{"title":"Danksagung an die Gutachter / Acknowledgement for Reviewers.","authors":"","doi":"10.1055/a-2200-9662","DOIUrl":"10.1055/a-2200-9662","url":null,"abstract":"","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 6","pages":"385"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra Richter, Ulrike Stursberg, Isabella Pfeiffer, Gerhard Loesenbeck, Carola Sauter-Louis, Katrin Hartmann, Ralf S Mueller, Renè Doerfelt, Bianka S Schulz
{"title":"Intradermal testing and serum allergen-specific IgE-testing in cats with naturally occurring feline bronchial disease.","authors":"Petra Richter, Ulrike Stursberg, Isabella Pfeiffer, Gerhard Loesenbeck, Carola Sauter-Louis, Katrin Hartmann, Ralf S Mueller, Renè Doerfelt, Bianka S Schulz","doi":"10.1055/a-2190-4139","DOIUrl":"10.1055/a-2190-4139","url":null,"abstract":"<p><strong>Objectives: </strong>While feline asthma (FA) is considered to be of allergic origin, the etiology of feline chronic bronchitis (CB) to date is unknown. Aim of the study was to compare the results of intradermal testing (IDT) and serum testing for allergen-specific immunoglobulin E (SAT) in cats diagnosed with FA and CB.</p><p><strong>Material and methods: </strong>Twenty-seven client-owned cats with clinical signs, suggestive of feline inflammatory bronchial disease (FBD) were prospectively enrolled in the study. Patients were assigned to 3 groups based on results of bronchoalveolar-lavage-fluid (BALF)-cytology: FA (n=8), CB (n=10), or cats with a physiological BALF cytology (PB; n=9). A standardized IDT for 27 allergens was performed in all cats. In addition, allergen-specific IgE was measured in serum samples using an FcεRIα-ELISA. The number of positive reactions in both tests was compared between groups, and agreement between test results of both tests was evaluated.</p><p><strong>Results: </strong>Regarding the number of positive reactions, no statistically significant difference was detected between groups in IDT (p=0.65) and SAT (p=0.51). When comparing the 2 test systems, a weak correlation was found for the allergens <i>Tyrophagus putrescentiae</i> (k=0.256), <i>Dermatophagoides farinae</i> (k=0.276), and rye (k=0.273). The most commonly observed reactions were to house dust mites, storage mites, rye and nettle in IDT and to sheep sorrel, storage mites, and house dust mites in SAT.</p><p><strong>Conclusion and relevance: </strong>IDT and SAT in cats with feline inflammatory bronchial disease (FBD) cannot be used interchangeably for allergen detection. Sensitization to environmental allergens can occur in cats with and without airway inflammation. Therefore, a positive test result should always be assessed in context with clinical signs and allergen exposure.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 6","pages":"403-410"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix Lackmann, Thomas Rohwedder, Anita Maron, Ludo Stegen, Mathias Brunnberg, Leo Brunnberg, Michael Burger, Peter Böttcher
{"title":"Quantification of skin wound tension using a newly designed wound tensiometer.","authors":"Felix Lackmann, Thomas Rohwedder, Anita Maron, Ludo Stegen, Mathias Brunnberg, Leo Brunnberg, Michael Burger, Peter Böttcher","doi":"10.1055/a-2150-0587","DOIUrl":"10.1055/a-2150-0587","url":null,"abstract":"<p><strong>Objective: </strong>To (i) quantitatively measure wound tension in experimental skin wounds using a newly developed wound tensiometer and (ii) establish reference values for primary skin wound closure in medium- and large-breed dogs.</p><p><strong>Study design: </strong>Experimental cadaveric study.</p><p><strong>Animal population: </strong>Nineteen dogs of medium to large breeds (BW 20 to 40 kg).</p><p><strong>Methods: </strong>Elliptical skin wounds of different sizes were created on the chest and abdomen. The wounds were gradually enlarged. Experienced surgeons (ECVS diplomates or professors of small animal surgery) and inexperienced surgeons (1st year after graduation) independently assessed wound tension through manual manipulation and determined whether the wound could be closed without tension-relieving measures. In addition, wound tension was objectively quantified using a newly developed wound tensiometer.