Undersea and Hyperbaric Medicine最新文献

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Hyperbaric treatment deviations for U.S. Navy divers: Spinal DCS 美国海军潜水员的高压氧治疗偏差:脊柱DCS
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-08-10 DOI: 10.22462/613
John DeMis MD, Brian Keuski MD, April Due DO
{"title":"Hyperbaric treatment deviations for U.S. Navy divers: Spinal DCS","authors":"John DeMis MD, Brian Keuski MD, April Due DO","doi":"10.22462/613","DOIUrl":"https://doi.org/10.22462/613","url":null,"abstract":"Introduction The United States Navy (USN) developed and refined standardized oxygen treatment tables for diving injuries, but USN tables may not address all situations of spinal decompression sickness (DCS). We describe a detailed recompression treatment regimen that deviated from standard USN protocol for an active-duty USN diver with a severe, delayed presentation of spinal cord DCS. Case Report A USN diver surfaced from his second of three dives on a standard Navy ‘no-Decompression’ Air SCUBA dive (Max depth 101 fsw utilizing a Navy Dive Computer) and developed mid-thoracic back pain, intense nausea, paresthesias of bilateral feet, and penile erection. Either not recognizing the constellation of symptoms as DCS and after resolution of the aforementioned symptoms, he completed the third planned dive (essentially an in-water recompression). Several hours later, he developed paresthesias and numbness of bilateral feet and legs and bowel incontinence. He presented for hyperbaric treatment twenty hours after surfacing from the final dive and was diagnosed with severe spinal DCS. Based on the severity of clinical presentation and delay to treatment, the initial and follow-on treatments were modified from standard USN protocol. MRI of the spine four days after initial presentation demonstrated a 2∙2 cm lesion at the T4 vertebral level extending caudally. Follow-up examinations over two years demonstrated almost complete return of motor and sensory function; however, the patient continued to suffer fecal incontinence and demonstrated an abnormal post-void residual urinary volume. An atypical presenting symptom, a discussion of MRI findings, and clinical correlations to the syndrome of spinal DCS are discussed throughout treatment and long-term recovery of the patient.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"39 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87158015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Buoyant ascent rate profiles for the MK10 and MK11 submarine escape and immersion equipment MK10和MK11潜艇逃生和浸入设备的浮力上升率曲线
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-08-09 DOI: 10.22462/631
{"title":"Buoyant ascent rate profiles for the MK10 and MK11 submarine escape and immersion equipment","authors":"","doi":"10.22462/631","DOIUrl":"https://doi.org/10.22462/631","url":null,"abstract":"Introduction: Since the U.S. Navy transitioned from the MK10 to the MK11 submarine escape and immersion equipment (SEIE) there has been an increase in the incident rate of pulmonary barotrauma during submarine escape training. This study compares ascent rate profiles of the MK10 and MK11 SEIE to determine if ascent rate differences between the escape suits are associated with an increase in pulmonary barotraumas. Methods: Buoyant ascent rates of the MK10 and MK11 SEIE were compared using weighted manikins equivalent to the 1st, 50th, and 99th percentile body weight of a submariner. Human ascents using the MK11 (n=126) were compared to human ascents in the same trainer wearing the MK10 (n=124). Results: Manikin mean ascent times were faster for the MK10 compared to the MK11 (5.19 seconds vs 5.28 seconds, p < 0.05). Terminal velocity (Vt) was affected by manikin weight (p < 0.001). Human trials confirmed the manikin results. The average mean ascent velocity for the MK10 group was 0.155 meters/second faster than the MK11 group mean ascent velocity (p < 0.001). Mean ascent velocity was inversely correlated with all anthropometrics for the MK10 group (p < 0.01). Neither height nor body mass index showed a significant association with mean ascent velocity for the MK11 group. Conclusions: The Vt of buoyant ascents are significantly affected by body weight. As the mean ascent rate of the MK11 is slower than that of the MK10, ascent rate profile differences between the suits do not appear to explain the recent increase in pulmonary barotrauma incident rates during escape training.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86792682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric oxygen therapy for avascular necrosis of the femoral head: A case report 高压氧治疗股骨头缺血性坏死1例报告
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-07-13 DOI: 10.22462/644
Adam Pearl, MD, Steven Pearl, MD
