Virologie最新文献_第7页

[Emerging reoviruses: the next pandemic?] 新兴呼肠孤病毒:下一次大流行?］

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1008

Guillaume David Després, Guy Lemay

{"title":"[Emerging reoviruses: the next pandemic?]","authors":"Guillaume David Després, Guy Lemay","doi":"10.1684/vir.2023.1008","DOIUrl":"https://doi.org/10.1684/vir.2023.1008","url":null,"abstract":"As the world is experiencing the pandemic of SARS-CoV-2 responsible for COVID-19, one can wonder if members of other family of viruses could possibly emerge. Can such viruses establish a worldwide distribution with consequences similar to SARS-CoV-2? One such threat is the possible emergence of pathogenic reoviruses, especially by zoonotic transmission. Reoviruses are ubiquitous viruses exhibiting a worldwide distribution and various strains or isolates are found in many mammalian species and other vertebrates. When initially discovered, these viruses were named respiratory enteric orphan viruses (hence the acronym \"reo\") in order to reflect the fact that they could not be clearly associated with any given disease. However, this is not necessarily the case for all of these viruses, as clearly shown for some of these in animals. Significantly, there have been numerous reports of zoonotic transmission, especially from bats to humans. In this manuscript, pertinent properties of reoviruses will be first briefly presented followed by a review of available evidence for zoonotic transmission of pathogenic reoviruses to humans. Future work that appears to be needed for preparedness to the possible emergence of these viruses will then be briefly discussed.","PeriodicalId":49377,"journal":{"name":"Virologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Animal enteroviruses: a glimpse of a wide evolutionary landscape. 动物肠道病毒：广泛进化景观的一瞥。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1000

Serge Sadeuh-Mba, Joël Doté, Marie-Line Joffret, Morgane Chesnais, Typhaine Filhol, Ionela Gouandjika-Vasilache, Nolwenn Jouvenet, Maël Bessaud

{"title":"Animal enteroviruses: a glimpse of a wide evolutionary landscape.","authors":"Serge Sadeuh-Mba, Joël Doté, Marie-Line Joffret, Morgane Chesnais, Typhaine Filhol, Ionela Gouandjika-Vasilache, Nolwenn Jouvenet, Maël Bessaud","doi":"10.1684/vir.2023.1000","DOIUrl":"10.1684/vir.2023.1000","url":null,"abstract":"The genus Enterovirus (family Picornaviridae) contains numerous viruses, most of which have been identified in humans. Among them, the three serotypes of poliovirus, coxsackieviruses A and B, echoviruses, rhinoviruses and other enteroviruses (EVs) responsible in humans for a wide spectrum of clinical manifestations. There are also 60 identified EVs in different mammals. Some have been found in both humans and animals, demonstrating the possibility of zoonotic transmission of certain EVs. Compared to human EVs, genetic and epidemiological data about animal EVs are scarce. However, the detection of EVs in various species of mammals and their presence on all continents suggest that the number of EVs still to be discovered is very important. Some EVs found in animals have characteristics never seen in human EVs. Furthermore, the unique phylogenetic relationships observed between some animal EVs raise interesting questions about the rules that govern the evolution of these viruses. The aim of this review is to present the salient data on animal EVs and to highlight the questions they raise.","PeriodicalId":49377,"journal":{"name":"Virologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9846324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cell hijacking by a tick-borne flavivirus: dangerous linkages between viral RNA and cellular proteins in humans and the tick Ixodes ricinus]. [蜱传黄病毒的细胞劫持：人类和蜱中病毒 RNA 与细胞蛋白之间的危险联系]。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1006

Axel Grot, Yves Unterfinger, Sandrine Lacour, Lesley Bell-Sakyi, Houssam Attoui, Jennifer Richardson, Marion Sourisseau

引用次数: 0

2C protein of Enterovirus: key protein of viral replication and antiviral target. 肠病毒2C蛋白:病毒复制的关键蛋白和抗病毒靶点。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1002

Priscila El Kazzi, Carole Yaacoub, Ziad Fajloun, Patrice Vanelle, Etienne Decoly, Bruno Coutard, Karine Barral

