{"title":"Dive Injury and Jellyfish Sting Case Study.","authors":"Michael J Day","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Wildlife exposure is a risk that trained divers are fully aware of. Examples of hazardous wildlife that divers may encounter include, but are not limited to, sharks, coral, sponges, eels, and jellyfish. Encountering wildlife can lead to a diver panicking or being forced to surface rapidly or in an uncontrolled manner due to panic or avoidance of the hazard. This may increase the risk of decompression illness (DCI), mainly pulmonary overinflation syndrome (POIS). Injuries caused by hazardous aquatic wildlife can also be distracting, leading dive supervisors and/or medical personnel to overlook unrelated injuries, such as DCI. If this occurs, the affected diver may suffer a grave outcome that could otherwise have been prevented.</p><p><strong>Case report: </strong>A 23-year-old Army Engineer diver developed sharp chest pain shortly after a 70-foot SCUBA dive complicated by suspected Portuguese man-of-war envenomation. He had painful tentacle contact on both hands/arms and neck, treated immediately with oxygen, vinegar, and seawater irrigation. In the ED, he was stable with normal oxygenation, ECG, labs, venous blood gas, and troponin. His chest pain resolved within 90 minutes, and skin findings improved with topical steroids and antihistamine therapy. He was diagnosed with jellyfish envenomation and atypical chest pain rather than a diving-related injury. At one-month follow-up, he was asymptomatic with normal chest radiographs and was cleared to return to diving.</p><p><strong>Discussion: </strong>It is of the utmost importance to be aware of all possible injuries or maladies that could have occurred to a diver, and for medical personnel to avoid becoming hyper-focused on a single injury, such as wildlife exposure or trauma.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"337-342"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margot Samson, Thomas Masters, Eduardo Fastag-Guttman, Christopher Logue, Daniel Popa
{"title":"Cardiac and Thrombotic Effects of Severe Carbon Monoxide Poisoning: A Case Series.","authors":"Margot Samson, Thomas Masters, Eduardo Fastag-Guttman, Christopher Logue, Daniel Popa","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Carbon monoxide (CO) poisoning is the most common source of poisoning in the United States. Acute poisoning can cause a wide range of symptoms. CO poisoning can have long-term morbidity as well, the most well-described of which is the development of delayed neurologic sequelae. CO can cause acute and chronic cardiovascular and thrombotic effects as well.</p><p><strong>Case report: </strong>We describe four cases of severe CO poisoning with distinct cardiac and thrombotic effects. Carboxyhemoglobin levels ranged from 23.1%-42.5%. All four were critically ill and intubated. All four were evaluated with transthoracic echocardiography (TTE), electrocardiogram, and laboratory evaluation. Three of the four patients developed decreased ejection fraction, and two had new wall-motion abnormalities noted on TTE. One underwent cardiac catheterization. Two of the patients developed thrombi. All four cases were quickly and aggressively treated with a course of hyperbaric oxygen.</p><p><strong>Discussion: </strong>Carbon monoxide (CO) can cause significant cardiac and thrombotic effects. All four patients had troponin elevations and changes noted on TTE. Two patients developed thrombi. These changes were resolved in the two patients who were seen in post-hospital follow-up. Physicians should remain vigilant when managing these patients in the Emergency Department.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"271-278"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean-Pierre Imbert, Armin Sidali, Andy Butler, Jord Lucas
{"title":"Principles for the Design, Validation, and Acceptance of Decompression Procedures.","authors":"Jean-Pierre Imbert, Armin Sidali, Andy Butler, Jord Lucas","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The 1987 UHMS Workshop on the Validation of Decompression Tables provided standards for the design, testing, and acceptance of decompression tables. Forty years later, research funding has become scarce, and diving companies no longer receive support from universities and Navy research centers. Companies build on their experience and safety culture to improve existing decompression procedures. We list principles and propose guidelines for these internal developments.