Ultraschall in Der Medizin最新文献

{"title":"Perfusion-based malignancy assessment of soft-tissue tumors by contrast-enhanced ultrasound (CEUS): a comprehensive analysis of 187 cases.","authors":"Paul Mick, Katharina Sehmsdorf, Burkhard Lehner, Andreas Geisbüsch, Tobias Renkawitz, Mustafa Hariri, Julian Doll, Stefanos Tsitlakidis","doi":"10.1055/a-2549-6101","DOIUrl":"10.1055/a-2549-6101","url":null,"abstract":"<p><p>This study aimed to examine the perfusion characteristics of benign and malignant soft-tissue tumors (STT) using contrast-enhanced ultrasound (CEUS) and to correlate STT micro-perfusion with malignancy. Findings were compared with patient characteristics, clinical presentations, MRI findings, and histopathological outcomes.This prospective single-center study involved patients with unclear STTs who were scheduled for STT biopsy. Clinical assessments and preoperative MRI were conducted along with CEUS. Perfusion quantification was performed, and perfusion parameters (peak enhancement [PE], rise time, wash-in perfusion index, and washout rate) were calculated. Perfusion characteristics of different STTs were compared.187 patients were included in the final analysis. Significant differences in CEUS perfusion between benign and non-benign STTs were demonstrated. Non-benign tumors showed significantly higher tumor perfusion and differences were also significant when comparing semi-malignant, malignant, and metastatic STTs. (PE-benign 107.74 [34.65-345.62]; PE-semi-malignant 166.06 [60.14-374.47]; PE-malignant 1042.24 [358.15-4917.74]; PE-metastasis 2632.37 [2249.46-3788.94]. ROC analysis demonstrated a sensitivity of 80% and a PPV of 69% for malignant tumor detection using a cut-off value for peak enhancement of 137 [a.u.].CEUS appears to be a promising tool for primary STT evaluation in addition to MRI. Furthermore, it can detect vital areas within the tumor tissue and could be utilized to increase biopsy accuracy.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"190-197"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transthoracic echocardiography - the new AWMF S2k guidelines establish uniform standards.","authors":"Jan Knierim","doi":"10.1055/a-2751-9217","DOIUrl":"10.1055/a-2751-9217","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"146-148"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transthoracic echocardiography Guidelines of the German Society for Ultrasound in Medicine, German Cardiac Society, German Society of Anesthesiology and Intensive Care Medicine, German Society of Internal Medicine, Professional Association of German Internists, and the German Association of Cardiologists in Private Practice (Association of Scientific Medical Societies in Germany, S2k LL85-004, 9/1/20.","authors":"Jan Knierim, Henrik Ten Freyhaus, Harry Magunia, Sebastian Kruck, Matthias Göpfert, Norbert Smetak, Constantin S von Kaisenberg, Caroline Morbach, Sebastian Ewen, Frank Flachskampf","doi":"10.1055/a-2775-3065","DOIUrl":"10.1055/a-2775-3065","url":null,"abstract":"<p><p>Echocardiography is the most commonly used imaging method for evaluating the heart. It plays a central role in the cardiology routine and in acute and emergency situations, and is an essential component of the medical decision-making process. In spite of its high clinical relevance, national recommendations standardizing the examination procedure, equipment settings, and image documentation have been lacking. The present guidelines were created by the German Society for Ultrasound in Medicine and the German Cardiac Society in coordination with the German Society of Anesthesiology and Intensive Care Medicine, German Society of Internal Medicine, Professional Association of German Internists, and the German Association of Cardiologists in Private Practice. The recommendations were formulated in consensus, published as draft guidelines, and finalized by the participating professional associations after evaluation of the feedback. The document meets the criteria for S2k guidelines in accordance with the Association of Scientific Medical Societies in Germany and defines binding standards for performing transthoracic echocardiography. The guidelines define which images and measurements are required to ensure valid and reproducible findings. The main recommendations relate to device settings, image acquisition, the minimum dataset to be acquired, and the definition of focused cardiac ultrasound (FoCUS). The complete long version of the guidelines is available on the website of the Association of Scientific Medical Societies in Germany. NOTE : The short version of this guideline is being published simultaneously in the journals Ultraschall in der Medizin - European Journal of Ultrasound and Die Kardiologie.