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Human immunodeficiency virus and Helicobacter pylori coinfection: Immune modulation and eradication failure. 人类免疫缺陷病毒和幽门螺杆菌共感染：免疫调节和根除失败。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-05-09 DOI: 10.1177/00494755251339521
Haidi Karam-Allah Ramadan, Zeinab N Ahmed, Abdel-Rahman AboDief, Zeinab R Mohamed, Hager M Hamed, Taha H El-Sherif
{"title":"Human immunodeficiency virus and <i>Helicobacter pylori</i> coinfection: Immune modulation and eradication failure.","authors":"Haidi Karam-Allah Ramadan, Zeinab N Ahmed, Abdel-Rahman AboDief, Zeinab R Mohamed, Hager M Hamed, Taha H El-Sherif","doi":"10.1177/00494755251339521","DOIUrl":"10.1177/00494755251339521","url":null,"abstract":"<p><p>The relationship between Human Immunodeficiency Virus (HIV) and <i>Helicobacter pylori</i> (H. pylori) is bidirectional and complex. <i>Helicobacter pylori,</i> by inducing local gastric and systemic immune responses, counteracts HIV invasion to CD4+ cells and other inflammatory cells and can reactivate HIV in latently infected immune cells. Human Immunodeficiency Virus infection, by reducing secretion of pro-inflammatory cytokines, reduces the incidence of H. pylori-induced gastric pathology. Gastric lymphoma regressed in some cases of people living with HIV (PLWH) after H. pylori eradication. Triple therapy for H. pylori could be associated with a strong immune. Treatment for both H. pylori and HIV can reduce the activation of either organism. However, the primary resistance to antibiotics such as levofloxacin, clarithromycin and metronidazole is higher among PLWH. This review highlights the need for further research and guidelines on the appropriate antibiotics in HIV-H. pylori co-infection particularly in PLWH who receive multiple antibiotic prophylaxis.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251339521"},"PeriodicalIF":0.5,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary spontaneous colporrhexis in a primigravida. 原发性自发性阴道破裂。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-05-06 DOI: 10.1177/00494755251338597
Eunice Susanna Abraham, Ashwin Sukumar, Arpit Jacob Mathew, Amy Eapen Mathew, Immanuel Judson Paul, Anne George Cherian
{"title":"Primary spontaneous colporrhexis in a primigravida.","authors":"Eunice Susanna Abraham, Ashwin Sukumar, Arpit Jacob Mathew, Amy Eapen Mathew, Immanuel Judson Paul, Anne George Cherian","doi":"10.1177/00494755251338597","DOIUrl":"https://doi.org/10.1177/00494755251338597","url":null,"abstract":"<p><p>Primary spontaneous colporrhexis is a rare condition but is an important differential of haemodynamic instability after an uneventful golden hour postnatally. We report such a case in a primipara who had presented in active labour. She had progressed well and delivered by normal vaginal delivery. About 5 h thereafter, she developed tachycardia and hypotension. The vaginal examination was suggestive of colporrhexis. At emergency laparotomy, a posterior uterine rent was identified and repaired. Timely identification is crucial and transfer where a laparotomy can be immediately performed may be life-saving.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251338597"},"PeriodicalIF":0.5,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simple nephrectomy for Xanthogranulomatous pyelonephritis - Is it really simple? 单纯肾切除术治疗黄色肉芽肿性肾盂肾炎-真的简单吗？
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-24 DOI: 10.1177/00494755251336500
Mohammad Shazib Faridi, Kartik Sridhar, Devesh Bhatia
{"title":"Simple nephrectomy for Xanthogranulomatous pyelonephritis - Is it really simple?","authors":"Mohammad Shazib Faridi, Kartik Sridhar, Devesh Bhatia","doi":"10.1177/00494755251336500","DOIUrl":"https://doi.org/10.1177/00494755251336500","url":null,"abstract":"<p><p>We present a retrospective review of histopathologically confirmed cases of Xanthogranulomatous pyelonephritis (XGP), which is a rare condition associated with high morbidity and mortality. Simple nephrectomy, though technically not simple, remains the definitive treatment. It is essential pre-operatively to diagnose or have a high index of suspicion of XGP to ensure the best outcome for these patients.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251336500"},"PeriodicalIF":0.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angola's cholera crisis and the struggle for effective outbreak control amid vaccine shortfalls. 安哥拉的霍乱危机以及在疫苗短缺的情况下为有效控制疫情而进行的斗争。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-24 DOI: 10.1177/00494755251337254
Abdulrakib Abdulrahim, Valdemiro Amilton Rafael, Bashar Haruna Gulumbe
{"title":"Angola's cholera crisis and the struggle for effective outbreak control amid vaccine shortfalls.","authors":"Abdulrakib Abdulrahim, Valdemiro Amilton Rafael, Bashar Haruna Gulumbe","doi":"10.1177/00494755251337254","DOIUrl":"https://doi.org/10.1177/00494755251337254","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251337254"},"PeriodicalIF":0.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emphysematous pyelonephritis due to mucormycosis. 毛霉病所致的肺气肿性肾盂肾炎。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-17 DOI: 10.1177/00494755251332993
Spoorthi Sriram, Venu Shakthivel, Rangineni Jayaprada, Madala Chandana Sree, Kandula Venkata Koti Reddy, Rapur Ram
