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Seminars in Neurology最新文献

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Maisha T. Robinson, MD, and Claire J. Creutzfeldt, MD. Maisha T.罗宾逊（Robinson）医学博士和克莱尔-J-克雷兹费尔特（Claire J. Creutzfeldt）医学博士。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-10-01 Epub Date: 2024-10-17 DOI: 10.1055/s-0044-1790540
David M Greer
{"title":"Maisha T. Robinson, MD, and Claire J. Creutzfeldt, MD.","authors":"David M Greer","doi":"10.1055/s-0044-1790540","DOIUrl":"https://doi.org/10.1055/s-0044-1790540","url":null,"abstract":"","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":"44 5","pages":"481-482"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Trends in Neuropalliative Care: A Palliative Approach to Epilepsy and Seizure Management in Adults. 神经姑息治疗的新趋势：成人癫痫和癫痫发作的姑息治疗方法》（A Palliative Approach to Epilepsy and Seizure Management in Adults）。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI: 10.1055/s-0044-1787808
Anna-Christin Willert, Alexander Bernhard Kowski
{"title":"Emerging Trends in Neuropalliative Care: A Palliative Approach to Epilepsy and Seizure Management in Adults.","authors":"Anna-Christin Willert, Alexander Bernhard Kowski","doi":"10.1055/s-0044-1787808","DOIUrl":"10.1055/s-0044-1787808","url":null,"abstract":"<p><p>Management of severe (drug-resistant) epilepsy and epilepsy in other serious illnesses is multidimensional and requires consideration of both physical symptoms and psychosocial distress that require individualized treatment. Palliative care offers a holistic approach to disease that focuses on all dimensions of suffering to maintain quality of life. Integration of a palliative care mind- and skillset in the management of severe epilepsy and epilepsy in other serious illnesses can provide person-centered care and support for families and caregivers.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"567-573"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Ethical Dimensions in Neuropalliative Care. 探索神经姑息治疗中的伦理问题。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI: 10.1055/s-0044-1787775
Annie L Gula, Jennifer K Walter, Wynne Morrison, Matthew P Kirschen
{"title":"Exploring Ethical Dimensions in Neuropalliative Care.","authors":"Annie L Gula, Jennifer K Walter, Wynne Morrison, Matthew P Kirschen","doi":"10.1055/s-0044-1787775","DOIUrl":"10.1055/s-0044-1787775","url":null,"abstract":"<p><p>Neurologic illnesses can be challenging to diagnose, involve changes in consciousness, and are often complicated by prognostic uncertainty. These disorders can affect how individuals interact with their environment, and as a result, many ethical concerns may arise related to their medical care. Key ethical issues in neuropalliative care include shared decision-making, evolving autonomy and capacity, best interest and harm principles, beneficence and nonmaleficence, futile and inappropriate care, justice and equity, and ableism. The four core principles of medical ethics, beneficence, nonmaleficence, justice, and autonomy, are foundational in considering approaches to these ethical challenges. Shared decision-making is rooted in the principle of autonomy. Evolving autonomy and capacity evoke autonomy, beneficence, and nonmaleficence. The best interest and harm principles are rooted in beneficence and nonmaleficence. Questions of futility and inappropriate care are founded in the principles of nonmaleficence, autonomy, and justice. Ableism invokes questions of nonmaleficence, autonomy, and justice. Practitioners of neurology will encounter ethical challenges in their practice. Framing decisions around the core ethical principles of beneficence, nonmaleficence, autonomy, and justice will help clinicians navigate challenging situations while acknowledging and respecting each patient's individual story.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"534-542"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Neurologic Illness: Skills in Neuropalliative Care for Persons Hospitalized with Neurologic Disease. 导航神经系统疾病：神经系统疾病住院患者的神经姑息治疗技巧》。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-10-01 Epub Date: 2024-07-25 DOI: 10.1055/s-0044-1788723
Andrew P Huang, Robert G Holloway