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"149-159"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SonoGame - more than just a game: Evaluation of an ultrasound training platform.","authors":"Selin Guergan, Victoria Henze, Christian Gall, Birgitt Schönfisch, Sara Y Brucker, Sven Bertel, Lukas Mayer, Matthias Süncksen, Michael Teistler, Markus Hahn","doi":"10.1055/a-2627-8194","DOIUrl":"10.1055/a-2627-8194","url":null,"abstract":"<p><p>Ultrasound examination is a vital imaging tool in medicine, yet opportunities for comprehensive theoretical and practical training during medical education are limited. Effective ultrasound education requires both theoretical knowledge and hands-on practice. To address this, we developed SonoGame, a gamified platform designed to teach ultrasound skills to medical students. SonoGame provides a step-by-step introduction to ultrasound imaging and aims to improve skills such as image orientation, spatial visualization, and hand-eye-coordination through mini-games using geometric objects. This study evaluates the impact of SonoGame training on ultrasound skills.In this prospective, single-center study, 56 medical students, the majority of whom had no prior ultrasound experience, were randomly assigned to either a control group or a SonoGame group. The SonoGame group trained with the platform in four 30-minute sessions over 4 weeks, while the control group received no training. Ultrasound skills were assessed in both groups before and after the training period.The SonoGame group showed significant improvement in ultrasound skills, particularly with complex anatomical structures, compared to the control group. Participants in the SonoGame group also reported increased familiarity and confidence with sonography, viewing SonoGame as a valuable tool in their training.SonoGame is an effective supplement to conventional ultrasound education, enhancing the skills necessary for ultrasound examinations in medical students.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"171-179"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal Ultrasound for Assessment of Renal Fibrosis in Biopsy-Proven Patients with Chronic Kidney Disease.","authors":"Xinyue Huang, Tianhong Wei, Jie Li, Letian Xu, Yangshuo Tang, Jin-Tang Liao, Bo Zhang","doi":"10.1055/a-2559-7743","DOIUrl":"10.1055/a-2559-7743","url":null,"abstract":"<p><p>To establish a discriminant function model combining clinical data and multimodal ultrasound to predict the degree of renal fibrosis in patients with chronic kidney disease (CKD) and to explore the application value of the non-invasive assessment of renal fibrosis by new ultrasound techniques.Clinical data and ultrasonography, shear wave elastography, and angio planewave ultrasensitive imaging characteristics of patients with CKD were collected. The significant indicators were screened to establish discriminant function models to distinguish the degree of renal fibrosis, and the diagnostic efficacy was evaluated.The 158 patients were divided into 4 groups according to pathological results. The significant indicators among or within the 4 groups were mainly age, estimated glomerular filtration rate, serum creatinine, peak systolic velocity and resistance index of renal arteries, kidney elasticity, and arcuate artery vascular density (p<0.05). The discriminant function models exhibited good diagnostic efficiency and higher accuracy compared to any single indicator.The SWE elasticity value of the kidney increases with the degree of fibrosis, while AP can visualize microvascular conditions qualitatively and quantitatively. Multimodal ultrasound combined with clinical data is a non-invasive strategy for the assessment of renal fibrosis.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"180-189"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gaming as an Educational Tool in Learning Ultrasound.","authors":"Alina Popescu, Tudor Moga, Roxana Șirli","doi":"10.1055/a-2785-0626","DOIUrl":"https://doi.org/10.1055/a-2785-0626","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"47 2","pages":"118-121"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of image quality in five different handheld ultrasound devices and analysis of various impact factors.","authors":"Antje Naas, Julian Kober, Tönnis Trittler, Richard Nauber, Edgar Manfred Gustav Dorausch, Nicole Kampfrath, Franz Brinkmann, Maia Arsova, Julia Husman, Robert Langanke, Stefan Sulk, Katja Matthes, Tina Gabriel, Andreas Teufel, Patrick Behrendt, Antoaneta Markova, Martin Franck, Christian Jenssen, Daniel Merkel, Valentin Blank, Thomas Karlas, Marcus Seeger, Marius Andreas Eckart, Lukas Poralla, Malte Lehmann, Jonas Staudacher, Matthias Ziesch, Julia Aland, Lueder Herzog, Angelika Herzog, Christian Jürgensen, Gerhard Paul Fettweis, Jochen Hampe, Moritz Herzog","doi":"10.1055/a-2809-7627","DOIUrl":"10.1055/a-2809-7627","url":null,"abstract":"<p><p>Handheld ultrasound (HHUS) devices are increasingly used in clinical practice due to their portability and cost-effectiveness. However, HHUS image quality remains variable, and a standardized expert-based evaluation protocol is lacking. This study compares the image quality of B-mode recordings of five HHUS models with a high-end reference system (HEUS) using a blinded assessment to identify differences, covariates, offering a standardized evaluation framework.In this blinded, multi-center