</p><p><strong>Principles: </strong>Editing decompression tables is a technical activity that aims to provide a practical solution to an immediate operational problem. It relies heavily on current scientific knowledge and experience and on recognized design principles, validation protocols, and acceptance criteria.</p><p><strong>Validation: </strong>Validating decompression procedures fits into the company's Health and Safety management system. Today, decompression tables result from a risk assessment and are presented as a mitigation measure against decompression risks. Management of Change offers a step-by-step approach compatible with the UHMS recommendation for improving existing procedures.</p><p><strong>Acceptance: </strong>Accepting decompression procedures is based on the definition and measurements of relevant endpoints used as acceptance criteria. Endpoints have evolved from DCS incidence to the larger concept of decompression stress. We highlight the importance of dive monitoring in documenting procedure performances and supporting the acceptance decision.</p><p><strong>Discussion: </strong>We conclude that Management of Change can be used by diving companies to develop new or revised decompression procedures, as a complement to the 1987 UHMS recommendations. We recommend that the process be detailed in the company documentation to keep the lessons learned and inform operational personnel.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"349-362"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yan Wang, Anqi Guo, Qinqin Pu, Wanwan Cai, Long Qing
{"title":"Cerebral Dysfunction of a Diving Fisherman After Prophylactic Recompression Treatment: A Case Report.","authors":"Yan Wang, Anqi Guo, Qinqin Pu, Wanwan Cai, Long Qing","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Prophylactic recompression treatment (PRT) is an empirical treatment conducted in China for divers who conduct repetitive diving or asymptomatic insufficient decompression to eliminate residual nitrogen and microbubbles and prevent decompression sickness (DCS).</p><p><strong>Case report: </strong>We report a case of a 43-year-old healthy diving fisherman who experienced cerebral dysfunction after PRT. The fisherman suddenly experienced dizziness accompanied by vomiting, vertigo, nausea, confusion, and aphasia six hours after a 500kPa-PRT. Laboratory tests revealed a significantly elevated serum creatine kinase. No abnormalities were found by cranial computed tomography (CT), but the chest CT observed emphysema and pulmonary bullae. After undergoing another recompression treatment, the fisherman fully recovered without sequelae. Hence, it was deduced that the diver might have a cerebral arterial gas embolism (AGE).</p><p><strong>Discussion: </strong>The case suggests that although PRT for healthy diving fishermen is theoretically safe, there remains a rare possibility of decompression illness, including cerebral AGE or cerebral DCS. It is not crucial to differentiate these two conditions, as both require timely recompression treatment and, in most cases, can have a good prognosis.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"319-324"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcos J Reyes Bocanegra, Rodolfo Quintana Castro, Luis Páez Martínez, Beatriz Agame Lagunes, Peter Grube Pagola, Sandra Hernández Leyva, Julio C Ramírez Nava, Alfonso Alexander Aguilera
{"title":"Hyperbaric Oxygen Treatment Decreases Cd36 Gene Expression Through HIF-1α/PPAR-γ and Reverses Non-Alcoholic Fatty Liver Disease in Rats.","authors":"Marcos J Reyes Bocanegra, Rodolfo Quintana Castro, Luis Páez Martínez, Beatriz Agame Lagunes, Peter Grube Pagola, Sandra Hernández Leyva, Julio C Ramírez Nava, Alfonso Alexander Aguilera","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of liver fat (steatosis), which can progress to non-alcoholic steatohepatitis (NASH), cirrhosis, and cancer. NASH is estimated to affect up to 32% of the world's population. Different treatments, such as hyperbaric oxygen (HBO₂), are being investigated, but the molecular mechanisms associated with this treatment are unknown. The effect of HBO₂ on NAFLD associated with Cd36 expression was evaluated.</p><p><strong>Methods: </strong>Rats were divided into the following groups: rats that developed steatosis and consumed sucrose but did not receive HBO₂, rats with steatosis that consumed sucrose and received HBO₂, rats that developed steatosis and received HBO₂ but did not receive sucrose, and a control group. The HBO₂ groups underwent the procedure for 20 days (2.4 ATA pressure 60 min). An IYOCA hyperbaric chamber model for rats was used. The expression of HIF-1α, PPAR-γ, and Cd36 mRNA from hepatic tissue was measured with the StepOn™ real-time polymerase chain reaction (PCR) system.