study is to explore the influence of virus infection on the treatment strategy of rheumatoid arthritis and systemic lupus erythematosus. In order to systematically explore the influence of virus infection on the treatment strategy of rheumatoid arthritis and systemic lupus erythematosus, our research adopts the methods of literature review, clinical trial, and data analysis. First of all, the literature on the relationship between rheumatoid arthritis, systemic lupus erythematosus, and viral infection will be comprehensively searched, and we will conduct in-depth analysis and evaluation. Secondly, clinical trials will be designed and implemented to verify the efficacy of the treatment strategy for viral infection on rheumatoid arthritis and systemic lupus erythematosus. Finally, the research results will be processed and explained by statistical analysis methods. Studies have shown that viral infection has an important influence on the treatment strategy of rheumatoid arthritis and systemic lupus erythematosus. For patients with rheumatoid arthritis, the prevention and treatment of viral infection may help to slow down the progress of the disease. For patients with systemic lupus erythematosus, the treatment strategy for viral infection may be helpful to improve the prognosis of patients. Our aim is to provide new ideas and methods for clinical treatment.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135446820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical efficacy research of arthroscopy-assisted closed reduction-guided internal fixation of patella fractures 关节镜辅助下闭合复位引导髌骨骨折内固定的临床疗效研究

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040708

{"title":"Clinical efficacy research of arthroscopy-assisted closed reduction-guided internal fixation of patella fractures","authors":"","doi":"10.23977/medsc.2023.040708","DOIUrl":"https://doi.org/10.23977/medsc.2023.040708","url":null,"abstract":"To investigate the clinical effect of arthroscopic assisted closed reduction guide guided internal fixation for patellar fractures, and its role in improving treatment efficiency and promoting patient recovery. This study included a total of 120 patients who underwent arthroscopic assisted closed reduction guided internal fixation treatment for patellar fractures between 2018 and 2023[1]. They were divided into an observation group (n=60) and a control group (n=60) according to the treatment method. The observation group received arthroscopic assisted closed reduction guided internal fixation treatment, while the control group received traditional surgical treatment. Collect and compare indicators such as fracture healing time, incidence of complications, and postoperative functional scores between two groups of patients. The fracture healing time was significantly earlier (P<0.05), and the incidence of complications was significantly reduced compared to the control group (P<0.05)[2]. The postoperative functional score in the observation group was significantly better than that in the control group (P<0.05), indicating that arthroscopic assisted closed reduction guided internal fixation therapy has significant advantages in improving treatment efficiency and promoting patient recovery. Arthroscopic assisted closed reduction guided internal fixation can effectively improve the surgical efficiency and treatment effect of patients with patellar fractures, reduce the incidence of complications, promote patient recovery, and is worthy of clinical promotion and application.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"68 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135450728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application and Development of Digital Technology in Dental Restoration 数字技术在口腔修复中的应用与发展

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040606

引用次数: 0

Study on Efficacy of Modified Headache Formula I on Patients with Migraine and Its Improvement on Free Radical Disorder 头痛加减方1对偏头痛患者的疗效及对自由基紊乱的改善作用研究

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040609

引用次数: 0

Exploration on the mechanism of quercetin in treating breast duct dilation based on network pharmacology 基于网络药理学的槲皮素治疗乳腺导管扩张的机制探讨