</p><p><strong>Results: </strong>The upper threshold for wound tension at which direct appositional wound closure was recommended by the experienced surgeons was 5.4 N, and the median minimal tension without recommendations for closure was 6.0 N. The data also demonstrate that wound tension and wound size do not necessarily correlate, and inexperienced surgeons need to develop a feel for wound tension.</p><p><strong>Conclusion: </strong>The intraoperative use of the wound tensiometer, in combination with established cut-off values, might facilitate decision-making regarding primary wound closure.</p><p><strong>Clinical relevance: </strong>The findings of this study provide evidence for the applicability of a wound tensiometer in guiding inexperienced surgeons in their choice of the skin wound closure method.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 6","pages":"386-393"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10699892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Polyendocrine syndromes in dogs].","authors":"Sina Strey, Reinhard Mischke, Johanna Rieder","doi":"10.1055/a-2183-0654","DOIUrl":"10.1055/a-2183-0654","url":null,"abstract":"<p><p>The autoimmune polyendocrine syndrome (APS) refers to a combination of autoimmune endocrine disorders. It is rarely described in dogs. The most common combinations are hypoadrenocorticism and hypothyroidism, followed by diabetes mellitus, and less often hypoparathyroidism and orchitis. The diagnosis of the APS is based on the diagnosis of each endocrinopathy, as is the therapy, which involves the substitution of deficient hormones. If a patient was previously stable under treatment and is showing further signs (e.g. polyuria, polydipsia, or weight loss), the development of additional endocrinopathies like hypoadrenocorticism or diabetes mellitus should be considered. The diagnosis of the initially diagnosed endocrinopathy should also be critically questioned. This article summarizes some cases of our own animal hospital and selected cases published in the available literature.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"313-325"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Nasal obstruction: Odontogenic cysts in 4 brachycephalic dogs].","authors":"Sarah Rösch, Jan Schreyer, Gerhard Oechtering","doi":"10.1055/a-2157-1370","DOIUrl":"10.1055/a-2157-1370","url":null,"abstract":"<p><strong>Objective: </strong>Odontogenic cysts may be of developmental or inflammatory origin. They are frequently observed in brachycephalic dogs. Due to their expansive growth, cysts in the maxilla may extend into the nasal cavity, obstruct the nasal airway and cause nasal discharge. Epithelial cysts may lead to a comparable clinical picture. A new endonasal endoscopic intervention for the removal of these cysts is described.</p><p><strong>Material and methods: </strong>Four brachycephalic dogs (Boxer, Chihuahua, French bulldog, Pug) with unilateral cysts obstructing the nasal cavity were included in the study. The animals underwent clinical examination, computed tomography (CT) imaging and rhinoscopy examination. Histopathologic evaluation of the cyst wall was performed. In addition to dental surgery and conventional extraction of the involved tooth, the cyst wall was removed by endoscopic intervention via the physiologic nasal opening. Clinical course following treatment was assessed by rhinoscopy and CT.</p><p><strong>Results: </strong>The main clinical signs were unilateral or bilateral serous to hemorrhagic nasal discharge. Nasal airflow was restricted in all patients. Removal of the cysts and involved teeth did not lead to any intra- and postoperative complications. No recurrence of the cysts was observed. Histologic diagnosis consisted of an epidermoid cyst, a follicular cyst, a radicular cyst, and a canine odontogenic parakeratinized cyst (COPC). Neoplastic transformation was excluded in all cases.</p><p><strong>Conclusions: </strong>Removal of the cyst wall may be performed by means of minimally invasive endoscopic intervention via the physiologic nasal entrance. The procedure is curative and carries the risk of only few complications. In cases in which treatment is restricted to extraction of the affected tooth, the nasal airway may remain obstructed due to a calcified cyst wall.</p><p><strong>Clinical relevance: </strong>In brachycephalic dogs, oronasal defects due to dental pathology are the most common reason for chronic nasal discharge, whereas in normocephalic dogs nasal neoplasia are. Odontogenic cysts carry importance as differential diagnosis of nasal discharge.