</p><p><strong>Results: </strong>The expression levels of hepatic HIF-1α, PPAR-γ, and Cd36 genes increased in NAFLD rats that consumed sucrose but did not receive HBO₂ compared to the control group (p <0.05). The rats that received HBO₂ with and without sucrose ingestion showed decreased expression levels of these genes compared to those with NAFLD that consumed sucrose.</p><p><strong>Discussion: </strong>HBO₂ decreased expression levels of HIF-1α and PPRA-γ, which independently or coordinately regulate Cd36 expression. Cd36 expression was significantly decreased in association with the reversal of NAFLD in rats.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"215-226"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Side Effects of Hyperbaric Oxygen Therapy.","authors":"Marvin Heyboer, William Santiago","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Like all medical treatments, hyperbaric oxygen (HBO₂) has known potential side effects. HBO₂ is provided in different clinical settings by providers and staff with differing levels of expertise. It is important to understand the potential side effects of HBO₂ in order to allow for consideration of risk and benefit in discussion with the patient who is considering HBO₂. In this chapter, we will describe and quantify these side effects. Hyperbaric oxygen therapy is the treatment of patients with 100% oxygen at higher than atmospheric pressure provided in either a monoplace chamber (single person) typically compressed with oxygen or a multiplace chamber (multiple persons) compressed with air while oxygen is delivered by a hood or mask. The benefits of treatment are the result of both primary and secondary effects. Primary effects are from increased pressure and hyperoxia, while various secondary effects are the result of controlled oxidative stress mediated by reactive oxygen and nitrogen species [1-3]. These very same primary and secondary beneficial effects can lead to side effects associated with HBO₂ including different forms of barotrauma and oxygen toxicity.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"399-414"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenny Thacker, Marc Pullis, Thomas Masters, Christopher Logue
{"title":"Laptop-style point-of-care ultrasound machines in the multiplace hyperbaric oxygen treatment chamber.","authors":"Jenny Thacker, Marc Pullis, Thomas Masters, Christopher Logue","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Point-of-care ultrasound (POCUS) has diverse uses in the critical care hyperbaric (HBO₂) environment. The use of electronic devices in a multiplace HBO₂ chamber has traditionally been limited secondary to fire risk.</p><p><strong>Methods: </strong>The primary outcome was to assess the feasibility of modern laptop-style POCUS machines in a multiplace HBO₂ chamber. A secondary aim was to assess the reliability of POCUS images obtained at different pressures in a human subject in a multiplace chamber. Testing was initially conducted with one older machine (Sonosite 180 and Sonosite Micromaxx). Subsequently, two newer machines were studied (Sonosite Edge II and Mindray M9). Machine and transducer reliability were tested by performing a battery of POCUS imaging sequences: cardiac, FAST, inferior vena cava, and thoracic. The POCUS cardiac sequences evaluated included 2D, color Doppler, and M-mode.</p><p><strong>Results: </strong>Regarding feasibility, all machines functioned well at all depths/pressures. No instances of fire or spark were observed. No surface temperatures above 1200F were recorded. Regarding reliability, all machines performed adequately and completed the entire imaging sequence.</p><p><strong>Discussion: </strong>This study demonstrates the HBO₂ chamber safety of four laptop-style POCUS machines: Sonosite 180, Sonosite Micromaxx, Sonosite Edge II, and the Mindray M9. Our results also demonstrate excellent functionality of the newer Sonosite Edge II and Mindray machines. Secondarily, the reliability of POCUS images obtained at different pressures in a human subject has been verified.