{"title":"2C protein of Enterovirus: key protein of viral replication and antiviral target.","authors":"Priscila El Kazzi, Carole Yaacoub, Ziad Fajloun, Patrice Vanelle, Etienne Decoly, Bruno Coutard, Karine Barral","doi":"10.1684/vir.2023.1002","DOIUrl":"https://doi.org/10.1684/vir.2023.1002","url":null,"abstract":"Enteroviruses (EVs) include many human pathogens of increasing public health concern. These EVs are often associated with mild clinical manifestations, but they can lead to serious complications such as encephalitis, meningitis, pneumonia, myocarditis or poliomyelitis. Despite significant advances, there is no approved antiviral therapy for the treatment of enterovirus infections. Due to the high genotypic diversity of EVs, molecules targeting highly conserved viral proteins may be considered for developing a pan-EV treatment. In this regard, the ATPase/Helicase 2C, which is a highly conserved non-structural protein among EVs, has essential functions for viral replication and is therefore an attractive antiviral target. Recent functional and structural studies on the 2C protein led to the identification of molecules showing ex vivo anti-EV activity and associated with resistance mutations on the coding sequence of the 2C protein. This review presents the current state of knowledge about the 2C protein from an antiviral target perspective and the mode of action of specific inhibitors for this therapeutic target.","PeriodicalId":49377,"journal":{"name":"Virologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9869575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Emerging reoviruses: the next pandemic? 新出现的呼肠孤病毒:下一次大流行?

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1009

Guillaume David Després, Guy Lemay

{"title":"Emerging reoviruses: the next pandemic?","authors":"Guillaume David Després, Guy Lemay","doi":"10.1684/vir.2023.1009","DOIUrl":"https://doi.org/10.1684/vir.2023.1009","url":null,"abstract":"As the world is experiencing the pandemic of SARS-CoV-2 responsible for COVID-19, one can wonder if members of other family of viruses could possibly emerge. Can such viruses establish a worldwide distribution with consequences similar to SARS-CoV-2? One such threat is the possible emergence of pathogenic reoviruses, especially by zoonotic transmission. Reoviruses are ubiquitous viruses exhibiting a worldwide distribution and various strains or isolates are found in many mammalian species and other vertebrates. When initially discovered, these viruses were named respiratory enteric orphan viruses (hence the acronym \"reo\") in order to reflect the fact that they could not be clearly associated with any given disease. However, this is not necessarily the case for all of these viruses, as clearly shown for some of these in animals. Significantly, there have been numerous reports of zoonotic transmission, especially from bats to humans. In this manuscript, pertinent properties of reoviruses will be first briefly presented followed by a review of available evidence for zoonotic transmission of pathogenic reoviruses to humans. Future work that appears to be needed for preparedness to the possible emergence of these viruses will then be briefly discussed.","PeriodicalId":49377,"journal":{"name":"Virologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9869572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[2C protein of Enterovirus: key protein of viral replication and antiviral target]. [肠病毒2C蛋白:病毒复制关键蛋白及抗病毒靶点]。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1001

Priscila El Kazzi, Carole Yaacoub, Ziad Fajloun, Patrice Vanelle, Etienne Decroly, Bruno Coutard, Karine Barral

引用次数: 0

[Animal enteroviruses: a glimpse of a wide evolutionary landscape]. [动物肠道病毒:广泛进化图景的一瞥]。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.0999

Serge Sadeuh-Mba, Joël Doté, Marie-Line Joffret, Morgane Chesnais, Typhaine Filhol, Ionela Gouandjika-Vasilache, Nolwenn Jouvenet, Maël Bessaud

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引用次数: 0

[Comparative study of innate immune gene landscape in bat cells]. [蝙蝠细胞先天免疫基因景观的比较研究]。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1005

Sophie-Marie Aicher, Amandine Chantharath, Etienne Kornobis, Niklas Endres, Quang Dinh Tran, Ivan Nombela Diaz, Juliana Pipoli Da Fonseca, Marcel Müller, Arinjay Banerjee, Nolwenn Jouvenet

引用次数: 0

[Identification of interferon-stimulated genes that interfere with the replication of West Nile virus and Usutu virus]. [干扰素刺激基因的鉴定干扰西尼罗河病毒和Usutu病毒的复制]。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1004

Jim Zoladek, Marion Cannac, Matéo Cartron, Thomas Léocadie, Sam J Wilson, Sébastien Nisole

引用次数: 0

[Renaud-Mahieux prizes - XXV^th JFV]. 【Renaud Mahieux奖-第二十五届JFV】。

IF 0.9 4区医学

Virologie Pub Date : 2023-06-01 DOI: 10.1684/vir.2023.1003

Sébastien Nisole, David Gilmer

引用次数: 0