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"301-312"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Inhalation anesthesia in the cat: Development of cuff pressure when using nitrous oxide].","authors":"Franziska Benesch, Frauke Paul, Michaele Alef","doi":"10.1055/a-2159-6016","DOIUrl":"10.1055/a-2159-6016","url":null,"abstract":"<p><strong>Objective: </strong>During inhalation anesthesia with nitrous oxide in oxygen the pressure in the cuff of the endotracheal tube may increase due to diffusion of nitrous oxide into the cuff. The aim of the study was to investigate the development of cuff pressure during nitrous oxide anesthesia under clinical conditions in feline patients and to identify possible influencing factors such as tube size and gas flow rate.</p><p><strong>Material and methods: </strong>The prospective study included cats scheduled for inhalation anesthesia with nitrous oxide for a minimum duration of 60 minutes at the Department for Small Animals of the University of Leipzig. Cuff pressure was adjusted with a cuff manometer and its development was recorded.</p><p><strong>Results: </strong>In total, the cuff pressure values of 24 cats were recorded. Animals were allocated into groups by tube size (ID 4.0 mm and ID 4.5 mm) and by fresh gas flow rate: low flow rate (0.6 l/min) and high flow rate (3 l/min). During anesthesia, cuff pressure increased over time, with statistical significance occurring from 45 minutes onwards in comparison to the initial cuff pressure (p=0.005). After 60 minutes, there was a mean cuff pressure increase of 3 cmH<sub>2</sub>O. Despite this moderate mean increase, highly variable pressure values up to 48 cmH<sub>2</sub>O in individual animals were recorded. No cat reached the termination criterion of 60 cmH<sub>2</sub>O cuff pressure. Effects of tube size (p=0.63) and flow rate (p=0.334) on the cuff pressure were not evident.</p><p><strong>Conclusion: </strong>After a period of 45 minutes of nitrous oxide administration, a significant increase in cuff pressure occurs in the cat. However, tube size and total gas flow rate do not seem to influence the cuff pressure development.</p><p><strong>Clinical relevance: </strong>When using nitrous oxide during inhalation anesthesia, regular cuff pressure evaluation and correction are necessary and hence recommended in feline patients. As individual pressure changes may be highly variable, no fixed recommendations for optimal management are possible.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"326-335"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Urinalysis in dogs and cats, part 2: Urine sediment analysis].","authors":"Sandra Seigner, Karin Weber, Roswitha Dorsch","doi":"10.1055/a-2122-5324","DOIUrl":"10.1055/a-2122-5324","url":null,"abstract":"<p><p>Examination of the urine sediment is part of a routine urinalysis and is undertaken in order to identify insoluble particles in the urine. This procedure is mainly used in the context of diagnostic evaluation of urinary tract diseases, but may also be useful for the diagnosis of systemic diseases and intoxications. Analysis of fresh urine is recommended as changes in cell morphology, cell lysis and in vitro crystal formation may occur in the course of its storage. Manual urine sediment analysis is still performed in many veterinary practices. Native wet-mount preparations are suitable for the identification and quantification of urine sediment particles. The examination of stained wet-mount preparations or air-dried smears may be necessary to further differentiate cells and to identify bacteria. For several years, automatic urine sediment analyzers have been available in veterinary medicine. These save considerable time and staff resources, however verification of the automatically generated results by an experienced observer remains necessary. Urine sediment particles that are frequently identified and clinically relevant include red blood cells, white blood cells, different types of epithelial cells, crystals, and casts as well as bacteria. Furthermore, parasite eggs, fungal hyphae, lipid droplets, spermatozoa, fibres, hair, mucus, plant parts or environmental contaminations may be found in the urine sediment and result in a complication of the result interpretation.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"336-350"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jana Müller, Anna Erokhina, Isabell Gletscher, Frank Mittenzwei, Janina Müller, Lisa Schikowski, Pia Cigler, Manfred Henrich