{"title":"Hyperbaric oxygen therapy for avascular necrosis of the femoral head: A case report","authors":"Adam Pearl, MD, Steven Pearl, MD","doi":"10.22462/644","DOIUrl":"https://doi.org/10.22462/644","url":null,"abstract":"The hip is the most common location for avascular necrosis of the femoral head (AVN), with an estimated incidence in the United States of 10,000 to 20,000 new cases per year. The current standard of care for early disease is core decompression, with bone marrow injections becoming more commonplace. Hyperbaric oxygen enhances oxygen delivery to tissue, promotes an anti-inflammatory and pro-healing environment, and helps initiate angiogenesis. We believe that these properties of HBO2 make it a unique tool for AVN and applied it in conjunction with standard of care for our patient.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"22 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88178279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Buoyant ascent rate profiles for the MK10 and MK11 submarine escape and immersion equipment. MK10和MK11潜艇逃生和浸入设备的浮力上升率曲线。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
David M Fothergill, Christopher S Frederick, Linda M Hughes
{"title":"Buoyant ascent rate profiles for the MK10 and MK11 submarine escape and immersion equipment.","authors":"David M Fothergill, Christopher S Frederick, Linda M Hughes","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Since the U.S. Navy transitioned from the MK10 to the MK11 submarine escape and immersion equipment (SEIE), there has been an increase in the incident rate of pulmonary barotrauma during submarine escape training. This study compares the ascent rate profiles of the MK10 and MK11 SEIE to determine if ascent rate differences between the escape suits are associated with increased pulmonary barotraumas.</p><p><strong>Methods: </strong>Buoyant ascent rates of the MK10 and MK11 SEIE were compared using weighted manikins equivalent to the 1st, 50th, and 99th percentile body weight of a submariner. Human ascents using the MK11 (n=126) were compared to human ascents in the same trainer wearing the MK10 (n=124).</p><p><strong>Results: </strong>Manikin mean ascent times were faster for the MK10 than the MK11 (5.19 seconds vs 5.28 seconds, p ≺ 0.05). Terminal velocity (Vt) was affected by manikin weight (p ≺ 0.001). Human trials confirmed the manikin results. The average mean ascent velocity for the MK10 group was 0.155 meters/ second faster than the MK11 group's mean ascent velocity (p ≺ 0.001). Mean ascent velocity was inversely correlated with all anthropometrics for the MK10 group (p ≺ 0.01). Neither height nor body mass index showed a significant association with mean ascent velocity for the MK11 group.</p><p><strong>Conclusions: </strong>The Vt of buoyant ascents is significantly affected by body weight. As the mean ascent rate of the MK11 is slower than that of the MK10, ascent rate profile differences between the suits do not appear to explain the recent increase in pulmonary barotrauma incident rates during escape training.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"343-358"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric hydrogen therapy improves secondary brain injury after head trauma. 高压氢治疗可改善颅脑外伤后继发性脑损伤。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
Yohei Otsuka, Satoshi Tomura, Terushige Toyooka, Satoru Takeuchi, Arata Tomiyama, Tomoko Omura, Daizoh Saito, Kojiro Wada
{"title":"Hyperbaric hydrogen therapy improves secondary brain injury after head trauma.","authors":"Yohei Otsuka, Satoshi Tomura, Terushige Toyooka, Satoru Takeuchi, Arata Tomiyama, Tomoko Omura, Daizoh Saito, Kojiro Wada","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The pathophysiology of traumatic brain injury (TBI) is caused by the initial physical damage and by the subsequent biochemical damage (secondary brain injury). Oxidative stress is deeply involved in secondary brain injury, so molecular hydrogen therapy may be effective for TBI. Hydrogen gas shows the optimal effect at concentrations of 2% or higher, but can only be used up to 1.3% in the form of a gas cylinder mixed with oxygen gas, which may not be sufficiently effective. The partial pressure of hydrogen increases in proportion to the pressure, so hyperbaric hydrogen therapy (HBH2) is more effective than that at atmospheric pressure.</p><p><strong>Methods: </strong>A total of 120 mice were divided into three groups: TBI + non-treatment group (TBI group; n = 40), TBI + HBH2 group (n = 40), and non-TBI + non-treatment group (sham group; n = 40). The TBI and TBI + HBH2 groups were subjected to moderate cerebral contusion induced by controlled cortical impact. The TBI + HBH2 group received hyperbaric hydrogen therapy at 2 atmospheres for 90 minutes, at 30 minutes after TBI. Brain edema, neuronal cell loss in the injured hippocampus, neurological function, and cognitive function were evaluated.