{"title":"Navigating Neurologic Illness: Skills in Neuropalliative Care for Persons Hospitalized with Neurologic Disease.","authors":"Andrew P Huang, Robert G Holloway","doi":"10.1055/s-0044-1788723","DOIUrl":"10.1055/s-0044-1788723","url":null,"abstract":"<p><p>Persons hospitalized for neurologic illness face multidimensional care needs. They can benefit from a palliative care approach that focuses on quality of life for persons with serious illness. We describe neurology provider \"skills\" to help meet these palliative needs: assessing the patient as a whole; facilitating conversations with patients to connect prognosis to care preferences; navigating neurologic illness to prepare patients and care partners for the future; providing high-quality end-of-life care to promote peace in death; and addressing disparities in care delivery.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"503-513"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathways to Neuropalliative Care Practice. 神经姑息治疗实践之路。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-10-01 Epub Date: 2024-07-02 DOI: 10.1055/s-0044-1787807
Eileen Harrigan, Hannah L Kirsch, Kwame Adjepong, Rita Caroline Crooms
{"title":"Pathways to Neuropalliative Care Practice.","authors":"Eileen Harrigan, Hannah L Kirsch, Kwame Adjepong, Rita Caroline Crooms","doi":"10.1055/s-0044-1787807","DOIUrl":"10.1055/s-0044-1787807","url":null,"abstract":"<p><p>As neuropalliative care is better recognized and more widely utilized, there is as great a need for clinicians trained in the field as there is for disease-specific symptom management, advance care planning, and end-of-life care. In this manuscript, we describe potential career trajectories in neuropalliative care. For clinicians, this includes educational and training opportunities within primary neuropalliative care (integrating palliative care principles into usual neurology practice), specialty neuropalliative care (completing a hospice and palliative medicine fellowship), and hospice. We also describe considerations for establishing new clinical neuropalliative practices and highlight neuropalliative education and research as key areas for advancing the field.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"543-550"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurological Complications of Cannabinoids. 大麻素的神经并发症。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-08-01 Epub Date: 2024-06-24 DOI: 10.1055/s-0044-1787570
Mariyam Humayun, Jose I Suarez, Vishank A Shah
{"title":"Neurological Complications of Cannabinoids.","authors":"Mariyam Humayun, Jose I Suarez, Vishank A Shah","doi":"10.1055/s-0044-1787570","DOIUrl":"10.1055/s-0044-1787570","url":null,"abstract":"<p><p>Cannabinoid use, particularly for recreational purposes, is increasing exponentially across all age groups, especially in younger populations, due to its perceived low risk and legalization. While cannabinoids may be largely considered as safe, there is mounting evidence of increased risk of systemic and neurological complications through their interaction with the poorly understood endocannabinoid receptor network within the central nervous system and other organ systems. Acute cannabinoid exposure can cause neuropsychiatric symptoms in addition to altering cerebral blood flow, leading to cerebrovascular complications such as ischemic stroke, subarachnoid hemorrhage, and reversible cerebral vasoconstriction syndrome (RCVS). Chronic use, particularly among adolescents, may be associated with increased risk of long-term cognitive deficits, schizophrenia, and other neuropsychiatric effects. Synthetic cannabinoids have increased potency, with reports of causing profound neurological complications including coma, seizures, posterior reversible encephalopathy syndrome, and RCVS. Despite increasing evidence, the quality of literature describing neurologic complications with cannabinoids remains limited to case series and retrospective cohort studies, with significant confounding factors such as concomitant use of other illicit drugs, limiting interpretation. In this review, we summarize the effect of cannabinoids on the neurologic system and associated neurological complications.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"430-440"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opioid-Associated Nervous System Injuries. 阿片类药物相关神经系统损伤。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-08-01 Epub Date: 2024-06-07 DOI: 10.1055/s-0044-1787545
Kim Griffin, Derek Stitt
