{"title":"[Emergence of epizootic hemorrhagic disease in France in 2023:Impacts and future prospects].","authors":"Stéphan Zientara, Corinne Sailleau, Pascal Dujardin, Emmanuel Bréard, Damien Vitour","doi":"10.1684/vir.2024.1034","DOIUrl":"10.1684/vir.2024.1034","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"36-38"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2024-02-01DOI: 10.1684/vir.2024.1031
{"title":"[French society of virology in 2024: Where do we stand ?]","authors":"","doi":"10.1684/vir.2024.1031","DOIUrl":"10.1684/vir.2024.1031","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"5-8"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2024-02-01DOI: 10.1684/vir.2024.1033
Nicolas Tarbouriech, Wim P Burmeister, Beate Bersch, Frédéric Iseni
{"title":"[Poxvirus-encoded DNA replication proteins: potential targets for antivirals].","authors":"Nicolas Tarbouriech, Wim P Burmeister, Beate Bersch, Frédéric Iseni","doi":"10.1684/vir.2024.1033","DOIUrl":"10.1684/vir.2024.1033","url":null,"abstract":"<p><p>In the spring of 2022, an epidemic due to human monkeypox virus (MPXV) of unprecedented magnitude spread across all continents. Although this event was surprising in its suddenness, the resurgence of a virus from the Poxviridae family is not surprising in a world population that has been largely naïve to these viruses since the eradication of the smallpox virus in 1980 and the concomitant cessation of vaccination. Since then, a vaccine and two antiviral compounds have been developed to combat a possible return of smallpox. However, the use of these treatments during the 2022 MPXV epidemic showed certain limitations, indicating the importance of continuing to develop the therapeutic arsenal against these viruses. For several decades, efforts to understand the molecular mechanisms involved in the synthesis of the DNA genome of these viruses have been ongoing. Although many questions remain unanswered up to now, the three-dimensional structures of essential proteins, and in particular of the DNA polymerase holoenzyme in complex with DNA, make it possible to consider the development of a model for poxvirus DNA replication. In addition, these structures are valuable tools for the development of new antivirals targeting viral genome synthesis. This review will first present the molecules approved for the treatment of poxvirus infections, followed by a review of our knowledge of the replication machinery of these viruses. Finally, we will describe how these proteins could be the target of new antiviral compounds.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"23-35"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergence of Epizootic Hemorrhagic Disease in France in 2023: Impacts and Future Prospects.","authors":"Stéphan Zientara, Corinne Sailleau, Pascal Dujardin, Emmanuel Bréard, Damien Vitour","doi":"10.1684/vir.2024.1035","DOIUrl":"10.1684/vir.2024.1035","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"1-2"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Proceedings of the International Symposium of the World Association of Veterinary Laboratory Diagnosticians, 2023].","authors":"Aurore Romey, Stéphan Zientara, Labib Bakkali Kassimi","doi":"10.1684/vir.2024.1036","DOIUrl":"10.1684/vir.2024.1036","url":null,"abstract":"<p><p>The International Symposium of the World Association of Veterinary Laboratory Diagnosticians (ISWAVLD) is the unmissable biannual meeting of all diagnostic veterinary laboratories including biologists, veterinarians and other scientists involved in laboratory diagnostics. It took place at the Lyon Convention Centre (29 June-1 July 2023). It was a pleasant and enriching moment, which allowed participants to discover and/or discuss new diagnostic methods and the epidemiology of animal diseases, around all themes involving veterinarians (animal health, but also environmental and human health, and food safety).</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"39-43"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2024-02-01DOI: 10.1684/vir.2024.1038
Déborah Kiervel
{"title":"[12th International congress of plant pathology: One Health for all plants, crops and trees].","authors":"Déborah Kiervel","doi":"10.1684/vir.2024.1038","DOIUrl":"10.1684/vir.2024.1038","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"28 1","pages":"55-56"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2023-12-01DOI: 10.1684/vir.2023.1030
{"title":"[Call for applications: ANRS | Maladies infectieuses émergentes, Société française de virologie (SFV)].","authors":"","doi":"10.1684/vir.2023.1030","DOIUrl":"10.1684/vir.2023.1030","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"27 6","pages":"355-356"},"PeriodicalIF":0.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The cutaneous virome: from virology to personalized medicine].","authors":"Clément Dominguez-Lafage, Marta Laganà, Franck Gesbert, Viviana Marin-Esteban, Géraldine Schlecht-Louf, Françoise Bachelerie, Claire Deback","doi":"10.1684/vir.2023.1028","DOIUrl":"10.1684/vir.2023.1028","url":null,"abstract":"<p><p>The virome of the skin, defined as all viruses detected in the skin, represents a significant part of the microbiota. A much more recent discovery than the bacterial flora, the existence of the cutaneous virome has been revealed by recent metagenomic studies. The normal human skin virome is dominated by bacteriophages, Papillomaviridae, whose genomic diversity has proved extraordinary, and Polyomaviridae. Many yet unknown viral genomes within this virome await identification. The composition of the virome of the skin has been shown to be strictly individual and relatively stable over time, resulting from adaptation to everyone's genetics, lifestyle and mechanisms of immunological tolerance finely selected over the course of evolution. Yet little studied, the virome of the skin and all its interactions with other microbiota and the host are attracting growing interest. Indeed, constitutional or acquired alterations in the homeostasis between the commensal virome and the skin, ranging from sub-clinical viral dysbiosis to severe transformation of keratinocytes or adnexal cells, have been observed. These recent observations are stimulating the search for innovative solutions aimed at measuring or even modulating its pathological expression, with a view to personalized medicine.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"27 6","pages":"333-354"},"PeriodicalIF":0.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}