</p><p><strong>Results: </strong>The TBI + HBH2 group showed significantly less cerebral edema (p ≺ 0.05). Residual hippocampal neurons were significantly more numerous in the TBI + HBH2 group on day 28 (p ≺ 0.05). Neurological score and behavioral tests showed that the TBI + HBH2 group had significantly reduced hyperactivity on day 14 (p ≺ 0.01).</p><p><strong>Conclusion: </strong>Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"403-411"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bubble rupture & viability of red blood cells under resonant acoustic standing waves. 共振声驻波作用下红细胞的气泡破裂与活力。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
Edwin López Ramos, Manuel Rivera Bengoechea, Silvina Cancelos Mancini, Carlos Marín Martín
{"title":"Bubble rupture & viability of red blood cells under resonant acoustic standing waves.","authors":"Edwin López Ramos, Manuel Rivera Bengoechea, Silvina Cancelos Mancini, Carlos Marín Martín","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>The presentation of a novel prospective treatment for scenarios where bubble presence in the bloodstream poses a clinical risk. The method relies on generating resonant acoustic standing waves within a limb to non-invasively accelerate the dissolution of bubbles present in the bloodstream via bubble rupture. Additionally, a preliminary assessment of the effects of the resonant acoustic waves and bubble rupture events on red blood cell viability is provided.</p><p><strong>Methods: </strong>Two semicircular piezoelectric (PZT) transducers electrically connected to each other were assembled around a small-girth segment of a rear thigh removed from a swine specimen. When driven at the frequency of electric resonance, this swine thigh and PZT transducer arrangement generates resonant acoustic standing waves within the swine thigh. Consequently, mechanical resonance of the system was non-invasively established by monitoring the electric response of the PZT to the applied frequency. The resonant acoustic field generated was used for the detection and rupture of bubbles that travel through a simulated blood vessel installed across the swine thigh. Two sets of experiments were carried out using this methodology, one with the artificial blood vessel filled with saline solution and one with defibrinated sheep blood. For the latter case, a preliminary hematologic assessment was done with red blood cell counts.</p><p><strong>Conclusion: </strong>Resonant acoustic standing waves effectively rupture bubbles of 300μm to 900μm within a simplified swine thigh model. The average dissolved gas content was 44% due to resonant acoustic waves at powers above 20W. No significant effect on red blood cell counts was observed.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"373-381"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric oxygen therapy for treatment of COVID-19-related parosmia: a case report. 高压氧治疗新冠肺炎相关性鼻咽癌1例报告
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
Lior Krimus, Syed Hasan Rizvi, Anton Marinov, Hance Clarke, Rita Katznelson
{"title":"Hyperbaric oxygen therapy for treatment of COVID-19-related parosmia: a case report.","authors":"Lior Krimus, Syed Hasan Rizvi, Anton Marinov, Hance Clarke, Rita Katznelson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parosmia is a qualitative olfactory dysfunction characterized by distortion of odor perception. Traditional treatments for parosmia include olfactory training and steroids. Some patients infected with COVID-19 have developed chronic parosmia as a result of their infection. Here, we present the case of a patient who developed parosmia after a COVID-19 infection that was not improved by traditional treatments but found significant improvement after hyperbaric oxygen therapy[A1].</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"433-435"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric treatment deviations for U.S. Navy divers: Spinal DCS. 美国海军潜水员的高压氧治疗偏差:脊柱DCS。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
John DeMis, Brian Michael Keuski, April Due