{"title":"Opioid-Associated Nervous System Injuries.","authors":"Kim Griffin, Derek Stitt","doi":"10.1055/s-0044-1787545","DOIUrl":"10.1055/s-0044-1787545","url":null,"abstract":"<p><p>With the rise of the opioid epidemic, the practicing neurologist must recognize the patterns of a growing number of opioid-associated neurological injuries. This is in addition to the classic toxidrome of miosis, altered mental status, and respiratory depression, which must never be overlooked, as it is reversible and potentially lifesaving. Several other idiosyncratic syndromes due to opioid-related nervous system insults are defined by their characteristic imaging findings and portend variable functional recovery. Opioid toxicity can not only lead to brain injury, but also spinal cord and, rarely, peripheral nerve injury. As several newer synthetic opioids are undetectable by most assays, a low threshold to suspect opioid exposure must be maintained.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"452-458"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Derek Stitt, MD, and Justin McArthur MBBS, MPH, FAAN. 医学博士德里克-斯蒂特（Derek Stitt）和医学博士、公共卫生硕士、FAAN 贾斯汀-麦克阿瑟（Justin McArthur）。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-08-01 Epub Date: 2024-07-16 DOI: 10.1055/s-0044-1787573
David M Greer
{"title":"Derek Stitt, MD, and Justin McArthur MBBS, MPH, FAAN.","authors":"David M Greer","doi":"10.1055/s-0044-1787573","DOIUrl":"https://doi.org/10.1055/s-0044-1787573","url":null,"abstract":"","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":"44 4","pages":"413"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141628166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Availability and Opportunities for Expansion of Buprenorphine for the Treatment of Opioid Use Disorder. 用于治疗阿片类药物使用障碍的丁丙诺啡的可用性和推广机会。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-08-01 Epub Date: 2024-06-14 DOI: 10.1055/s-0044-1787569
Greer McKendrick, Samuel W Stull, Anjalee Sharma, Kelly E Dunn
{"title":"Availability and Opportunities for Expansion of Buprenorphine for the Treatment of Opioid Use Disorder.","authors":"Greer McKendrick, Samuel W Stull, Anjalee Sharma, Kelly E Dunn","doi":"10.1055/s-0044-1787569","DOIUrl":"10.1055/s-0044-1787569","url":null,"abstract":"<p><p>There is an urgent need to expand access to treatment for persons with opioid use disorder (OUD). As neurologists may frequently encounter patients with chronic pain who have developed OUD, they are in a position to serve as advocates for treatment. Buprenorphine is the most scalable medication for OUD in the United States, yet expansion has plateaued in recent years despite growing treatment needs. Reluctance of providers to establish treatment with new patients, challenges with rural expansion, stigma related to buprenorphine-based care, and pharmacy pressures that incentivize low dispensing and inventories may have stalled expansion. This review introduces these challenges before outlining actionable and evidenced-based strategies that warrant investigation, including methods to improve patient access to care (remotely delivered care, mobile delivery programs, Bridge programs) and provider retention and confidence in prescribing (expert consults, Extension for Community Healthcare Outcomes, a telementoring model, hub-and-spoke services), as well as novel innovations (virtual reality, artificial intelligence, wearable technologies). Overall, fortifying existing delivery systems while developing new transformative models may be necessary to achieve more optimal levels of buprenorphine treatment expansion.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"419-429"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substance Use Disorder Treatment: Opportunities for Interdisciplinary Collaboration in Neurology and Beyond. 药物使用障碍治疗：神经病学及其他学科的跨学科合作机会。
IF 1.8 4区 医学
Seminars in Neurology Pub Date : 2024-08-01 Epub Date: 2024-06-18 DOI: 10.1055/s-0044-1787654
Kenneth B Stoller
{"title":"Substance Use Disorder Treatment: Opportunities for Interdisciplinary Collaboration in Neurology and Beyond.","authors":"Kenneth B Stoller","doi":"10.1055/s-0044-1787654","DOIUrl":"10.1055/s-0044-1787654","url":null,"abstract":"<p><p>Driving the overdose epidemic, a significant proportion of adult and adolescent patients seen in neurology practice and hospital settings has substance use disorder. Fortunately, there are effective treatments available, in particular for opioid addiction. Some elements of treatment can be delivered directly in medical office-based settings, while others are best provided from within specialized addiction treatment facilities. In this article, we review the nature of substance use disorders, and the various treatment approaches that can be utilized to stabilize patients and facilitate their building a strong recovery foundation. Some interventions discussed may be directly provided by a physician identifying the disorder, while others involve collaboration with specialized addiction treatment centers and recovery support entities.</p>","PeriodicalId":49544,"journal":{"name":"Seminars in Neurology","volume":" ","pages":"471-479"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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