{"title":"Granulomatous Hepatitis.","authors":"Kayla Prentice, Cynthia R L Webster","doi":"10.1016/j.cvsm.2025.03.004","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.004","url":null,"abstract":"<p><p>Granulomatous hepatitis (GH) is a subset of chronic hepatitis in which the predominant inflammatory infiltrate consists of macrophages. It can be associated with systemic granulomatous disease or confined to the liver. When associated with systemic disease, infectious causes (bacterial, fungal, protozoal, or metazoan) are more common, while disease confined to the liver is often idiopathic. Dogs with idiopathic GH most often present acutely ill, with fever, high white blood cell counts, and with ultrasound finding of a large liver often with nodules and characteristic hyperechoic parenchymal bands.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Domestic Cat Hepadnavirus, a Hepatitis B-like Virus Associated with Feline Liver Disease.","authors":"Julia A Beatty, Thomas Tu, John M Cullen","doi":"10.1016/j.cvsm.2025.03.006","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.006","url":null,"abstract":"<p><p>In 2018, a surprising finding was reported; cats are naturally infected with a virus related to hepatitis B virus (HBV), domestic cat hepadnavirus (DCH). HBV causes chronic hepatitis and hepatocellular carcinoma in people, and HBV-like viruses cause similar diseases in rodents. If DCH negatively impacts feline health then demand for diagnostics, therapeutics, and vaccination will follow. Hence, understanding pathogenic potential of DCH for cats, and the size of any associated disease burden are critical goals. Here we evaluate progress made towards these goals by reviewing published studies of DCH against the backdrop of our understanding of HBV and HBV-like viruses.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytologic Evaluation of the Liver.","authors":"Natalie Courtman, Ester Quilez","doi":"10.1016/j.cvsm.2025.03.005","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.005","url":null,"abstract":"<p><p>Liver fine needle aspiration (FNA) and bile cytology are valuable diagnostic tools for evaluating various hepatobiliary diseases in veterinary medicine. Although FNA of the liver is less invasive and faster than histopathology, it may not always provide a definitive diagnosis, but will often provide information regarding pathologic processes occurring in the liver. Cytologic evaluation is most effective when integrated with clinical information including bloodwork, imaging, and results of other diagnostic tests.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aminoaciduric Canine Hypoaminoacidemic Hepatopathy Syndrome.","authors":"John P Loftus","doi":"10.1016/j.cvsm.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.009","url":null,"abstract":"<p><p>Aminoaciduric canine hypoaminoacidemic hepatopathy syndrome is a multifaceted clinical condition that remains insufficiently understood, with its pathophysiology not yet fully delineated. Current evidence suggests a link between hypoaminoacidemia and the development of superficial necrolytic dermatitis and hepatocutaneous lesions (hypoaminoacidemia/hepatocutaneous-associated canine hepatopathy), although the underlying mechanisms driving these associations are not clearly defined. The presence of aminoaciduria, along with impaired amino acid transporter function in critical organs such as the skin, liver, and intestines, may play a significant role in the progression of this syndrome. Additionally, elevated glucagon levels may further contribute to the exacerbation of hypoaminoacidemia, worsening clinical signs.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biliary Tract Infections in Dogs.","authors":"Emma J O'Neill","doi":"10.1016/j.cvsm.2025.03.010","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.010","url":null,"abstract":"<p><p>Bacterial biliary tract infections are increasingly recognized in dogs and should be considered in any dog presenting with vomiting, anorexia, and jaundice, particularly if they have abdominal discomfort or pyrexia. Commonly recognized clinicopathologic findings include increased liver enzyme activities, hyperbilirubinemia, and an inflammatory leucogram. Hepatobiliary ultrasound forms a key component of the diagnostic approach to these cases, aiding the identification of dogs that require urgent surgical management due to biliary tract rupture, or that have another surgical condition. Ultrasound also allows guided percutaneous bile sampling to gain a sample for cytology and culture, guiding rational antimicrobial therapy.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gallbladder Mucocele.","authors":"Jody L Gookin","doi":"10.1016/j.cvsm.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.cvsm.2025.03.011","url":null,"abstract":"<p><p>Gallbladder mucocele (GBM) formation was rarely reported prior to 20 years ago and has emerged as one of the most common, deadly, and poorly understood causes of gallbladder disease in dogs. Multiple and large retrospective studies inform many aspects of diagnosis, concurrent diseases, surgical treatment, complications, and prognosis of patients with GBM. Studies of pathogenesis are fewer but are beginning to disclose underlying mechanisms for GBM formation.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hot Topics in Emergency and Critical Care","authors":"Elisa M. Mazzaferro MS, DVM, PhD","doi":"10.1016/j.cvsm.2025.01.001","DOIUrl":"10.1016/j.cvsm.2025.01.001","url":null,"abstract":"","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":"55 3","pages":"Pages ix-x"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Controversies of and Indications for Use of Glucocorticoids in the Intensive Care Unit and the Emergency Room","authors":"Yekaterina Buriko DVM, DACVECC , Ashlei Tinsley VMD","doi":"10.1016/j.cvsm.2025.01.007","DOIUrl":"10.1016/j.cvsm.2025.01.007","url":null,"abstract":"","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":"55 3","pages":"Pages 427-442"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher G. Byers DVM, DACVECC, DACVIM (SAIM), CVJ
{"title":"Crystalloids versus Colloids","authors":"Christopher G. Byers DVM, DACVECC, DACVIM (SAIM), CVJ","doi":"10.1016/j.cvsm.2025.02.001","DOIUrl":"10.1016/j.cvsm.2025.02.001","url":null,"abstract":"","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":"55 3","pages":"Pages 363-377"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}