{"title":"Metastasizing squamous cell carcinoma in a 50-year-old Eastern Hermann's tortoise (Testudo hermannii boettgeri).","authors":"Jana Müller, Anna Erokhina, Isabell Gletscher, Frank Mittenzwei, Janina Müller, Lisa Schikowski, Pia Cigler, Manfred Henrich","doi":"10.1055/a-2180-5893","DOIUrl":"10.1055/a-2180-5893","url":null,"abstract":"<p><p>A 50-year-old female Hermann's tortoise (<i>Testudo hermannii boettgeri</i>) was presented with anorexia and lethargy. Clinical examination revealed multiple, visually inconspicuous but indentable areas in the shell corresponding to osteolysis radiographically. Soft tissue nodules and osteolytic lesions were also noted in the limbs. Laboratory results revealed elevated aspartate aminotransferase activity and uric acid concentrations, hypoglycemia, and hyperphosphatemia. <i>Klebsiella oxytoca</i> was isolated from a biopsied scutal area, and the biopsy suggested neoplasia. After a short period of clinical improvement, the animal's condition deteriorated, and it died. Post mortem computed tomography revealed polyostotic lytic lesions of multiple bones and the shell with associated soft tissue nodules protruding into the coelom, and nodular lung lesions. Necropsy, histopathology, and immunohistochemistry secured a diagnosis of a poorly differentiated, pan-cytokeratin-positive squamous cell carcinoma with widespread soft tissue and bone metastases, osteolysis and desmoplasia.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"368-374"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mitteilungen der DVG","authors":"","doi":"10.1055/a-2172-5967","DOIUrl":"https://doi.org/10.1055/a-2172-5967","url":null,"abstract":"Vom 7. bis 9. September fand die 5. Jahrestagung der DVG-Fachgruppe „Zier-, Zoo- und Wildvögel, Reptilien, Amphibien und Fische (ZZWRAF)“ in Gießen statt. Tagungsort war der Hörsaal des Medizinischen Lehrzentrums in der „Alten Chirurgie“ auf dem Gelände des Fachbereichs Humanmedizin. Fachgruppenleiter Prof. Dr. Michael Pees (Hannover) und Prof. Dr. Michael Lierz (Gießen) vom Organisationsteam vor Ort begrüßten die etwa 130 Teilnehmenden. Und auch DVG-Präsident Prof. Martin Kramer sprach Grußworte.","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136247076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Krentz, Michèle Bergmann, Sandra Felten, Katrin Hartmann
{"title":"[Options for treatment of feline infectious peritonitis - previously and today].","authors":"Daniela Krentz, Michèle Bergmann, Sandra Felten, Katrin Hartmann","doi":"10.1055/a-2147-3999","DOIUrl":"10.1055/a-2147-3999","url":null,"abstract":"<p><p>Feline infectious peritonitis (FIP) is one of the most common infectious diseases in cats that is fatal when untreated. So far, there is no legally available effective treatment in Germany. Treatment options include only symptomatic treatment (e. g. glucocorticoids, propentofylline), immunomodulatory approaches (e. g. interferons, polyprenyl immunostimulant), and antiviral chemotherapy with protease inhibitors (e. g. GC376) or nucleoside analogues (e. g. GS-441524, remdesivir). Symptomatic treatment does not cure FIP but may lead to a short-term improvement of clinical signs in a subset of cats. Immunomodulatory treatment has also not shown to be very promising. In contrary, the antiviral compounds GS-441524 and GC376 exhibited significant efficacy in several studies and their use saved the lives of many cats suffering from FIP. However, both agents are currently not licensed and thus cannot be legally administered by veterinarians in Germany. Legally, cats may only be legally treated with GS-441524 in a few countries (e.g. Great Britain and Australia). In other countries, GS-441524 is imported by cat owners via the black market and administered on their own. This article provides an overview of the available treatment options and an outlook on the legal use of effective antiviral drugs.</p>","PeriodicalId":49434,"journal":{"name":"Tieraerztliche Praxis Ausgabe Kleintiere Heimtiere","volume":"51 5","pages":"351-360."},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}