{"title":"Emphysematous pyelonephritis due to mucormycosis.","authors":"Spoorthi Sriram, Venu Shakthivel, Rangineni Jayaprada, Madala Chandana Sree, Kandula Venkata Koti Reddy, Rapur Ram","doi":"10.1177/00494755251332993","DOIUrl":"https://doi.org/10.1177/00494755251332993","url":null,"abstract":"<p><p>Emphysematous pyelonephritis is an acute necrotizing parenchymal and peri-renal infection caused by gas-forming uropathogens. We present such a diagnosis in a non-diabetic patient with a rare causative agent.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251332993"},"PeriodicalIF":0.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approach to pyrexia of unknown origin in low- and middle-income countries. 低收入和中等收入国家不明原因发热的处理方法。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-13 DOI: 10.1177/00494755251333964
Ashok Kumar Pannu
{"title":"Approach to pyrexia of unknown origin in low- and middle-income countries.","authors":"Ashok Kumar Pannu","doi":"10.1177/00494755251333964","DOIUrl":"https://doi.org/10.1177/00494755251333964","url":null,"abstract":"<p><p>Pyrexia of unknown origin (PUO) remains a significant diagnostic challenge in low- and middle-income countries (LMICs), where infections predominate despite an increasing burden of non-infectious inflammatory diseases and malignancy. Extrapulmonary tuberculosis, lymphoma, and Still's disease are among the leading causes. This article reviews the evolving epidemiology of PUO in LMICs and proposes a structured, stepwise diagnostic approach that integrates local epidemiology, potential diagnostic clues, targeted investigations, and whole-body imaging to improve diagnostic accuracy while minimising unnecessary testing.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251333964"},"PeriodicalIF":0.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vermamoeba vermiformis causing primary amoebic meningoencephalitis - A diagnostic challenge. 蠕形虫引起原发性阿米巴脑膜脑炎-一个诊断挑战。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-03-17 DOI: 10.1177/00494755251327531
Geethalakshmi Velayudhan, Maridas Tom Thomas, Suseela Kundoly V, Thomas Joseph, Adarsh Aayiliath K
{"title":"<i>Vermamoeba vermiformis</i> causing primary amoebic meningoencephalitis - A diagnostic challenge.","authors":"Geethalakshmi Velayudhan, Maridas Tom Thomas, Suseela Kundoly V, Thomas Joseph, Adarsh Aayiliath K","doi":"10.1177/00494755251327531","DOIUrl":"10.1177/00494755251327531","url":null,"abstract":"<p><p>Amoebic meningo-encephalitis is difficult to diagnose because the clinical signs of the disease mimic bacterial meningitis, compared to which it progresses rapidly towards a fatal outcome. Diagnosis is possible by cerebro-spinal fluid (CSF) wet mount examination. Two confirmed cases of amoebic meningoencephalitis from Kerala state India are presented.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"128-130"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycerine soaked bandage drain: A novel technique for non-surgical management of neonatal rectal prolapse. 甘油浸泡绷带引流：一种非手术治疗新生儿直肠脱垂的新技术。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-03-28 DOI: 10.1177/00494755251320248
Survesh K Gupta, Rafey A Rahman, Muniba Alim, Umesh K Gupta
{"title":"Glycerine soaked bandage drain: A novel technique for non-surgical management of neonatal rectal prolapse.","authors":"Survesh K Gupta, Rafey A Rahman, Muniba Alim, Umesh K Gupta","doi":"10.1177/00494755251320248","DOIUrl":"10.1177/00494755251320248","url":null,"abstract":"<p><p>Neonatal rectal prolapse (NRP) is a rare, distressing condition in neonates, often linked to malnutrition, diarrhoea, and constipation. The effectiveness of glycerine soaked bandage drain for non-surgical management of idiopathic NRP is demonstrated.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"108-112"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystoisospora belli infection in a person with diabetes mellitus and chronic kidney disease. 一名糖尿病和慢性肾病患者感染贝氏囊孢子虫[AM1]。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2024-11-25 DOI: 10.1177/00494755241301495
Madhusree Sett, Manharpreet Kaur, Suresh Selvam, Sanjay Jain, Abhishek Mewara, Rakesh Sehgal
{"title":"<i>Cystoisospora belli</i> infection in a person with diabetes mellitus and chronic kidney disease.","authors":"Madhusree Sett, Manharpreet Kaur, Suresh Selvam, Sanjay Jain, Abhishek Mewara, Rakesh Sehgal","doi":"10.1177/00494755241301495","DOIUrl":"10.1177/00494755241301495","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"169-171"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the predictive superiority of Garg's classification for surgical decision-making in perianal fistula management. 评价Garg分类在肛瘘治疗手术决策中的预测优势。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-04-21 DOI: 10.1177/00494755251331323
Naresh Lodhi, Dileep Thakur, Amrendra Verma, Uday Somashekar, Deepti Bala Sharma, Dhananjaya Sharma
{"title":"Evaluating the predictive superiority of Garg's classification for surgical decision-making in perianal fistula management.","authors":"Naresh Lodhi, Dileep Thakur, Amrendra Verma, Uday Somashekar, Deepti Bala Sharma, Dhananjaya Sharma","doi":"10.1177/00494755251331323","DOIUrl":"https://doi.org/10.1177/00494755251331323","url":null,"abstract":"<p><p><b>Background:</b> Managing perianal fistulae involves balancing the risks of incontinence and recurrence, with existing classification systems offering limited guidance for surgical decision-making. Garg's classification provides a detailed assessment of fistula anatomy, aiding the choice between fistulotomy and sphincter-sparing procedures. This study evaluates its predictive accuracy.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":"55 2","pages":"124-127"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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