{"title":"Hyperbaric treatment deviations for U.S. Navy divers: Spinal DCS.","authors":"John DeMis, Brian Michael Keuski, April Due","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The United States Navy (USN) developed and refined standardized oxygen treatment tables for diving injuries, but USN tables may not address all situations of spinal decompression sickness (DCS). We describe a detailed recompression treatment regimen that deviated from standard USN protocol for an active-duty USN diver with a severe, delayed presentation of spinal cord DCS.</p><p><strong>Case report: </strong>A USN diver surfaced from his second of three dives on a standard Navy 'no-Decompression' Air SCUBA dive (Max depth 101 fsw utilizing a Navy Dive Computer) and developed mid-thoracic back pain, intense nausea, paresthesias of bilateral feet, and penile erection. Either not recognizing the con- stellation of symptoms as DCS and after resolution of the aforementioned symptoms, he completed the third planned dive (essentially an in-water recompression). Several hours later, he developed paresthesias and numbness of bilateral feet and legs and bowel incontinence. He presented for hyperbaric treatment twenty hours after surfacing from the final dive and was diagnosed with severe spinal DCS. Based on the severity of clinical presentation and delay to treatment, the initial and follow-on treatments were modified from standard USN protocol. MRI of the spine four days after initial presentation demonstrated a 2.2 cm lesion at the T4 vertebral level extending caudally. Follow-up examinations over two years demonstrated almost complete return of motor and sensory function; however, the patient continued to suffer fecal incontinence and demonstrated an abnormal post-void residual urinary volume. An atypical presenting symptom, a discussion of MRI findings, and clinical correlations to the syndrome of spinal DCS are discussed throughout treatment and long-term recovery of the patient.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"383-390"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Memory surfacing among veterans with PTSD receiving hyperbaric oxygen therapy. 接受高压氧治疗的创伤后应激障碍退伍军人的记忆浮现。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
Keren Doenyas-Barak, Ilan Kutz, Erez Lang, Gabriela Levi, Shai Efrati
{"title":"Memory surfacing among veterans with PTSD receiving hyperbaric oxygen therapy.","authors":"Keren Doenyas-Barak, Ilan Kutz, Erez Lang, Gabriela Levi, Shai Efrati","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Growing evidence demonstrates that hyperbaric oxygen therapy (HBO2) induces neuroplasticity and can benefit individuals with post-traumatic stress disorder (PTSD). The aim of the current study was to evaluate the rate and pattern of memory surfacing during the course of HBO2 among veterans with combat-related PTSD.</p><p><strong>Methods: </strong>In a post-hoc analysis of a prospective study of the effect of HBO2 on PTSD symptoms in veterans, we evaluated the rate and character of memory surfacing during the course of HBO2 treatment. The treatment consisted of 60 daily 90-minute sessions, at 2 atmospheres absolute (ATA) pressure and 100% oxygen.</p><p><strong>Results: </strong>For 10 (35.7%) of the 28 participants, surfacing of new memories was reported during the HBO2 treatment course. Memories surfaced mainly during the second month of the treatment, at the mean session of 30.5±13.2. For 9 of these 10 participants, prodromal symptoms such as distress, anxiety, or worsening depression were documented; and in four, somatic pain was reported prior to memory surfacing. The pain and distress of memory surfacing resolved over the course of one to 10 days.</p><p><strong>Discussion: </strong>Among individuals with PTSD, the surfacing of new memories, accompanied by emotional distress and somatic pain, is common during HBO2. The surfacing of memories sheds light on the biological effect of HBO2 on the brain sequela of PTSD. It is highly important that in treating patients for any indication, HBO2 medical teams be aware and capable of addressing memory surfacing, particularly in those with a history of trauma.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"395-401"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altitude Diving on a Closed Circuit Oxygen Rebreather. 用闭路换气器进行高空潜水。
IF 0.9 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2023-04-01
Jonathan Conard
{"title":"Altitude Diving on a Closed Circuit Oxygen Rebreather.","authors":"Jonathan Conard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Closed-circuit rebreather diving is becoming more common. Rebreathers are complicated, adding to the stress of diving. Also adding to this complexity in the presented case is diving at a high-altitude, cold-water reservoir in Colorado. One diver experienced an oxygen-induced seizure at depth. The other diver had a rapid ascent with loss of consciousness. In this case, two experienced divers recovered from a possible devastating dive. Fortunately, they both returned to their pre-dive baseline health. Dive plan- ning is important, but as in this case, dive execution is paramount. This is a clinical case for an uncommon event presenting to an emergency department.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"50 4","pages":"391-393"},"PeriodicalIF":0.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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