VirologiePub Date : 2025-04-25DOI: 10.1684/vir.2025.1084
David Olagnier, Tommy Alain
{"title":"[The 16<sup>th</sup> Annual International Oncolytic Virotherapy Conference (IOVC) in Rotterdam: For the dreamers and doers of oncolytic virotherapy].","authors":"David Olagnier, Tommy Alain","doi":"10.1684/vir.2025.1084","DOIUrl":"https://doi.org/10.1684/vir.2025.1084","url":null,"abstract":"<p><p>From October 27-30 2024, the 16th International Oncolytic Virotherapy Conference (IOVC) was held in Rotterdam, the Netherlands, a city that mirrors the spirit of resilience, conviction, and innovation of researchers in the field of oncolytic viruses. Rotterdam, renowned for its post-war rebuilding with cutting-edge architecture designed for a bright future in mind, provided a fitting reflection that oncolytic virotherapy is at a turning point in its evolution. Hosted at the International Congress Center De Doelen, the event gathered clinicians, scientists, and biotech leaders to showcase the most up-to-date clinical applications, novel viral platforms, targeted mechanisms, and immune-modulating strategies that will push the boundaries of cancer immunotherapy into the next era. We present here an overview of this engaging meeting and offer our own perspectives on where to dream and continue to build.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 3","pages":"0"},"PeriodicalIF":0.7,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-05DOI: 10.1684/vir.2025.1077
David Olagnier, Tommy Alain
{"title":"The 16th Annual International Oncolytic Virotherapy Conference (IOVC) in Rotterdam: For the dreamers and doers of oncolytic virotherapy.","authors":"David Olagnier, Tommy Alain","doi":"10.1684/vir.2025.1077","DOIUrl":"https://doi.org/10.1684/vir.2025.1077","url":null,"abstract":"<p><p>From October 27-30 2024, the 16th International Oncolytic Virotherapy Conference (IOVC) was held in Rotterdam, the Netherlands, a city that mirrors the spirit of resilience, conviction, and innovation of researchers in the field of oncolytic viruses. Rotterdam, renowned for its post-war rebuilding with cutting-edge architecture designed for a bright future in mind, provided a fitting reflection that oncolytic virotherapy is at a turning point in its evolution. Hosted at the International Congress Center De Doelen, the event gathered clinicians, scientists, and biotech leaders to showcase the most up-to-date clinical applications, novel viral platforms, targeted mechanisms, and immune-modulating strategies that will push the boundaries of cancer immunotherapy into the next era. We present here an overview of this engaging meeting and offer our own perspectives on where to dream and continue to build.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 3","pages":"0"},"PeriodicalIF":0.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-02DOI: 10.1684/vir.2025.1080
Pierre Lebon, Paul Mandon, Henri Agut
{"title":"[Attachment to red blood cells, a very useful property of certain viruses].","authors":"Pierre Lebon, Paul Mandon, Henri Agut","doi":"10.1684/vir.2025.1080","DOIUrl":"https://doi.org/10.1684/vir.2025.1080","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 3","pages":"0"},"PeriodicalIF":0.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1078
Hélène Dutartre, Francesca Fiorini, Denis Gerlier, Henri Gruffat, Patrick Lomonte, Pierre-Yves Lozach, Mathieu Mateo
{"title":"[Lyon, at the center of the global virology research challenge].","authors":"Hélène Dutartre, Francesca Fiorini, Denis Gerlier, Henri Gruffat, Patrick Lomonte, Pierre-Yves Lozach, Mathieu Mateo","doi":"10.1684/vir.2025.1078","DOIUrl":"https://doi.org/10.1684/vir.2025.1078","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"59-63"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1083
{"title":"Index par auteur et par numéro de résumé.","authors":"","doi":"10.1684/vir.2025.1083","DOIUrl":"https://doi.org/10.1684/vir.2025.1083","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"170-175"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1081
{"title":"Programme des XXVIIes Journées francophones de virology 23, 24 & 25 avril 2025.","authors":"","doi":"10.1684/vir.2025.1081","DOIUrl":"https://doi.org/10.1684/vir.2025.1081","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"68-69"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-02-01DOI: 10.1684/vir.2025.1073
Mariangela Cavarelli
{"title":"[Ghosts of the virus : unmasking the persistent threat of SARS-CoV-2 in Long COVID].","authors":"Mariangela Cavarelli","doi":"10.1684/vir.2025.1073","DOIUrl":"10.1684/vir.2025.1073","url":null,"abstract":"<p><p>Long COVID has emerged as a debilitating condition, severely impacting the daily functioning and quality of life of affected individuals. The pathogenesis of Long COVID is complex and multifactorial, involving immune dysregulation, persistent inflammation, and potential reactivation of other pathogens. A key driver of Long COVID is the potential persistence of SARS-CoV-2 in various tissues beyond the respiratory tract, leading to the formation of viral reservoirs that contribute to ongoing symptoms, several months after initial infection. These reservoirs have been suggested in the gastrointestinal tract, central nervous system, cardiovascular system, and other tissues, often persisting months after the initial infection. Additionally, viral RNA and proteins in these tissues are associated with chronic inflammation and immune system disruptions, which are primary contributors to Long COVID symptoms. This article explores the mechanisms and consequences of SARS-CoV-2 persistence in respiratory and non-respiratory tissues, highlighting its impact on the immune system and underscoring critical areas for future research to improve outcomes for individuals suffering from Long COVID.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 1","pages":"41-53"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-02-01DOI: 10.1684/vir.2025.1074
Mariangela Cavarelli
{"title":"Ghosts of the virus : unmasking the persistent threat of SARS-CoV-2 in Long COVID.","authors":"Mariangela Cavarelli","doi":"10.1684/vir.2025.1074","DOIUrl":"10.1684/vir.2025.1074","url":null,"abstract":"<p><p>Long COVID has emerged as a debilitating condition, severely impacting the daily functioning and quality of life of affected individuals. The pathogenesis of Long COVID is complex and multifactorial, involving immune dysregulation, persistent inflammation, and potential reactivation of other pathogens. A key driver of Long COVID is the potential persistence of SARS-CoV-2 in various tissues beyond the respiratory tract, leading to the formation of viral reservoirs that contribute to ongoing symptoms, several months after initial infection. These reservoirs have been suggested in the gastrointestinal tract, central nervous system, cardiovascular system, and other tissues, often persisting months after the initial infection. Additionally, viral RNA and proteins in these tissues are associated with chronic inflammation and immune system disruptions, which are primary contributors to Long COVID symptoms. This article explores the mechanisms and consequences of SARS-CoV-2 persistence in respiratory and non-respiratory tissues, highlighting its impact on the immune system and underscoring critical areas for future research to improve outcomes for individuals suffering from Long COVID.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 1","pages":"57-68"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}