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040613

{"title":"Exploration on the mechanism of quercetin in treating breast duct dilation based on network pharmacology","authors":"","doi":"10.23977/medsc.2023.040613","DOIUrl":"https://doi.org/10.23977/medsc.2023.040613","url":null,"abstract":"Dilation of mammary duct is a chronic nonbacterial inflammation of the breast based on breast duct obstruction, secondary breast duct dilation, periductal inflammation, and plasma cell infiltration.Dilation of mammary duct is a chronic nonbacterial inflammation of the breast based on breast duct obstruction, secondary breast duct dilation, periductal inflammation, and plasma cell infiltration. To analyze the mechanism of quercetin in the treatment of Dilation of mammary duct based on network pharmacology and further explore the modern pharmacological action of quercetin, The related targets of \"quercetin\" were screened from the TCMSP database; Relevant targets of \" Dilation of mammary duct were screened from Genecards database. After the common protein target information of the two was obtained through venny, the protein interaction network was constructed using Cytoscape software, and the hub gene was screened. Use David platform to conduct GO, KEGG and other enrichment analysis on the same targe. Conclusion: There are138 nodes and 2608 edges in the PPI network. These targets mainly include AKT1, IL-6, TP53, TNF, VEGFA, CASP3, IL1B, EGFR, JUN, etc. The results of GO enrichment analysis showed that quercetin is involved in 666 biological processes, 98 cellular composition, and 128 molecular functions. It mainly plays a role in AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer, Lipid and atherosclerosis, and other pathways, Conclusion: Quercetin exerts anti-inflammatory effects in Dilation of mammary duct through multiple pathways and multiple targets, which is a new option for the treatment of Dilation of mammary duct.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"27 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135157413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploration on the clinical effect of external fixation with homemade splints in the treatment of metacarpal fractures 自制夹板外固定治疗掌骨骨折的临床疗效探讨

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040702

引用次数: 0

Clinical Research Progress of Chinese Medicine in the Treatment of Insomnia of Heart-Kidney Disorder 中医治疗心肾疾患性失眠的临床研究进展

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040511

引用次数: 0

Correlation between Gal-3, Klotho, Calcium and Phosphorus Metabolism Indicators and Cardiovascular Complications in Non Dialysis Patients with Chronic Kidney Disease 非透析慢性肾病患者Gal-3、Klotho、钙磷代谢指标与心血管并发症的相关性

MEDS Clinical Medicine Pub Date : 2023-01-01 DOI: 10.23977/medsc.2023.040520

{"title":"Correlation between Gal-3, Klotho, Calcium and Phosphorus Metabolism Indicators and Cardiovascular Complications in Non Dialysis Patients with Chronic Kidney Disease","authors":"","doi":"10.23977/medsc.2023.040520","DOIUrl":"https://doi.org/10.23977/medsc.2023.040520","url":null,"abstract":"This article explores the correlation between Gal-3, Klotho, calcium and phosphorus metabolism indicators and cardiovascular disease in non dialysis CKD (stage 3-5) patients, summarizes their clinical characteristics, and provides a basis for the prevention and treatment of cardiovascular disease caused by CKD in clinical practice, providing reference for related research. This article selects 100 patients with stage 3-5 CKD who have not received renal replacement therapy. This question involves collecting general data from patients, collecting blood samples from patients, detecting serum calcium, serum phosphorus, Gal-3, and PTH levels at different stages, and calculating the product of calcium and phosphorus. Meanwhile, this study compared the incidence of hypocalcemia, hyperphosphatemia, and hyperparathyroidism at different stages. The research results showed that there was no statistically significant difference in blood calcium levels between CKD3 patients in stages 3 and 4 (P>0.05), but the blood calcium levels of CKD3 patients were significantly lower than those in stages 3 and 4. The difference between the two groups was statistically significant (P<0.05). The calcium and phosphorus products and PTH of patients in different stages gradually increased, but there was no significant difference in ALP levels in different stages (P>0.05). The incidence of hypocalcemia, hyperphosphatemia, high PTH, and calcium phosphate products>55 showed significant differences (P<0.01), and showed an increasing trend with stages, with the lowest in stage 3 and the highest in stage 5. This article analyzes the serum levels of Gal-3, Klotho, and calcium and phosphorus in non dialysis patients with CKD, which has important guiding significance for preventing cardiovascular complications, early intervention, and reducing patient mortality.","PeriodicalId":497271,"journal":{"name":"MEDS Clinical Medicine","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135502127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0