study, video sequences of the liver, pancreas, and sigmoid colon were recorded in ten volunteers using 5 HHUS devices - Vscan Air, Butterfly iQ+, Philips Lumify, Clarius C3, and Clarius C3 HD3 - and one HEUS (GE Logiq E10). Twenty-two physicians with many years of abdominal ultrasound experience rated blinded clips for 5 image quality parameters.The HEUS consistently received the highest ratings. Image quality differed significantly between HHUS devices. Clarius systems showed the smallest deviation from the reference, followed by Vscan Air and Philips Lumify. All image parameters significantly correlated with the overall impression, without a single dominant factor. The patients' BMI had no relevant influence. Examiner experience was less impactful than device familiarity and personal preference.The image quality of HEUS remained superior to all tested HHUS devices. Further subdivision of image quality aspects did not provide additional information. Furthermore, we could not identify significant covariates in our setup. These findings could justify simplified setups with reduced questionnaires and requirements for examiners.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146198008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-Microangiography for Evaluating Crohn's Disease Activity in Pediatric Patients: A Prospective Study.","authors":"Ying Wang, Haixia Feng, Li Wei, Rui Cheng, Yunlin Huang, Shiwen Wang, Yueyang Guan, Ying Wang, Kassa Darge, Yi Dong, Wei Cai","doi":"10.1055/a-2771-2690","DOIUrl":"10.1055/a-2771-2690","url":null,"abstract":"<p><p>To investigate the role of ultra-microangiography (UMA) in evaluating Crohn's disease (CD) activity in pediatric patients.Pediatric patients diagnosed with CD were included in this prospective study. A Resona A20 ultrasound machine (Mindray Medical Systems, China) was used for all patients. The semiquantitative scores of color Doppler flow imaging (CDFI) and UMA on the thickest segments of bowel walls were assessed according to the Limberg score. The Pediatric Crohn's Disease Activity Index (PCDAI) was the reference standard to evaluate CD activity. ROC analysis was performed to compare the diagnostic efficiency of Limberg scores between CDFI and UMA.Sixty pediatric CD patients were included and divided into three groups according to PCDAI: Group 1, inactive CD (n = 37); Group 2, mild CD (n = 13); and Group 3, moderate to severe CD (n = 10). By UMA, significant differences in Limberg scores were found between Groups 1 and 3 (P < 0.001), Groups 2 and 3 (P = 0.044), and Groups 1 and 2 (P = 0.029). The combined AUROC of B-mode ultrasound (BMUS) features and UMA features in pediatric CD activity evaluation was 0.934, with sensitivity of 87.0% and specificity of 94.6%, which was significantly higher than that of the combined BMUS features and CDFI (P = 0.048).By sensitively depicting the low velocity blood flow signals and displaying microvascular morphologies of the bowel wall, UMA is an effective noninvasive imaging method enabling semiquantitative evaluation of the activity of CD in pediatric patients.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and outcomes of prenatally unexplained fetal anemia.","authors":"Saja Anabusi, Charles Litwin, Greg Ryan, David Chitayat, Shiri Shinar","doi":"10.1055/a-2773-2240","DOIUrl":"10.1055/a-2773-2240","url":null,"abstract":"<p><p>Despite advances in diagnostic approaches, fetal anemia of unknown etiology continues to be observed in rare cases. This study aimed to assess the incidence of unexplained fetal anemia and to evaluate the associated perinatal outcomes.We conducted an observational retrospective cohort study of all fetuses that underwent fetal blood sampling (FBS) due to an MCA-PSV>1.5 MoM at a tertiary center between 2007 and 2024. Fetuses were included if they had moderate or severe anemia defined as a hemoglobin (Hgb) deviation of more than 20g/L below a gestational age adjusted mean, with a negative anemia workup. Prenatal and postnatal outcomes were obtained.Among 376 fetuses that underwent fetal blood sampling for anemia, 361 (96%) had an identified cause, while 15 (4%) had moderate to severe anemia of unknown etiology. Seven fetuses presented with non-immune hydrops and eight with other major structural anomalies not typically associated with anemia. Eleven (73%) of the 15 fetuses with unexplained anemia had thrombocytopenia, with platelets below 100000/µL in 8 cases and below 50000/µL in 6 cases. Seven cases (47%) resulted in perinatal death. Rare causes of anemia were elucidated in only 5 cases (33%) postnatally despite extensive investigations.Unexplained fetal anemia is uncommon and is associated with poor neonatal outcomes warranting close pre- and postnatal surveillance.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic pulsatile diameter changes in fetuses with growth restriction.","authors":"Markus Gonser, Ladina Vonzun, Nicole Ochsenbein-Kölble","doi":"10.1055/a-2782-7679","DOIUrl":"https://doi.org/10.1055/a-2782-7679","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}