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 1","pages":"51-58"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe Anemia.","authors":"Keith W Van Meter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hyperbaric oxygen (HBO₂) therapy serves as a critical bridge treatment for severe anemia when red blood cell transfusion is not possible due to religious objection, crossmatch incompatibility, or blood unavailability. Hemoglobin levels below 3.6 g/dL are clearly inadequate for tissue oxygenation, and accumulative oxygen debt exceeding 33 L/m2 within four hours of severe hemorrhage is unsurvivable. HBO₂ administered at pressures of 2 to 3 ATA dissolves sufficient oxygen directly in plasma to compensate for the deficit in hemoglobin-bound oxygen-carrying capacity, while concurrent use of hematinics and erythropoietin-stimulating strategies supports endogenous red blood cell regeneration during surface intervals between treatments. Controlled animal studies spanning from 1943 through the 1990s consistently demonstrate improved survival in HBO₂-treated groups compared to normobaric air controls across multiple hemorrhagic shock models; human case reports, case series, and one controlled prospective trial in post-hepatectomy patients further support clinical efficacy. Classified as an AHA Class IIb indication with long-standing CMS approval, HBO₂ carries a cost comparable to a single unit of packed red blood cells and maintains a favorable safety profile with few and infrequent side effects. These findings position HBO₂ as a practical, low-technology, cost-competitive intervention for reducing accumulated oxygen debt in critically anemic patients across settings including emergency departments, operative units, and intensive care environments.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 1","pages":"199-208"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Registered Nurses in Hyperbaric Medicine: Increasing Patient Compliance with Hyperbaric Oxygen Therapy.","authors":"Sydney Hurlburt, Drue Orwig","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>A quantitative analysis explored whether adding a full-time registered nurse (RN) and implementing nurse-led education and follow-up within the hyperbaric department affects patient treatment compliance and daily attendance rates.</p><p><strong>Methods: </strong>Data from two seven-month periods of hyperbaric appointments were retrospectively reviewed. Period One consists of canceled appointments from January to July 2023, when there was no dedicated nursing role in the department. Period 2 consists of canceled appointments from January to July 2024, following the addition of a full-time RN to the staffing matrix and the integration of nurse-led education into the department's workflow.</p><p><strong>Results: </strong>A chi-square test of the data showed a significant association (p < 0.001) between the addition of a full-time RN, nurse-led education, and follow-ups, and the number of canceled hyperbaric appointments. The estimated risk of cancellation prior to the interventions was 0.11, 11% higher than the rate after a dedicated nursing role was implemented (p-value < 0.001 and 95% CI for the proportion difference (0.087-0.13)). The odds of patients canceling hyperbaric appointments are 107% higher in departments without a dedicated RN role (p < 0.001). The OR=2.07, 95% CI (1.78 - 2.4).</p><p><strong>Discussion: </strong>After reviewing attendance data across two seven-month periods, it was concluded that there was an average decrease of 11% in missed appointments following the integration of a full-time RN, nurse-led education, and patient follow-up. Nursing involvement has been shown to improve compliance rates among hyperbaric patients.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 1","pages":"59-64"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sare Nur Kayacık, Fatma Zehra Gümüş Selek, Abdullah Aslan, Rabia Karabakan, Ümmühan Kıratlı
{"title":"Hyperbaric Oxygen Therapy in Stroke-Related Sudden Hearing Loss: A Case Report.","authors":"Sare Nur Kayacık, Fatma Zehra Gümüş Selek, Abdullah Aslan, Rabia Karabakan, Ümmühan Kıratlı","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Sudden sensorineural hearing loss (SSNHL) refers to a rapid decline in hearing of 30 dB or more that develops within three days, impacting at least three consecutive frequencies in one or both ears.</p><p><strong>Case report: </strong>This case report examines the improvement in hearing levels through hyperbaric oxygen treatment in a 74-year-old male patient who developed sudden hearing loss following a stroke.</p><p><strong>Discussion: </strong>After 15 days of neurological treatment, an audiological assessment revealed a 70 dB hearing loss in air conduction in the left ear. The patient initially received intravenous methylprednisolone for ten days, followed by five intratympanic steroid injections. Despite these treatments, no significant improvement in hearing was noted. The patient subsequently received 14 sessions of hyperbaric oxygen treatment, significantly improving hearing function.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 1","pages":"99-104"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}